Strategies to inhibit arsenic trioxide-induced cardiotoxicity in acute promyelocytic leukemia

Long-Term Oral Administration of Theaphenon-E Improves Cardiomyocyte Mechanics and Calcium Dynamics by Affecting Phospholamban Phosphorylation and ATP Production

(2018) Leonardo Bocchi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cardioprotective effect of paeonol against epirubicin-induced heart injury via regulating miR-1 and PI3K/AKT pathway

(2018) Jing Wu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Eugenol, a plant-derived phenolic nutraceutical, protects thiol (SH) group in myocardium from ROS-mediated oxidation under chemotherapeutic stress induced by arsenic trioxide – a in vivo model study

(2018) P. Binu et al.   DRUG AND CHEMICAL TOXICOLOGY

Strategies to increase cardioprotection through cardioprotective chemokines in chemotherapy-induced cardiotoxicity

(2018) Habib Haybar et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Exosomal miR-21a-5p mediates cardioprotection by mesenchymal stem cells

(2018) Kristin M. Luther et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

L-ascorbic acid and α-tocopherol attenuate arsenic trioxide-induced toxicity in H9c2 cardiomyocytes by the activation of Nrf2 and Bcl2 transcription factors

(2018) Radhakrishnan Chandraprabha Vineetha et al.   TOXICOLOGY MECHANISMS AND METHODS

L-ascorbic acid and α-tocopherol attenuate arsenic trioxide-induced toxicity in H9c2 cardiomyocytes by the activation of Nrf2 and Bcl2 transcription factors

(2018) Radhakrishnan Chandraprabha Vineetha et al.   TOXICOLOGY MECHANISMS AND METHODS

Salvianolic Acid A Ameliorates Arsenic Trioxide-Induced Cardiotoxicity Through Decreasing Cardiac Mitochondrial Injury and Promotes Its Anticancer Activity

(2018) Jing-yi Zhang et al.   Frontiers in Pharmacology

Development of Selective, Orally Active GPR4 Antagonists with Modulatory Effects on Nociception, Inflammation, and Angiogenesis

(2017) Juraj Velcicky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Natural products modulating the hERG channel: heartaches and hope

(2017) Jadel M. Kratz et al.   NATURAL PRODUCT REPORTS

Calcium homeostasis and endoplasmic reticulum stress are involved in Salvianolic acid B-offered protection against cardiac toxicity of arsenic trioxide

(2017) Jing-Yi Zhang et al.   Oncotarget

HMGB1 promotes differentiation syndrome by inducing hyperinflammation via MEK/ERK signaling in acute promyelocytic leukemia cells

(2017) Lanlan Tang et al.   Oncotarget

Fibroblast growth factor-2-mediated protection of cardiomyocytes from the toxic effects of doxorubicin requires the mTOR/Nrf-2/HO-1 pathway

(2017) Navid Koleini et al.   Oncotarget

Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity

(2017) Maria Abad et al.   Stem Cell Reports

Omega-3 Fatty Acid Protects Against Arsenic Trioxide-Induced Cardiotoxicity In Vitro and In Vivo

(2016) Mathews V. Varghese et al.   Cardiovascular Toxicology

Lipid emulsion reverses bupivacaine-induced apoptosis of h9c2 cardiomyocytes: PI3K/Akt/GSK-3β signaling pathway

(2016) Danni Lv et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Targeting peroxiredoxin I potentiates 1,25-dihydroxyvitamin D3-induced cell differentiation in leukemia cells

(2016) WEI WEI et al.   Molecular Medicine Reports

Baicalein inhibits TNF-α-induced NF-κB activation and expression of NF-κB-regulated target gene products

(2016) Junbo Li et al.   ONCOLOGY REPORTS

Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity

(2016) J Wu et al.   Cell Death & Disease

High-mobility group box 1-mediated heat shock protein beta 1 expression attenuates mitochondrial dysfunction and apoptosis

(2015) Taro Narumi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardioprotection mechanism of mangiferin on doxorubicin-induced rats: Focus on intracellular calcium regulation

(2015) Femmi Dwinda Agustini et al.   PHARMACEUTICAL BIOLOGY

Identification of H7 as a novel peroxiredoxin I inhibitor to induce differentiation of leukemia cells

(2015) Wei Wei et al.   Oncotarget

Up-regulation of miR-21 and miR-23a Contributes to As2O3-induced hERG Channel Deficiency

(2014) Xin Zhao et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Notch affects the prodifferentiating effect of retinoic acid and PMA on leukemic cells

(2014) Maja Matulic et al.   CYTOMETRY PART A

Involvement of miR-1 in the protective effect of hydrogen sulfide against cardiomyocyte apoptosis induced by ischemia/reperfusion

(2014) Bo Kang et al.   MOLECULAR BIOLOGY REPORTS

Genistein Ameliorates Adverse Cardiac Effects Induced by Arsenic Trioxide Through Preventing Cardiomyocytes Apoptosis

(2013) Yuhua Fan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy

(2013) Xavier Palomer et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Metallothionein prevention of arsenic trioxide-induced cardiac cell death is associated with its inhibition of mitogen-activated protein kinases activation in vitro and in vivo

(2013) Xiao Miao et al.   TOXICOLOGY LETTERS

2-Deoxy-d-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: Involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways

(2012) María Cristina Estañ et al.   BIOCHEMICAL PHARMACOLOGY

Arsenic trioxide prevents nitric oxide production in lipopolysaccharide -stimulated RAW 264.7 by inhibiting a TRIF-dependent pathway

(2012) Miyuki Takahashi et al.   CANCER SCIENCE

Regulation of C/EBPβ and resulting functions in cells of the monocytic lineage

(2012) René Huber et al.   CELLULAR SIGNALLING

Resveratrol attenuates hepatotoxicity of rats exposed to arsenic trioxide

(2012) Weiqian Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

Upregulation of microRNA-1 and microRNA-133 contributes to arsenic-induced cardiac electrical remodeling

(2012) Hongli Shan et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Effect of ginsenoside Rh1 on myocardial injury and heart function in isoproterenol-induced cardiotoxicity in rats

(2012) Yusheng Gai et al.   TOXICOLOGY MECHANISMS AND METHODS

Absence of SOCS3 in the Cardiomyocyte Increases Mortality in a gp130-Dependent Manner Accompanied by Contractile Dysfunction and Ventricular Arrhythmias

(2011) Toshitaka Yajima et al.   CIRCULATION

Peroxiredoxins are involved in metallothionein protection from doxorubicin cardiotoxicity

(2011) Li Jing et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MicroRNAs and cardiovascular diseases

(2011) Koh Ono et al.   FEBS Journal

PI3K/Akt signaling pathway involved in cardioprotection of preconditioning with high mobility group box 1 protein during myocardial ischemia and reperfusion

(2011) Xiaorong Hu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The histone deacetylase inhibitor butyroyloxymethyl diethylphosphate (AN-7) protects normal cells against toxicity of anticancer agents while augmenting their anticancer activity

(2010) Nataly Tarasenko et al.   INVESTIGATIONAL NEW DRUGS

Transient activation ofc-MYCexpression is critical for efficient platelet generation from human induced pluripotent stem cells

(2010) Naoya Takayama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of the mitochondrial permeability transition pore in heart disease

(2009) Andrew P. Halestrap et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A Novel Role of MicroRNA in Late Preconditioning

(2009) Chang Yin et al.   CIRCULATION RESEARCH

Typical 2-Cys peroxiredoxins - structures, mechanisms and functions

(2009) Andrea Hall et al.   FEBS Journal

Mitochondrial oxidative stress and dysfunction in myocardial remodelling

(2008) H. Tsutsui et al.   CARDIOVASCULAR RESEARCH

The effects of short term statin treatment on left ventricular function and inflammatory markers in patients with chronic heart failure

(2007) Cemil Gürgün et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY