BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers

Notch3 Functions as a Tumor Suppressor by Controlling Cellular Senescence

(2013) H. Cui et al.   CANCER RESEARCH

BRCA1 – Conductor of the Breast Stem Cell Orchestra: The Role of BRCA1 in Mammary Gland Development and Identification of Cell of Origin of BRCA1 Mutant Breast Cancer

(2012) Niamh E. Buckley et al.   Stem Cell Reviews and Reports

Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations

(2012) Nelson K. Y. Wong et al.   Cancer Medicine

The  Np63 Proteins Are Key Allies of BRCA1 in the Prevention of Basal-Like Breast Cancer

(2011) N. E. Buckley et al.   CANCER RESEARCH

Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate

(2011) Theresa A. Proia et al.   Cell Stem Cell

Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch

(2011) J. M. Haughian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Lethality through Combined Notch-Epidermal Growth Factor Receptor Pathway Inhibition in Basal-Like Breast Cancer

(2010) Y. Dong et al.   CANCER RESEARCH

Regulation of Breast Cancer Stem Cell Activity by Signaling through the Notch4 Receptor

(2010) H. Harrison et al.   CANCER RESEARCH

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

(2010) Ö Yalcin-Ozuysal et al.   CELL DEATH AND DIFFERENTIATION

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

(2010) Gemma Molyneux et al.   Cell Stem Cell

BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer

(2009) Julia J. Gorski et al.   BREAST CANCER RESEARCH AND TREATMENT

Molecular Distinctions between Stasis and Telomere Attrition Senescence Barriers Shown by Long-term Culture of Normal Human Mammary Epithelial Cells

(2009) J. C. Garbe et al.   CANCER RESEARCH

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors

(2008) Anita L. Bane et al.   BREAST CANCER RESEARCH AND TREATMENT

Molecular Dependence of Estrogen Receptor-Negative Breast Cancer on a Notch-Survivin Signaling Axis

(2008) C. W. Lee et al.   CANCER RESEARCH

Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

(2008) P. Rizzo et al.   CANCER RESEARCH

Transcriptome Analysis of the Normal Human Mammary Cell Commitment and Differentiation Process

(2008) Afshin Raouf et al.   Cell Stem Cell

Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment

(2008) Toula Bouras et al.   Cell Stem Cell

BRCA1 regulates human mammary stem/progenitor cell fate

(2008) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA