Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and Pathology
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Title
Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and Pathology
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 1, Pages 141
Publisher
MDPI AG
Online
2019-01-03
DOI
10.3390/ijms20010141
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Note: Only part of the references are listed.- Optical Structural Analysis of Individual α-Synuclein Oligomers
- (2018) Juan A. Varela et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Comparative Analysis of the Conformation, Aggregation, Interaction, and Fibril Morphologies of Human α-, β-, and γ-Synuclein Proteins
- (2018) Manish Kumar Jain et al. BIOCHEMISTRY
- Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach
- (2018) Erika Bereczki et al. BRAIN
- Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains
- (2018) Francesca Longhena et al. BRAIN PATHOLOGY
- Release and uptake of pathologic alpha-synuclein
- (2018) Veselin Grozdanov et al. CELL AND TISSUE RESEARCH
- Crucial role of protein oligomerization in the pathogenesis of Alzheimer's and Parkinson's diseases
- (2018) Minee L. Choi et al. FEBS Journal
- Differential effects of 14-3-3 dimers on Tau phosphorylation, stability and toxicity in vivo
- (2018) Katerina Papanikolopoulou et al. HUMAN MOLECULAR GENETICS
- Dopamine Transporter/α-Synuclein Complexes Are Altered in the Post Mortem Caudate Putamen of Parkinson’s Disease: An In Situ Proximity Ligation Assay Study
- (2018) Francesca Longhena et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies
- (2018) Chao Peng et al. NATURE
- Distinct α-Synuclein strains and implications for heterogeneity among α-Synucleinopathies
- (2018) Chao Peng et al. NEUROBIOLOGY OF DISEASE
- The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases
- (2018) Nolwen L. Rey et al. NEUROBIOLOGY OF DISEASE
- α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton
- (2018) Dalila G. Ordonez et al. NEURON
- α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies
- (2018) Iryna Prots et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Detection of amyloid fibrils in Parkinson’s disease using plasmonic chirality
- (2018) Jatish Kumar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction
- (2018) Janin Lautenschläger et al. Nature Communications
- Cryo-EM structure of alpha-synuclein fibrils
- (2018) Ricardo Guerrero-Ferreira et al. eLife
- Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease
- (2018) Jessika C. Bridi et al. Frontiers in Neuroscience
- Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease
- (2018) Gaia Faustini et al. ACTA NEUROPATHOLOGICA
- Nuclear localization and phosphorylation modulate pathological effects of Alpha-Synuclein
- (2018) Raquel Pinho et al. HUMAN MOLECULAR GENETICS
- 14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein
- (2018) Bing Wang et al. JOURNAL OF NEUROSCIENCE
- Extreme disorder in an ultrahigh-affinity protein complex
- (2018) Alessandro Borgia et al. NATURE
- Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel
- (2018) Binsen Li et al. Nature Communications
- Membrane binding, internalization, and sorting of alpha-synuclein in the cell
- (2018) Caterina Masaracchia et al. Acta Neuropathologica Communications
- Light at the End of the Amyloid Tunnel
- (2018) Dennis J. Selkoe BIOCHEMISTRY
- In-Cell NMR Spectroscopy of Intrinsically Disordered Proteins
- (2018) Nicholas Sciolino et al. PROTEOMICS
- Mitochondrial Dysregulation and Impaired Autophagy in iPSC-Derived Dopaminergic Neurons of Multiple System Atrophy
- (2018) Giacomo Monzio Compagnoni et al. Stem Cell Reports
- Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy
- (2017) Jessica D. Flynn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held
- (2017) Kohgaku Eguchi et al. JOURNAL OF NEUROSCIENCE
- Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons
- (2017) Federica Bono et al. MOLECULAR NEUROBIOLOGY
- Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons
- (2017) Laura Urrea et al. MOLECULAR NEUROBIOLOGY
