Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Proteomic and Metabolomic Characterization of COVID-19 Patient Sera

(2020) Bo Shen et al.   CELL

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Non-steroidal anti-inflammatory drugs and covid-19

(2020) Paul Little   BMJ-British Medical Journal

Plasma Metabolomic and Lipidomic Alterations Associated with COVID-19

(2020) Di Wu et al.   National Science Review

Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis

(2020) Jin-Wen Song et al.   Cell Metabolism

Biomarkers of Platelet Activity and Vascular Health Associate with Thrombosis and Mortality in Patients with COVID-19

(2020) Tessa J Barrett et al.   CIRCULATION RESEARCH

A single-cell atlas of the peripheral immune response in patients with severe COVID-19

(2020) Aaron J. Wilk et al.   NATURE MEDICINE

The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism

(2020) H. Blasco et al.   Scientific Reports

Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A2γ in Phospholipid Remodeling

(2019) Patricia Lebrero et al.   Cells

Identification and Profiling of Specialized Pro-Resolving Mediators in Human Tears by Lipid Mediator Metabolomics

(2017) Justin T. English et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Prostaglandin E2 As a Modulator of Viral Infections

(2017) Willem J. Sander et al.   Frontiers in Physiology

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein

(2015) Christoph Lehmann et al.   FASEB JOURNAL

A pH and solvent optimized reverse-phase ion-paring-LC–MS/MS method that leverages multiple scan-types for targeted absolute quantification of intracellular metabolites

(2015) Douglas McCloskey et al.   Metabolomics

Proinflammatory High-Density Lipoprotein Results from Oxidized Lipid Mediators in the Pathogenesis of Both Idiopathic and Associated Types of Pulmonary Arterial Hypertension

(2015) David J. Ross et al.   Pulmonary Circulation

Human Plasma Lipidome Is Pleiotropically Associated With Cardiovascular Risk Factors and Death

(2014) C. Bellis et al.   Circulation-Cardiovascular Genetics

Phospholipase A2 regulates eicosanoid class switching during inflammasome activation

(2014) P. C. Norris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation

(2013) Vincent C. Tam et al.   CELL

Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

(2013) Matthew Spite et al.   Cell Metabolism

Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation

(2013) A. Neuhofer et al.   DIABETES

A comparison of five lipid extraction solvent systems for lipidomic studies of human LDL

(2013) Ana Reis et al.   JOURNAL OF LIPID RESEARCH

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

(2013) Tim Lämmermann et al.   NATURE

Functions of plasmalogen lipids in health and disease

(2012) Nancy E. Braverman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators

(2012) J. Dalli et al.   BLOOD

Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention

(2011) Edward A. Dennis et al.   CHEMICAL REVIEWS

Regulation of Immune Responses by Prostaglandin E2

(2011) P. Kalinski   JOURNAL OF IMMUNOLOGY

Tissue Distribution and Gender-Divergent Expression of 78 Cytochrome P450 mRNAs in Mice

(2011) Helen J. Renaud et al.   TOXICOLOGICAL SCIENCES