Anti-HIV Activity of Cucurbitacin-D against Cigarette Smoke Condensate-Induced HIV Replication in the U1 Macrophages

Novel elvitegravir nanoformulation for drug delivery across the blood-brain barrier to achieve HIV-1 suppression in the CNS macrophages

(2020) Yuqing Gong et al.   Scientific Reports

Novel Mechanistic Insight into the Anticancer Activity of Cucurbitacin D against Pancreatic Cancer (Cuc D Attenuates Pancreatic Cancer)

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Differential packaging of inflammatory cytokines/ chemokines and oxidative stress modulators in U937 and U1 macrophages-derived extracellular vesicles upon exposure to tobacco constituents

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Asymptomatic neurocognitive impairment is a risk for symptomatic decline in a large HIV Canadian cohort study

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Clinical effects of curcumin in enhancing cancer therapy: A systematic review

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HIV replication is associated to inflammasomes activation, IL-1β, IL-18 and caspase-1 expression in GALT and peripheral blood

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The Problem of Curcumin and Its Bioavailability: Could Its Gastrointestinal Influence Contribute to Its Overall Health-Enhancing Effects?

(2018) Adrian L Lopresti   Advances in Nutrition

In-vitro blood–brain barrier modeling: A review of modern and fast-advancing technologies

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Cytokine profiling of exosomes derived from the plasma of HIV-infected alcohol drinkers and cigarette smokers

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Benzo(a)pyrene in Cigarette Smoke Enhances HIV-1 Replication through NF-κB Activation via CYP-Mediated Oxidative Stress Pathway

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Immunomodulatory effects of cigarette smoke condensate in mouse macrophage cell line

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Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication

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Lung Cancer Mortality Associated With Smoking and Smoking Cessation Among People Living With HIV in the United States

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Solving the Blood-Brain Barrier Challenge for the Effective Treatment of HIV Replication in the Central Nervous System

(2016) Luc Bertrand et al.   CURRENT PHARMACEUTICAL DESIGN

Relationship Between HIV Coinfection, Interleukin 10 Production, andMycobacterium tuberculosisin Human Lymph Node Granulomas

(2016) Collin R. Diedrich et al.   JOURNAL OF INFECTIOUS DISEASES

Cytokines and T-Cell Homeostasis in HIV Infection

(2016) Michael L. Freeman et al.   JOURNAL OF INFECTIOUS DISEASES

Effects of Cigarette Smoke Condensate on Oxidative Stress, Apoptotic Cell Death, and HIV Replication in Human Monocytic Cells

(2016) PSS Rao et al.   PLoS One

Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity

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Drugs of abuse and blood-brain barrier endothelial dysfunction: A focus on the role of oxidative stress

(2015) Ravi K Sajja et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells

(2015) Jin Mo Ku et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study

(2015) Ned Sacktor et al.   NEUROLOGY

Curcumin and its analogues: a potential natural compound against HIV infection and AIDS

(2015) Sahdeo Prasad et al.   Food & Function

Effect of Mild-to-Moderate Smoking on Viral Load, Cytokines, Oxidative Stress, and Cytochrome P450 Enzymes in HIV-Infected Individuals

(2015) Anusha Ande et al.   PLoS One

Impact of HIV co-infection on plasma level of cytokines and chemokines of pulmonary tuberculosis patients

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Monocytes Mediate HIV Neuropathogenesis: Mechanisms that Contribute to HIV Associated Neurocognitive Disorders

(2014) Dionna Williams et al.   CURRENT HIV RESEARCH

The good, the bad, and the ugly of interleukin-6 signaling

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HIV-1 Infection Induces Interleukin-1β Production via TLR8 Protein-dependent and NLRP3 Inflammasome Mechanisms in Human Monocytes

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Natural Products; Pharmacological Importance of Family Cucurbitaceae: A Brief Review

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IL-6 in Inflammation, Immunity, and Disease

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Cucurbitacin D is a new inflammasome activator in macrophages

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HIV-associated neurocognitive disorder

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Cytokine production and dysregulation in HIV pathogenesis: Lessons for development of therapeutics and vaccines

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Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis

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Antiretroviral neurotoxicity

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Cucurbitacin D induces growth inhibition, cell cycle arrest, and apoptosis in human endometrial and ovarian cancer cells

(2012) Terukazu Ishii et al.   TUMOR BIOLOGY

The pro- and anti-inflammatory properties of the cytokine interleukin-6

(2011) Jürgen Scheller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Enhanced HIV-1 replication in ex vivo ectocervical tissues from post-menopausal women correlates with increased inflammatory responses

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Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer

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HIV‐1 Viral Escape in Cerebrospinal Fluid of Subjects on Suppressive Antiretroviral Treatment

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Programmed death-1–induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

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Anti-HIV activity of natural triterpenoids and hemisynthetic derivatives 2004–2009

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Darunavir Concentrations in Cerebrospinal Fluid and Blood in HIV-1–Infected Individuals

(2009) Aylin Yilmaz et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The transport of anti-HIV drugs across blood–CNS interfaces: Summary of current knowledge and recommendations for further research

(2009) Lavanya Varatharajan et al.   ANTIVIRAL RESEARCH

Tobacco smoke: A critical etiological factor for vascular impairment at the blood–brain barrier

(2009) M. Hossain et al.   BRAIN RESEARCH

Targeting anti-HIV drugs to the CNS

(2009) Kavitha S Rao et al.   Expert Opinion on Drug Delivery

Cucurbitacin D isolated from Trichosanthes kirilowii induces apoptosis in human hepatocellular carcinoma cells in vitro

(2009) Norito Takahashi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Human Immunodeficiency Virus Infection Alters Tumor Necrosis Factor Alpha Production via Toll-Like Receptor-Dependent Pathways in Alveolar Macrophages and U1 Cells

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