Pharmacological Targeting of Microglial Activation: New Therapeutic Approach
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmacological Targeting of Microglial Activation: New Therapeutic Approach
Authors
Keywords
-
Journal
Frontiers in Cellular Neuroscience
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-11-19
DOI
10.3389/fncel.2019.00514
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and Pathology
- (2019) Francesca Longhena et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Microglia as modulators of exosomal alpha-synuclein transmission
- (2019) Yun Xia et al. Cell Death & Disease
- A modular analysis of microglia gene expression, insights into the aged phenotype
- (2019) Christine E. Cho et al. BMC GENOMICS
- Temporal evolution of microglia and α-synuclein accumulation following foetal grafting in Parkinson’s disease
- (2019) C Warren Olanow et al. BRAIN
- Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease
- (2019) Runxiao Lv et al. LIFE SCIENCES
- CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
- (2019) John V. Pluvinage et al. NATURE
- Effects of Curcumin on Microglial Cells
- (2019) Faezeh Ghasemi et al. NEUROTOXICITY RESEARCH
- Toll-like receptors and their therapeutic potential in Parkinson’s disease and α-synucleinopathies
- (2019) Antonina Kouli et al. BRAIN BEHAVIOR AND IMMUNITY
- Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates
- (2019) Acuña et al. Cells
- Physical Exercise Inhibits Inflammation and Microglial Activation
- (2019) Mee-inta et al. Cells
- The multiple roles of exosomes in Parkinson's disease: an overview
- (2019) Chiara Porro et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson’s disease
- (2019) Sonia George et al. Molecular Neurodegeneration
- TREM2 modulates microglia phenotypes in the neuroinflammation of Parkinson's disease
- (2018) Youwen Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Astroglial and microglial contributions to iron metabolism disturbance in Parkinson's disease
- (2018) Ning Song et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Alpha-synuclein oligomers impair memory through glial cell activation and via Toll-like receptor 2
- (2018) Pietro La Vitola et al. BRAIN BEHAVIOR AND IMMUNITY
- Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB 1 and CB 2 receptors and relevance for Alzheimer’s disease and levodopa-induced dyskinesia
- (2018) Gemma Navarro et al. BRAIN BEHAVIOR AND IMMUNITY
- Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease
- (2018) Obdulia Rabal et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Aging modulates microglia phenotypes in neuroinflammation of MPTP-PD mice
- (2018) Kai Yao et al. EXPERIMENTAL GERONTOLOGY
- The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Na v 1.6
- (2018) Muhammad M. Hossain et al. EXPERIMENTAL NEUROLOGY
- TREM2 overexpression attenuates neuroinflammation and protects dopaminergic neurons in experimental models of Parkinson's disease
- (2018) Manru Ren et al. EXPERIMENTAL NEUROLOGY
- Microglia and Aging: The Role of the TREM2–DAP12 and CX3CL1-CX3CR1 Axes
- (2018) Carmen Mecca et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson’s Disease
- (2018) Valentina Caputi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Indomethacin promotes survival of new neurons in the adult murine hippocampus accompanied by anti-inflammatory effects following MPTP-induced dopamine depletion
- (2018) Elisabeth G. Hain et al. Journal of Neuroinflammation
- Microglial control of astrocytes in response to microbial metabolites
- (2018) Veit Rothhammer et al. NATURE
- Cannabinoid CB1 and CB2 Receptors, and Monoacylglycerol Lipase Gene Expression Alterations in the Basal Ganglia of Patients with Parkinson’s Disease
- (2018) Francisco Navarrete et al. Neurotherapeutics
- α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies
- (2018) Iryna Prots et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Inflammation-Centric View of Neurological Disease: Beyond the Neuron
- (2018) Stephen D. Skaper et al. Frontiers in Cellular Neuroscience
- Microglia Polarization, Gene-Environment Interactions and Wnt/β-Catenin Signaling: Emerging Roles of Glia-Neuron and Glia-Stem/Neuroprogenitor Crosstalk for Dopaminergic Neurorestoration in Aged Parkinsonian Brain
- (2018) Francesca L'Episcopo et al. Frontiers in Aging Neuroscience
- Microglial Phagocytosis and Its Regulation: A Therapeutic Target in Parkinson’s Disease?
- (2018) Elzbieta Janda et al. Frontiers in Molecular Neuroscience
- Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease
- (2018) Jessika C. Bridi et al. Frontiers in Neuroscience
- Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis
- (2018) Craig D. Hughes et al. ACTA NEUROPATHOLOGICA
- Iron chelator deferiprone rescues memory deficits, hippocampal BDNF levels and antioxidant defenses in an experimental model of memory impairment
- (2018) Luisa Azambuja Alcalde et al. BIOMETALS
- The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo
- (2018) Sabine Ulrike Vay et al. Journal of Neuroinflammation
- Vitamin D protects dopaminergic neurons against neuroinflammation and oxidative stress in hemiparkinsonian rats
- (2018) Ludmila A R Lima et al. Journal of Neuroinflammation
- Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs
- (2018) Delphine Charvin et al. NATURE REVIEWS DRUG DISCOVERY
- Microglia Response During Parkinson’s Disease: Alpha-Synuclein Intervention
- (2018) Sara A. Ferreira et al. Frontiers in Cellular Neuroscience
- Microglial TREM2/DAP12 Signaling: A Double-Edged Sword in Neural Diseases
- (2018) Hiroyuki Konishi et al. Frontiers in Cellular Neuroscience
- Inhibition of Phosphodiesterase-4 Reverses Aβ-Induced Memory Impairment by Regulation of HPA Axis Related cAMP Signaling
- (2018) Ying Xu et al. Frontiers in Aging Neuroscience
- Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model
- (2018) Pei Zhou et al. BRAIN BEHAVIOR AND IMMUNITY
- Non-steroidal anti-inflammatory drugs and risk of Parkinson’s disease in the elderly population: a meta-analysis
- (2018) Tahmina Nasrin Poly et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Neuroprotective effects of Astilbin on MPTP-induced Parkinson's disease mice: Glial reaction, α-synuclein expression and oxidative stress
- (2018) Ying-Li Zhu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
- (2018) Richard Gordon et al. Science Translational Medicine
- Role of Microglia TLRs in Neurodegeneration
- (2018) Bernd L. Fiebich et al. Frontiers in Cellular Neuroscience
- CD73-derived adenosine controls inflammation and neurodegeneration by modulating dopamine signalling
- (2018) Fan Meng et al. BRAIN
- The in situ morphology of microglia is highly sensitive to the mode of tissue fixation
- (2017) Bogdan Cătălin et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Microglia in steady state
- (2017) Katrin Kierdorf et al. JOURNAL OF CLINICAL INVESTIGATION
- Microglial activation in Parkinson’s disease using [18F]-FEPPA
- (2017) Christine Ghadery et al. Journal of Neuroinflammation
- Rolipram improves facilitation of contextual fear extinction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease
- (2017) Ken-ichi Kinoshita et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Defining the contribution of neuroinflammation to Parkinson’s disease in humanized immune system mice
- (2017) Gunjan Dhawan Manocha et al. Molecular Neurodegeneration
- Intermittent theta-burst stimulation rescues dopamine-dependent corticostriatal synaptic plasticity and motor behavior in experimental parkinsonism: Possible role of glial activity
- (2017) Fabrizio Cacace et al. MOVEMENT DISORDERS
- Glitazone use associated with reduced risk of Parkinson's disease
- (2017) Brage Brakedal et al. MOVEMENT DISORDERS
- Targeting iron metabolism in drug discovery and delivery
- (2017) Bart J. Crielaard et al. NATURE REVIEWS DRUG DISCOVERY
- Early upregulation of 18-kDa translocator protein in response to acute neurodegenerative damage in TREM2-deficient mice
- (2017) Sara Belloli et al. NEUROBIOLOGY OF AGING
- Treadmill exercise produces neuroprotective effects in a murine model of Parkinson’s disease by regulating the TLR2/MyD88/NF-κB signaling pathway
- (2017) Jung-Hoon Koo et al. NEUROSCIENCE
- Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons
- (2017) Stephen D. Skaper et al. NEUROSCIENTIST
- Microglial phenotypes in Parkinson’s disease and animal models of the disease
- (2017) Valerie Joers et al. PROGRESS IN NEUROBIOLOGY
- An environment-dependent transcriptional network specifies human microglia identity
- (2017) David Gosselin et al. SCIENCE
- Pathological α-synuclein exacerbates the progression of Parkinson’s disease through microglial activation
- (2017) Qiu-Shuang Zhang et al. TOXICOLOGY LETTERS
- Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative Diseases
- (2017) Gyun Jee Song et al. Frontiers in Aging Neuroscience
- Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson’s Disease
- (2017) Sudhakar R. Subramaniam et al. Frontiers in Aging Neuroscience
- Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target
- (2017) Tommaso Cassano et al. Frontiers in Neuroscience
- The phosphodiesterase inhibitor, ibudilast, attenuates neuroinflammation in the MPTP model of Parkinson’s disease
- (2017) Joanna Schwenkgrub et al. PLoS One
- Iron and dopamine: a toxic couple
- (2016) Dominic J. Hare et al. BRAIN
- 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute microgliosis and astrogliosis in the nigrostriatal system but no bioluminescence imaging-detectable alteration in adult neurogenesis
- (2016) Inga B. Fricke et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies
- (2016) Irene López González et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Does Microglial Activation Influence Hippocampal Volume and Neuronal Function in Alzheimer’s Disease and Parkinson’s Disease Dementia?
- (2016) Grazia D. Femminella et al. JOURNAL OF ALZHEIMERS DISEASE
- Vitamin D Treatment Attenuates Neuroinflammation and Dopaminergic Neurodegeneration in an Animal Model of Parkinson’s Disease, Shifting M1 to M2 Microglia Responses
- (2016) Rosa Calvello et al. Journal of Neuroimmune Pharmacology
- Vitamin D3 alters microglia immune activation by an IL-10 dependent SOCS3 mechanism
- (2016) Mandy Boontanrart et al. JOURNAL OF NEUROIMMUNOLOGY
- Repetitive transcranial magnetic stimulation reduces remote apoptotic cell death and inflammation after focal brain injury
- (2016) Valeria Sasso et al. Journal of Neuroinflammation
- Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines
- (2016) Mousumi Ghosh et al. Journal of Neuroinflammation
- Activated brain mast cells contribute to postoperative cognitive dysfunction by evoking microglia activation and neuronal apoptosis
- (2016) Xiang Zhang et al. Journal of Neuroinflammation
- β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease
- (2016) Shreesh Ojha et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Role of Microglia in Neurological Disorders and Their Potentials as a Therapeutic Target
- (2016) Li Du et al. MOLECULAR NEUROBIOLOGY
- Synaptic failure and α-synuclein
- (2016) Laura Calo et al. MOVEMENT DISORDERS
- Structural disorder of monomeric α-synuclein persists in mammalian cells
- (2016) Francois-Xavier Theillet et al. NATURE
- Microglial brain region−dependent diversity and selective regional sensitivities to aging
- (2016) Kathleen Grabert et al. NATURE NEUROSCIENCE
- A polarizing question: do M1 and M2 microglia exist?
- (2016) Richard M Ransohoff NATURE NEUROSCIENCE
- Regulatory Mechanisms of Vitamin D3 on Production of Nitric Oxide and Pro-inflammatory Cytokines in Microglial BV-2 Cells
- (2016) Yevgeny Aster T. Dulla et al. NEUROCHEMICAL RESEARCH
- The Incidence of Parkinson's Disease: A Systematic Review and Meta-Analysis
- (2016) Lauren Hirsch et al. NEUROEPIDEMIOLOGY
- 1,25-Dihydroxyvitamin D3 Facilitates M2 Polarization and Upregulates TLR10 Expression on Human Microglial Cells
- (2016) Rewa Verma et al. NEUROIMMUNOMODULATION
- TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice
- (2016) Teng Jiang et al. NEUROPHARMACOLOGY
- A novel small-molecule agonist of PPAR-γ potentiates an anti-inflammatory M2 glial phenotype
- (2016) Gyun Jee Song et al. NEUROPHARMACOLOGY
- Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice
- (2016) Pavle Matak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ginsenoside Rg1 attenuates motor impairment and neuroinflammation in the MPTP-probenecid-induced parkinsonism mouse model by targeting α-synuclein abnormalities in the substantia nigra
- (2016) Yang Heng et al. TOXICOLOGY LETTERS
- How Does Transcranial Magnetic Stimulation Influence Glial Cells in the Central Nervous System?
- (2016) Carlie L. Cullen et al. Frontiers in Neural Circuits
- Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke
- (2016) Gergely Szalay et al. Nature Communications
- Cannabinoid Type 2 (CB2) Receptors Activation Protects against Oxidative Stress and Neuroinflammation Associated Dopaminergic Neurodegeneration in Rotenone Model of Parkinson's Disease
- (2016) Hayate Javed et al. Frontiers in Neuroscience
- Alpha-Synuclein Oligomers—Neurotoxic Molecules in Parkinson's Disease and Other Lewy Body Disorders
- (2016) Martin Ingelsson Frontiers in Neuroscience
- Call Off the Dog(ma): M1/M2 Polarization Is Concurrent following Traumatic Brain Injury
- (2016) Josh M. Morganti et al. PLoS One
- Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model
- (2016) Sinead Healy et al. Scientific Reports
- Thiazolidinediones and Parkinson Disease: A Cohort Study
- (2015) John G. Connolly et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson’s disease models
- (2015) Qingshan Wang et al. BRAIN
- Roles of microglia in brain development, tissue maintenance and repair
- (2015) Mackenzie A. Michell-Robinson et al. BRAIN
- Microglial M1/M2 polarization and metabolic states
- (2015) Ruben Orihuela et al. BRITISH JOURNAL OF PHARMACOLOGY
- Targeting α-synuclein as a therapeutic strategy for Parkinson’s disease
- (2015) Nada B Lawand et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Immunomodulatory and neuroprotective effects of ginsenoside Rg1 in the MPTP(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) -induced mouse model of Parkinson's disease
- (2015) Ting-ting Zhou et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Neuroprotective effects of piperine on the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease mouse model
- (2015) WEI YANG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Tanshinone I selectively suppresses pro-inflammatory genes expression in activated microglia and prevents nigrostriatal dopaminergic neurodegeneration in a mouse model of Parkinson׳s disease
- (2015) Shaoxia Wang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson’s disease
- (2015) Elvira Valera et al. Journal of Neuroinflammation
- Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke
- (2015) M. Kawabori et al. JOURNAL OF NEUROSCIENCE
- Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial
- (2015) LANCET NEUROLOGY
- Apocyanin, a Microglial NADPH Oxidase Inhibitor Prevents Dopaminergic Neuronal Degeneration in Lipopolysaccharide-Induced Parkinson’s Disease Model
- (2015) Neha Sharma et al. MOLECULAR NEUROBIOLOGY
- NF-κB Upregulates Type 5 Phosphodiesterase in N9 Microglial Cells: Inhibition by Sildenafil and Yonkenafil
- (2015) Siqi Zhao et al. MOLECULAR NEUROBIOLOGY
- Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling
- (2015) Natura Myeku et al. NATURE MEDICINE
- Host microbiota constantly control maturation and function of microglia in the CNS
- (2015) Daniel Erny et al. NATURE NEUROSCIENCE
- P2X7 receptor is critical in α-synuclein–mediated microglial NADPH oxidase activation
- (2015) Tianfang Jiang et al. NEUROBIOLOGY OF AGING
- α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease
- (2015) Byung-Wook Kim et al. NEUROPHARMACOLOGY
- Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1
- (2015) Frank Szulzewsky et al. PLoS One
- α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation
- (2015) Shijun Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alternatively activated microglia and macrophages in the central nervous system
- (2015) Rafael Franco et al. PROGRESS IN NEUROBIOLOGY
- Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders
- (2015) Stefano G. Daniele et al. Science Signaling
- Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study
- (2015) Ruth Brauer et al. PLOS MEDICINE
- Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders
- (2015) Stefano G. Daniele et al. Science Signaling
- Neuroinflammation in Parkinson’s disease and its potential as therapeutic target
- (2015) Qinqin Wang et al. Translational Neurodegeneration
- Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
- (2015) Inge R Holtman et al. Acta Neuropathologica Communications
- CD200R1 and CD200 expression are regulated by PPAR-γ in activated glial cells
- (2014) Guido Dentesano et al. GLIA
- Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases
- (2014) Qingshan Wang et al. GLIA
- Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases
- (2014) Hugo González et al. JOURNAL OF NEUROIMMUNOLOGY
- Brain Injection of -Synuclein Induces Multiple Proteinopathies, Gliosis, and a Neuronal Injury Marker
- (2014) A. N. Sacino et al. JOURNAL OF NEUROSCIENCE
- The role of iron in brain ageing and neurodegenerative disorders
- (2014) Roberta J Ward et al. LANCET NEUROLOGY
- 7 tesla magnetic resonance imaging: A closer look at substantia nigra anatomy in Parkinson's disease
- (2014) Stéphane Lehéricy et al. MOVEMENT DISORDERS
- Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease
- (2014) Augusta Pisanu et al. NEUROBIOLOGY OF DISEASE
- Potential neuroprotective effect of ibuprofen, insights from the mice model of Parkinson's disease
- (2014) Maciej Świątkiewicz et al. Pharmacological Reports
- Effect of human interleukin-10 on the expression of nitric oxide synthases in the MPTP-based model of Parkinson's disease
- (2014) Joanna Schwenkgrub et al. Pharmacological Reports
- The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease
- (2014) Ilona Joniec-Maciejak et al. Pharmacological Reports
- The gut microbiota influences blood-brain barrier permeability in mice
- (2014) V. Braniste et al. Science Translational Medicine
- Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients
- (2014) Karlijn J Doorn et al. Acta Neuropathologica Communications
- Pro-inflammatory cytokines modulate iron regulatory protein 1 expression and iron transportation through reactive oxygen/nitrogen species production in ventral mesencephalic neurons
- (2013) Jia Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro
- (2013) Vibol Chhor et al. BRAIN BEHAVIOR AND IMMUNITY
- Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells
- (2013) Pamela Urrutia et al. JOURNAL OF NEUROCHEMISTRY
- Quantitative assessment of iron deposition in the midbrain using 3D-enhanced T2 star weighted angiography (ESWAN): A preliminary cross-sectional study of 20 Parkinson’s disease patients
- (2013) Ci Wang et al. MAGNETIC RESONANCE IMAGING
- Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation
- (2013) Adam Aguirre et al. MEDIATORS OF INFLAMMATION
- TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease
- (2013) Sruti Rayaprolu et al. Molecular Neurodegeneration
- Characterization of peripheral hematopoietic stem cells and monocytes in Parkinson's disease
- (2013) Natalja Funk et al. MOVEMENT DISORDERS
- Layer V cortical neurons require microglial support for survival during postnatal development
- (2013) Masaki Ueno et al. NATURE NEUROSCIENCE
- M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
- (2013) Veronique E Miron et al. NATURE NEUROSCIENCE
- Neuroinflammation and oxidative stress: Co-conspirators in the pathology of Parkinson’s disease
- (2013) Juliet M. Taylor et al. NEUROCHEMISTRY INTERNATIONAL
- Microglia, Amyloid and Glucose Metabolism in Parkinson’s Disease with and without Dementia
- (2013) Paul Edison et al. NEUROPSYCHOPHARMACOLOGY
- Minocycline selectively inhibits M1 polarization of microglia
- (2013) K Kobayashi et al. Cell Death & Disease
- Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
- (2013) Changyoun Kim et al. Nature Communications
- Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage
- (2013) G. K. Sheridan et al. Open Biology
- Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
- (2012) Lisa Fellner et al. GLIA
- Protosappanin A inhibits oxidative and nitrative stress via interfering the interaction of transmembrane protein CD14 with Toll-like receptor-4 in lipopolysaccharide-induced BV-2 microglia
- (2012) Ke-Wu Zeng et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- CD4+ Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson’s Disease
- (2012) Jessica A. Hutter Saunders et al. Journal of Neuroimmune Pharmacology
- Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
- (2012) Dorothy P. Schafer et al. NEURON
- Review: Activation patterns of microglia and their identification in the human brain
- (2012) D. Boche et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease
- (2012) S. Iannaccone et al. PARKINSONISM & RELATED DISORDERS
- Sildenafil (Viagra) ameliorates clinical symptoms and neuropathology in a mouse model of multiple sclerosis
- (2011) Paula Pifarre et al. ACTA NEUROPATHOLOGICA
- Toll-Like Receptor 4 Promotes α-Synuclein Clearance and Survival of Nigral Dopaminergic Neurons
- (2011) Nadia Stefanova et al. AMERICAN JOURNAL OF PATHOLOGY
- Impaired CD200–CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: Roles of aging, superoxide, NADPH oxidase, and p38 MAPK
- (2011) Xi-Jin Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
- (2011) Christian Hansen et al. JOURNAL OF CLINICAL INVESTIGATION
- Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation
- (2011) Sang-Ho Choi et al. JOURNAL OF NEUROCHEMISTRY
- CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease
- (2011) Shi Zhang et al. Journal of Neuroinflammation
- CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease
- (2011) Mibel M Pabon et al. Journal of Neuroinflammation
- The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys
- (2011) Christine R Swanson et al. Journal of Neuroinflammation
- Surface TLR2 and TLR4 Expression on Mature Rat Mast Cells Can Be Affected by Some Bacterial Components and Proinflammatory Cytokines
- (2011) Anna Pietrzak et al. MEDIATORS OF INFLAMMATION
- Use of ibuprofen and risk of Parkinson disease
- (2011) X. Gao et al. NEUROLOGY
- Neurotoxin-based models of Parkinson's disease
- (2011) J. Bové et al. NEUROSCIENCE
- Physiology of Microglia
- (2011) Helmut Kettenmann et al. PHYSIOLOGICAL REVIEWS
- Evidence for More than One Parkinson's Disease-Associated Variant within the HLA Region
- (2011) Erin M. Hill-Burns et al. PLoS One
- Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
- (2011) R. C. Paolicelli et al. SCIENCE
- Characterizing iron deposition in Parkinson's disease using susceptibility-weighted imaging: An in vivo MR study
- (2010) Jiuquan Zhang et al. BRAIN RESEARCH
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis
- (2010) Amanda Sierra et al. Cell Stem Cell
- -Synuclein Activates Microglia by Inducing the Expressions of Matrix Metalloproteinases and the Subsequent Activation of Protease-Activated Receptor-1
- (2010) E.-J. Lee et al. JOURNAL OF IMMUNOLOGY
- Resveratrol Protects Dopamine Neurons Against Lipopolysaccharide-Induced Neurotoxicity through Its Anti-Inflammatory Actions
- (2010) F. Zhang et al. MOLECULAR PHARMACOLOGY
- Delayed Dominant-Negative TNF Gene Therapy Halts Progressive Loss of Nigral Dopaminergic Neurons in a Rat Model of Parkinson's Disease
- (2010) Ashley S Harms et al. MOLECULAR THERAPY
- Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling
- (2010) Su-Chang Lin et al. NATURE
- Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
- (2010) Taye H Hamza et al. NATURE GENETICS
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- Anti-inflammatory drugs and risk of Parkinson disease: A meta-analysis
- (2010) J. J. Gagne et al. NEUROLOGY
- Accumulation of Non-Transferrin-Bound Iron by Neurons, Astrocytes, and Microglia
- (2010) Glenda M. Bishop et al. NEUROTOXICITY RESEARCH
- Microglial Physiology: Unique Stimuli, Specialized Responses
- (2009) Richard M. Ransohoff et al. Annual Review of Immunology
- NSAID Use and the Risk of Parkinsonʼs Disease
- (2009) Ali Samii et al. DRUGS & AGING
- Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases
- (2009) Xiaoyu Hu et al. IMMUNITY
- Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson’s disease
- (2009) Lilia Marinova-Mutafchieva et al. JOURNAL OF NEUROCHEMISTRY
- Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals
- (2009) H. Wake et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation in Parkinson's disease: a target for neuroprotection?
- (2009) Etienne C Hirsch et al. LANCET NEUROLOGY
- Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention
- (2009) Malú G. Tansey et al. NEUROBIOLOGY OF DISEASE
- Mutant α-Synuclein Overexpression Mediates Early Proinflammatory Activity
- (2009) Xiaomin Su et al. NEUROTOXICITY RESEARCH
- Neuroprotective Effect of Ghrelin in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson’s Disease by Blocking Microglial Activation
- (2009) Minho Moon et al. NEUROTOXICITY RESEARCH
- Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats
- (2009) Amit Gupta et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Candesartan inhibits Toll-like receptor expression and activity both in vitro and in vivo
- (2008) Mohan R. Dasu et al. ATHEROSCLEROSIS
- Debris clearance by microglia: an essential link between degeneration and regeneration
- (2008) H. Neumann et al. BRAIN
- Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra
- (2008) Hong Jiang et al. EXPERIMENTAL NEUROLOGY
- Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway
- (2008) Teresa F Pais et al. Journal of Neuroinflammation
- Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease
- (2008) Shaji Theodore et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Developmental Neuronal Death in Hippocampus Requires the Microglial CD11b Integrin and DAP12 Immunoreceptor
- (2008) S. Wakselman et al. JOURNAL OF NEUROSCIENCE
- Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats
- (2008) Melissa K McCoy et al. MOLECULAR THERAPY
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression
- (2008) Hui-Ming Gao et al. TRENDS IN IMMUNOLOGY
- Inflammation as a causative factor in the aetiology of Parkinson's disease
- (2007) P S Whitton BRITISH JOURNAL OF PHARMACOLOGY
- Synuclein activates microglia in a model of Parkinson's disease
- (2007) Xiaomin Su et al. NEUROBIOLOGY OF AGING
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search