Dissecting Tumor Growth: The Role of Cancer Stem Cells in Drug Resistance and Recurrence
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dissecting Tumor Growth: The Role of Cancer Stem Cells in Drug Resistance and Recurrence
Authors
Keywords
-
Journal
Cancers
Volume 14, Issue 4, Pages 976
Publisher
MDPI AG
Online
2022-02-16
DOI
10.3390/cancers14040976
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The role of hypoxia in the tumor microenvironment and development of cancer stem cell: a novel approach to developing treatment
- (2021) Asieh Emami Nejad et al. Cancer Cell International
- Inflammation-Driven Breast Tumor Cell Plasticity: Stemness/EMT, Therapy Resistance and Dormancy
- (2021) Tamir Baram et al. Frontiers in Oncology
- Acquisition of cancer stem cell capacities after spontaneous cell fusion
- (2021) Candice Merle et al. BMC CANCER
- Cancer stem cells and macrophages: molecular connections and future perspectives against cancer
- (2021) Beatrice Aramini et al. Oncotarget
- Current Approaches for Glioma Gene Therapy and Virotherapy
- (2021) Kaushik Banerjee et al. Frontiers in Molecular Neuroscience
- Delivery of gefitinib with an immunostimulatory nanocarrier improves therapeutic efficacy in lung cancer
- (2021) Dingwei Diao et al. Translational Lung Cancer Research
- Chemokines orchestrate tumor cells and the microenvironment to achieve metastatic heterogeneity
- (2021) Sugandha Saxena et al. CANCER AND METASTASIS REVIEWS
- Humanized Mouse Models for the Advancement of Innate Lymphoid Cell-Based Cancer Immunotherapies
- (2021) Nina B. Horowitz et al. Frontiers in Immunology
- Mechanisms of Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation
- (2021) Chelsea Schiliro et al. Cells
- New Perspectives in Different Gene Expression Profiles for Early and Locally Advanced Non-Small Cell Lung Cancer Stem Cells
- (2021) Valentina Masciale et al. Frontiers in Oncology
- Regulation of Formation, Stemness and Therapeutic Resistance of Cancer Stem Cells
- (2021) Nan Jing et al. Frontiers in Cell and Developmental Biology
- The Role of Notch, Hedgehog, and Wnt Signaling Pathways in the Resistance of Tumors to Anticancer Therapies
- (2021) Vivek Kumar et al. Frontiers in Cell and Developmental Biology
- The Role of Tumor-Stroma Interactions in Drug Resistance Within Tumor Microenvironment
- (2021) Yanghong Ni et al. Frontiers in Cell and Developmental Biology
- Cancer cell metabolism connects epigenetic modifications to transcriptional regulation
- (2021) Ashby J. Morrison FEBS Journal
- The metabolic flexibility of quiescent CSC: implications for chemotherapy resistance
- (2021) Kangchen Chen et al. Cell Death & Disease
- Current understanding of epigenetics mechanism as a novel target in reducing cancer stem cells resistance
- (2021) Saeedeh Keyvani-Ghamsari et al. Clinical Epigenetics
- Aspects of the Tumor Microenvironment Involved in Immune Resistance and Drug Resistance
- (2021) Khalil Khalaf et al. Frontiers in Immunology
- Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells
- (2021) Karolin Walter et al. Cancers
- Linking Tumor Microenvironment to Plasticity of Cancer Stem Cells: Mechanisms and Application in Cancer Therapy
- (2021) Xiaobo Zheng et al. Frontiers in Oncology
- Precision Medicine in Oncology: A Review of Multi-Tumor Actionable Molecular Targets with an Emphasis on Non-Small Cell Lung Cancer
- (2021) Matthew K. Stein et al. Journal of Personalized Medicine
- Chronic pain patients’ need for recognition and their current struggle
- (2021) D. Koesling et al. Medicine Health Care and Philosophy
- Mircrining the injured heart with stem cell-derived exosomes: an emerging strategy of cell-free therapy
- (2020) Khawaja Husnain Haider et al. Stem Cell Research & Therapy
- Cancer stem-neuroendocrine cells in an atypical carcinoid case report
- (2020) Valentina Masciale et al. Translational Lung Cancer Research
- The force awakens: metastatic dormant cancer cells
- (2020) So-Yeon Park et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Humanization of Tumor Stroma by Tissue Engineering as a Tool to Improve Squamous Cell Carcinoma Xenograft
- (2020) Sara Guerrero-Aspizua et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Influence of Innate Immunity on Cancer Cell Stemness
- (2020) Anna Pastò et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CD44+/EPCAM+ cells detect a subpopulation of ALDHhigh cells in human non-small cell lung cancer: A chance for targeting cancer stem cells?
- (2020) Valentina Masciale et al. Oncotarget
- Molecular Chaperones in Cancer Stem Cells: Determinants of Stemness and Potential Targets for Antitumor Therapy
- (2020) Alexander Kabakov et al. Cells
- Cell Reversal From a Differentiated to a Stem-Like State at Cancer Initiation
- (2020) João Carvalho Frontiers in Oncology
- Horizontal Gene Transfer: From Evolutionary Flexibility to Disease Progression
- (2020) Melissa Emamalipour et al. Frontiers in Cell and Developmental Biology
- Epithelial–Mesenchymal Transition Programs and Cancer Stem Cell Phenotypes: Mediators of Breast Cancer Therapy Resistance
- (2020) Alex J. Gooding et al. MOLECULAR CANCER RESEARCH
- Cancer Stem Cells—Origins and Biomarkers: Perspectives for Targeted Personalized Therapies
- (2020) Lia Walcher et al. Frontiers in Immunology
- CSC Radioresistance: A Therapeutic Challenge to Improve Radiotherapy Effectiveness in Cancer
- (2020) María Auxiliadora Olivares-Urbano et al. Cells
- Cancer Stem Cells, Quo Vadis? The Notch Signaling Pathway in Tumor Initiation and Progression
- (2020) Christian T. Meisel et al. Cells
- Metabolic Adaptations in Cancer Stem Cells
- (2020) Umesh Prasad Yadav et al. Frontiers in Oncology
- Defining lung cancer stem cells exosomal payload of miRNAs in clinical perspective
- (2020) Beatrice Aramini et al. World Journal of Stem Cells
- Cancer Stem Cell Plasticity – A Deadly Deal
- (2020) Archana P. Thankamony et al. Frontiers in Molecular Biosciences
- The role of microenvironment in tumor angiogenesis
- (2020) Xianjie Jiang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Arming Mesenchymal Stromal/Stem Cells Against Cancer: Has the Time Come?
- (2020) Giulia Golinelli et al. Frontiers in Pharmacology
- Tuning Cancer Fate: Tumor Microenvironment's Role in Cancer Stem Cell Quiescence and Reawakening
- (2020) Antonella Sistigu et al. Frontiers in Immunology
- Recent advances in drug delivery systems for targeting cancer stem cells
- (2020) Hongxia Duan et al. Acta Pharmaceutica Sinica B
- The Metabolic Heterogeneity and Flexibility of Cancer Stem Cells
- (2020) Atsushi Tanabe et al. Cancers
- Therapeutic Targeting of Signaling Pathways Related to Cancer Stemness
- (2020) Asunción Espinosa-Sánchez et al. Frontiers in Oncology
- The lingering mysteries of metastatic recurrence in breast cancer
- (2020) Alessandra I. Riggio et al. BRITISH JOURNAL OF CANCER
- Targeting the Wnt/β-catenin signaling pathway in cancer
- (2020) Ya Zhang et al. Journal of Hematology & Oncology
- Cell–cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness
- (2020) Lucile Delespaul et al. Scientific Reports
- Differences and similarities between cancer and somatic stem cells: therapeutic implications
- (2020) Fiorella Rossi et al. Stem Cell Research & Therapy
- Impact of the Tumor Microenvironment on Tumor Heterogeneity and Consequences for Cancer Cell Plasticity and Stemness
- (2020) Ralf Hass et al. Cancers
- Stem cell quiescence and its clinical relevance
- (2020) Meng Luo et al. World Journal of Stem Cells
- Cancer Stem Cells: The Architects of the Tumor Ecosystem
- (2019) Briana C. Prager et al. Cell Stem Cell
- Aldehyde Dehydrogenases: Not Just Markers, but Functional Regulators of Stem Cells
- (2019) Giuseppe Vassalli Stem Cells International
- The Genomic Health of Human Pluripotent Stem Cells: Genomic Instability and the Consequences on Nuclear Organization
- (2019) Marianne P. Henry et al. Frontiers in Genetics
- Glioblastoma Stem-Like Cells, Metabolic Strategy to Kill a Challenging Target
- (2019) Delphine Garnier et al. Frontiers in Oncology
- Role of Notch Signaling Pathway in Glioblastoma Multiforme Pathogenesis
- (2019) Riccardo Bazzoni et al. Cancers
- Evolution of Stress-Induced Mutagenesis in the Presence of Horizontal Gene Transfer
- (2019) Yoav Ram et al. AMERICAN NATURALIST
- Thrombospondin 1 and Its Diverse Roles as a Regulator of Extracellular Matrix in Fibrotic Disease
- (2019) Joanne E. Murphy-Ullrich JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Analysis of the high-dose-range radioresistance of prostate cancer cells, including cancer stem cells, based on a stochastic model
- (2019) Ryo Saga et al. JOURNAL OF RADIATION RESEARCH
- Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistance
- (2019) Micol Eleonora Fiori et al. Molecular Cancer
- Notch and breast cancer metastasis: Current knowledge, new sights and targeted therapy (Review)
- (2019) Yu Zhang et al. Oncology Letters
- Tumor Microenvironment and Cell Fusion
- (2019) Erhui Jiang et al. Biomed Research International
- Cancer Stem Cells and Radioresistance: DNA Repair and Beyond
- (2019) Alexander Schulz et al. Cancers
- Presence and role of stem cells in ovarian cancer
- (2019) Natasa Kenda Suster et al. World Journal of Stem Cells
- Cancer-Associated Fibroblasts Build and Secure the Tumor Microenvironment
- (2019) Tianyi Liu et al. Frontiers in Cell and Developmental Biology
- The cell cycle in stem cell proliferation, pluripotency and differentiation
- (2019) Lijun Liu et al. NATURE CELL BIOLOGY
- Cancer Cell Dormancy in Metastasis
- (2019) Matthew A. Summers et al. Cold Spring Harbor Perspectives in Medicine
- Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer
- (2019) Maria Pelullo et al. Frontiers in Genetics
- Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models
- (2019) Okada et al. Cells
- Current progress and future perspectives of polypharmacology : From the view of non-small cell lung cancer
- (2019) Ramanathan Karuppasamy et al. SEMINARS IN CANCER BIOLOGY
- Clonal pattern dynamics in tumor: the concept of cancer stem cells
- (2019) Fabrizio Olmeda et al. Scientific Reports
- Wnt Signaling in Ovarian Cancer Stemness, EMT, and Therapy Resistance
- (2019) Teeuwssen et al. Journal of Clinical Medicine
- Therapeutic Strategies Targeting Cancer Stem Cells and Their Microenvironment
- (2019) Hao-Ran Sun et al. Frontiers in Oncology
- Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches
- (2019) Karen G. de la Cruz-López et al. Frontiers in Oncology
- Correlating tumor-infiltrating lymphocytes and lung cancer stem cells: a cross-sectional study
- (2019) Valentina Masciale et al. Annals of Translational Medicine
- Cancer stem cells-driven tumor growth and immune escape: the Janus face of neurotrophins
- (2019) Viviana Triaca et al. Aging-US
- Mechanisms of Metastatic Tumor Dormancy and Implications for Cancer Therapy
- (2019) Christiana M. Neophytou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis
- (2019) Vu Hong Loan Nguyen et al. Journal of Ovarian Research
- WNT Signaling in Tumors: The Way to Evade Drugs and Immunity
- (2019) Elena Martin-Orozco et al. Frontiers in Immunology
- Isolation and Identification of Cancer Stem-Like Cells in Adenocarcinoma and Squamous Cell Carcinoma of the Lung: A Pilot Study
- (2019) Valentina Masciale et al. Frontiers in Oncology
- Contribution of Angiogenesis to Inflammation and Cancer
- (2019) Dolores Aguilar-Cazares et al. Frontiers in Oncology
- Cancer stem cells (CSCs): metabolic strategies for their identification and eradication
- (2018) Ernestina M. De Francesco et al. BIOCHEMICAL JOURNAL
- CD10 + GPR77 + Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
- (2018) Shicheng Su et al. CELL
- Emerging role of exosome signalling in maintaining cancer stem cell dynamic equilibrium
- (2018) Zhen Sun et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The viable circulating tumor cells with cancer stem cells feature, where is the way out?
- (2018) Y. T. Luo et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Emerging functional markers for cancer stem cell-based therapies: Understanding signaling networks for targeting metastasis
- (2018) Stephan Marquardt et al. SEMINARS IN CANCER BIOLOGY
- The Notch Pathway in Breast Cancer Progression
- (2018) Emmanuel N. Kontomanolis et al. TheScientificWorldJOURNAL
- Correlation of Cancer Stem-Cell Markers OCT4, SOX2, and NANOG with Clinicopathological Features and Prognosis in Operative Patients with Rectal Cancer
- (2018) Liuping You et al. YONSEI MEDICAL JOURNAL
- Metabolic Reprogramming of Cancer Associated Fibroblasts: The Slavery of Stromal Fibroblasts
- (2018) Angelica Avagliano et al. Biomed Research International
- The Notch Pathway in Breast Cancer Progression
- (2018) Emmanuel N. Kontomanolis et al. Scientific World Journal
- Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and Epigenetics
- (2018) Vittoria Poli et al. Stem Cells International
- Alteration of the Antitumor Immune Response by Cancer-Associated Fibroblasts
- (2018) Linda Ziani et al. Frontiers in Immunology
- Emerging mechanisms of asymmetric stem cell division
- (2018) Zsolt G. Venkei et al. JOURNAL OF CELL BIOLOGY
- Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin
- (2018) Hideaki Goto et al. ONCOGENE
- Expansion of cancer stem cell pool initiates lung cancer recurrence before angiogenesis
- (2018) Lei Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Can Stemness and Chemoresistance Be Therapeutically Targeted via Signaling Pathways in Ovarian Cancer?
- (2018) Lynn Roy et al. Cancers
- Roles of the immune system in cancer: from tumor initiation to metastatic progression
- (2018) Hugo Gonzalez et al. GENES & DEVELOPMENT
- Cancer stem cells (CSCs) in cancer progression and therapy
- (2018) Masoud Najafi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Evolution of Cancer Pharmacological Treatments at the Turn of the Third Millennium
- (2018) Luca Falzone et al. Frontiers in Pharmacology
- The Role of the Extracellular Matrix and Its Molecular and Cellular Regulators in Cancer Cell Plasticity
- (2018) Valentina Poltavets et al. Frontiers in Oncology
- Stem Cell Plasticity and Niche Dynamics in Cancer Progression
- (2017) Noemi Picco et al. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
- Drug Resistance Driven by Cancer Stem Cells and Their Niche
- (2017) Marta Prieto-Vila et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression
- (2017) Eunsun Kim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Catching moving targets: cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention
- (2017) Claudia Gasch et al. Molecular Cancer
- Cancer stem cell niche models and contribution by mesenchymal stroma/stem cells
- (2017) Catharina Melzer et al. Molecular Cancer
- Intra-tumor heterogeneity from a cancer stem cell perspective
- (2017) Pramudita R. Prasetyanti et al. Molecular Cancer
- Tumor cell dormancy
- (2017) Roger R. Gomis et al. Molecular Oncology
- A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
- (2017) Felipe de Sousa e Melo et al. NATURE
- Identification of essential genes for cancer immunotherapy
- (2017) Shashank J. Patel et al. NATURE
- EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
- (2017) Tsukasa Shibue et al. Nature Reviews Clinical Oncology
- Epigenetic plasticity and the hallmarks of cancer
- (2017) William A. Flavahan et al. SCIENCE
- Cancer stem cells: The root of tumor recurrence and metastases
- (2017) Claudia Peitzsch et al. SEMINARS IN CANCER BIOLOGY
- Overview of Cancer Stem Cells and Stemness for Community Oncologists
- (2017) Justin D. Lathia et al. Targeted Oncology
- Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer
- (2017) Woosung Chung et al. Nature Communications
- 3D modeling of cancer stem cell niche
- (2017) Jun He et al. Oncotarget
- MicroRNA-34a inhibits cells proliferation and invasion by downregulating Notch1 in endometrial cancer
- (2017) Zhen Wang et al. Oncotarget
- Progress in Exosome Isolation Techniques
- (2017) Pin Li et al. Theranostics
- Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment
- (2017) Pedro M. Aponte et al. Stem Cells International
- Cancer Stem Cells and Their Microenvironment: Biology and Therapeutic Implications
- (2017) Eunice Yuen-Ting Lau et al. Stem Cells International
- Exosome-Based Cancer Therapy: Implication for Targeting Cancer Stem Cells
- (2017) Jinheng Wang et al. Frontiers in Pharmacology
- In vitro models of cancer stem cells and clinical applications
- (2016) Sara S. Franco et al. BMC CANCER
- A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
- (2016) Christopher G. Hubert et al. CANCER RESEARCH
- Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT
- (2016) Srinivas Malladi et al. CELL
- Chemoradiotherapy of locally advanced nonsmall cell lung cancer
- (2016) Delphine Antoni et al. CURRENT OPINION IN ONCOLOGY
- Engineered Nanoparticles Against MDR in Cancer: The State of the Art and its Prospective
- (2016) Javed Ahmad et al. CURRENT PHARMACEUTICAL DESIGN
- Replicator dynamics of cancer stem cell: Selection in the presence of differentiation and plasticity
- (2016) Kamran Kaveh et al. MATHEMATICAL BIOSCIENCES
- Cancer stem cells
- (2016) Jeremy N. Rich et al. MEDICINE
- Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells
- (2016) Myung Soo Kim et al. Nanomedicine-Nanotechnology Biology and Medicine
- Precision medicine
- (2016) Richard Hodson NATURE
- Adult cell plasticity in vivo: de-differentiation and transdifferentiation are back in style
- (2016) Allyson J. Merrell et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cancer Stem Cell Hypothesis for Therapeutic Innovation in Clinical Oncology? Taking the Root Out, Not Chopping the Leaf
- (2016) Kevin Dzobo et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer
- (2016) A E Witt et al. ONCOGENE
- Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells
- (2016) Yang You et al. Oncotarget
- On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer
- (2016) Judith Penkert et al. Oncotarget
- Aldehyde dehydrogenase 1A1 in stem cells and cancer
- (2016) Hiroyuki Tomita et al. Oncotarget
- The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression
- (2016) Jiandong Chen Cold Spring Harbor Perspectives in Medicine
- Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy
- (2016) Wanyin Chen et al. Stem Cells International
- Drug Delivery Using Nanoparticles for Cancer Stem-Like Cell Targeting
- (2016) Bing Lu et al. Frontiers in Pharmacology
- Detection of circulating tumor cells in non-small cell lung cancer
- (2016) Gerhard Hamilton et al. Journal of Thoracic Disease
- Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment
- (2015) Xiao-xiao Sun et al. ACTA PHARMACOLOGICA SINICA
- Cell-of-Origin of Cancer versus Cancer Stem Cells: Assays and Interpretations
- (2015) K. Rycaj et al. CANCER RESEARCH
- Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
- (2015) Peter D. Adams et al. Cell Stem Cell
- The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?
- (2015) Vicki Plaks et al. Cell Stem Cell
- Fibronectin Mechanobiology Regulates Tumorigenesis
- (2015) Karin Wang et al. Cellular and Molecular Bioengineering
- Cancer stem cells: a potential target for cancer therapy
- (2015) Hong Qiu et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Molecular Pathways: Novel Approaches for Improved Therapeutic Targeting of Hedgehog Signaling in Cancer Stem Cells
- (2015) Verline Justilien et al. CLINICAL CANCER RESEARCH
- Cancer stem cells and the tumor microenvironment: interplay in tumor heterogeneity
- (2015) Adriana Albini et al. CONNECTIVE TISSUE RESEARCH
- Cancer stem cell: Fundamental experimental pathological concepts and updates
- (2015) Farhadul Islam et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Cancer stem cells in glioblastoma
- (2015) Justin D. Lathia et al. GENES & DEVELOPMENT
- Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
- (2015) Wenchao Zhou et al. NATURE CELL BIOLOGY
- Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update
- (2015) Naoko Takebe et al. Nature Reviews Clinical Oncology
- Targeting the WNT Signaling Pathway in Cancer Therapeutics
- (2015) D. Tai et al. ONCOLOGIST
- Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened
- (2015) Annelies Gonnissen et al. Oncotarget
- Signal Transduction in Cancer
- (2015) R. Sever et al. Cold Spring Harbor Perspectives in Medicine
- Hedgehog Signaling in the Maintenance of Cancer Stem Cells
- (2015) Catherine Cochrane et al. Cancers
- Increased Notch Signaling Enhances Radioresistance of Malignant Stromal Cells Induced by Glioma Stem/ Progenitor Cells
- (2015) Yuntian Shen et al. PLoS One
- The functional role of long non-coding RNAs and epigenetics
- (2014) Jinneng Cao BIOLOGICAL PROCEDURES ONLINE
- Cancer Cell Dormancy in Novel Mouse Models for Reversible Pancreatic Cancer: A Lingering Challenge in the Development of Targeted Therapies
- (2014) Wan-Chi Lin et al. CANCER RESEARCH
- Evolution of the Cancer Stem Cell Model
- (2014) Antonija Kreso et al. Cell Stem Cell
- Essential Role of Aldehyde Dehydrogenase 1A3 for the Maintenance of Non-Small Cell Lung Cancer Stem Cells Is Associated with the STAT3 Pathway
- (2014) C. Shao et al. CLINICAL CANCER RESEARCH
- Dedifferentiation and reprogramming: origins of cancer stem cells
- (2014) D. Friedmann-Morvinski et al. EMBO REPORTS
- Tumor heterogeneity and cancer stem cell paradigm: Updates in concept, controversies and clinical relevance
- (2014) Anup Kumar Singh et al. INTERNATIONAL JOURNAL OF CANCER
- Influence of the microenvironment on cell fate determination and migration
- (2014) Alexander B. Bloom et al. PHYSIOLOGICAL GENOMICS
- EMT and Acquisition of Stem Cell-Like Properties Are Involved in Spontaneous Formation of Tumorigenic Hybrids between Lung Cancer and Bone Marrow-Derived Mesenchymal Stem Cells
- (2014) Mei-Hua Xu et al. PLoS One
- Hypoxia Promotes Migration and Induces CXCR4 Expression via HIF-1α Activation in Human Osteosarcoma
- (2014) Mingjun Guo et al. PLoS One
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- Regulation of Wnt/β-catenin signaling by posttranslational modifications
- (2014) Chenxi Gao et al. Cell and Bioscience
- Cancer Stem Cell Immunology: Key to Understanding Tumorigenesis and Tumor Immune Escape?
- (2014) Valentin S. Bruttel et al. Frontiers in Immunology
- An emerging role for long non-coding RNAs in cancer metastasis
- (2014) Jason T. Serviss et al. Frontiers in Genetics
- Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells
- (2013) S Suman et al. BRITISH JOURNAL OF CANCER
- Tumor Cell Dissemination: Emerging Biological Insights from Animal Models and Cancer Patients
- (2013) Yibin Kang et al. CANCER CELL
- Asymmetric cell division of stem and progenitor cells during homeostasis and cancer
- (2013) Sandra Gómez-López et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance
- (2013) Florian A. Siebzehnrubl et al. EMBO Molecular Medicine
- Human NK Cells Selective Targeting of Colon Cancer-Initiating Cells: A Role for Natural Cytotoxicity Receptors and MHC Class I Molecules
- (2013) R. Tallerico et al. JOURNAL OF IMMUNOLOGY
- Starvation favors glioma stem cells
- (2013) Shirin Ilkhanizadeh et al. NATURE NEUROSCIENCE
- Molecular regulation of stem cell quiescence
- (2013) Tom H. Cheung et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers
- (2013) N. E. Buckley et al. NUCLEIC ACIDS RESEARCH
- Activation of the phosphorylation of ATM contributes to radioresistance of glioma stem cells
- (2013) WEI ZHOU et al. ONCOLOGY REPORTS
- Cancer stem cells and their role in metastasis
- (2013) Yusuke Shiozawa et al. PHARMACOLOGY & THERAPEUTICS
- Tumor and its microenvironment: A synergistic interplay
- (2013) Veronica Catalano et al. SEMINARS IN CANCER BIOLOGY
- Circulating tumor cells and DNA as liquid biopsies
- (2013) Ellen Heitzer et al. Genome Medicine
- Enhancing CHK1 inhibitor lethality in glioblastoma
- (2012) Yong Tang et al. CANCER BIOLOGY & THERAPY
- Cell Plasticity and Heterogeneity in Cancer
- (2012) N. D. Marjanovic et al. CLINICAL CHEMISTRY
- An Overview of Notch Signaling in Adult Tissue Renewal and Maintenance
- (2012) Chihiro Sato et al. Current Alzheimer Research
- Cancer stem cell hypothesis: a brief summary and two proposals
- (2012) Shuhua Zheng et al. CYTOTECHNOLOGY
- The retinoblastoma tumor suppressor and stem cell biology
- (2012) J. Sage GENES & DEVELOPMENT
- β1 Integrins restrict the growth of foci and spheroids
- (2012) Rajesh Kumar Gupta et al. HISTOCHEMISTRY AND CELL BIOLOGY
- The evolving concept of cancer and metastasis stem cells
- (2012) Irène Baccelli et al. JOURNAL OF CELL BIOLOGY
- The Cancer Stem-Cell Hypothesis: Its Emerging Role in Lung Cancer Biology and Its Relevance for Future Therapy
- (2012) John D. O’Flaherty et al. Journal of Thoracic Oncology
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Silencing Notch-1 induces apoptosis and increases the chemosensitivity of prostate cancer cells to docetaxel through Bcl-2 and Bax
- (2012) Le-Ye He Oncology Letters
- Stem Cell Quiescence
- (2011) L. Li et al. CLINICAL CANCER RESEARCH
- Targeting ALDHbright Human Carcinoma-Initiating Cells with ALDH1A1-Specific CD8+ T Cells
- (2011) C. Visus et al. CLINICAL CANCER RESEARCH
- Proteolytic Cleavage of Notch: “HIT and RUN”
- (2011) G. van Tetering et al. CURRENT MOLECULAR MEDICINE
- Extracellular matrix players in metastatic niches
- (2011) Thordur Oskarsson et al. EMBO JOURNAL
- Notch signaling and Notch signaling modifiers
- (2011) Michael M. Wang INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Breast cancer stem cells, cytokine networks, and the tumor microenvironment
- (2011) Hasan Korkaya et al. JOURNAL OF CLINICAL INVESTIGATION
- Head and Neck Cancer Stem Cells
- (2011) S. Krishnamurthy et al. JOURNAL OF DENTAL RESEARCH
- A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours
- (2011) Benjamin Beck et al. NATURE
- Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration
- (2011) Chris Jopling et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo
- (2011) A. B. Gaur et al. NEURO-ONCOLOGY
- Cancer Stem Cells Can Arise From Differentiated Neoplastic Cells
- (2011) Rahul Jandial et al. NEUROSURGERY
- Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
- (2011) D. Iliopoulos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting stroma to treat cancers
- (2011) Boris Engels et al. SEMINARS IN CANCER BIOLOGY
- Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling
- (2010) J. P. Sullivan et al. CANCER RESEARCH
- Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients
- (2010) T. Di Tomaso et al. CLINICAL CANCER RESEARCH
- Induced pluripotency: history, mechanisms, and applications
- (2010) M. Stadtfeld et al. GENES & DEVELOPMENT
- Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells
- (2010) Jörg Schrader et al. HEPATOLOGY
- Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
- (2010) Johanna Chiche et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The therapeutic promise of the cancer stem cell concept
- (2010) Natasha Y. Frank et al. JOURNAL OF CLINICAL INVESTIGATION
- Essential Roles of Notch Signaling in Maintenance of Neural Stem Cells in Developing and Adult Brains
- (2010) I. Imayoshi et al. JOURNAL OF NEUROSCIENCE
- Genetic variegation of clonal architecture and propagating cells in leukaemia
- (2010) Kristina Anderson et al. NATURE
- Review: Targeting the Hedgehog pathway in cancer
- (2010) Sachin Gupta et al. Therapeutic Advances in Medical Oncology
- Identification and targeting of cancer stem cells
- (2009) Tobias Schatton et al. BIOESSAYS
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Lessons from development: A role for asymmetric stem cell division in cancer
- (2009) Anne E. Powell et al. Stem Cell Research
- Notch Promotes Radioresistance of Glioma Stem Cells
- (2009) Jialiang Wang et al. STEM CELLS
- Notch Pathway Blockade Depletes CD133-Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts
- (2009) Xing Fan et al. STEM CELLS
- Tumor-induced upregulation of Twist, Snail, and Slug represses the activity of the human VE-cadherin promoter
- (2008) Dayami Lopez et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Repression of chondrogenesis through binding of notch signaling proteins HES-1 and HEY-1 to N-box domains in the COL2A1 enhancer site
- (2008) Shawn P. Grogan et al. ARTHRITIS AND RHEUMATISM
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation