Curcumin-laden exosomes target ischemic brain tissue and alleviate cerebral ischemia-reperfusion injury by inhibiting ROS-mediated mitochondrial apoptosis
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Curcumin-laden exosomes target ischemic brain tissue and alleviate cerebral ischemia-reperfusion injury by inhibiting ROS-mediated mitochondrial apoptosis
Authors
Keywords
Ischemia-reperfusion injury, Oxidative stress, Blood-brain barrier, Reactive oxygen species, Curcumin, Exosomes
Journal
Materials Science & Engineering C-Materials for Biological Applications
Volume 117, Issue -, Pages 111314
Publisher
Elsevier BV
Online
2020-08-05
DOI
10.1016/j.msec.2020.111314
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Design, synthesis and biological evaluation of chalcone analogues with novel dual antioxidant mechanisms as potential anti-ischemic stroke agents
- (2019) Jiabing Wang et al. Acta Pharmaceutica Sinica B
- Golden Exosomes Selectively Target Brain Pathologies in Neurodegenerative and Neurodevelopmental Disorders
- (2019) Nisim Perets et al. NANO LETTERS
- Exosomes from human urine‐derived stem cells enhanced neurogenesis via miR‐26a/HDAC6 axis after ischaemic stroke
- (2019) Xiaozheng Ling et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Simultaneous Blood–Brain Barrier Crossing and Protection for Stroke Treatment Based on Edaravone-Loaded Ceria Nanoparticles
- (2018) Qunqun Bao et al. ACS Nano
- Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy
- (2018) Tian Tian et al. BIOMATERIALS
- Isoquercetin attenuates oxidative stress and neuronal apoptosis after ischemia/reperfusion injury via Nrf2-mediated inhibition of the NOX4/ROS/NF-κB pathway
- (2018) Yunyi Dai et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Protective Effects of Curcumin Against Ischemia-Reperfusion Injury in the Nervous System
- (2018) Kowsar Bavarsad et al. MOLECULAR NEUROBIOLOGY
- Engineering macrophage-derived exosomes for targeted paclitaxel delivery to pulmonary metastases: in vitro and in vivo evaluations
- (2018) Myung Soo Kim et al. Nanomedicine-Nanotechnology Biology and Medicine
- Shedding light on the cell biology of extracellular vesicles
- (2018) Guillaume van Niel et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Curcumin protects neural cells against ischemic injury in N2a cells and mouse brain with ischemic stroke
- (2018) Cai-Jun Xie et al. Brain and Behavior
- Dopamine-loaded blood exosomes targeted to brain for better treatment of Parkinson's disease
- (2018) Mengke Qu et al. JOURNAL OF CONTROLLED RELEASE
- Angioedema and Hemorrhage After 4.5-Hour tPA (Tissue-Type Plasminogen Activator) Thrombolysis Ameliorated by T541 via Restoring Brain Microvascular Integrity
- (2018) Qing-Fang Chen et al. STROKE
- Physical and Chemical Stability of Curcumin in Aqueous Solutions and Emulsions: Impact of pH, Temperature, and Molecular Environment
- (2017) Mahesh Kharat et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Curcumin prevents reperfusion injury following ischemic stroke in rats via inhibition of NF-κB, ICAM-1, MMP-9 and caspase-3 expression
- (2017) Wei Li et al. Molecular Medicine Reports
- Curcumin Protects against Ischemic Stroke by Titrating Microglia/Macrophage Polarization
- (2017) Zongjian Liu et al. Frontiers in Aging Neuroscience
- Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis
- (2016) Wenbin Liao et al. BIOMATERIALS
- Elucidation of Exosome Migration Across the Blood–Brain Barrier Model In Vitro
- (2016) Claire C. Chen et al. Cellular and Molecular Bioengineering
- Curcumin-loaded embryonic stem cell exosomes restored neurovascular unit following ischemia-reperfusion injury
- (2016) Anuradha Kalani et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
- (2016) Mayank Goyal et al. LANCET
- Curcumin by down-regulating NF-kB and elevating Nrf2, reduces brain edema and neurological dysfunction after cerebral I/R
- (2016) Wei Li et al. MICROVASCULAR RESEARCH
- Extracellular vesicles round off communication in the nervous system
- (2016) Vivian Budnik et al. NATURE REVIEWS NEUROSCIENCE
- Zinc contributes to acute cerebral ischemia-induced blood–brain barrier disruption
- (2016) Zhifeng Qi et al. NEUROBIOLOGY OF DISEASE
- Blood−brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury
- (2015) Roshini Prakash et al. CURRENT OPINION IN NEUROLOGY
- Exosomes as drug delivery vehicles for Parkinson's disease therapy
- (2015) Matthew J. Haney et al. JOURNAL OF CONTROLLED RELEASE
- Using exosomes, naturally-equipped nanocarriers, for drug delivery
- (2015) Elena V. Batrakova et al. JOURNAL OF CONTROLLED RELEASE
- Attenuation of acute stroke injury in rat brain by minocycline promotes blood–brain barrier remodeling and alternative microglia/macrophage activation during recovery
- (2015) Yirong Yang et al. Journal of Neuroinflammation
- Emergent intracranial surgical embolectomy in conjunction with carotid endarterectomy for acute internal carotid artery terminus embolic occlusion and tandem occlusion of the cervical carotid artery due to plaque rupture
- (2015) Hirotaka Hasegawa et al. JOURNAL OF NEUROSURGERY
- Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments
- (2015) Paul M. George et al. NEURON
- Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species
- (2015) Serena Rubina Baglio et al. Stem Cell Research & Therapy
- Exosomes Derived from Mesenchymal Stem Cells
- (2014) Bo Yu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Curcumin-primed exosomes mitigate endothelial cell dysfunction during hyperhomocysteinemia
- (2014) A. Kalani et al. LIFE SCIENCES
- Stroke
- (2014) Brian Owens NATURE
- 4.5-Hour Time Window for Intravenous Thrombolysis With Recombinant Tissue-Type Plasminogen Activator Is Established Firmly
- (2014) Peter D. Schellinger et al. STROKE
- Nanotechnology for neurodegenerative disorders
- (2012) Francesca Re et al. MATURITAS
- Systematic Review of Outcome After Ischemic Stroke Due to Anterior Circulation Occlusion Treated With Intravenous, Intra-Arterial, or Combined Intravenous+Intra-Arterial Thrombolysis
- (2012) Michael T. Mullen et al. STROKE
- Timeliness of Tissue-Type Plasminogen Activator Therapy in Acute Ischemic Stroke
- (2011) Gregg C. Fonarow et al. CIRCULATION
- Triggers of Ischemic Stroke
- (2010) Vincent Guiraud et al. STROKE
- Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kappaB modulation in MES23.5 cells
- (2009) Jun Wang et al. BIOCHEMICAL PHARMACOLOGY
- Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke
- (2008) Wenlan Liu et al. JOURNAL OF NEUROCHEMISTRY
- Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia
- (2008) Wenlan Liu et al. JOURNAL OF NEUROCHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now