The Role of Tumor-Stroma Interactions in Drug Resistance Within Tumor Microenvironment
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Title
The Role of Tumor-Stroma Interactions in Drug Resistance Within Tumor Microenvironment
Authors
Keywords
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Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-05-20
DOI
10.3389/fcell.2021.637675
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Note: Only part of the references are listed.- Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
- (2021) Helena Van Damme et al. Journal for ImmunoTherapy of Cancer
- Fc-optimized Anti-CCR8 Antibody Depletes Regulatory T Cells in Human Tumor Models
- (2021) Joseph R Campbell et al. CANCER RESEARCH
- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Adipocyte-induced FABP4 expression in ovarian cancer cells promotes metastasis and mediates carboplatin resistance
- (2020) Abir Mukherjee et al. CANCER RESEARCH
- Genetic and Epigenetic Modulation of Drug Resistance in Cancer: Challenges and Opportunities
- (2020) Kanisha Shah et al. CURRENT DRUG METABOLISM
- CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer
- (2020) Haiyang Zhang et al. Molecular Cancer
- Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1
- (2020) Caroline Imbert et al. Nature Communications
- Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas
- (2020) Katrin Aslan et al. Nature Communications
- Antiplatelet Drug Ticagrelor Enhances Chemotherapeutic Efficacy by Targeting the Novel P2Y12-AKT Pathway in Pancreatic Cancer Cells
- (2020) Omar Elaskalani et al. Cancers
- Activated HIF1α of tumor cells promotes chemoresistance development via recruiting GDF15-producing tumor-associated macrophages in gastric cancer
- (2020) Shan Yu et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
- (2020) Eslam Mohamed et al. IMMUNITY
- The immunological Warburg effect: Can a metabolic‐tumor‐stroma score (MeTS) guide cancer immunotherapy?
- (2020) Peter J. Siska et al. IMMUNOLOGICAL REVIEWS
- Tumor Endothelial Cell—A Biological Tool for Translational Cancer Research
- (2020) Dorcas Akuba-Muhyia Annan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p/AMPK/PGC1α/CEBPB axis to promote stemness and chemo-resistance of gastric cancer
- (2020) Honglei Wu et al. Cell Death & Disease
- The Role of Exosomal microRNA in Cancer Drug Resistance
- (2020) Qiao-ru Guo et al. Frontiers in Oncology
- Activation PDGFR-α/AKT Mediated Signaling Pathways in Oral Squamous Cell Carcinoma by Mesenchymal Stem/Stromal Cells Promotes Anti-apoptosis and Decreased Sensitivity to Cisplatin
- (2020) Jia Wang et al. Frontiers in Oncology
- Clinical development of therapies targeting TGFβ: current knowledge and future perspectives.
- (2020) D. Ciardiello et al. ANNALS OF ONCOLOGY
- Chemotherapy-induced IL-8 upregulates MDR1/ABCB1 in tumor blood vessels and results in unfavorable outcome
- (2020) Hiroshi Kikuchi et al. CANCER RESEARCH
- Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance
- (2020) Leila Akkari et al. Science Translational Medicine
- The CXCR4 Antagonist, AMD3100, Reverses Mesenchymal Stem Cell-Mediated Drug Resistance in Relapsed/Refractory Acute Lymphoblastic Leukemia
- (2020) Shan Wang et al. OncoTargets and Therapy
- Carcinoma-Associated Mesenchymal Stem Cells Promote Chemoresistance in Ovarian Cancer Stem Cells via PDGF Signaling
- (2020) Shreya Raghavan et al. Cancers
- A phase 2 study of ATRA, arsenic trioxide, and gemtuzumab ozogamicin in patients with high-risk APL (SWOG 0535)
- (2020) Jeffrey E. Lancet et al. Blood Advances
- CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of Receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 Ligands
- (2020) Jan Korbecki et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cancer immunotherapy via targeted TGF-β signalling blockade in TH cells
- (2020) Shun Li et al. NATURE
- A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components
- (2020) Monique B. Nilsson et al. Science Translational Medicine
- Tumor Endothelial Cells (TECs) as Potential Immune Directors of the Tumor Microenvironment – New Findings and Future Perspectives
- (2020) Laurenz Nagl et al. Frontiers in Cell and Developmental Biology
- Updated European Association of Urology Guidelines on Renal Cell Carcinoma: Nivolumab plus Cabozantinib Joins Immune Checkpoint Inhibition Combination Therapies for Treatment-naïve Metastatic Clear-Cell Renal Cell Carcinoma
- (2020) Jens Bedke et al. EUROPEAN UROLOGY
- CD40-mediated immune cell activation enhances response to anti-PD1 in murine intrahepatic cholangiocarcinoma
- (2020) Laurence P. Diggs et al. JOURNAL OF HEPATOLOGY
- Mesenchymal stem/stromal cells: Developmental origin, tumorigenesis and translational cancer therapeutics
- (2020) Chenghai Li et al. Translational Oncology
- Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma
- (2019) Eva A. Ebbing et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Secretome profiling of heterotypic spheroids suggests a role of fibroblasts in HIF-1 pathway modulation and colorectal cancer photodynamic resistance
- (2019) María Julia Lamberti et al. CELLULAR ONCOLOGY
- MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer
- (2019) Wanming He et al. ONCOGENE
- Exosomes in the tumor microenvironment as mediators of cancer therapy resistance
- (2019) Irene Li et al. Molecular Cancer
- Lenvatinib plus pembrolizumab in patients with advanced endometrial cancer: an interim analysis of a multicentre, open-label, single-arm, phase 2 trial
- (2019) Vicky Makker et al. LANCET ONCOLOGY
- Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype
- (2019) Xiaolan Zhu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Treatment of advanced gastrointestinal cancer with genetically modified autologous mesenchymal stem cells: Results from the phase 1/2 TREAT-ME-1 trial
- (2019) Jobst Christian von Einem et al. INTERNATIONAL JOURNAL OF CANCER
- Blocking TREM-1+ Tumor-associated macrophages induced by hypoxia reverses immunosuppression and anti-PD-L1 resistance in liver cancer
- (2019) Qinchuan Wu et al. HEPATOLOGY
- Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
- (2019) Christopher J. Halbrook et al. Cell Metabolism
- Cancer-associated fibroblasts contribute to cisplatin resistance via modulating ANXA3 in lung cancer cells
- (2019) Limin Wang et al. CANCER SCIENCE
- Tumor-educated platelets
- (2019) Sjors G.J.G. In 't Veld et al. BLOOD
- Noncanonical TGFβ Pathway Relieves the Blockade of IL1β/TGFβ-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer
- (2019) Natalia Guillén Díaz-Maroto et al. CLINICAL CANCER RESEARCH
- Cisplatin resistant lung cancer cells promoted M2 polarization of tumor-associated macrophages via the Src/CD155/MIF functional pathway
- (2019) Wen-Chien Huang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer
- (2019) J. L. Hu et al. Molecular Cancer
- Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistance
- (2019) Micol Eleonora Fiori et al. Molecular Cancer
- Snail1-dependent cancer-associated fibroblasts induce epithelial-mesenchymal transition in lung cancer cells via exosomes
- (2019) J You et al. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
- Metformin enhances gefitinib efficacy by interfering with interactions between tumor-associated macrophages and head and neck squamous cell carcinoma cells
- (2019) Xiteng Yin et al. CELLULAR ONCOLOGY
- Cancer-associated fibroblasts-derived IL-8 mediates resistance to cisplatin in human gastric cancer
- (2019) Jing Zhai et al. CANCER LETTERS
- Exosomal miRNA-106b from cancer-associated fibroblast promotes gemcitabine resistance in pancreatic cancer
- (2019) Yuan Fang et al. EXPERIMENTAL CELL RESEARCH
- Bone marrow-derived mesenchymal stromal cells promote resistance to tyrosine kinase inhibitors in chronic myeloid leukemia via the IL-7/JAK1/STAT5 pathway
- (2019) Xiaoyan Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Akt-activated endothelium promotes ovarian cancer proliferation through notch activation
- (2019) Jessica Hoarau-Véchot et al. Journal of Translational Medicine
- Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer‐associated fibroblasts with EGFR‐TKI resistance‐promoting phenotype—A study of 18 cases of cancer‐associated fibroblasts
- (2019) Erika Suzuki et al. PATHOLOGY INTERNATIONAL
- A Phase I Study of the Anti-CC Chemokine Receptor 4 Antibody, Mogamulizumab, in Combination with Nivolumab in Patients with Advanced or Metastatic Solid Tumors
- (2019) Toshihiko Doi et al. CLINICAL CANCER RESEARCH
- Long noncoding RNA CCAL transferred from fibroblasts by exosomes promotes chemoresistance of colorectal cancer cells
- (2019) Xuan Deng et al. INTERNATIONAL JOURNAL OF CANCER
- Colorectal cancer cell-derived CCL20 recruits regulatory T cells to promote chemoresistance via FOXO1/CEBPB/NF-κB signaling
- (2019) Dan Wang et al. Journal for ImmunoTherapy of Cancer
- MDSC targeting with Gemtuzumab ozogamicin restores T cell immunity and immunotherapy against cancers
- (2019) Livingstone Fultang et al. EBioMedicine
- CSF1R‐ and SHP2‐Inhibitor‐Loaded Nanoparticles Enhance Cytotoxic Activity and Phagocytosis in Tumor‐Associated Macrophages
- (2019) Anujan Ramesh et al. ADVANCED MATERIALS
- Dysregulation of glutamate transport enhances Treg function that promotes VEGF blockade resistance in glioblastoma
- (2019) Yu Long et al. CANCER RESEARCH
- Tumor-infiltrating platelets predict postoperative recurrence and survival in resectable pancreatic neuroendocrine tumor
- (2019) Shuai-Shuai Xu et al. WORLD JOURNAL OF GASTROENTEROLOGY
- CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
- (2019) Claire Vennin et al. Nature Communications
- Adipocytes promote ovarian cancer chemoresistance
- (2019) Jiang Yang et al. Scientific Reports
- Aspirin suppresses chemoresistance and enhances antitumor activity of 5-Fu in 5-Fu-resistant colorectal cancer by abolishing 5-Fu-induced NF-κB activation
- (2019) Jinbo Fu et al. Scientific Reports
- Tumor Endothelial Heterogeneity in Cancer Progression
- (2019) Nako Maishi et al. Cancers
- Gemtuzumab Ozogamicin in NPM1-Mutated Acute Myeloid Leukemia: Early Results From the Prospective Randomized AMLSG 09-09 Phase III Study
- (2019) Richard F. Schlenk et al. JOURNAL OF CLINICAL ONCOLOGY
- Harnessing tumor-associated macrophages as aids for cancer immunotherapy
- (2019) Xiaolei Li et al. Molecular Cancer
- Cancer-associated fibroblasts promote epithelial-mesenchymal transition and EGFR-TKI resistance of non-small cell lung cancers via HGF/IGF-1/ANXA2 signaling
- (2018) Yanmei Yi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Simultaneous inhibition of hedgehog signaling and tumor proliferation remodels stroma and enhances pancreatic cancer therapy
- (2018) Jun Zhao et al. BIOMATERIALS
- Animal models for studying tumor microenvironment (TME) and resistance to lymphocytic infiltration
- (2018) Ryuji Yamaguchi et al. CANCER BIOLOGY & THERAPY
- HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance
- (2018) Shou Liu et al. CANCER RESEARCH
- Autocrine Adenosine regulates tumor polyfunctional CD73+CD4+ effector T cells devoid of immune checkpoints
- (2018) Nicolas Gourdin et al. CANCER RESEARCH
- Reverse of non-small cell lung cancer drug resistance induced by cancer-associated fibroblasts via a paracrine pathway
- (2018) Quanhui Zhang et al. CANCER SCIENCE
- Reciprocal Network between Cancer Stem-Like Cells and Macrophages Facilitates the Progression and Androgen Deprivation Therapy Resistance of Prostate Cancer
- (2018) Hai Huang et al. CLINICAL CANCER RESEARCH
- PMN-MDSC and arginase are increased in myeloma and may contribute to resistance to therapy
- (2018) Alessandra Romano et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Microenvironment‑driven resistance to B‑Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts
- (2018) Ondřej Kodet et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Contribution of Tumor Endothelial Cells in Cancer Progression
- (2018) Kyoko Hida et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells
- (2018) Jiancheng Wang et al. Journal of Hematology & Oncology
- Phenotype molding of stromal cells in the lung tumor microenvironment
- (2018) Diether Lambrechts et al. NATURE MEDICINE
- Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis
- (2018) Andras Ladanyi et al. ONCOGENE
- Micro-RNA-21 Regulates Cancer-Associated Fibroblast-Mediated Drug Resistance in Pancreatic Cancer
- (2018) Lulin Zhang et al. ONCOLOGY RESEARCH
- Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer
- (2018) Yen-An Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adipocyte biology in breast cancer: From silent bystander to active facilitator
- (2018) Junjeong Choi et al. PROGRESS IN LIPID RESEARCH
- Cisplatin-activated PAI-1 secretion in the cancer-associated fibroblasts with paracrine effects promoting esophageal squamous cell carcinoma progression and causing chemoresistance
- (2018) Yun Che et al. Cell Death & Disease
- Defining the role of the tumor vasculature in antitumor immunity and immunotherapy
- (2018) Marco B. Schaaf et al. Cell Death & Disease
- Tumor‑derived mesenchymal‑stem‑cell‑secreted IL‑6 enhances resistance to cisplatin via the STAT3 pathway in breast cancer
- (2018) Huitao Xu et al. Oncology Letters
- Prognostic role of multidrug resistance‑associated protein 1 expression and platelet count in operable non‑small cell lung cancer
- (2018) Linming Fang et al. Oncology Letters
- Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
- (2018) Aurélie S. Cazet et al. Nature Communications
- Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins
- (2018) Maomao Zhang et al. Cancer Discovery
- Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19
- (2018) Jing Ren et al. Theranostics
- Cancer-Associated-Fibroblasts Promote the Chemo-Resistance in Gastric Cancer through Secreting IL-11 targeting JAK/STAT3/Bcl2 Pathway
- (2018) Jun Ma et al. Cancer Research and Treatment
- Participation of CCL1 in Snail-Positive Fibroblasts in Colorectal Cancer Contribute to 5-Fluorouracil/Paclitaxel Chemoresistance
- (2018) Ziqian Li et al. Cancer Research and Treatment
- Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition
- (2018) Cristiana Perrotta et al. Frontiers in Immunology
- Transfer of miRNA in Macrophage-Derived Exosomes Induces Drug Resistance in Pancreatic Adenocarcinoma
- (2018) Yoav Binenbaum et al. CANCER RESEARCH
- Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
- (2018) Maria Apicella et al. Cell Metabolism
- High Platelet Levels Attenuate the Efficacy of Platinum-Based Treatment in Non-Small Cell Lung Cancer
- (2018) Zhangfei Wang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming
- (2018) Rajeev Mishra et al. JOURNAL OF CLINICAL INVESTIGATION
- IL-6-mediated cross-talk between human preadipocytes and ductal carcinoma in situ in breast cancer progression
- (2018) Hoe Suk Kim et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- IL-23 secreted by myeloid cells drives castration-resistant prostate cancer
- (2018) Arianna Calcinotto et al. NATURE
- PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma
- (2018) Tianrun Liu et al. Nature Communications
- Role of mesenchymal stromal cell-derived extracellular vesicles in tumour microenvironment
- (2018) A. Adamo et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Tumor microenvironment: Interactions and therapy
- (2018) Masoud Najafi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The epithelial-to-mesenchymal transition induced by tumor-associated macrophages confers chemoresistance in peritoneally disseminated pancreatic cancer
- (2018) Kazuya Kuwada et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Multipotent mesenchymal stromal cells play critical roles in hepatocellular carcinoma initiation, progression and therapy
- (2018) Zeli Yin et al. Molecular Cancer
- Platelet-to-lymphocyte ratio as a predictive factor of complete pathologic response to neoadjuvant chemotherapy in breast cancer
- (2018) Javier Cuello-López et al. PLoS One
- Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer
- (2018) Lusheng Wei et al. Cell Death & Disease
- M2 macrophage-derived IL6 mediates resistance of breast cancer cells to hedgehog inhibition
- (2018) Xiaojun Xu et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway
- (2018) Kim De Veirman et al. CANCER LETTERS
- Interactions between interleukin-6 and myeloid-derived suppressor cells drive the chemoresistant phenotype of hepatocellular cancer
- (2017) Min Xu et al. EXPERIMENTAL CELL RESEARCH
- Targeting both tumour-associated CXCR2+neutrophils and CCR2+macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma
- (2017) Timothy M Nywening et al. GUT
- The Role of Tumor Microenvironment in Chemoresistance: To Survive, Keep Your Enemies Closer
- (2017) Dimakatso Alice Senthebane et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance
- (2017) Cecilia S. Leung et al. JOURNAL OF CLINICAL INVESTIGATION
- After neoadjuvant chemotherapy platelet/lymphocyte ratios negatively correlate with prognosis in gastric cancer patients
- (2017) Weipeng Gong et al. JOURNAL OF CLINICAL LABORATORY ANALYSIS
- Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells
- (2017) Peiming Zheng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin
- (2017) Xia Sheng et al. MOLECULAR CANCER RESEARCH
- JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non–Small Cell Lung Cancer
- (2017) Kazuhiko Shien et al. MOLECULAR CANCER THERAPEUTICS
- EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
- (2017) Tsukasa Shibue et al. Nature Reviews Clinical Oncology
- DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells
- (2017) C Pistore et al. ONCOGENE
- IL6 derived from cancer-associated fibroblasts promotes chemoresistance via CXCR7 in esophageal squamous cell carcinoma
- (2017) Y Qiao et al. ONCOGENE
- Fibroblast Activation Protein-α-Positive Fibroblasts Promote Gastric Cancer Progression and Resistance to Immune Checkpoint Blockade
- (2017) Xuyang Wen et al. ONCOLOGY RESEARCH
- Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer
- (2017) Pasquale Sansone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The fat and the bad: Mature adipocytes, key actors in tumor progression and resistance
- (2017) Minh Ngoc Duong et al. Oncotarget
- Mesenchymal Stem Cell-Derived Extracellular Vesicles: Roles in Tumor Growth, Progression, and Drug Resistance
- (2017) Xiaoyan Zhang et al. Stem Cells International
- Myeloid-Derived Suppressor Cells
- (2017) Dmitry I. Gabrilovich Cancer Immunology Research
- DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment
- (2017) P Mathot et al. Oncogenesis
- Midkine derived from cancer-associated fibroblasts promotes cisplatin-resistance via up-regulation of the expression of lncRNA ANRIL in tumour cells
- (2017) Dongya Zhang et al. Scientific Reports
- Heterogeneity of tumor endothelial cells and drug delivery
- (2016) Kyoko Hida et al. ADVANCED DRUG DELIVERY REVIEWS
- Cancer-associated fibroblasts attenuate Cisplatin-induced apoptosis in ovarian cancer cells by promoting STAT3 signaling
- (2016) Huan Yan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy
- (2016) Anna Rita Cantelmo et al. CANCER CELL
- Macrophages induce resistance to 5-fluorouracil chemotherapy in colorectal cancer through the release of putrescine
- (2016) Xuan Zhang et al. CANCER LETTERS
- Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow
- (2016) Sarah A. Bliss et al. CANCER RESEARCH
- Chemotherapy-Induced IL34 Enhances Immunosuppression by Tumor-Associated Macrophages and Mediates Survival of Chemoresistant Lung Cancer Cells
- (2016) M. Baghdadi et al. CANCER RESEARCH
- Endothelial Side Population Cells Contribute to Tumor Angiogenesis and Antiangiogenic Drug Resistance
- (2016) H. Naito et al. CANCER RESEARCH
- Tumor-Derived CCL2 Mediates Resistance to Radiotherapy in Pancreatic Ductal Adenocarcinoma
- (2016) Anusha Kalbasi et al. CLINICAL CANCER RESEARCH
- Tumor-Associated Neutrophils Recruit Macrophages and T-Regulatory Cells to Promote Progression of Hepatocellular Carcinoma and Resistance to Sorafenib
- (2016) Shao-Lai Zhou et al. GASTROENTEROLOGY
- A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses
- (2016) Eric H. Bent et al. GENES & DEVELOPMENT
- Cisplatin-induced CCL5 secretion from CAFs promotes cisplatin-resistance in ovarian cancer via regulation of the STAT3 and PI3K/Akt signaling pathways
- (2016) BO ZHOU et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- The emerging roles of exosomes in tumor–stroma interaction
- (2016) Hailong Fu et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis
- (2016) Fei Teng et al. Journal of Hematology & Oncology
- Understanding the epigenetic regulation of tumours and their microenvironments: opportunities and problems for epigenetic therapy
- (2016) Man Liu et al. JOURNAL OF PATHOLOGY
- Cancer-associated fibroblasts mediated chemoresistance by a FOXO1/TGFβ1 signaling loop in esophageal squamous cell carcinoma
- (2016) Hongfang Zhang et al. MOLECULAR CARCINOGENESIS
- Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells
- (2016) Olivier De Henau et al. NATURE
- Targeting metastasis-initiating cells through the fatty acid receptor CD36
- (2016) Gloria Pascual et al. NATURE
- Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets
- (2016) Yufang Shi et al. NATURE REVIEWS DRUG DISCOVERY
- Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells
- (2016) K E Richards et al. ONCOGENE
- mir-1-mediated paracrine effect of cancer-associated fibroblasts on lung cancer cell proliferation and chemoresistance
- (2016) JIANMIN LI et al. ONCOLOGY REPORTS
- Involvement of platelets in tumor cell metastasis
- (2016) Belay Tesfamariam PHARMACOLOGY & THERAPEUTICS
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- (2016) Clara Di Vito et al. PLATELETS
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- (2016) Chi Lam Au Yeung et al. Nature Communications
- Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy
- (2016) J. Incio et al. Cancer Discovery
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- (2016) Valentina Folgiero et al. Oncotarget
- Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3
- (2016) Bing Tu et al. Oncotarget
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- (2016) Wen Yu et al. Oncotarget
- The role of p53 in cancer drug resistance and targeted chemotherapy
- (2016) Karin Hientz et al. Oncotarget
- Cancer-associated fibroblasts treated with cisplatin facilitates chemoresistance of lung adenocarcinoma through IL-11/IL-11R/STAT3 signaling pathway
- (2016) Leilei Tao et al. Scientific Reports
- Doxorubicin resistant cancer cells activate myeloid-derived suppressor cells by releasing PGE2
- (2016) Yuan Rong et al. Scientific Reports
- Resistance to Antiangiogenic Therapies by Metabolic Symbiosis in Renal Cell Carcinoma PDX Models and Patients
- (2016) Gabriela Jiménez-Valerio et al. Cell Reports
- Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling
- (2016) Elizabeth Allen et al. Cell Reports
- Wharton’s Jelly-Derived Mesenchymal Stromal Cells and Fibroblast-Derived Extracellular Matrix Synergistically Activate Apoptosis in a p21-Dependent Mechanism in WHCO1 and MDA MB 231 Cancer CellsIn Vitro
- (2016) Kevin Dzobo et al. Stem Cells International
- The Essential Role of Type I Interferons in Differentiation and Activation of Tumor-Associated Neutrophils
- (2016) Ekaterina Pylaeva et al. Frontiers in Immunology
- Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressing tumors
- (2016) Rikke B. Holmgaard et al. EBioMedicine
- Inhibition of Multidrug Transporter in Tumor Endothelial Cells Enhances Antiangiogenic Effects of Low-Dose Metronomic Paclitaxel
- (2015) Kosuke Akiyama et al. AMERICAN JOURNAL OF PATHOLOGY
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2015) Berna C. Özdemir et al. CANCER CELL
- Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling
- (2015) Eishu Hirata et al. CANCER CELL
- Tumor microenvironment: Sanctuary of the devil
- (2015) Lanlan Hui et al. CANCER LETTERS
- miR-27 is associated with chemoresistance in esophageal cancer through transformation of normal fibroblasts to cancer-associated fibroblasts
- (2015) Koji Tanaka et al. CARCINOGENESIS
- Exosomes derived from human mesenchymal stem cells confer drug resistance in gastric cancer
- (2015) Runbi Ji et al. CELL CYCLE
- Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients
- (2015) K. Kurose et al. CLINICAL CANCER RESEARCH
- Modulation of sensitivity and resistance to multikinase inhibitors by microenvironmental platelet factors in HCC
- (2015) Rosalba D’Alessandro et al. EXPERT OPINION ON PHARMACOTHERAPY
- Metabolic reprogramming: the emerging concept and associated therapeutic strategies
- (2015) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- High infiltration of tumor-associated macrophages is associated with a poor response to chemotherapy and poor prognosis of patients undergoing neoadjuvant chemotherapy for esophageal cancer
- (2015) Keijiro Sugimura et al. JOURNAL OF SURGICAL ONCOLOGY
- Increased drug resistance in breast cancer by tumor-associated macrophages through IL-10/STAT3/bcl-2 signaling pathway
- (2015) Cuixia Yang et al. MEDICAL ONCOLOGY
- Cancer-associated fibroblasts induce trastuzumab resistance in HER2 positive breast cancer cells
- (2015) Yan Mao et al. Molecular BioSystems
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma
- (2015) Fabienne Guillaumond et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stem Cell-Based Cell Carrier for Targeted Oncolytic Virotherapy: Translational Opportunity and Open Questions
- (2015) Janice Kim et al. Viruses-Basel
- Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation
- (2015) Zhiqiang Liu et al. Oncotarget
- The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer
- (2015) Mahiru Kawano et al. Scientific Reports
- Resistance to Antiangiogenic Therapy Is Associated with an Immunosuppressive Tumor Microenvironment in Metastatic Renal Cell Carcinoma
- (2015) X.-D. Liu et al. Cancer Immunology Research
- Bone marrow stromal cell-derived exosomes as communicators in drug resistance in multiple myeloma cells
- (2014) J. Wang et al. BLOOD
- A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer
- (2014) Nelma Pértega-Gomes et al. BMC CANCER
- Angiocrine Factors Deployed by Tumor Vascular Niche Induce B Cell Lymphoma Invasiveness and Chemoresistance
- (2014) Zhongwei Cao et al. CANCER CELL
- The origin and function of tumor-associated macrophages
- (2014) Yang Liu et al. Cellular & Molecular Immunology
- Differential Platelet Levels Affect Response to Taxane-Based Therapy in Ovarian Cancer
- (2014) Justin Bottsford-Miller et al. CLINICAL CANCER RESEARCH
- Adipocytes Contribute to Resistance of Human Melanoma Cells to Chemotherapy and Targeted Therapy
- (2014) M. Chi et al. CURRENT MEDICINAL CHEMISTRY
- TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells
- (2014) Horacio Cardenas et al. Epigenetics
- Angiogenesis revisited – role and therapeutic potential of targeting endothelial metabolism
- (2014) Peter Stapor et al. JOURNAL OF CELL SCIENCE
- Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice
- (2014) J.-I. Youn et al. JOURNAL OF IMMUNOLOGY
- Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy
- (2014) Bernardo Tavora et al. NATURE
- Tocilizumab, a Proposed Therapy for the Cachexia of Interleukin6-Expressing Lung Cancer
- (2014) Katsutoshi Ando et al. PLoS One
- Mesenchymal stem cells contribute to the chemoresistance of hepatocellular carcinoma cells in inflammatory environment by inducing autophagy
- (2014) Zhipeng Han et al. Cell and Bioscience
- Tumour-surrounding adipocytes are active players in breast cancer progression
- (2013) Catherine Muller ANNALES D ENDOCRINOLOGIE
- Adipose tissue and adipocytes support tumorigenesis and metastasis
- (2013) Kristin M. Nieman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt- -catenin signaling
- (2013) B. Zhang et al. BLOOD
- Adipocytes Cause Leukemia Cell Resistance to L-Asparaginase via Release of Glutamine
- (2013) E. A. Ehsanipour et al. CANCER RESEARCH
- Adipocyte-Derived Fibroblasts Promote Tumor Progression and Contribute to the Desmoplastic Reaction in Breast Cancer
- (2013) L. Bochet et al. CANCER RESEARCH
- Direct TGF-β1 signaling between activated platelets and pancreatic cancer cells primes cisplatin insensitivity
- (2013) Hongxu Chen et al. CELL BIOLOGY INTERNATIONAL
- Effects of Adjuvant Chemoradiotherapy on the Frequency and Function of Regulatory T Cells in Patients with Head and Neck Cancer
- (2013) P. J. Schuler et al. CLINICAL CANCER RESEARCH
- Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours
- (2013) Jiyoung Park et al. EMBO Molecular Medicine
- Hepatic stellate cells in liver development, regeneration, and cancer
- (2013) Chunyue Yin et al. JOURNAL OF CLINICAL INVESTIGATION
- Induction of acquired drug resistance in endothelial cells and its involvement in anticancer therapy
- (2013) Limin Huang et al. Journal of Hematology & Oncology
- Adipose tissue attracts and protects acute lymphoblastic leukemia cells from chemotherapy
- (2013) Rocky Pramanik et al. LEUKEMIA RESEARCH
- p53 regulates mesenchymal stem cell-mediated tumor suppression in a tumor microenvironment through immune modulation
- (2013) Y Huang et al. ONCOGENE
- Infiltrating bone marrow mesenchymal stem cells increase prostate cancer stem cell population and metastatic ability via secreting cytokines to suppress androgen receptor signaling
- (2013) J Luo et al. ONCOGENE
- Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase
- (2013) N Weizman et al. ONCOGENE
- Tumor Endothelial Cells Acquire Drug Resistance by MDR1 Up-Regulation via VEGF Signaling in Tumor Microenvironment
- (2012) Kosuke Akiyama et al. AMERICAN JOURNAL OF PATHOLOGY
- Platelets increase survival of adenocarcinoma cells challenged with anticancer drugs: mechanisms and implications for chemoresistance
- (2012) A Radziwon-Balicka et al. BRITISH JOURNAL OF PHARMACOLOGY
- Effective Combination Therapy for Malignant Glioma with TRAIL-Secreting Mesenchymal Stem Cells and Lipoxygenase Inhibitor MK886
- (2012) S. M. Kim et al. CANCER RESEARCH
- A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis
- (2012) Swarnali Acharyya et al. CELL
- Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
- (2012) Michael A Jacobetz et al. GUT
- Cancer-Associated Fibroblasts Induce Matrix Metalloproteinase-Mediated Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cells
- (2012) A.-C. Johansson et al. MOLECULAR CANCER RESEARCH
- Foxp3 overexpression decreases sensitivity to chemotherapy in mouse Lewis lung cancer cells
- (2012) CHUN LI et al. Molecular Medicine Reports
- BMSC enhance the survival of paclitaxel treated squamous cell carcinoma cells in vitro
- (2011) Agmal Scherzed et al. CANCER BIOLOGY & THERAPY
- Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis
- (2011) Myriam Labelle et al. CANCER CELL
- Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids
- (2011) Jeanine M.L. Roodhart et al. CANCER CELL
- Targeted Methylation of Two Tumor Suppressor Genes Is Sufficient to Transform Mesenchymal Stem Cells into Cancer Stem/Initiating Cells
- (2011) I.-W. Teng et al. CANCER RESEARCH
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
- (2011) B. Dirat et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer
- (2011) T. Shree et al. GENES & DEVELOPMENT
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells
- (2011) M. Jinushi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transdifferentiation of glioblastoma cells into vascular endothelial cells
- (2011) Y. Soda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Concise Review: Mesenchymal Stem Cell Tumor-Homing: Detection Methods in Disease Model Systems
- (2011) Michaela R. Reagan et al. STEM CELLS
- Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: Evidence for stromal-epithelial metabolic coupling
- (2010) Gemma Migneco et al. CELL CYCLE
- Impact of Serum Hepatocyte Growth Factor on Treatment Response to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients with Non-Small Cell Lung Adenocarcinoma
- (2010) K. Kasahara et al. CLINICAL CANCER RESEARCH
- Mesenchymal stromal cells alone or expressing interferon-β suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment
- (2010) Shannon Kidd et al. CYTOTHERAPY
- Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells
- (2010) Monica Bartucci et al. ENDOCRINE-RELATED CANCER
- Bone marrow mesenchymal stromal cells non-selectively protect chronic myeloid leukemia cells from imatinib-induced apoptosis via the CXCR4/CXCL12 axis
- (2010) F. Vianello et al. HAEMATOLOGICA
- Tumor associated mesenchymal stem cells protects ovarian cancer cells from hyperthermia through CXCL12
- (2010) Raphael Lis et al. INTERNATIONAL JOURNAL OF CANCER
- Tumour-associated fibroblasts and mesenchymal stem cells: more similarities than differences
- (2010) Virgil Paunescu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Effect of Obesity on Prognosis After Early-Stage Breast Cancer
- (2010) Marianne Ewertz et al. JOURNAL OF CLINICAL ONCOLOGY
- Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture
- (2010) P. M. Gilbert et al. SCIENCE
- Cytogenetic Abnormalities of Tumor-Associated Endothelial Cells in Human Malignant Tumors
- (2009) Tomoshige Akino et al. AMERICAN JOURNAL OF PATHOLOGY
- Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN
- (2009) Zvi G. Fridlender et al. CANCER CELL
- Human Hepatocellular Carcinoma Tumor-derived Endothelial Cells Manifest Increased Angiogenesis Capability and Drug Resistance Compared with Normal Endothelial Cells
- (2009) Y.-Q. Xiong et al. CLINICAL CANCER RESEARCH
- Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes
- (2009) Fátima Pérez de Heredia et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells
- (2008) P. J. Mishra et al. CANCER RESEARCH
- Hematopoietic stem cell differentiation affects expression and function of MRP4 (ABCC4), a transport protein for signaling molecules and drugs
- (2008) Lena Oevermann et al. INTERNATIONAL JOURNAL OF CANCER
- Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2
- (2008) Eliane Angst et al. SURGERY
- Correlation of NK T-like CD3+CD56+ cells and CD4+CD25+(hi) regulatory T cells with VEGF and TNFα in ascites from advanced ovarian cancer: Association with platinum resistance and prognosis in patients receiving first-line, platinum-based chemotherapy
- (2007) Aristotelis Bamias et al. GYNECOLOGIC ONCOLOGY
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