Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and promoting cell proliferation

The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence

(2017) Chin-Chi Kuo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

miR-217 suppresses proliferation, migration, and invasion promoting apoptosis via targeting MTDH in hepatocellular carcinoma

(2017) Mao Zhang et al.   ONCOLOGY REPORTS

Increased microRNA 21 expression contributes to arsenic induced skin lesions, skin cancers and respiratory distress in chronically exposed individuals

(2017) Nilanjana Banerjee et al.   TOXICOLOGY

The lncRNA MALAT1, acting through HIF-1α stabilization, enhances arsenite-induced glycolysis in human hepatic L-02 cells

(2016) Fei Luo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hsa_circ_0001649: A circular RNA and potential novel biomarker for hepatocellular carcinoma

(2016) Meilin Qin et al.   Cancer Biomarkers

STAT3-regulated exosomal miR-21 promotes angiogenesis and is involved in neoplastic processes of transformed human bronchial epithelial cells

(2016) Yi Liu et al.   CANCER LETTERS

An ornamental plant targets epigenetic signaling to block cancer stem cell-driven colon carcinogenesis

(2016) Ishfaq Ahmed et al.   CARCINOGENESIS

Influence of MRP1 G1666A and GSTP1 Ile105Val genetic variants on the urinary and blood arsenic levels of Turkish smelter workers

(2016) Dilek Kaya-Akyüzlü et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Comprehensive Circular RNA Profiling Reveals That hsa_circ_0005075, a New Circular RNA Biomarker, Is Involved in Hepatocellular Crcinoma Development

(2016) Xingchen Shang et al.   MEDICINE

Mitigation of arsenic-induced acquired cancer phenotype in prostate cancer stem cells by miR-143 restoration

(2016) Ntube N.O. Ngalame et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance

(2016) Erika Lasda et al.   PLoS One

Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction

(2015) Kobina Essandoh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

Epimutagenesis: A prospective mechanism to remediate arsenic-induced toxicity

(2015) Somnath Paul et al.   ENVIRONMENT INTERNATIONAL

Inner Workings of Arsenic: DNA Methylation Targets Offer Clues to Mechanisms of Toxicity

(2015) Lindsey Konkel   ENVIRONMENTAL HEALTH PERSPECTIVES

MicroRNA-188-5p suppresses tumor cell proliferation and metastasis by directly targeting FGF5 in hepatocellular carcinoma

(2015) Feng Fang et al.   JOURNAL OF HEPATOLOGY

Posttranscriptional silencing of the lncRNA MALAT1 by miR-217 inhibits the epithelial–mesenchymal transition via enhancer of zeste homolog 2 in the malignant transformation of HBE cells induced by cigarette smoke extract

(2015) Lu Lu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Exosomal miR-21 derived from arsenite-transformed human bronchial epithelial cells promotes cell proliferation associated with arsenite carcinogenesis

(2014) Yuan Xu et al.   ARCHIVES OF TOXICOLOGY

Complementary Sequence-Mediated Exon Circularization

(2014) Xiao-Ou Zhang et al.   CELL

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Silencing of Long Noncoding RNA MALAT1 by miR-101 and miR-217 Inhibits Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma Cells

(2014) Xinyu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression

(2014) Yoonjin Lee et al.   NATURE

The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB

(2014) Rongrong Jiang et al.   TOXICOLOGY LETTERS

The Emerging Role of Exosomes in Epithelial–Mesenchymal-Transition in Cancer

(2014) Laura Jayne Vella   Frontiers in Oncology

Exosomes

(2013) Huang-Ge Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Circular RNAs: splicing’s enigma variations

(2013) Matthias W Hentze et al.   EMBO JOURNAL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

(2013) Fei Luo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Blockade of p53 by HIF-2α, but not HIF-1α, is involved in arsenite-induced malignant transformation of human bronchial epithelial cells

(2012) Yuan Xu et al.   ARCHIVES OF TOXICOLOGY

Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation

(2012) Min Ling et al.   FREE RADICAL BIOLOGY AND MEDICINE

The accumulations of HIF-1α and HIF-2α by JNK and ERK are involved in biphasic effects induced by different levels of arsenite in human bronchial epithelial cells

(2012) Yuan Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tumour size measurement in a mouse model using high resolution MRI

(2012) Mikael Montelius et al.   BMC MEDICAL IMAGING

The role of EZH2 in tumour progression

(2011) C-J Chang et al.   BRITISH JOURNAL OF CANCER

Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase

(2010) Priya Aggarwal et al.   CANCER CELL

The polycomb group gene product Ezh2 regulates proliferation and differentiation of murine hepatic stem/progenitor cells

(2010) Ryutaro Aoki et al.   JOURNAL OF HEPATOLOGY

Arsenic-induced cell proliferation is associated with enhanced ROS generation, Erk signaling and CyclinA expression

(2010) Rajdeep Chowdhury et al.   TOXICOLOGY LETTERS

Requirement of Arsenic Biomethylation for Oxidative DNA Damage

(2009) Chikara Kojima et al.   JNCI-Journal of the National Cancer Institute