Nanotechnology approaches for delivery of cytochrome P450 substrates in HIV treatment

Pharmacokinetics and pharmacodynamics of cytochrome P450 inhibitors for HIV treatment

(2019) Yuqing Gong et al.   Expert Opinion on Drug Metabolism & Toxicology

Nanoparticle-in-microparticle oral drug delivery system of a clinically relevant darunavir/ritonavir antiretroviral combination

(2018) Robin Augustine et al.   Acta Biomaterialia

Improving maraviroc oral bioavailability by formation of solid drug nanoparticles

(2018) Alison C. Savage et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Applications of nanoparticle systems in drug delivery technology

(2018) Syed A.A. Rizvi et al.   SAUDI PHARMACEUTICAL JOURNAL

Creation of a long-acting nanoformulated dolutegravir

(2018) Brady Sillman et al.   Nature Communications

Progress and challenges towards targeted delivery of cancer therapeutics

(2018) Daniel Rosenblum et al.   Nature Communications

Enhanced oral bioavailability and brain uptake of Darunavir using lipid nanoemulsion formulation

(2018) Jagruti Desai et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Inhibition of human cytochromes P450 in vitro by ritonavir and cobicistat

(2017) Md Amin Hossain et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial

(2017) David A Margolis et al.   LANCET

Pharmacokinetic and Tissue Distribution Profile of Long Acting Tenofovir Alafenamide and Elvitegravir Loaded Nanoparticles in Humanized Mice Model

(2017) Pavan Kumar Prathipati et al.   PHARMACEUTICAL RESEARCH

Cellulose Acetate Phthalate and Antiretroviral Nanoparticle Fabrications for HIV Pre-Exposure Prophylaxis

(2017) Subhra Mandal et al.   Polymers

Formulation and characterization of solid lipid nanoparticles for an anti-retroviral drug darunavir

(2017) Mangesh Bhalekar et al.   Applied Nanoscience

Getting into the brain: Potential of nanotechnology in the management of NeuroAIDS

(2016) Madhavan Nair et al.   ADVANCED DRUG DELIVERY REVIEWS

Comparative Clinical Pharmacokinetics and Pharmacodynamics of HIV-1 Integrase Strand Transfer Inhibitors

(2016) Anthony T. Podany et al.   CLINICAL PHARMACOKINETICS

Systematic development of solid self-nanoemulsifying oily formulations (S-SNEOFs) for enhancing the oral bioavailability and intestinal lymphatic uptake of lopinavir

(2016) Babita Garg et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Bioavailability enhancement, Caco-2 cells uptake and intestinal transport of orally administered lopinavir-loaded PLGA nanoparticles

(2016) Garima Joshi et al.   DRUG DELIVERY

Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS

(2016) Arun K. Ghosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Effect of particle size on oral bioavailability of darunavir-loaded solid lipid nanoparticles

(2016) Jagruti Desai et al.   JOURNAL OF MICROENCAPSULATION

Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials

(2016) Joseph M. Caster et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Strategies to target non-T-cell HIV reservoirs

(2016) Jonah B. Sacha et al.   Current Opinion in HIV and AIDS

Enhancement of cellular uptake, transport and oral absorption of protease inhibitor saquinavir by nanocrystal formulation

(2015) Yuan He et al.   ACTA PHARMACOLOGICA SINICA

Thermosensitive Gel Containing Cellulose Acetate Phthalate-Efavirenz Combination Nanoparticles for Prevention of HIV-1 Infection

(2015) Abhijit A. Date et al.   Journal of Biomedical Nanotechnology

Nanoparticle-Based ARV Drug Combinations for Synergistic Inhibition of Cell-Free and Cell–Cell HIV Transmission

(2015) Yonghou Jiang et al.   MOLECULAR PHARMACEUTICS

The potential of HIV-1 nanotherapeutics: fromin vitrostudies to clinical trials

(2015) Upal Roy et al.   Nanomedicine

Fabrication and in vivo evaluation of Nelfinavir loaded PLGA nanoparticles for enhancing oral bioavailability and therapeutic effect

(2015) D. Nagasamy Venkatesh et al.   SAUDI PHARMACEUTICAL JOURNAL

Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission

(2015) Martina Kovarova et al.   PLoS Pathogens

Modified pullulan nanoparticles for oral delivery of lopinavir: Formulation and pharmacokinetic evaluation

(2014) Punna Rao Ravi et al.   CARBOHYDRATE POLYMERS

Development of HIV Reservoir Targeted Long Acting Nanoformulated Antiretroviral Therapies

(2014) Benson Edagwa et al.   CURRENT MEDICINAL CHEMISTRY

Caged protein nanoparticles for drug delivery

(2014) Nicholas M Molino et al.   CURRENT OPINION IN BIOTECHNOLOGY

Atazanavir-loaded Eudragit RL 100 nanoparticles to improve oral bioavailability: optimization andin vitro/in vivoappraisal

(2014) Gurinder Singh et al.   DRUG DELIVERY

A cure for HIV: is it in sight?

