miR‐21‐regulated M2 polarization of macrophage is involved in arsenicosis‐induced hepatic fibrosis through the activation of hepatic stellate cells

Dihydroartemisinin Prevents Progression and Metastasis of Head and Neck Squamous Cell Carcinoma by Inhibiting Polarization of Macrophages in Tumor Microenvironment

(2020) Ran Chen et al.   OncoTargets and Therapy

An Overview on Arsenic Trioxide-Induced Cardiotoxicity

(2019) Vadavanath Prabhakaran Vineetha et al.   Cardiovascular Toxicology

Metal carcinogen exposure induces cancer stem cell-like property through epigenetic reprograming: A novel mechanism of metal carcinogenesis

(2019) Zhishan Wang et al.   SEMINARS IN CANCER BIOLOGY

The role of arsenic in obesity and diabetes

(2019) Tahereh Farkhondeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mesenchymal stromal cell-derived exosomes attenuate myocardial ischaemia-reperfusion injury through miR-182-regulated macrophage polarization

(2019) Jinxuan Zhao et al.   CARDIOVASCULAR RESEARCH

Effects of parvovirus B19 in vitro infection on monocytes from systemic sclerosis patients: enhanced inflammatory pathways by caspase-1 activation and cytokine production

(2019) Krystyna Zakrzewska et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

MicroRNAs play an important role in contributing to arsenic susceptibility in the chronically exposed individuals of West Bengal, India

(2019) Nilanjana Banerjee et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation

(2019) Li Sun et al.   LIFE SCIENCES

Activin-A causes Hepatic stellate cell activation via the induction of TNFα and TGFβ in Kupffer cells

(2018) Foteini Kiagiadaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hypoxic tumor-derived exosomal miR-301a mediates M2 macrophage polarization via PTEN/PI3Kγ to promote pancreatic cancer metastasis

(2018) Xiaofeng Wang et al.   CANCER RESEARCH

Determinants of fibrosis progression and regression in NASH

(2018) Detlef Schuppan et al.   JOURNAL OF HEPATOLOGY

Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways

(2018) Xiaofan Guo et al.   ONCOGENE

Liver fibrosis

(2018) M. Merve Aydin et al.   Turkish Journal of Gastroenterology

iTRAQ-based quantitative proteomic analysis reveals important metabolic pathways for arsenic-induced liver fibrosis in rats

(2018) Shunhua Wu et al.   Scientific Reports

MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis

(2018) Le Tao et al.   ARCHIVES OF TOXICOLOGY

Arsenic induces fibrogenic changes in human kidney epithelial cells potentially through epigenetic alterations in DNA methylation

(2018) Yu-Wei Chang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A review on arsenic carcinogenesis: Epidemiology, metabolism, genotoxicity and epigenetic changes

(2018) Qing Zhou et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

(2018) David Fernández-Ramos et al.   Cell Death & Disease

Spleen-Kidney Supplementing Formula Alleviates Renal Fibrosis in Diabetic Rats via TGF-β1-miR-21-PTEN Signaling Pathway

(2018) Chunyu Tian et al.   Evidence-based Complementary and Alternative Medicine

Long noncoding RNA HOTTIP mediates SRF expression through sponging miR‐150 in hepatic stellate cells

(2018) Jianjian Zheng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Tumor-derived exosomal microRNAs and proteins as modulators of macrophage function

(2018) Maryam Moradi-Chaleshtori et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis

(2018) Hsin-Chieh Tsay et al.   JOURNAL OF HEPATOLOGY

Suppression of SUN2 by DNA methylation is associated with HSCs activation and hepatic fibrosis

(2018) Xin Chen et al.   Cell Death & Disease

Natural Background and Anthropogenic Arsenic Enrichment in Florida Soils, Surface Water, and Groundwater: A Review with a Discussion on Public Health Risk

(2018) Thomas Missimer et al.   International Journal of Environmental Research and Public Health

microRNA-based prophylaxis in a mouse model of cirrhosis and liver cancer

(2018) Elisa Callegari et al.   Molecular Therapy-Nucleic Acids

miR-100 maintains phenotype of tumor-associated macrophages by targeting mTOR to promote tumor metastasis via Stat5a/IL-1ra pathway in mouse breast cancer

(2018) Wei Wang et al.   Oncogenesis

IL-33/ST2 Axis in Organ Fibrosis

(2018) Ourania S. Kotsiou et al.   Frontiers in Immunology

Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization

(2017) Eleni Vergadi et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Macrophage Phenotype in Liver Injury and Repair

(2017) Y.-Y. Sun et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Attenuative role of mangiferin in oxidative stress-mediated liver dysfunction in arsenic-intoxicated murines

(2016) Sukanya Saha et al.   BIOFACTORS

Effects of Arsenic in Drinking Water on Risk of Hepatitis or Cirrhosis in Persons With and Without Chronic Viral Hepatitis

(2016) Ling-I. Hsu et al.   Clinical Gastroenterology and Hepatology

Modulating macrophage polarization with divalent cations in nanostructured titanium implant surfaces

(2016) Chung-Ho Lee et al.   NANOTECHNOLOGY

MicroRNA-21 activation of ERK signaling via PTEN is involved in arsenite-induced autophagy in human hepatic L-02 cells

(2016) Xinlu Liu et al.   TOXICOLOGY LETTERS

Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouse

(2015) Pedro Melgar-Lesmes et al.   JOURNAL OF HEPATOLOGY

The IL-6/STAT3 pathway via miR-21 is involved in the neoplastic and metastatic properties of arsenite-transformed human keratinocytes

(2015) Xiaolin Lu et al.   TOXICOLOGY LETTERS

Macrophage migration inhibitory factor is required for recruitment of scar-associated macrophages during liver fibrosis

(2014) Mark A. Barnes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hepatic Localization of Macrophage Phenotypes during Fibrogenesis and Resolution of Fibrosis in Mice and Humans

(2014) Leonie Beljaars et al.   Frontiers in Immunology

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytotoxicity and gene expression changes induced by inorganic and organic trivalent arsenicals in human cells

(2013) Puttappa R. Dodmane et al.   TOXICOLOGY

Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

(2013) Fei Luo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

(2011) Alexandre Louvet et al.   HEPATOLOGY

Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib

(2011) Yuqing Liu et al.   JOURNAL OF HEPATOLOGY

Chronic arsenic toxicity: Studies in West Bengal, India

(2011) Debendranath Guha Mazumder et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL