Dysregulation of microRNAs in metal-induced angiogenesis and carcinogenesis

Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer

(2021) Mayukh Banerjee et al.   ARCHIVES OF TOXICOLOGY

MicroRNA-363-3p promotes apoptosis in response to cadmium-induced renal injury by down-regulating phosphoinositide 3-kinase expression

(2021) Jiabin Chen et al.   TOXICOLOGY LETTERS

Cadmium-Induced Renal Cell Toxicity Is Associated With MicroRNA Deregulation

(2020) J. Lemaire et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Structure, function, and biosynthesis of nickel‐dependent enzymes

(2020) Marila Alfano et al.   PROTEIN SCIENCE

The Role of Reactive Oxygen Species in Arsenic Toxicity

(2020) Yuxin Hu et al.   Biomolecules

Melatonin Antagonizes Nickel-Induced Aerobic Glycolysis by Blocking ROS-Mediated HIF-1α/miR210/ISCU Axis Activation

(2020) Mindi He et al.   Oxidative Medicine and Cellular Longevity

The Effects of Cadmium Toxicity

(2020) Giuseppe Genchi et al.   International Journal of Environmental Research and Public Health

Toxic-Metal-Induced Alteration in miRNA Expression Profile as a Proposed Mechanism for Disease Development

(2020) David R. Wallace et al.   Cells

MicroRNA-204-5p regulates apoptosis by targeting Bcl2 in rat ovarian granulosa cells exposed to cadmium†

(2020) Ping Zhong et al.   BIOLOGY OF REPRODUCTION

MiR ‐122‐5p and miR ‐326‐3p promote cadmium‐induced NRK‐52E cell apoptosis by downregulating PLD1

(2020) Wenya Yuan et al.   ENVIRONMENTAL TOXICOLOGY

miR-21 mediates nickel nanoparticle-induced pulmonary injury and fibrosis

(2020) Yiqun Mo et al.   Nanotoxicology

MicroRNA-15b in extracellular vesicles from arsenite-treated macrophages promotes the progression of hepatocellular carcinomas by blocking the LATS1-mediated Hippo pathway

(2020) Junjie Li et al.   CANCER LETTERS

Circulating differential miRNAs profiling and expression in hexavalent chromium exposed electroplating workers

(2020) Junlin Jia et al.   CHEMOSPHERE

Arsenic-induced HER2 promotes proliferation, migration and angiogenesis of bladder epithelial cells via activation of multiple signaling pathways in vitro and in vivo

(2020) Qing Zhou et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Environmental exposure to cadmium and risk of thyroid cancer from national industrial complex areas: A population-based cohort study

(2020) Eunjung Park et al.   CHEMOSPHERE

Metals and Mechanisms of Carcinogenesis

(2019) Qiao Yi Chen et al.   Annual Review of Pharmacology and Toxicology

Metal carcinogen exposure induces cancer stem cell-like property through epigenetic reprograming: A novel mechanism of metal carcinogenesis

(2019) Zhishan Wang et al.   SEMINARS IN CANCER BIOLOGY

Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth

(2019) Lin Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cadmium Exposure and Risk of Breast Cancer by Histological and Tumor Receptor Subtype in White Caucasian Women: A Hospital-Based Case-Control Study

(2019) Loreta Strumylaite et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cadmium exposure upregulates SNAIL through miR-30 repression in human lung epithelial cells

(2019) Vinay Singh Tanwar et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chronic Hexavalent Chromium Exposure Induces Cancer Stem Cell-Like Property and Tumorigenesis by Increasing c-Myc Expression

(2019) Zhishan Wang et al.   TOXICOLOGICAL SCIENCES

Overexpression of hsa-miR-186 induces chromosomal instability in arsenic-exposed human keratinocytes

(2019) Jiguo Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Exposure to metal fumes and circulating miRNAs in Algerian welders

(2019) Imene Amrani et al.   INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Cadmium exposure and prostate cancer insights mechanisms and perspectives

(2018) Caterina Ledda   Frontiers in Bioscience-Landmark

Differentially Expressed mRNA Targets of Differentially Expressed miRNAs Predict Changes in the TP53 Axis and Carcinogenesis-Related Pathways in Human Keratinocytes Chronically Exposed to Arsenic

(2018) Laila Al-Eryani et al.   TOXICOLOGICAL SCIENCES

Upregulation of histone-lysine methyltransferases plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation

(2018) Zhishan Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cells

(2018) Chao Chen et al.   TOXICOLOGY IN VITRO

Circ008913, via miR-889 regulation of DAB2IP/ZEB1, is involved in the arsenite-induced acquisition of CSC-like properties by human keratinocytes in carcinogenesis

(2018) Tian Xiao et al.   Metallomics

miRNA-182-5p, via HIF2α, contributes to arsenic carcinogenesis: Evidence from human renal epithelial cells

(2018) Xin Fang et al.   Metallomics

miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions

(2018) Laila Al-Eryani et al.   PLoS One

Cadmium-mediated miR-30a-GRP78 leads to JNK-dependent autophagy in chicken kidney

(2018) Qunxiang Shi et al.   CHEMOSPHERE

Post-transcriptional control of miRNA biogenesis

(2018) Gracjan Michlewski et al.   RNA

NF-κB-regulated miR-155, via repression of QKI, contributes to the acquisition of CSC-like phenotype during the neoplastic transformation of hepatic cells induced by arsenite

(2017) Chao Chen et al.   MOLECULAR CARCINOGENESIS

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

Nickel and cadmium-induced SLBP depletion: A potential pathway to metal mediated cellular transformation

(2017) Ashley Jordan et al.   PLoS One

CircLRP6 Regulation of ZEB1 via miR-455 Is Involved in the Epithelial-Mesenchymal Transition During Arsenite-Induced Malignant Transformation of Human Keratinocytes

(2017) Junchao Xue et al.   TOXICOLOGICAL SCIENCES

Alterations of miRNAs and Their Potential Roles in Arsenite-Induced Transformation of Human Bronchial Epithelial Cells

(2017) Shiyan Gu et al.   Genes

Upregulation of microRNA-4417 and Its Target Genes Contribute to Nickel Chloride-promoted Lung Epithelial Cell Fibrogenesis and Tumorigenesis

(2017) Chih-Hsien Wu et al.   Scientific Reports

Regulatory role of miR-125a/b in the suppression by selenium of cadmium-induced apoptosis via the mitochondrial pathway in LLC-PK1 cells

(2016) Zhimin Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

miR-579-3p controls melanoma progression and resistance to target therapy

(2016) Luigi Fattore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitigation of arsenic-induced acquired cancer phenotype in prostate cancer stem cells by miR-143 restoration

(2016) Ntube N.O. Ngalame et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

MicroRNA-21 activation of ERK signaling via PTEN is involved in arsenite-induced autophagy in human hepatic L-02 cells

(2016) Xinlu Liu et al.   TOXICOLOGY LETTERS

miRNA Deregulation in Cancer Cells and the Tumor Microenvironment

(2016) R. Rupaimoole et al.   Cancer Discovery

Role and mechanism of miR-222 in arsenic-transformed cells for inducing tumor growth

(2016) Min Wang et al.   Oncotarget

Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling

(2016) Poyil Pratheeshkumar et al.   Oncotarget

HIF-2α, acting via miR-191, is involved in angiogenesis and metastasis of arsenite-transformed HBE cells

(2016) Wenchao Xu et al.   Toxicology Research

My Lifelong Passion for Biochemistry and Anaerobic Microorganisms

(2015) Rudolf Kurt Thauer   Annual Review of Microbiology

Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy

(2015) Jun He et al.   Autophagy

Involvement of Epigenetics and EMT-Related miRNA in Arsenic-Induced Neoplastic Transformation and Their Potential Clinical Use

(2015) C. Michailidi et al.   Cancer Prevention Research

Regulatory circuit of PKM2/NF-κB/miR-148a/152-modulated tumor angiogenesis and cancer progression

(2015) Q Xu et al.   ONCOGENE

Dysregulation of microRNA biogenesis and gene silencing in cancer

(2015) Akiko Hata et al.   Science Signaling

Cadmium Induces Histone H3 Lysine Methylation by Inhibiting Histone Demethylase Activity

(2015) Chunlian Xiao et al.   TOXICOLOGICAL SCIENCES

MicroRNA-21, up-regulated by arsenite, directs the epithelial–mesenchymal transition and enhances the invasive potential of transformed human bronchial epithelial cells by targeting PDCD4

(2015) Fei Luo et al.   TOXICOLOGY LETTERS

Nickel may contribute to EGFR mutation and synergistically promotes tumor invasion in EGFR-mutated lung cancer via nickel-induced microRNA-21 expression

(2015) Yu-Hu Chiou et al.   TOXICOLOGY LETTERS

Low-Dose Cadmium Upregulates VEGF Expression in Lung Adenocarcinoma Cells

(2015) Fuhong Liu et al.   International Journal of Environmental Research and Public Health

MicroRNAs-mRNAs Expression Profile and Their Potential Role in Malignant Transformation of Human Bronchial Epithelial Cells Induced by Cadmium

(2015) Qun Liu et al.   Biomed Research International

Dysregulation of microRNA biogenesis and gene silencing in cancer

(2015) Akiko Hata et al.   Science Signaling

Chronic Arsenic Exposure and Angiogenesis in Human Bronchial Epithelial Cells via the ROS/miR-199a-5p/HIF-1α/COX-2 Pathway

(2014) Jun He et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

MicroRNA-191, by promoting the EMT and increasing CSC-like properties, is involved in neoplastic and metastatic properties of transformed human bronchial epithelial cells

(2014) Wenchao Xu et al.   MOLECULAR CARCINOGENESIS

Aberrant microRNA Expression Likely Controls RAS Oncogene Activation During Malignant Transformation of Human Prostate Epithelial and Stem Cells by Arsenic

(2014) Ntube N. O. Ngalame et al.   TOXICOLOGICAL SCIENCES

miR-3940-5p associated with genetic damage in workers exposed to hexavalent chromium

(2014) Yang Li et al.   TOXICOLOGY LETTERS

The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB

(2014) Rongrong Jiang et al.   TOXICOLOGY LETTERS

MicroRNAs in cancer: biomarkers, functions and therapy

(2014) Josie Hayes et al.   TRENDS IN MOLECULAR MEDICINE

MiRNA-210 modulates a nickel-induced cellular energy metabolism shift by repressing the iron–sulfur cluster assembly proteins ISCU1/2 in Neuro-2a cells

(2014) M He et al.   Cell Death & Disease

Arsenic exposure is associated with DNA hypermethylation of the tumor suppressor gene p16

(2014) Guangming Lu et al.   Journal of Occupational Medicine and Toxicology

Oxidative stress and DNA repair and detoxification gene expression in adolescents exposed to heavy metals living in the Milazzo-Valle del Mela area (Sicily, Italy)

(2014) Gabriele Pizzino et al.   Redox Biology

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

The Alteration of MiR-222 and Its Target Genes in Nickel-Induced Tumor

(2013) Jing Zhang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers

(2013) Xu Qian et al.   CELL CYCLE

Roles of EGFR, PI3K, AKT, and mTOR in Heavy Metal-Induced Cancer

(2013) Richard L. Carpenter et al.   CURRENT CANCER DRUG TARGETS

The Broad Scope of Health Effects from Chronic Arsenic Exposure: Update on a Worldwide Public Health Problem

(2013) Marisa F. Naujokas et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Arsenic exposure triggers a shift in microRNA expression

(2013) Elena Sturchio et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Repression of miR-143 Mediates Cr (VI)–Induced Tumor Angiogenesis via IGF-IR/IRS1/ERK/IL-8 Pathway

(2013) Jun He et al.   TOXICOLOGICAL SCIENCES

Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

(2013) Fei Luo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Angiogenesis, mediated by miR-21, is involved arsenite-induced carcinogenesis

(2013) Yue Zhao et al.   TOXICOLOGY LETTERS

Hyper-methylated miR-203 dysregulates ABL1 and contributes to the nickel-induced tumorigenesis

(2013) Jing Zhang et al.   TOXICOLOGY LETTERS

Nickel and Epigenetic Gene Silencing

(2013) Hong Sun et al.   Genes

Chromium (VI) induces both bulky DNA adducts and oxidative DNA damage at adenines and guanines in the p53 gene of human lung cells

(2012) H. Arakawa et al.   CARCINOGENESIS

MicroRNA-152 targets DNA methyltransferase 1 in NiS-transformed cells via a feedback mechanism

(2012) Weidong Ji et al.   CARCINOGENESIS

MicroRNAs in Stress Signaling and Human Disease

(2012) Joshua T. Mendell et al.   CELL

Molecular and Cellular Mechanisms of Hexavalent Chromium-Induced Lung Cancer: An Updated Perspective

(2012) A. M. Urbano et al.   CURRENT DRUG METABOLISM

MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

(2012) Marilena V. Iorio et al.   EMBO Molecular Medicine

Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylation

(2012) Jun He et al.   EMBO REPORTS

Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation

(2012) Min Ling et al.   FREE RADICAL BIOLOGY AND MEDICINE

The control of histone methylation and gene expression by oxidative stress, hypoxia, and metals

(2012) Yana Chervona et al.   FREE RADICAL BIOLOGY AND MEDICINE

The effect of exposure to carcinogenic metals on histone tail modifications and gene expression in human subjects

(2012) Adriana Arita et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Carcinogenic metals and the epigenome: understanding the effect of nickel, arsenic, and chromium

(2012) Yana Chervona et al.   Metallomics

MicroRNA-21 Modulates Chemosensitivity of Breast Cancer Cells to Doxorubicin by Targeting PTEN

(2011) Zhao-Xia Wang et al.   ARCHIVES OF MEDICAL RESEARCH

Bioavailability of Cadmium in Inexpensive Jewelry

(2011) Jeffrey D. Weidenhamer et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Environmental epigenetics in metal exposure

(2011) Ricardo Martinez-Zamudio et al.   Epigenetics

MicroRNA-181b and microRNA-9 mediate arsenic-induced angiogenesis via NRP1

(2011) Yi Cui et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis

(2011) Qing Xu et al.   NUCLEIC ACIDS RESEARCH

Role and Mechanism of Arsenic in Regulating Angiogenesis

(2011) Ling-Zhi Liu et al.   PLoS One

MiR-21 Induced Angiogenesis through AKT and ERK Activation and HIF-1α Expression

(2011) Ling-Zhi Liu et al.   PLoS One

MicroRNAs in the Pathogenesis of Cancer

(2011) Francesca Lovat et al.   SEMINARS IN ONCOLOGY

Cadmium Increases HIF-1 and VEGF Expression through ROS, ERK, and AKT Signaling Pathways and Induces Malignant Transformation of Human Bronchial Epithelial Cells

(2011) Yi Jing et al.   TOXICOLOGICAL SCIENCES

miR-190-Mediated Downregulation of PHLPP Contributes to Arsenic-Induced Akt Activation and Carcinogenesis

(2011) Kevin Beezhold et al.   TOXICOLOGICAL SCIENCES

Reversal and Prevention of Arsenic-Induced Human Bronchial Epithelial Cell Malignant Transformation by microRNA-200b

(2011) Zhishan Wang et al.   TOXICOLOGICAL SCIENCES

Exposure to Metal-Rich Particulate Matter Modifies the Expression of Candidate MicroRNAs in Peripheral Blood Leukocytes

(2010) Valentina Bollati et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Effects of arsenic exposure on DNA methylation and epigenetic gene regulation

(2010) John F Reichard et al.   Epigenomics

Oceanic nickel depletion and a methanogen famine before the Great Oxidation Event

(2009) Kurt O. Konhauser et al.   NATURE

Nickel compounds induce phosphorylation of histone H3 at serine 10 by activating JNK-MAPK pathway

(2008) Q. Ke et al.   CARCINOGENESIS

A Systematic Comparison of the Actual, Potential, and Theoretical Health Effects of Cobalt and Chromium Exposures from Industry and Surgical Implants

(2008) Gemma M. Keegan et al.   CRITICAL REVIEWS IN TOXICOLOGY