(2014) Matthew Pace et al.   Expert Review of Anti-Infective Therapy

Pharmacokinetics, Safety, and Tolerability With Repeat Doses of GSK1265744 and Rilpivirine (TMC278) Long-Acting Nanosuspensions in Healthy Adults

(2014) William Spreen et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

A hybrid design to optimize preparation of lopinavir loaded solid lipid nanoparticles and comparative pharmacokinetic evaluation with marketed lopinavir/ritonavir coformulation

(2014) Punna Rao Ravi et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Metabolism, Excretion, and Mass Balance of the HIV-1 Integrase Inhibitor Dolutegravir in Humans

(2013) Stephen Castellino et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Development and evaluation of glyceryl behenate based solid lipid nanoparticles (SLNs) using hot self-nanoemulsification (SNE) technique

(2013) Jeetendra Singh Negi et al.   ARCHIVES OF PHARMACAL RESEARCH

Design, optimization and evaluation of poly-ɛ-caprolactone (PCL) based polymeric nanoparticles for oral delivery of lopinavir

(2013) Punna Rao Ravi et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Darunavir: A Review of Its Use in the Management of HIV-1 Infection

(2013) Emma D. Deeks   DRUGS

Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients

(2013) Jennifer Williams et al.   Nanomedicine

Drug Synergy of Tenofovir and Nanoparticle-Based Antiretrovirals for HIV Prophylaxis

(2013) Thanyanan Chaowanachan et al.   PLoS One

The utility of self-emulsifying oil formulation to improve the poor solubility of the anti HIV drug CSIC

(2013) Nicholas C Obitte et al.   AIDS Research and Therapy

Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice

(2012) Prasanta K. Dash et al.   AIDS

Rilpivirine: A second-generation nonnucleoside reverse transcriptase inhibitor

(2012) C. James et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Design of polymeric nanoparticles for biomedical delivery applications

(2012) Mahmoud Elsabahy et al.   CHEMICAL SOCIETY REVIEWS

Development of solid lipid nanoparticles (SLNs) of lopinavir using hot self nano-emulsification (SNE) technique

(2012) Jeetendra Singh Negi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier

(2012) Ana Beloqui et al.   JOURNAL OF CONTROLLED RELEASE

Nanotechnology and the Treatment of HIV Infection

(2012) Raveen Parboosing et al.   Viruses-Basel

Clinical Pharmacokinetic and Pharmacodynamic Profile of the HIV Integrase Inhibitor Elvitegravir

(2011) Srinivasan Ramanathan et al.   CLINICAL PHARMACOKINETICS

Methylmethacrylate–sulfopropylmethacrylate nanoparticles with surface RMP-7 for targeting delivery of antiretroviral drugs across the blood–brain barrier

(2011) Yung-Chih Kuo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

In Silico, In Vitro and In Situ Models to Assess Interplay Between CYP3A and P-gp

(2011) Daniel R. Mudra et al.   CURRENT DRUG METABOLISM

Complex Drug Interactions of HIV Protease Inhibitors 1: Inactivation, Induction, and Inhibition of Cytochrome P450 3A by Ritonavir or Nelfinavir

(2011) B. J. Kirby et al.   DRUG METABOLISM AND DISPOSITION

Surface modified nevirapine nanosuspensions for viral reservoir targeting: In vitro and in vivo evaluation

(2011) Ranjita Shegokar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Solid lipid nanoparticles and nanosuspension formulation of Saquinavir: preparation, characterization, pharmacokinetics and biodistribution studies

(2011) Shamsunder S. Dodiya et al.   JOURNAL OF MICROENCAPSULATION

Targeting nevirapine delivery across human brain microvascular endothelial cells using transferrin-grafted poly(lactide-co-glycolide) nanoparticles

(2011) Yung-Chih Kuo et al.   Nanomedicine

Antiretroviral Therapy as HIV Prevention: Status and Prospects

(2010) Kenneth H. Mayer et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Pharmacokinetics and Disposition of Rilpivirine (TMC278) Nanosuspension as a Long-Acting Injectable Antiretroviral Formulation

(2010) G. van 't Klooster et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antiretroviral release from poly(DL-lactide-co-glycolide) nanoparticles in mice

(2010) C. J. Destache et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages

(2010) Ari S. Nowacek et al.   JOURNAL OF CONTROLLED RELEASE

Combination antiretroviral drugs in PLGA nanoparticle for HIV-1

(2009) Christopher J Destache et al.   BMC INFECTIOUS DISEASES

Clinically Significant Adverse Events from a Drug Interaction Between Quetiapine and Atazanavir-Ritonavir in Two Patients

(2009) Todd M Pollack et al.   PHARMACOTHERAPY

Assessment of the absorption, metabolism and absolute bioavailability of maraviroc in healthy male subjects

(2008) Samantha Abel et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Solid Lipid Nanoparticles Enhance the Delivery of the HIV Protease Inhibitor, Atazanavir, by a Human Brain Endothelial Cell Line

(2008) Niladri Chattopadhyay et al.   PHARMACEUTICAL RESEARCH

Improved oral bioavailability and brain transport of Saquinavir upon administration in novel nanoemulsion formulations

(2007) Tushar K. Vyas et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Electromagnetic interference in the permeability of saquinavir across the blood–brain barrier using nanoparticulate carriers

(2007) Y KUO et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS