Small RNA sequencing revealed dysregulated piRNAs in Alzheimer's disease and their probable role in pathogenesis

Diagnostic Value of microRNA for Alzheimer’s Disease: A Systematic Review and Meta-Analysis

(2016) Yong-Bo Hu et al.   Frontiers in Aging Neuroscience

tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription

(2015) A. Molla-Herman et al.   EMBO JOURNAL

piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis

(2015) Wee Siong Sho Goh et al.   GENES & DEVELOPMENT

Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals

(2015) Gung-wei Chirn et al.   PLoS Genetics

Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers

(2015) Giovanni Lugli et al.   PLoS One

RNA sequencing identifies specific PIWI-interacting small non-coding RNA expression patterns in breast cancer

(2015) Adnan Hashim et al.   Oncotarget

Detection of PIWI and piRNAs in the mitochondria of mammalian cancer cells

(2014) ChangHyuk Kwon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Beta-Amyloid Oligomers Activate Apoptotic BAK Pore for Cytochrome c Release

(2014) Jaewook Kim et al.   BIOPHYSICAL JOURNAL

piRNAQuest: searching the piRNAome for silencers

(2014) Arijita Sarkar et al.   BMC GENOMICS

A comprehensive analysis of piRNAs from adult human testis and their relationship with genes and mobile elements

(2014) Hongseok Ha et al.   BMC GENOMICS

The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells

(2014) Simon P. Keam et al.   NUCLEIC ACIDS RESEARCH

Small RNA profiling and characterization of piRNA clusters in the adult testes of the common marmoset, a model primate

(2014) Takamasa Hirano et al.   RNA

A Paired RNAi and RabGAP Overexpression Screen Identifies Rab11 as a Regulator of β-Amyloid Production

(2014) Vinod Udayar et al.   Cell Reports

iMir: An integrated pipeline for high-throughput analysis of small non-coding RNA data obtained by smallRNA-Seq

(2013) Giorgio Giurato et al.   BMC BIOINFORMATICS

A Major Epigenetic Programming Mechanism Guided by piRNAs

(2013) Xiao A. Huang et al.   DEVELOPMENTAL CELL

piRNAs Warrant Investigation in Rett Syndrome: An Omics Perspective

(2013) Alka Saxena et al.   DISEASE MARKERS

Alteration of the microRNA network during the progression of Alzheimer's disease

(2013) Pierre Lau et al.   EMBO Molecular Medicine

Distribution, evolution, and diversity of retrotransposons at the flamenco locus reflect the regulatory properties of piRNA clusters

(2013) V. Zanni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mirTools 2.0 for non-coding RNA discovery, profiling, and functional annotation based on high-throughput sequencing

(2013) Jinyu Wu et al.   RNA Biology

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

A Role for Neuronal piRNAs in the Epigenetic Control of Memory-Related Synaptic Plasticity

(2012) Priyamvada Rajasethupathy et al.   CELL

Structure of yeast Argonaute with guide RNA

(2012) Kotaro Nakanishi et al.   NATURE

Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease

(2011) Eric M. Blalock et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

KPNA6 (Importin  7)-Mediated Nuclear Import of Keap1 Represses the Nrf2-Dependent Antioxidant Response

(2011) Z. Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing

(2011) Michael Reuter et al.   NATURE

Identification of piRNAs in the central nervous system

(2011) E. J. Lee et al.   RNA

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Critical association of ncRNA with introns

(2010) David Rearick et al.   NUCLEIC ACIDS RESEARCH

Joint Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer's Disease Cortex Reveals Altered miRNA Regulation

(2010) Juan Nunez-Iglesias et al.   PLoS One

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Specialized piRNA Pathways Act in Germline and Somatic Tissues of the Drosophila Ovary

(2009) Colin D. Malone et al.   CELL

A Broadly Conserved Pathway Generates 3′UTR-Directed Primary piRNAs

(2009) Nicolas Robine et al.   CURRENT BIOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

(2008) Toshiaki Watanabe et al.   NATURE

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

(2008) Oliver H. Tam et al.   NATURE

A universal classification of eukaryotic transposable elements implemented in Repbase

(2008) Vladimir V. Kapitonov et al.   NATURE REVIEWS GENETICS