Nutraceuticals in HIV and COVID-19-Related Neurological Complications: Opportunity to Use Extracellular Vesicles as Drug Delivery Modality

Neuroinvasion of SARS-CoV-2 in human and mouse brain

(2021) Eric Song et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Spatial and Cell-Type Distribution of SARS-CoV-2 Receptor ACE2 in the Human and Mouse Brains

(2021) Rongrong Chen et al.   Frontiers in Neurology

Coincubation as miR-Loading Strategy to Improve the Anti-Tumor Effect of Stem Cell-Derived EVs

(2021) Alessia Brossa et al.   Pharmaceutics

Bell’s palsy following COVID-19 vaccination

(2021) Giuseppe Colella et al.   JOURNAL OF NEUROLOGY

Coronavirus-Induced Host Cubic Membranes and Lipid-Related Antiviral Therapies: A Focus on Bioactive Plasmalogens

(2021) Yuru Deng et al.   Frontiers in Cell and Developmental Biology

Nanotechnology approaches for global infectious diseases

(2021) Ameya R. Kirtane et al.   Nature Nanotechnology

Epidemiology and outcomes of COVID-19 in HIV-infected individuals: a systematic review and meta-analysis

(2021) Paddy Ssentongo et al.   Scientific Reports

Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening

(2021) Yuan Xiong et al.   FITOTERAPIA

A human chorionic gonadotropin (hCG) delivery platform using engineered uterine exosomes to improve endometrial receptivity

(2021) Hamed Hajipour et al.   LIFE SCIENCES

Nutraceuticals in Immune Function

(2021) Soo-Liang Ooi et al.   MOLECULES

Extracellular vesicles as a next-generation drug delivery platform

(2021) Inge Katrin Herrmann et al.   Nature Nanotechnology

Covid-19 Breakthrough Infections in Vaccinated Health Care Workers

(2021) Moriah Bergwerk et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-HIV Activity of Cucurbitacin-D against Cigarette Smoke Condensate-Induced HIV Replication in the U1 Macrophages

(2021) Sunitha Kodidela et al.   Viruses-Basel

Nutraceuticals in Viral Infections: An Overview of the Immunomodulating Properties

(2021) Giorgio Costagliola et al.   Nutrients

Nutraceutical Approach to Preventing Coronavirus Disease 2019 and Related Complications

(2021) Giuseppe Derosa et al.   Frontiers in Immunology

Development of Extracellular Vesicle Therapeutics: Challenges, Considerations, and Opportunities

(2021) Bethany Claridge et al.   Frontiers in Cell and Developmental Biology

The Relationship Between Vitamin D and Infections Including COVID-19: Any Hopes?

(2021) Rbab Taha et al.   International Journal of General Medicine

A review of natural products, their effects on SARS-CoV-2 and their utility as lead compounds in the discovery of drugs for the treatment of COVID-19

(2021) Robert L. Chapman et al.   MEDICINAL CHEMISTRY RESEARCH

Link between serum lipid signature and prognostic factors in COVID-19 patients

(2021) Michele Dei Cas et al.   Scientific Reports

Role of Extracellular Vesicles in Cell Death and Inflammation

(2021) Rahul Sanwlani et al.   Cells

Active cargo loading into extracellular vesicles: Highlights the heterogeneous encapsulation behaviour

(2021) Chaoxiang Chen et al.   Journal of Extracellular Vesicles

Dietary supplements and nutraceuticals market growth during the coronavirus pandemic – Implications for consumers and regulatory oversight

(2021) Ronan Lordan   PharmaNutrition

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China

(2020) David S. Hui et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study

(2020) Joseph T Wu et al.   LANCET

Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus

(2020) Mark F. McCarty et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Extracellular Vesicles from Human Papilloma Virus-Infected Cervical Cancer Cells Enhance HIV-1 Replication in Differentiated U1 Cell Line

(2020) Sabina Ranjit et al.   Viruses-Basel

Interactions between antiretroviral therapy and complementary and alternative medicine: a narrative review

(2020) C. Bordes et al.   CLINICAL MICROBIOLOGY AND INFECTION

A first case of meningitis/encephalitis associated with SARS-Coronavirus-2

(2020) Takeshi Moriguchi et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Potential Use of Extracellular Vesicles Generated by Microbubble-Assisted Ultrasound as Drug Nanocarriers for Cancer Treatment

(2020) Yuana Yuana et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stilbene-based natural compounds as promising drug candidates against COVID-19

(2020) Hussain Mustatab Wahedi et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Angiotensin‐converting enzyme‐2 ( ACE2 ), SARS‐CoV ‐2 and pathophysiology of coronavirus disease 2019 ( COVID ‐19)

(2020) Arno R. Bourgonje et al.   JOURNAL OF PATHOLOGY

Neurologic manifestations in hospitalized patients with COVID-19: The ALBACOVID registry

(2020) Carlos Manuel Romero-Sánchez et al.   NEUROLOGY

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Considerations for Obesity, Vitamin D, and Physical Activity Amid the COVID‐19 Pandemic

(2020) Stephen J. Carter et al.   Obesity

Potential effects of curcumin in the treatment of COVID ‐19 infection

(2020) Fatemeh Zahedipour et al.   PHYTOTHERAPY RESEARCH

Differential packaging of inflammatory cytokines/ chemokines and oxidative stress modulators in U937 and U1 macrophages-derived extracellular vesicles upon exposure to tobacco constituents

(2020) Sanjana Haque et al.   PLoS One

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repurposing Antiviral Protease Inhibitors Using Extracellular Vesicles for Potential Therapy of COVID-19

(2020) Santosh Kumar et al.   Viruses-Basel

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths

(2020) William B. Grant et al.   Nutrients

Ginkgolic acid inhibits fusion of enveloped viruses

(2020) Ronen Borenstein et al.   Scientific Reports

COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics

(2020) Kuldeep Dhama et al.   Human Vaccines & Immunotherapeutics

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

(2020) Ling Mao et al.   JAMA Neurology

COVID-19 in patients with HIV: clinical case series

(2020) Jose L Blanco et al.   Lancet HIV

Extracellular Vesicles in Smoking-Mediated HIV Pathogenesis and their Potential Role in Biomarker Discovery and Therapeutic Interventions

(2020) Sanjana Haque et al.   Cells

Circulatory Astrocyte and Neuronal EVs as Potential Biomarkers of Neurological Dysfunction in HIV-Infected Subjects and Alcohol/Tobacco Users

(2020) Sunitha Kodidela et al.   Diagnostics

Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro

(2020) Ka-Tim Choy et al.   ANTIVIRAL RESEARCH

Neurological manifestations in COVID-19 infection: A systematic review and meta-analysis

(2020) Maria Epifania V. Collantes et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Neurological manifestations of COVID-19 and other coronavirus infections: A systematic review

(2020) V. Montalvan et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Clinical Outcomes and Immunologic Characteristics of Coronavirus Disease 2019 in People With Human Immunodeficiency Virus

(2020) Hsi-en Ho et al.   JOURNAL OF INFECTIOUS DISEASES

HIV/SARS‐CoV‐2 coinfection: A global perspective

(2020) Osman N. Kanwugu et al.   JOURNAL OF MEDICAL VIROLOGY

A prospective clinical study of detailed neurological manifestations in patients with COVID-19

(2020) Ömer Karadaş et al.   NEUROLOGICAL SCIENCES

COVID-19 may induce Guillain–Barré syndrome

(2020) J.-P. Camdessanche et al.   REVUE NEUROLOGIQUE

Extracellular Vesicles in Viral Replication and Pathogenesis and Their Potential Role in Therapeutic Intervention

(2020) Asit Kumar et al.   Viruses-Basel

Patterns of HIV and SARS‐CoV‐2 co‐infection in Wuhan, China

(2020) Wei Guo et al.   Journal of the International AIDS Society

Quercetin and Vitamin C: An Experimental, Synergistic Therapy for the Prevention and Treatment of SARS-CoV-2 Related Disease (COVID-19)

(2020) Ruben Manuel Luciano Colunga Biancatelli et al.   Frontiers in Immunology

SARS ‐CoV‐2 targets neurons of 3D human brain organoids

(2020) Anand Ramani et al.   EMBO JOURNAL

Traditional Herbal Medicine for the Prevention and Treatment of Cold and Flu in the Autumn of 2020, Overlapped With COVID-19

(2020) Mohamad Hesam Shahrajabian et al.   Natural Product Communications

Therapeutic potential of resveratrol against emerging respiratory viral infections

(2020) Simone Filardo et al.   PHARMACOLOGY & THERAPEUTICS

A Single Large Dose of Vitamin D Could be Used as a Means of Coronavirus Disease 2019 Prevention and Treatment

(2020) Guoqiang Liu et al.   Drug Design Development and Therapy

Frequent neurologic manifestations and encephalopathy‐associated morbidity in Covid‐19 patients

(2020) Eric M. Liotta et al.   Annals of Clinical and Translational Neurology

Extracellular Vesicle-Based Nucleic Acid Delivery: Current Advances and Future Perspectives in Cancer Therapeutic Strategies

(2020) Crescenzo Massaro et al.   Pharmaceutics

Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment

(2020) Wenxi Zhou et al.   BIOMATERIALS

Challenges in Biomaterial-Based Drug Delivery Approach for the Treatment of Neurodegenerative Diseases: Opportunities for Extracellular Vesicles

(2020) Asit Kumar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators

(2020) Benjamin Schwarz et al.   JOURNAL OF IMMUNOLOGY

Curcumin-laden exosomes target ischemic brain tissue and alleviate cerebral ischemia-reperfusion injury by inhibiting ROS-mediated mitochondrial apoptosis

(2020) Ruyi He et al.   Materials Science & Engineering C-Materials for Biological Applications

Neprilysin expression and functions in development, ageing and disease

(2020) NN Nalivaeva et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Role of Vitamin C, Vitamin D, and Selenium in Immune System against COVID-19

(2020) Minkyung Bae et al.   MOLECULES

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Neurological manifestations associated with SARS-CoV-2 and other coronaviruses: A narrative review for clinicians

(2020) A. Maury et al.   REVUE NEUROLOGIQUE

COvid-19 and high-dose VITamin D supplementation TRIAL in high-risk older patients (COVIT-TRIAL): study protocol for a randomized controlled trial

(2020) Cédric Annweiler et al.   Trials

Vitamin C—An Adjunctive Therapy for Respiratory Infection, Sepsis and COVID-19

(2020) Patrick Holford et al.   Nutrients

Micronutrients and bioactive substances: Their potential roles in combating COVID-19

(2020) Tibebeselassie Seyoum Keflie et al.   NUTRITION

Improved loading of plasma derived-extracellular vesicles to encapsulate antitumor miRNAs

(2019) Margherita Alba Carlotta Pomatto et al.   Molecular Therapy-Methods & Clinical Development

Exosome-transmitted miR-128-3p increase chemosensitivity of oxaliplatin-resistant colorectal cancer

(2019) Tong Liu et al.   Molecular Cancer

Proteomic Profiling of Exosomes Derived from Plasma of HIV-Infected Alcohol Drinkers and Cigarette Smokers

(2019) Sunitha Kodidela et al.   Journal of Neuroimmune Pharmacology

Extracellular Vesicles: Intercellular Mediators in Alcohol-Induced Pathologies

(2019) Mohammad A. Rahman et al.   Journal of Neuroimmune Pharmacology

TPP1 Delivery to Lysosomes with Extracellular Vesicles and their Enhanced Brain Distribution in the Animal Model of Batten Disease

(2019) Matthew J. Haney et al.   Advanced Healthcare Materials

Nanotechnology approaches for delivery of cytochrome P450 substrates in HIV treatment

(2019) Yuqing Gong et al.   Expert Opinion on Drug Delivery

Study on the Mechanism of Curcumin Regulating Lung Injury Induced by Outdoor Fine Particulate Matter (PM2.5)

(2019) Kunlun Huang et al.   MEDIATORS OF INFLAMMATION

Extracellular Vesicles: A Possible Link between HIV and Alzheimer’s Disease-Like Pathology in HIV Subjects?

(2019) Sunitha Kodidela et al.   Cells

Macrophage-Derived Extracellular Vesicles as Drug Delivery Systems for Triple Negative Breast Cancer (TNBC) Therapy

(2019) Matthew J. Haney et al.   Journal of Neuroimmune Pharmacology

Cytochalasin-B-Inducible Nanovesicle Mimics of Natural Extracellular Vesicles That Are Capable of Nucleic Acid Transfer

(2019) Oshchepkova et al.   Micromachines

Gemcitabine loaded autologous exosomes for effective and safe chemotherapy of pancreatic cancer

(2019) Yong-Jiang Li et al.   Acta Biomaterialia

Circulating Extracellular Vesicles Containing Xenobiotic Metabolizing CYP Enzymes and Their Potential Roles in Extrahepatic Cells Via Cell–Cell Interactions

(2019) Kelli Gerth et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aspirin-loaded nanoexosomes as cancer therapeutics

(2019) Phuong H.L. Tran et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

(2019) Zhaogang Yang et al.   Nature Biomedical Engineering

Modification of Extracellular Vesicles by Fusion with Liposomes for the Design of Personalized Biogenic Drug Delivery Systems

(2018) Max Piffoux et al.   ACS Nano

Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

(2018) Tian Tian et al.   BIOMATERIALS

Engineering macrophage-derived exosomes for targeted paclitaxel delivery to pulmonary metastases: in vitro and in vivo evaluations

(2018) Myung Soo Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Bioprocess Decision Support Tool For Scalable Manufacture of Extracellular Vesicles

(2018) Kelvin S. Ng et al.   BIOTECHNOLOGY AND BIOENGINEERING

Exosomes produced from three-dimensional cultures of mesenchymal stem cells by tangential flow filtration show higher yield and improved activity

(2018) Reka Agnes Haraszti et al.   MOLECULAR THERAPY

Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle

(2018) Hosna Gomari et al.   OncoTargets and Therapy

Benzo(a)pyrene in Cigarette Smoke Enhances HIV-1 Replication through NF-κB Activation via CYP-Mediated Oxidative Stress Pathway

(2018) Sabina Ranjit et al.   Scientific Reports

Vitamin D Toxicity–A Clinical Perspective

(2018) Ewa Marcinowska-Suchowierska et al.   Frontiers in Endocrinology

Bioactivity, Health Benefits, and Related Molecular Mechanisms of Curcumin: Current Progress, Challenges, and Perspectives

(2018) Xiao-Yu Xu et al.   Nutrients

Antioxidant activities of novel resveratrol analogs in breast cancer

(2017) Anwesha Chatterjee et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors

(2017) Ji-Young Park et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment

(2017) Christian Eggers et al.   JOURNAL OF NEUROLOGY

Herbal Medications in Cardiovascular Medicine

(2017) Rosa Liperoti et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

SVCT2 Expression and Function in Reactive Astrocytes Is a Common Event in Different Brain Pathologies

(2017) Katterine Salazar et al.   MOLECULAR NEUROBIOLOGY

Efficacy of vitamin D3 supplementation in reducing incidence of pulmonary tuberculosis and mortality among HIV-infected Tanzanian adults initiating antiretroviral therapy: study protocol for a randomized controlled trial

(2017) Christopher R. Sudfeld et al.   Trials

Effect of maternal vitamin D3 supplementation on maternal health, birth outcomes, and infant growth among HIV-infected Tanzanian pregnant women: study protocol for a randomized controlled trial

(2017) Christopher R. Sudfeld et al.   Trials

Exosomal delivery of berry anthocyanidins for the management of ovarian cancer

(2017) Farrukh Aqil et al.   Food & Function

Vitamin C and Infections

(2017) Harri Hemilä   Nutrients

4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol} (TIMBD) suppresses HIV1-gp120 mediated production of IL6 and IL8 but not CCL5

(2017) Fatma Abdalla et al.   Scientific Reports

Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo Chronic Myelogenous Leukemia cell growth

(2017) Daniele Bellavia et al.   Theranostics

Progress in Exosome Isolation Techniques

(2017) Pin Li et al.   Theranostics

Extracellular vesicles for drug delivery

(2016) Pieter Vader et al.   ADVANCED DRUG DELIVERY REVIEWS

Oncogene Knockdown via Active Loading of Small RNAs into Extracellular Vesicles by Sonication

(2016) Tek N. Lamichhane et al.   Cellular and Molecular Bioengineering

Resveratrol as a Potential Therapeutic Candidate for the Treatment and Management of Alzheimer';s Disease

(2016) Nady Braidy et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Exosomal formulation enhances therapeutic response of celastrol against lung cancer

(2016) Farrukh Aqil et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing

(2016) Marie-Cécile Didiot et al.   MOLECULAR THERAPY

Exosomes increase the therapeutic index of doxorubicin in breast and ovarian cancer mouse models

(2016) Mohamad Hadla et al.   Nanomedicine

Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells

(2016) Myung Soo Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment

(2016) Deanna Saylor et al.   Nature Reviews Neurology

Ginkgolic Acid Protects against Aβ-Induced Synaptic Dysfunction in the Hippocampus

(2016) Dalila Mango et al.   Frontiers in Pharmacology

Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer’s disease

(2015) K. G. Goozee et al.   BRITISH JOURNAL OF NUTRITION

Herbal Medicine for Anxiety, Depression and Insomnia

(2015) Lei Liu et al.   Current Neuropharmacology

Exosomes as drug delivery vehicles for Parkinson's disease therapy

(2015) Matthew J. Haney et al.   JOURNAL OF CONTROLLED RELEASE

Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins

(2015) Gregor Fuhrmann et al.   JOURNAL OF CONTROLLED RELEASE

Curcumin improves synaptic plasticity impairment induced by HIV-1gp120 V3 loop

(2015) Ying Xu et al.   Neural Regeneration Research

Curcumin Increases HSP70 Expression in Primary Rat Cortical Neuronal Apoptosis Induced by gp120 V3 Loop Peptide

(2015) Chenglai Xia et al.   NEUROCHEMICAL RESEARCH

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

Curcumin and its analogues: a potential natural compound against HIV infection and AIDS

(2015) Sahdeo Prasad et al.   Food & Function

Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder

(2015) Pasquale Mansueto et al.   Biomed Research International

Dehydroascorbic Acid Attenuates Ischemic Brain Edema and Neurotoxicity in Cerebral Ischemia: Anin vivoStudy

(2015) Juhyun Song et al.   Experimental Neurobiology

Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

(2014) Adriaan H. de Wilde et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficient extraction strategies of tea (Camellia sinensis) biomolecules

(2014) Satarupa Banerjee et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes

(2014) Christina Schiborr et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline

(2014) I. Grant et al.   NEUROLOGY

Life Expectancy of Persons Receiving Combination Antiretroviral Therapy in Low-Income Countries: A Cohort Analysis From Uganda

(2013) Edward J. Mills et al.   ANNALS OF INTERNAL MEDICINE

Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth

(2013) Mark Katakowski et al.   CANCER LETTERS

HIV-associated neurocognitive disorder

(2013) David B Clifford et al.   LANCET INFECTIOUS DISEASES

Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro

(2013) Jian-Ming Lü et al.   MEDICAL SCIENCE MONITOR

Curcumin Protects Microglia and Primary Rat Cortical Neurons against HIV-1 gp120-Mediated Inflammation and Apoptosis

(2013) Luyan Guo et al.   PLoS One

Functions of plasmalogen lipids in health and disease

(2012) Nancy E. Braverman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sirtuin activators and inhibitors

(2012) José M. Villalba et al.   BIOFACTORS

Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13

(2012) Mi-Sun Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel Aza-resveratrol analogs: Synthesis, characterization and anticancer activity against breast cancer cell lines

(2012) Areej Siddiqui et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Extracellular vesicles in physiological and pathological conditions

(2012) Yuana Yuana et al.   BLOOD REVIEWS

Over-expression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis

(2012) Boris Sabirzhanov et al.   JOURNAL OF NEUROCHEMISTRY

Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway

(2012) Samir Nath et al.   JOURNAL OF NEUROVIROLOGY

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

(2012) Shin-ichiro Ohno et al.   MOLECULAR THERAPY

Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

(2012) John M Ringman et al.   Alzheimers Research & Therapy

Extracellular HIV-1 Tat upregulates TNF-α dependent MCP-1/CCL2 production via activation of ERK1/2 pathway in rat hippocampal slice cultures: Inhibition by resveratrol, a polyphenolic phytostilbene

(2011) Eun Ok Lee et al.   EXPERIMENTAL NEUROLOGY

Analysis of serum and supplemented vitamin C and oxidative stress in HIV-infected children and adolescents

(2011) Karoline Faria de Oliveira et al.   Jornal de Pediatria

Competitive Interactions of Cancer Cells and Normal Cells via Secretory MicroRNAs

(2011) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Protective Role of Heat Shock Proteins in Parkinson’s Disease

(2011) Paolo Aridon et al.   Neurodegenerative Diseases

Nanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease

(2010) Adam Smith et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

(2010) Dongmei Sun et al.   MOLECULAR THERAPY

Green Tea (-)-Epigallocatechin-3-Gallate Inhibits β-Amyloid-Induced Cognitive Dysfunction through Modification of Secretase Activity via Inhibition of ERK and NF-κB Pathways in Mice

(2009) Jae Woong Lee et al.   JOURNAL OF NUTRITION

Pharmacokinetics of Curcumin Conjugate Metabolites in Healthy Human Subjects

(2008) S. K. Vareed et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Angiotensin-converting enzyme 2 in the brain: properties and future directions

(2008) Huijing Xia et al.   JOURNAL OF NEUROCHEMISTRY

Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies

(2008)   LANCET

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY