The role of microRNAs in neurodegenerative diseases: a review

MicroRNAs in the pathophysiology of Alzheimer’s disease and Parkinson's disease: an overview

(2022) Mohammad Rafi Khezri et al.   MOLECULAR NEUROBIOLOGY

Advances in the development of new biomarkers for Alzheimer’s disease

(2022) Timofey O. Klyucherev et al.   Translational Neurodegeneration

Downregulation of microRNA-15b-5p Targeting the Akt3-Mediated GSK-3β/β-Catenin Signaling Pathway Inhibits Cell Apoptosis in Parkinson’s Disease

(2021) Jianzhong Zhu et al.   Biomed Research International

Eating microRNAs: pharmacological opportunities for cross‐kingdom regulation and implications in host gene and gut microbiota modulation

(2021) Lorena Pozo‐Acebo et al.   BRITISH JOURNAL OF PHARMACOLOGY

MicroRNA-185 activates PI3K/AKT signaling pathway to alleviate dopaminergic neuron damage via targeting IGF1 in Parkinson’s disease

(2021) Xiaocui Qin et al.   JOURNAL OF DRUG TARGETING

The Risks of miRNA Therapeutics: In a Drug Target Perspective

(2021) Song Zhang et al.   Drug Design Development and Therapy

miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors

(2021) Sonali Sharma et al.   BLOOD

MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation

(2021) Vijay Swahari et al.   Cell Reports

Nucleic Acid Delivery for Therapeutic Applications

(2021) Akash Gupta et al.   ADVANCED DRUG DELIVERY REVIEWS

Connection between miRNA Mediation and the Bioactive Effects of Broccoli (Brassica oleracea var. italica): Exogenous miRNA Resistance to Food Processing and GI Digestion

(2021) Luis A. Chapado et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibition of miR-96-5p May Reduce Aβ42/Aβ40 Ratio via Regulating ATP-binding cassette transporter A1

(2021) Min Zhu et al.   JOURNAL OF ALZHEIMERS DISEASE

miR-146a Dysregulates Energy Metabolism During Neuroinflammation

(2021) Sujung Jun Kim et al.   Journal of Neuroimmune Pharmacology

Honeysuckle-derived microRNA2911 inhibits tumor growth by targeting TGF-β1

(2021) Chunyan Liu et al.   Chinese Medicine

The role of microRNA-34 family in Alzheimer’s disease: A potential molecular link between neurodegeneration and metabolic disorders

(2021) Maryam Bazrgar et al.   PHARMACOLOGICAL RESEARCH

Increased miR‐34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS‐JNK‐p53 pathway in Alzheimer’s Disease

(2020) Zhongli Shi et al.   AGING CELL

Ketogenic diets and protective mechanisms in epilepsy, metabolic disorders, cancer, neuronal loss, and muscle and nerve degeneration

(2020) Rui‐Jun Li et al.   JOURNAL OF FOOD BIOCHEMISTRY

miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer’s Disease

(2020) Ana Teresa Barros-Viegas et al.   Molecular Therapy-Nucleic Acids

miR-22 protect PC12 from ischemia/reperfusion-induced injury by targeting p53 upregulated modulator of apoptosis (PUMA)

(2020) Hongmei Jiao et al.   Bioengineered

MiR-211 protects cerebral ischemia/reperfusion injury by inhibiting cell apoptosis

(2020) Wenyi Liu et al.   Bioengineered

Overexpression of MicroRNA-133a Inhibits Apoptosis and Autophagy in a Cell Model of Parkinson’s Disease by Downregulating Ras-Related C3 Botulinum Toxin Substrate 1 (RAC1)

(2020) Wusheng Lu et al.   MEDICAL SCIENCE MONITOR

miR‐30b protects nigrostriatal dopaminergic neurons from MPP(+)‐induced neurotoxicity via SNCA

(2020) Yu‐fei Shen et al.   Brain and Behavior

Circulating Exosomal miRNA as Diagnostic Biomarkers of Neurodegenerative Diseases

(2020) Lin Wang et al.   Frontiers in Molecular Neuroscience

Differential roles of miR‐15a/16‐1 and miR‐497/195 clusters in immune cell development and homeostasis

(2020) Katharina Hutter et al.   FEBS Journal

Competition between maturation and degradation drives human snRNA 3′ end quality control

(2020) Rea M. Lardelli et al.   GENES & DEVELOPMENT

CircRNA 001372 Reduces Inflammation in Propofol-Induced Neuroinflammation and Neural Apoptosis through PIK3CA/Akt/NF-κB by miRNA-148b-3p

(2020) Mingyu Wang et al.   JOURNAL OF INVESTIGATIVE SURGERY

Cognitive Decline and Modulation of Alzheimer’s Disease-Related Genes After Inhibition of MicroRNA-101 in Mouse Hippocampal Neurons

(2020) C. Barbato et al.   MOLECULAR NEUROBIOLOGY

Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients

(2020) Li-Kun Zhou et al.   Cell Discovery

SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs

(2020) Qun Chen et al.   CELL RESEARCH

MiR-455-5p attenuates cerebral ischemic reperfusion injury via targeting FLT3

(2020) Jinjing Chen et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Plant miRNAs Reduce Cancer Cell Proliferation by Targeting MALAT1 and NEAT1: A Beneficial Cross-Kingdom Interaction

(2020) Flaviana Marzano et al.   Frontiers in Genetics

Inhibition of the BCL6/miR-31/PKD1 axis attenuates oxidative stress-induced neuronal damage

(2020) Pingbo Wei et al.   EXPERIMENTAL NEUROLOGY

miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling

(2020) Marcus J. Hines et al.   Cell Reports

MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs

(2020) A. Alwin Prem Anand et al.   Frontiers in Cell and Developmental Biology

MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer

(2019) Lu Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

miR-9: From function to therapeutic potential in cancer

(2019) Mostafa Khafaei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA-132 attenuates cerebral injury by protecting blood-brain-barrier in MCAO mice

(2019) Xiaokun Zuo et al.   EXPERIMENTAL NEUROLOGY

Activation of MT2 receptor ameliorates dendritic abnormalities in Alzheimer’s disease via C/EBPα/miR-125b pathway

(2019) Hui Tang et al.   AGING CELL

miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

(2019) Nan Xu et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

The potential role of miR‐29 in health and cancer diagnosis, prognosis, and therapy

(2019) Mohsen Alizadeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Honeysuckle-derived microRNA2911 directly inhibits varicella-zoster virus replication by targeting IE62 gene

(2019) Ying Huang et al.   JOURNAL OF NEUROVIROLOGY

MiR-34 and MiR-200: Regulator of Cell Fate Plasticity and Neural Development

(2019) Abhishek Jauhari et al.   NEUROMOLECULAR MEDICINE

Antioxidant effects of curcumin in models of neurodegeneration, aging, oxidative and nitrosative stress: A review

(2019) Shameemah Abrahams et al.   NEUROSCIENCE

Plant MIR156 Regulates Intestinal Growth in Mammals by Targeting the Wnt/β-catenin Pathway

(2019) Meng Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Plant-derived RNAi therapeutics: A strategic inhibitor of HBsAg

(2019) Shuo Zhang et al.   BIOMATERIALS

miR-124 upregulates astrocytic glutamate transporter-1 via the Akt and mTOR signaling pathway post ischemic stroke

(2019) Wei-Yi Huang et al.   BRAIN RESEARCH BULLETIN

MicroRNA-101a Regulates Autophagy Phenomenon via the MAPK Pathway to Modulate Alzheimer’s-Associated Pathogenesis

(2019) Qian Li et al.   CELL TRANSPLANTATION

Klotho Ameliorates Cellular Inflammation via Suppression of Cytokine Release and Upregulation of miR-29a in the PBMCs of Diagnosed Alzheimer’s Disease Patients

(2019) Mohsen Sedighi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

miR‑29 promotes the proliferation of cultured rat neural stem/progenitor cells via the PTEN/AKT signaling pathway

(2019) Yunan Gao et al.   Molecular Medicine Reports

Upregulation of miR-34a by Inhibition of IRE1α Has Protective Effect against Aβ-Induced Injury in SH-SY5Y Cells by Targeting Caspase-2

(2019) Qianqian Li et al.   Oxidative Medicine and Cellular Longevity

microRNA dysregulation in neurodegenerative diseases: A systematic review

(2019) Camille A. Juźwik et al.   PROGRESS IN NEUROBIOLOGY

Nuclear Pre-snRNA Export Is an Essential Quality Assurance Mechanism for Functional Spliceosomes

(2019) Daniel Becker et al.   Cell Reports

Long noncoding RNA HAGLROS regulates apoptosis and autophagy in Parkinson’s disease via regulating miR-100/ATG10 axis and PI3K/Akt/mTOR pathway activation

(2019) Tao Peng et al.   Artificial Cells Nanomedicine and Biotechnology

MicroRNA-200a-3p Mediates Neuroprotection in Alzheimer-Related Deficits and Attenuates Amyloid-Beta Overproduction and Tau Hyperphosphorylation via Coregulating BACE1 and PRKACB

(2019) Linlin Wang et al.   Frontiers in Pharmacology

Non-coding RNA regulatory networks

(2019) Simona Panni et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

MiR-410 exerts neuroprotective effects in a cellular model of Parkinson's disease induced by 6-hydroxydopamine via inhibiting the PTEN/AKT/mTOR signaling pathway

(2019) Hanming Ge et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Preliminary study of hsa-miR-626 change in the cerebrospinal fluid of Parkinson’s disease patients

(2019) Li-xia Qin et al.   JOURNAL OF CLINICAL NEUROSCIENCE

The emerging role of the piRNA/piwi complex in cancer

(2019) Yongmei Liu et al.   Molecular Cancer

miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival

(2019) John D. Gagnon et al.   Cell Reports

Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases

(2019) Konovalova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Post-Transcriptional Regulation of Soluble Guanylate Cyclase that Governs Neuropathic Pain in Alzheimer’s Disease

(2019) Heng Xu et al.   JOURNAL OF ALZHEIMERS DISEASE

The temporal and causal relationship between inflammation and neurodegeneration in multiple sclerosis

(2019) Ron Milo et al.   Multiple Sclerosis Journal

Exosomal secretion of a psychosis-altered miRNA that regulates glutamate receptor expression is affected by antipsychotics

(2019) Stephen K. Amoah et al.   NEUROPSYCHOPHARMACOLOGY

Biomarkers for Parkinson’s Disease: How Good Are They?

(2019) Tianbai Li et al.   Neuroscience Bulletin

miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients

(2019) Diana J. Cha et al.   Frontiers in Neuroscience

Plant MIR167e-5p Inhibits Enterocyte Proliferation by Targeting β-Catenin

(2019) Meng Li et al.   Cells

MiR-107 overexpression attenuates neurotoxicity induced by 6-hydroxydopamine both in vitro and in vivo

(2019) Li Sun et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Deciphering miRNAs’ Action through miRNA Editing

(2019) Marta Correia de Sousa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotective effect of crocin against rotenone-induced Parkinson's disease in rats: Interplay between PI3K/Akt/mTOR signaling pathway and enhanced expression of miRNA-7 and miRNA-221

(2019) Rania M. Salama et al.   NEUROPHARMACOLOGY

Honeysuckle-encoded microRNA2911 inhibits Enterovirus 71 replication via targeting VP1 gene

(2018) Xihan Li et al.   ANTIVIRAL RESEARCH

Epigenetic regulation of astrocyte function in neuroinflammation and neurodegeneration

(2018) Matthew Neal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MiR-21 attenuates apoptosis-triggered by amyloid-β via modulating PDCD4/ PI3K/AKT/GSK-3β pathway in SH-SY5Y cells

(2018) Mei-Guo Feng et al.   BIOMEDICINE & PHARMACOTHERAPY

miR-15b Reduces Amyloid-β Accumulation in SH-SY5Y Cell Line through Targeting NF-κB signaling and BACE1

(2018) Juan Li et al.   BIOSCIENCE REPORTS

Study on the inhibition of Mfn1 by plant-derived miR5338 mediating the treatment of BPH with rape bee pollen

(2018) Xuan Chen et al.   BMC Complementary and Alternative Medicine

REST, a master transcriptional regulator in neurodegenerative disease

(2018) Jee-Yeon Hwang et al.   CURRENT OPINION IN NEUROBIOLOGY

The Pax protein Eyegone (Eyg) interacts with the pi-RNA component Aubergine (Aub) and controls egg chamber development in Drosophila

(2018) David Blom-Dahl et al.   DEVELOPMENTAL BIOLOGY

Inhibition of microRNA-505 suppressed MPP+-induced cytotoxicity of SHSY5Y cells in an in vitro Parkinson's disease model

(2018) Jianzhong Zhu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inflammation in CNS neurodegenerative diseases

(2018) Jodie Stephenson et al.   IMMUNOLOGY

Molecular therapy using siRNA: Recent trends and advances of multi target inhibition of cancer growth

(2018) Shweta Jain et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

miRNA 933 Expression by Endothelial Cells is Increased by 27-Hydroxycholesterol and is More Prevalent in Plasma from Dementia Patients

(2018) Irundika H.K. Dias et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of microRNA-10a on synapse remodeling in hippocampal neurons and neuronal cell proliferation and apoptosis through the BDNF-TrkB signaling pathway in a rat model of Alzheimer's disease

(2018) Bo-Wen Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The potential atheroprotective role of plant MIR156a as a repressor of monocyte recruitment on inflamed human endothelial cells

(2018) Dongxia Hou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress

(2018) Ricardo Cabezas et al.   MOLECULAR NEUROBIOLOGY

Regulation of ADAM10 by miR-140-5p and potential relevance for Alzheimer's disease

(2018) Rumana Akhter et al.   NEUROBIOLOGY OF AGING

MiR-181b regulates autophagy in a model of Parkinson’s disease by targeting the PTEN/Akt/mTOR signaling pathway

(2018) Wei Li et al.   NEUROSCIENCE LETTERS

Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models

(2018) Sayuri Higaki et al.   PLoS One

Journey of siRNA: Clinical Developments and Targeted Delivery

(2018) Rahul R. Nikam et al.   Nucleic Acid Therapeutics

Supplemental Treatment for Huntington’s Disease with miR-132 that Is Deficient in Huntington’s Disease Brain

(2018) Masashi Fukuoka et al.   Molecular Therapy-Nucleic Acids

miR-34b/c Regulates Wnt1 and Enhances Mesencephalic Dopaminergic Neuron Differentiation

(2018) Roberto De Gregorio et al.   Stem Cell Reports

Inhibition of MicroRNA-96 Ameliorates Cognitive Impairment and Inactivation Autophagy Following Chronic Cerebral Hypoperfusion in the Rat

(2018) Peifang Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

piRNA-Guided Genome Defense: From Biogenesis to Silencing

(2018) Benjamin Czech et al.   Annual Review of Genetics

The emerging role of microRNA-4487/6845-3p in Alzheimer’s disease pathologies is induced by Aβ25–35 triggered in SH-SY5Y cell

(2018) Ling Hu et al.   BMC Systems Biology

miR-9 Upregulation Integrates Post-ischemic Neuronal Survival and Regeneration In Vitro

(2018) Sreekala S. Nampoothiri et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Down-regulated expression of microRNA-338-5p contributes to neuropathology in Alzheimer’s disease

(2018) Qi Qian et al.   FASEB JOURNAL

Overexpression of microRNA-183 promotes apoptosis of substantia nigra neurons via the inhibition of OSMR in a mouse model of Parkinson's disease

(2018) Jin-Xia Gao et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The Spatiotemporal Expression Pattern of MicroRNA in the Developing Mouse Nervous System

(2018) Pengcheng Shu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology

(2018) Annerieke Sierksma et al.   Molecular Neurodegeneration

Food-Derived Xeno-microRNAs: Influence of Diet and Detectability in Gastrointestinal Tract-Proof-of-Principle Study

(2018) Jastin Link et al.   MOLECULAR NUTRITION & FOOD RESEARCH

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-212-5p Prevents Dopaminergic Neuron Death by Inhibiting SIRT2 in MPTP-Induced Mouse Model of Parkinson’s Disease

(2018) Sifan Sun et al.   Frontiers in Molecular Neuroscience

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Huntington's disease: a clinical review

(2017) P. McColgan et al.   EUROPEAN JOURNAL OF NEUROLOGY

Detection of Plant miRNAs Abundance in Human Breast Milk

(2017) Anna Lukasik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA-142 regulates inflammation and T cell differentiation in an animal model of multiple sclerosis

(2017) Farideh Talebi et al.   Journal of Neuroinflammation

Regulation of miR-34 Family in Neuronal Development

(2017) Abhishek Jauhari et al.   MOLECULAR NEUROBIOLOGY

Targeting the HDAC2/HNF-4A/miR-101b/AMPK Pathway Rescues Tauopathy and Dendritic Abnormalities in Alzheimer’s Disease

(2017) Dan Liu et al.   MOLECULAR THERAPY

Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes

(2017) Wei Qiang et al.   NATURE

Necroptosis activation in Alzheimer's disease

(2017) Antonella Caccamo et al.   NATURE NEUROSCIENCE

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

Downregulation of miR-132/212 impairs S-nitrosylation balance and induces tau phosphorylation in Alzheimer's disease

(2017) Yang Wang et al.   NEUROBIOLOGY OF AGING

Regulatory factor X1 depresses ApoE-dependent Aβ uptake by miRNA-124 in microglial response to oxidative stress

(2017) Chen-Zhuo Feng et al.   NEUROSCIENCE

MicroRNA-144 modulates oxidative stress tolerance in SH-SY5Y cells by regulating nuclear factor erythroid 2-related factor 2-glutathione axis

(2017) Chunlei Zhou et al.   NEUROSCIENCE LETTERS

MicroRNAs: Roles in Regulating Neuroinflammation

(2017) Andrew D. Gaudet et al.   NEUROSCIENTIST

Down-regulation of miR-9* in the peripheral leukocytes of Huntington’s disease patients

(2017) Kuo-Hsuan Chang et al.   Orphanet Journal of Rare Diseases

Dicer and microRNAs protect adult dopamine neurons

(2017) Piotr Chmielarz et al.   Cell Death & Disease

MiR-124-3p attenuates hyperphosphorylation of Tau protein-induced apoptosis via caveolin-1-PI3K/Akt/GSK3β pathway in N2a/APP695swe cells

(2017) Qingmei Kang et al.   Oncotarget

Identification of the Role of miR-142-5p in Alzheimer’s Disease by Comparative Bioinformatics and Cellular Analysis

(2017) Juhyun Song et al.   Frontiers in Molecular Neuroscience

2016 Alzheimer's disease facts and figures

(2016)   Alzheimers & Dementia

miR-106b inhibits tau phosphorylation at Tyr18 by targeting Fyn in a model of Alzheimer's disease

(2016) Wei Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Geniposide reduces α-synuclein by blocking microRNA-21/lysosome-associated membrane protein 2A interaction in Parkinson disease models

(2016) Chunhe Su et al.   BRAIN RESEARCH

Cross-kingdom inhibition of breast cancer growth by plant miR159

(2016) Andrew R Chin et al.   CELL RESEARCH

Genome-wide identification and functional annotation of miRNAs in anti-inflammatory plant and their cross-kingdom regulation in Homo sapiens

(2016) Ankita Sharma et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Immune-mediated processes in neurodegeneration: where do we stand?

(2016) Marc Fakhoury   JOURNAL OF NEUROLOGY

The miR-15/107 Family of microRNA Genes Regulates CDK5R1/p35 with Implications for Alzheimer’s Disease Pathogenesis

(2016) Silvia Moncini et al.   MOLECULAR NEUROBIOLOGY

miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1)

(2016) Jaekwang Kim et al.   Molecular Neurodegeneration

Neurodegenerative diseases

(2016) Marie-Thérèse Heemels   NATURE

Osthole decreases beta amyloid levels through up-regulation of miR-107 in Alzheimer’s disease

(2016) Yanan Jiao et al.   NEUROPHARMACOLOGY

MiRNA-Mediated Macrophage Polarization and its Potential Role in the Regulation of Inflammatory Response

(2016) Kobina Essandoh et al.   SHOCK

Embryonic Development of the Central Nervous System

(2016) Alexander de Lahunta et al.   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration

(2016) Surjyadipta Bhattacharjee et al.   PLoS One

Therapeutic Effects of Transplantation of As-MiR-937-Expressing Mesenchymal Stem Cells in Murine Model of Alzheimer's Disease

(2015) Zhen Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Role of miR-124 in Drosophila Alzheimer's Disease Model by Targeting Delta in Notch Signaling Pathway

(2015) Y. Kong et al.   CURRENT MOLECULAR MEDICINE

MicroRNA-138 promotes tau phosphorylation by targeting retinoic acid receptor alpha

(2015) Xiong Wang et al.   FEBS LETTERS

miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregationin vivo

(2015) Pascal Y. Smith et al.   HUMAN MOLECULAR GENETICS

MicroRNAs in pediatric central nervous system embryonal neoplasms: the known unknown

(2015) Maria Braoudaki et al.   Journal of Hematology & Oncology

MicroRNA-15/16 AntagonizesMybTo Control NK Cell Maturation

(2015) Ryan P. Sullivan et al.   JOURNAL OF IMMUNOLOGY

PDL1 Regulation by p53 via miR-34

(2015) Maria Angelica Cortez et al.   JNCI-Journal of the National Cancer Institute

MicroRNA-29c targets β-site amyloid precursor protein-cleaving enzyme 1 and has a neuroprotective role in vitro and in vivo

(2015) GUOSHUAI YANG et al.   Molecular Medicine Reports

Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice

(2015) Aikaterini S. Papadopoulou et al.   NEUROBIOLOGY OF DISEASE

Overview of MicroRNA Biology

(2015) Ashley Mohr et al.   SEMINARS IN LIVER DISEASE

Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells

(2015) Begum Alural et al.   Frontiers in Cellular Neuroscience

Genome-wide circulating microRNA expression profiling indicates biomarkers for epilepsy

(2015) Jun Wang et al.   Scientific Reports

PDL1 Regulation by p53 via miR-34

(2015) Maria Angelica Cortez et al.   JNCI-Journal of the National Cancer Institute

Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease

(2015) Sepideh Parsi et al.   Molecular Therapy-Nucleic Acids

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

(2014) Oleg Butovsky et al.   ANNALS OF NEUROLOGY

Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses

(2014) Zhen Zhou et al.   CELL RESEARCH

MicroRNA-29c/PTEN Pathway is Involved in Mice Brain Development and Modulates Neurite Outgrowth in PC12 Cells

(2014) Hongjun Zou et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease

(2014) J. Banzhaf-Strathmann et al.   EMBO JOURNAL

Prognostic serum miRNA biomarkers associated with Alzheimer’s disease shows concordance with neuropsychological and neuroimaging assessment

(2014) L Cheng et al.   MOLECULAR PSYCHIATRY

The RNA World: molecular cooperation at the origins of life

(2014) Paul G. Higgs et al.   NATURE REVIEWS GENETICS

miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling

(2014) Woori Kim et al.   NEUROBIOLOGY OF AGING

MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer’s disease

(2014) Z.-B. Zhao et al.   NEUROSCIENCE

Modulation of HBV replication by microRNA-15b through targeting hepatocyte nuclear factor 1α

(2014) Xiaopeng Dai et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs in central nervous system development

(2014) Néstor F. Díaz et al.   REVIEWS IN THE NEUROSCIENCES

Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network

(2014) Jing Fang et al.   Cell Reports

MicroRNA-9 controls dendritic development by targeting REST

(2014) Sebastian A Giusti et al.   eLife

Assessing the survival of exogenous plant microRNA in mice

(2014) GaoFeng Liang et al.   Food Science & Nutrition

The regulation of Hox gene expression during animal development

(2013) Moisés Mallo et al.   DEVELOPMENT

Astrocyte-enriched miR-29a targets PUMA and reduces neuronal vulnerability to forebrain ischemia

(2013) Yi-Bing Ouyang et al.   GLIA

MicroRNA Expression Changes during Interferon-Beta Treatment in the Peripheral Blood of Multiple Sclerosis Patients

(2013) Michael Hecker et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MiR-26b, Upregulated in Alzheimer's Disease, Activates Cell Cycle Entry, Tau-Phosphorylation, and Apoptosis in Postmitotic Neurons

(2013) S. Absalon et al.   JOURNAL OF NEUROSCIENCE

First microRNA mimic enters clinic

(2013) Aaron Bouchie   NATURE BIOTECHNOLOGY

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

New roles for microRNAs in cross-species communication

(2013) Hongwei Liang et al.   RNA Biology

MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain

(2012) Siok-Lay Tan et al.   GENES TO CELLS

MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein

(2012) Hyun Jin Cho et al.   HUMAN MOLECULAR GENETICS

miR-29ab1 Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis

(2012) K. M. Smith et al.   JOURNAL OF IMMUNOLOGY

The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila

(2012) Nan Liu et al.   NATURE

microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons

(2012) Federico Dajas-Bailador et al.   NATURE NEUROSCIENCE

The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC

(2012) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury

(2012) Alison J. Kriegel et al.   PHYSIOLOGICAL GENOMICS

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

miR-29c regulates BACE1 protein expression

(2011) Yuanyuan Zong et al.   BRAIN RESEARCH

MiR-34, SIRT1, and p53: The feedback loop

(2011) Munekazu Yamakuchi et al.   CELL CYCLE

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

(2011) Lin Zhang et al.   CELL RESEARCH

MicroRNA-9 Reveals Regional Diversity of Neural Progenitors along the Anterior-Posterior Axis

(2011) Boyan Bonev et al.   DEVELOPMENTAL CELL

MicroRNA-29 Regulates T-Box Transcription Factors and Interferon-γ Production in Helper T Cells

(2011) David F. Steiner et al.   IMMUNITY

MicroRNA-9 Regulates Neurogenesis in Mouse Telencephalon by Targeting Multiple Transcription Factors

(2011) M. Shibata et al.   JOURNAL OF NEUROSCIENCE

MicroRNA miR-9 Modifies Motor Neuron Columns by a Tuning Regulation of FoxP1 Levels in Developing Spinal Cords

(2011) G. Otaegi et al.   JOURNAL OF NEUROSCIENCE

miR-15 and miR-16 Are Direct Transcriptional Targets of E2F1 that Limit E2F-Induced Proliferation by Targeting Cyclin E

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MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma

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Differential Regulation of Interleukin-1 Receptor-associated Kinase-1 (IRAK-1) and IRAK-2 by MicroRNA-146a and NF-κB in Stressed Human Astroglial Cells and in Alzheimer Disease

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Variation in the miRNA-433 Binding Site of FGF20 Confers Risk for Parkinson Disease by Overexpression of α-Synuclein

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MicroRNA-298 and MicroRNA-328 Regulate Expression of Mouse β-Amyloid Precursor Protein-converting Enzyme 1

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Purkinje-Cell-Restricted Restoration of Kv3.3 Function Restores Complex Spikes and Rescues Motor Coordination in Kcnc3 Mutants

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The Expression of MicroRNA miR-107 Decreases Early in Alzheimer's Disease and May Accelerate Disease Progression through Regulation of  -Site Amyloid Precursor Protein-Cleaving Enzyme 1

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