- Neuropathology of genetic synucleinopathies with parkinsonism: Review of the literature
- (2017) Susanne A. Schneider et al. MOVEMENT DISORDERS
- α-Synuclein promotes dilation of the exocytotic fusion pore
- (2017) Todd Logan et al. NATURE NEUROSCIENCE
- Bacterial co-expression of human Tau protein with protein kinase A and 14-3-3 for studies of 14-3-3/phospho-Tau interaction
- (2017) Kristina V. Tugaeva et al. PLoS One
- Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease
- (2017) Amy R. Dunn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits
- (2017) Megan E. Larson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson’s disease
- (2017) Georgia Kouroupi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rab GTPases: The Key Players in the Molecular Pathway of Parkinson’s Disease
- (2017) Meng-meng Shi et al. Frontiers in Cellular Neuroscience
- α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling
- (2017) Audrey T. Medeiros et al. Frontiers in Cellular Neuroscience
- Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson’s disease
- (2017) Jenny-Ann Phan et al. Scientific Reports
- Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport
- (2017) Shiori Toba et al. Scientific Reports
- Synucleins Have Multiple Effects on Presynaptic Architecture
- (2017) Karina J. Vargas et al. Cell Reports
- Cell Biology and Pathophysiology of α-Synuclein
- (2017) Jacqueline Burré et al. Cold Spring Harbor Perspectives in Medicine
- Neuropathological Staging of Brain Pathology in Sporadic Parkinson’s disease: Separating the Wheat from the Chaff
- (2017) Heiko Braak et al. Journal of Parkinsons Disease
- The Synucleinopathies: Twenty Years On
- (2017) Michel Goedert et al. Journal of Parkinsons Disease
- The Role of Lipids Interacting with α-Synuclein in the Pathogenesis of Parkinson’s Disease
- (2017) Céline Galvagnion Journal of Parkinsons Disease
- The Contribution ofα-Synuclein Spreading to Parkinson’s Disease Synaptopathy
- (2017) Francesca Longhena et al. NEURAL PLASTICITY
- The Role of Co-chaperones in Synaptic Proteostasis and Neurodegenerative Disease
- (2017) Erica L. Gorenberg et al. Frontiers in Neuroscience
- Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson’s disease
- (2017) Fang Fang et al. Scientific Reports
- Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia
- (2016) Erika Bereczki et al. Alzheimers & Dementia
- Effect of acidic pH on the stability of α-synuclein dimers
- (2016) Zhengjian Lv et al. BIOPOLYMERS
- Exocytosis and Spreading of Normal and Aberrant α-Synuclein
- (2016) Evangelia Emmanouilidou et al. BRAIN PATHOLOGY
- Alpha-synuclein contributes to malignant progression of human meningioma via the Akt/mTOR pathway
- (2016) Yiqin Ge et al. Cancer Cell International
- How strong is the evidence that Parkinsonʼs disease is a prion disorder?
- (2016) Patrik Brundin et al. CURRENT OPINION IN NEUROLOGY
- Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease
- (2016) Nolwen L. Rey et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Exploring the Transition of Human α-Synuclein from Native to the Fibrillar State: Insights into the Pathogenesis of Parkinson’s Disease
- (2016) Naveed Ahmad Fazili et al. JOURNAL OF FLUORESCENCE
- Rab7 induces clearance of α-synuclein aggregates
- (2016) Elisabeth Dinter et al. JOURNAL OF NEUROCHEMISTRY
- X-ray Crystallographic Structure of Oligomers Formed by a Toxic β-Hairpin Derived from α-Synuclein: Trimers and Higher-Order Oligomers
- (2016) Patrick J. Salveson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Microtubule Destabilization Paves the Way to Parkinson’s Disease
- (2016) D. Cartelli et al. MOLECULAR NEUROBIOLOGY
- Synaptic failure and α-synuclein
- (2016) Laura Calo et al. MOVEMENT DISORDERS
- Structural disorder of monomeric α-synuclein persists in mammalian cells
- (2016) Francois-Xavier Theillet et al. NATURE
- α-synuclein folds: the cards are on the table
- (2016) Wouter Peelaerts et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Dynamic structural flexibility of α-synuclein
- (2016) Danielle E. Mor et al. NEUROBIOLOGY OF DISEASE
- Review: Parkinson's disease: from synaptic loss to connectome dysfunction
- (2016) Arianna Bellucci et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Pathological -synuclein transmission initiated by binding lymphocyte-activation gene 3
- (2016) X. Mao et al. SCIENCE
- Structural basis of synaptic vesicle assembly promoted by α-synuclein
- (2016) Giuliana Fusco et al. Nature Communications
- α-synuclein folds: the cards are on the table
- (2016) Wouter Peelaerts et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson’s disease
- (2016) Youssra K. Al-Hilaly et al. Scientific Reports
- shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity
- (2016) Susana A. Gonçalves et al. PLoS Genetics
- α-Synuclein is a Novel Microtubule Dynamase
- (2016) Daniele Cartelli et al. Scientific Reports
- β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces
- (2016) James W. P. Brown et al. Scientific Reports
- Molecular Determinants of α-Synuclein Mutants’ Oligomerization and Membrane Interactions
- (2015) Igor F. Tsigelny et al. ACS Chemical Neuroscience
- Noradrenergic and serotonergic neurochemistry arising from intranasal inoculation with α-synuclein aggregates which incite parkinsonian-like symptoms
- (2015) Marina A. Gruden et al. BEHAVIOURAL BRAIN RESEARCH
- A novel link between the conformations, exposure of specific epitopes, and subcellular localization of α-synuclein
- (2015) Min-Kyung Nam et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- -synuclein assemblies sequester neuronal 3-Na+/K+-ATPase and impair Na+ gradient
- (2015) A. N. Shrivastava et al. EMBO JOURNAL
- Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau
- (2015) Yuyoung Joo et al. FASEB JOURNAL
- Dopamine Transporter Activity Is Modulated by α-Synuclein
- (2015) Brittany Butler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- -synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons
- (2015) M. Zaltieri et al. JOURNAL OF CELL SCIENCE
- Serotonergic dysfunction in the A53T alpha-synuclein mouse model of Parkinson's disease
- (2015) Janina Deusser et al. JOURNAL OF NEUROCHEMISTRY
- Effects of Mutations on the Reconfiguration Rate of α-Synuclein
- (2015) Srabasti Acharya et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Elucidating the Role of Site-Specific Nitration of α-Synuclein in the Pathogenesis of Parkinson’s Disease via Protein Semisynthesis and Mutagenesis
- (2015) Ritwik Burai et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A new role for α-synuclein in Parkinson's disease: Alteration of ER-mitochondrial communication
- (2015) Cristina Guardia-Laguarta et al. MOVEMENT DISORDERS
- Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
- (2015) Céline Galvagnion et al. Nature Chemical Biology
- Effects of impaired membrane interactions on α-synuclein aggregation and neurotoxicity
- (2015) Daniel Ysselstein et al. NEUROBIOLOGY OF DISEASE
- Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration
- (2015) Katrina L. Paumier et al. NEUROBIOLOGY OF DISEASE
- Propagation of prions causing synucleinopathies in cultured cells
- (2015) Amanda L. Woerman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
- (2015) Stanley B. Prusiner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transient misfolding dominates multidomain protein folding
- (2015) Alessandro Borgia et al. Nature Communications
- Novel subcellular localization for α-synuclein: possible functional consequences
- (2015) Cristina Guardia-Laguarta et al. Frontiers in Neuroanatomy
- Unveiling transient protein-protein interactions that modulate inhibition of alpha-synuclein aggregation by beta-synuclein, a pre-synaptic protein that co-localizes with alpha-synuclein
- (2015) Maria K. Janowska et al. Scientific Reports
- The Synaptic Function of α-Synuclein
- (2015) Jacqueline Burré Journal of Parkinsons Disease
- Identification of Synaptosomal Proteins Binding to Monomeric and Oligomeric α-Synuclein
- (2015) Cristine Betzer et al. PLoS One
- Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson’s Disease
- (2015) Anke A. Dijkstra et al. PLoS One
- Nonaggregated α-Synuclein Influences SNARE-Dependent Vesicle Docking via Membrane Binding
- (2014) Ying Lai et al. BIOCHEMISTRY
- Purification of α-Synuclein from Human Brain Reveals an Instability of Endogenous Multimers as the Protein Approaches Purity
- (2014) Eric S. Luth et al. BIOCHEMISTRY
- Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo
- (2014) Edward Rockenstein et al. BRAIN
- Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates
- (2014) E-J Bae et al. CELL DEATH AND DIFFERENTIATION
- α-Synuclein is Prone to Interaction with the GC-Box-Like Sequence In Vitro
- (2014) Kai-Li Ma et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling
- (2014) Lina Wang et al. CURRENT BIOLOGY
- The small GTPase Rab11 co-localizes with -synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity
- (2014) O. Chutna et al. HUMAN MOLECULAR GENETICS
- The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity
- (2014) Nicoletta Plotegher et al. HUMAN MOLECULAR GENETICS
- Linking alpha-synuclein properties with oxidation: a hypothesis on a mechanism underling cellular aggregation
- (2014) Suzanne Scarlata et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Evidence of Native α-Synuclein Conformers in the Human Brain
- (2014) Neal Gould et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synucleins Regulate the Kinetics of Synaptic Vesicle Endocytosis
- (2014) K. J. Vargas et al. JOURNAL OF NEUROSCIENCE
- Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells
- (2014) Rita Perfeito et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The amyloid state and its association with protein misfolding diseases
- (2014) Tuomas P. J. Knowles et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Chaperone-Like Activity of α-Synuclein Attenuates Aggregation of Its Alternatively Spliced Isoform, 112-Synuclein In Vitro: Plausible Cross-Talk between Isoforms in Protein Aggregation
- (2014) Krishna Madhuri Manda et al. PLoS One
- α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation
- (2014) Jacqueline Burré et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Solution conditions determine the relative importance of nucleation and growth processes in -synuclein aggregation
- (2014) A. K. Buell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alpha-synuclein spreading in Parkinson’s disease
- (2014) Ariadna Recasens et al. Frontiers in Neuroanatomy
- Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation
- (2014) Diana F. Lázaro et al. PLoS Genetics
- Evolutionary aspects of the synuclein super-family and sub-families based on large-scale phylogenetic and group-discrimination analysis
- (2013) Jiawen Yuan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- α-Synuclein Oligomers Impair Neuronal Microtubule-Kinesin Interplay
- (2013) Iryna Prots et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In VivoCross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells
- (2013) Ulf Dettmer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-terminal Acetylation Stabilizes N-terminal Helicity in Lipid- and Micelle-bound α-Synuclein and Increases Its Affinity for Physiological Membranes
- (2013) Igor Dikiy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein Overexpression Represses 14-3-3θ Transcription
- (2013) Huiping Ding et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- The Clathrin-Dependent Localization of Dopamine Transporter to Surface Membranes Is Affected by α-Synuclein
- (2013) Haya Kisos et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Dopamine Transporter Endocytic Trafficking in Striatal Dopaminergic Neurons: Differential Dependence on Dynamin and the Actin Cytoskeleton
- (2013) L. R. Gabriel et al. JOURNAL OF NEUROSCIENCE
- The Dynamic Structure of α-Synuclein Multimers
- (2013) Thomas Gurry et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion-Like Disorder?
- (2013) C. Warren Olanow et al. MOVEMENT DISORDERS
- Large -synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking
- (2013) B.-K. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The remarkable conformational plasticity of alpha-synuclein: blessing or curse?
- (2013) Angélique Deleersnijder et al. TRENDS IN MOLECULAR MEDICINE
- Structural and functional characterization of two alpha-synuclein strains
- (2013) Luc Bousset et al. Nature Communications
- Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
- (2013) Jiajie Diao et al. eLife
- Molecular chaperones and protein folding as therapeutic targets in Parkinson’s disease and other synucleinopathies
- (2013) Darius Ebrahimi-Fakhari et al. Acta Neuropathologica Communications
- Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity
- (2012) Meret Nora Gaugler et al. ACTA NEUROPATHOLOGICA
- The Rab family of proteins: 25 years on
- (2012) Eoin E. Kelly et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Alterations in axonal transport motor proteins in sporadic and experimental Parkinson’s disease
- (2012) Yaping Chu et al. BRAIN
- Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
- (2012) Nunilo Cremades et al. CELL
- α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, andEscherichia coliExists Predominantly as Disordered Monomer
- (2012) Bruno Fauvet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Dysfunction of the locus coeruleus-norepinephrine system and related circuitry in Parkinson's disease-related dementia
- (2012) K. Del Tredici et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Accumulation of Toxic -Synuclein Oligomer within Endoplasmic Reticulum Occurs in -Synucleinopathy In Vivo
- (2012) E. Colla et al. JOURNAL OF NEUROSCIENCE
- -Synuclein Inhibits Intersynaptic Vesicle Mobility and Maintains Recycling-Pool Homeostasis
- (2012) D. Scott et al. JOURNAL OF NEUROSCIENCE
- Covalent α-Synuclein Dimers: Chemico-Physical and Aggregation Properties
- (2012) Micaela Pivato et al. PLoS One
- N-terminal acetylation is critical for forming α-helical oligomer of α-synuclein
- (2012) Adam J. Trexler et al. PROTEIN SCIENCE
- Folding and misfolding of alpha-synuclein on membranes
- (2011) Igor Dikiy et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- α-Synuclein misfolding and Parkinson's disease
- (2011) Leonid Breydo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Decreased reuptake of dopamine in the dorsal striatum in the absence of alpha-synuclein
- (2011) Heramb Chadchankar et al. BRAIN RESEARCH
- Hyperphosphorylated Tau in an α-synuclein-overexpressing transgenic model of Parkinson’s disease
- (2011) Thomas Haggerty et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Intrinsically disordered proteins from A to Z
- (2011) Vladimir N. Uversky INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- α-Synuclein Stimulates a Dopamine Transporter-dependent Chloride Current and Modulates the Activity of the Transporter
- (2011) Jarod Swant et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metastability of Native Proteins and the Phenomenon of Amyloid Formation
- (2011) Andrew J. Baldwin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Allostery in a Disordered Protein: Oxidative Modifications to α-Synuclein Act Distally To Regulate Membrane Binding
- (2011) Eva Sevcsik et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
- (2011) Tim Bartels et al. NATURE
- Molecular chaperones in protein folding and proteostasis
- (2011) F. Ulrich Hartl et al. NATURE
- α-Synuclein Expression Selectively Affects Tumorigenesis in Mice Modeling Parkinson's Disease
- (2011) Eitan Israeli et al. PLoS One
- Redistribution of DAT/α-Synuclein Complexes Visualized by “In Situ” Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease
- (2011) Arianna Bellucci et al. PLoS One
- The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia
- (2010) Walter J. Schulz-Schaeffer ACTA NEUROPATHOLOGICA
- SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease
- (2010) Pablo Garcia-Reitböck et al. BRAIN
- Parkinsonian Neurotoxin 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and α-Synuclein Mutations Promote Tau Protein Phosphorylation at Ser262and Destabilize Microtubule Cytoskeletonin Vitro
- (2010) Hamid Y. Qureshi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synapsins Differentially Control Dopamine and Serotonin Release
- (2010) B. M. Kile et al. JOURNAL OF NEUROSCIENCE
- A Pathologic Cascade Leading to Synaptic Dysfunction in -Synuclein-Induced Neurodegeneration
- (2010) D. A. Scott et al. JOURNAL OF NEUROSCIENCE
- Characterization of kinases involved in the phosphorylation of aggregated α-synuclein
- (2010) Elisa A. Waxman et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Are synucleinopathies prion-like disorders?
- (2010) Elodie Angot et al. LANCET NEUROLOGY
- Differential subcellular distribution of endosomal compartments and the dopamine transporter in dopaminergic neurons
- (2010) Anjali Rao et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- α-Synuclein Delays Endoplasmic Reticulum (ER)-to-Golgi Transport in Mammalian Cells by Antagonizing ER/Golgi SNAREs
- (2010) Nandhakumar Thayanidhi et al. MOLECULAR BIOLOGY OF THE CELL
- Dynamic transport and localization of alpha-synuclein in primary hippocampal neurons
- (2010) Mong-Lin Yang et al. Molecular Neurodegeneration
- Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
- (2010) Venu M. Nemani et al. NEURON
- The n-terminal 5-MER peptide analogue P165 of amyloid precursor protein exerts protective effects on SH-SY5Y cells and rat hippocampus neuronal synapses
- (2010) P. Wang et al. NEUROSCIENCE
- Parkinson's Disease-Related Protein, α-Synuclein, in Malignant Melanoma
- (2010) Yasuhiro Matsuo et al. PLoS One
- Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis
- (2010) K. Mukherjee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The synapsins: Key actors of synapse function and plasticity
- (2010) F. Cesca et al. PROGRESS IN NEUROBIOLOGY
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease
- (2010) T A Yacoubian et al. Cell Death & Disease
- Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3ζ protein
- (2009) Golam Sadik et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson’s Disease Revealed by Solution NMR Spectroscopy
- (2009) Christina R. Bodner et al. BIOCHEMISTRY
- α-Synuclein contributes to GSK-3β-catalyzed Tau phosphorylation in Parkinson’s disease models
- (2009) Tetyana Duka et al. FASEB JOURNAL
- Phosphorylation of more than one site is required for tight interaction of human tau protein with 14-3-3ζ
- (2009) Nikolai N. Sluchanko et al. FEBS LETTERS
- Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon
- (2009) Anna Fejtova et al. JOURNAL OF CELL BIOLOGY
- The First N-terminal Amino Acids of α-Synuclein Are Essential for α-Helical Structure Formation In Vitro and Membrane Binding in Yeast
- (2009) Katherina Vamvaca et al. JOURNAL OF MOLECULAR BIOLOGY
- Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV -Synucleinopathy
- (2009) C. Y. Chung et al. JOURNAL OF NEUROSCIENCE
- α-Synuclein and Its A30P Mutant Affect Actin Cytoskeletal Structure and Dynamics
- (2009) Vítor L. Sousa et al. MOLECULAR BIOLOGY OF THE CELL
- Molecular interaction of α-synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells
- (2009) R. M. Zhou et al. MOLECULAR BIOLOGY REPORTS
- PINK1 Defect Causes Mitochondrial Dysfunction, Proteasomal Deficit and α-Synuclein Aggregation in Cell Culture Models of Parkinson's Disease
- (2009) Wencheng Liu et al. PLoS One
- Mitochondrial translocation of α-synuclein is promoted by intracellular acidification
- (2008) Nelson B. Cole et al. EXPERIMENTAL CELL RESEARCH
- Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain
- (2008) Latha Devi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation at Ser-129 but Not the Phosphomimics S129E/D Inhibits the Fibrillation of α-Synuclein
- (2008) Katerina E. Paleologou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2D3receptor activation
- (2008) Arianna Bellucci et al. JOURNAL OF NEUROCHEMISTRY
- Optical Reporters for the Conformation of -Synuclein Reveal a Specific Interaction with Mitochondria
- (2008) K. Nakamura et al. JOURNAL OF NEUROSCIENCE
- Proteomics Analysis Identifies Phosphorylation-dependent α-Synuclein Protein Interactions
- (2008) Melinda A. McFarland et al. MOLECULAR & CELLULAR PROTEOMICS
- Transplanted dopaminergic neurons develop PD pathologic changes: A second case report
- (2008) Jeffrey H. Kordower et al. MOVEMENT DISORDERS
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
- Desipramine Modulation of α-, γ-Synuclein and the Norepinephrine Transporter in an Animal Model of Depression
- (2008) Alexis M Jeannotte et al. NEUROPSYCHOPHARMACOLOGY
- Proteomics ofCaenorhabditis elegans over-expressing humanα-synuclein analyzed by fluorogenic derivatization–liquid chromatography/tandem mass spectrometry: identification of actin and several ribosomal proteins as negative markers at early Parkinson's disease stages
- (2007) Tomoko Ichibangase et al. BIOMEDICAL CHROMATOGRAPHY
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