COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019‐nCoV

(2020) Jared S. Morse et al.   CHEMBIOCHEM

Recent discovery and development of inhibitors targeting coronaviruses

(2020) Thanigaimalai Pillaiyar et al.   DRUG DISCOVERY TODAY

Preparedness and proactive infection control measures against the emerging novel coronavirus in China

(2020) V.C.C. Cheng et al.   JOURNAL OF HOSPITAL INFECTION

Potential interventions for novel coronavirus in China: A systematic review

(2020) Lei Zhang et al.   JOURNAL OF MEDICAL VIROLOGY

Cross‐species transmission of the newly identified coronavirus 2019‐nCoV

(2020) Wei Ji et al.   JOURNAL OF MEDICAL VIROLOGY

Immunoinformatics‐aided identification of T cell and B cell epitopes in the surface glycoprotein of 2019‐nCoV

(2020) Vargab Baruah et al.   JOURNAL OF MEDICAL VIROLOGY

A novel coronavirus outbreak of global health concern

(2020) Chen Wang et al.   LANCET

Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China

(2020) Fei Yu et al.   MICROBES AND INFECTION

This scientist hopes to test coronavirus drugs on animals in locked-down Wuhan

(2020) David Cyranoski   NATURE

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

(2020) Guangdi Li et al.   NATURE REVIEWS DRUG DISCOVERY

New coronavirus threat galvanizes scientists

(2020) Jon Cohen   SCIENCE

Emerging novel coronavirus (2019-nCoV)—current scenario, evolutionary perspective based on genome analysis and recent developments

(2020) Yashpal Singh Malik et al.   VETERINARY QUARTERLY

Characterization of novel monoclonal antibodies against MERS-coronavirus spike protein

(2020) Junghyun Goo et al.   VIRUS RESEARCH

Characterization of the Immune Response of MERS-CoV Vaccine Candidates Derived from Two Different Vectors in Mice

(2020) Entao Li et al.   Viruses-Basel

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

(2020) Timothy P. Sheahan et al.   Nature Communications

An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies

(2020) Shibo Jiang et al.   Emerging Microbes & Infections

Drug treatment options for the 2019-new coronavirus (2019-nCoV)

(2020) Hongzhou Lu   BioScience Trends

Superior immune responses induced by intranasal immunization with recombinant adenovirus-based vaccine expressing full-length Spike protein of Middle East respiratory syndrome coronavirus

(2019) Myung Hee Kim et al.   PLoS One

Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus

(2019) Chean Yeah Yong et al.   Frontiers in Microbiology

Identification of the immunodominant neutralizing regions in the spike glycoprotein of porcine deltacoronavirus

(2019) Rui Chen et al.   VIRUS RESEARCH

Combination attenuation offers strategy for live-attenuated coronavirus vaccines

(2018) Vineet D. Menachery et al.   JOURNAL OF VIROLOGY

Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial

(2018) Yaseen M. Arabi et al.   Trials

Human transbodies that interfere with the functions of Ebola virus VP35 protein in genome replication and transcription and innate immune antagonism

(2018) Watee Seesuay et al.   Emerging Microbes & Infections

Prospects for a MERS-CoV spike vaccine

(2018) Yusen Zhou et al.   Expert Review of Vaccines

Advances in Designing and Developing Vaccines, Drugs, and Therapies to Counter Ebola Virus

(2018) Kuldeep Dhama et al.   Frontiers in Immunology

Analysis of the genome sequence and prediction of B-cell epitopes of the envelope protein of Middle East respiratory syndrome-coronavirus

(2017) Qian Xie et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Entry of Human Coronavirus NL63 into the Cell

(2017) Aleksandra Milewska et al.   JOURNAL OF VIROLOGY

Cross-neutralization of SARS coronavirus-specific antibodies against bat SARS-like coronaviruses

(2017) Lei-Ping Zeng et al.   Science China-Life Sciences

Advances in Developing Therapies to Combat Zika Virus: Current Knowledge and Future Perspectives

(2017) Ashok Munjal et al.   Frontiers in Microbiology

Vaccines for the prevention against the threat of MERS-CoV

(2016) Lanying Du et al.   Expert Review of Vaccines

Coronaviruses — drug discovery and therapeutic options

(2016) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

(2016) Adam S. Cockrell et al.   Nature Microbiology

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

(2015) Jasper Fuk-Woo Chan et al.   JOURNAL OF INFECTIOUS DISEASES

Animal models for SARS and MERS coronaviruses

(2015) Lisa M Gretebeck et al.   Current Opinion in Virology

Epitope-Based Vaccine Target Screening against Highly Pathogenic MERS-CoV: An In Silico Approach Applied to Emerging Infectious Diseases

(2015) Jiandong Shi et al.   PLoS One

Rapid generation of a mouse model for Middle East respiratory syndrome

(2014) Jincun Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infection with MERS-CoV Causes Lethal Pneumonia in the Common Marmoset

(2014) Darryl Falzarano et al.   PLoS Pathogens

Cell-based antiviral screening against coronaviruses: Developing virus-specific and broad-spectrum inhibitors

(2013) Andy Kilianski et al.   ANTIVIRAL RESEARCH

Anti-SARS coronavirus agents: a patent review (2008 – present)

(2013) Vathan Kumar et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Novel Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Entry That Act by Three Distinct Mechanisms

(2013) A. O. Adedeji et al.   JOURNAL OF VIROLOGY

Middle East respiratory syndrome coronavirus (MERS-CoV): challenges in identifying its source and controlling its spread

(2013) Lu Lu et al.   MICROBES AND INFECTION

Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV–infected rhesus macaques

(2013) Darryl Falzarano et al.   NATURE MEDICINE

A decade after SARS: strategies for controlling emerging coronaviruses

(2013) Rachel L. Graham et al.   NATURE REVIEWS MICROBIOLOGY

Pneumonia from Human Coronavirus in a Macaque Model

(2013) Vincent J. Munster et al.   NEW ENGLAND JOURNAL OF MEDICINE

The spike protein of SARS-CoV — a target for vaccine and therapeutic development

(2009) Lanying Du et al.   NATURE REVIEWS MICROBIOLOGY

A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters

(2008) E. W. Lamirande et al.   JOURNAL OF VIROLOGY

Animal models and vaccines for SARS-CoV infection

(2007) Anjeanette Roberts et al.   VIRUS RESEARCH