Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
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Title
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
Authors
Keywords
Amyotrophic Lateral Sclerosis, Primed Microglia, Module Membership, rTg4510 Mouse, Consensus Network
Journal
Acta Neuropathologica Communications
Volume 3, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-05-22
DOI
10.1186/s40478-015-0203-5
References
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Note: Only part of the references are listed.- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Unifying immunology with informatics and multiscale biology
- (2014) Brian A Kidd et al. NATURE IMMUNOLOGY
- Diversification of TAM receptor tyrosine kinase function
- (2014) Anna Zagórska et al. NATURE IMMUNOLOGY
- Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors
- (2014) Andrea Crotti et al. NATURE NEUROSCIENCE
- Microglial priming in neurodegenerative disease
- (2014) V. Hugh Perry et al. Nature Reviews Neurology
- Priming of microglia in a DNA-repair deficient model of accelerated aging
- (2014) Divya D.A. Raj et al. NEUROBIOLOGY OF AGING
- Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
- (2014) Monica R.P. Elmore et al. NEURON
- Aging-induced type I interferon response at the choroid plexus negatively affects brain function
- (2014) K. Baruch et al. SCIENCE
- Integrated multi-cohort transcriptional meta-analysis of neurodegenerative diseases
- (2014) Matthew D Li et al. Acta Neuropathologica Communications
- Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences
- (2013) F. O. Martinez et al. BLOOD
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- SPARC Regulates Microgliosis and Functional Recovery following Cortical Ischemia
- (2013) S. M. Lloyd-Burton et al. JOURNAL OF NEUROSCIENCE
- Regulation of Microglial Proliferation during Chronic Neurodegeneration
- (2013) D. Gomez-Nicola et al. JOURNAL OF NEUROSCIENCE
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- The microglial sensome revealed by direct RNA sequencing
- (2013) Suzanne E Hickman et al. NATURE NEUROSCIENCE
- Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice
- (2013) Marie Orre et al. NEUROBIOLOGY OF AGING
- WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013
- (2013) Jing Wang et al. NUCLEIC ACIDS RESEARCH
- When Is Hub Gene Selection Better than Standard Meta-Analysis?
- (2013) Peter Langfelder et al. PLoS One
- A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
- (2013) Isaac M. Chiu et al. Cell Reports
- Genes and pathways underlying regional and cell type changes in Alzheimer's disease
- (2013) Jeremy A Miller et al. Genome Medicine
- Microglia and neurodegeneration: The role of systemic inflammation
- (2012) Colm Cunningham GLIA
- Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
- (2012) David H Cribbs et al. Journal of Neuroinflammation
- Galectin-3 Is Required for Resident Microglia Activation and Proliferation in Response to Ischemic Injury
- (2012) M. Lalancette-Hebert et al. JOURNAL OF NEUROSCIENCE
- An anatomically comprehensive atlas of the adult human brain transcriptome
- (2012) Michael J. Hawrylycz et al. NATURE
- Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer's disease mouse model
- (2012) Kerstin T.S. Wirz et al. NEUROBIOLOGY OF AGING
- Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
- (2012) Dorothy P. Schafer et al. NEURON
- Review: Activation patterns of microglia and their identification in the human brain
- (2012) D. Boche et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Phagocytic Clearance in Neurodegeneration
- (2011) Jennifer D. Sokolowski et al. AMERICAN JOURNAL OF PATHOLOGY
- Strategies for aggregating gene expression data: The collapseRows R function
- (2011) Jeremy A Miller et al. BMC BIOINFORMATICS
- CX3CR1 Protein Signaling Modulates Microglial Activation and Protects against Plaque-independent Cognitive Deficits in a Mouse Model of Alzheimer Disease
- (2011) Seo-Hyun Cho et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Systemic Inflammation Modulates Fc Receptor Expression on Microglia during Chronic Neurodegeneration
- (2011) K. Lunnon et al. JOURNAL OF IMMUNOLOGY
- Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis
- (2011) Jason G Weinger et al. Journal of Neuroinflammation
- Physiology of Microglia
- (2011) Helmut Kettenmann et al. PHYSIOLOGICAL REVIEWS
- The effects of aging vs. α7 nAChR subunit deficiency on the mouse brain transcriptome: aging beats the deficiency
- (2010) Merav Kedmi et al. AGE
- NeatMap - non-clustering heat map alternatives in R
- (2010) Satwik Rajaram et al. BMC BIOINFORMATICS
- Comprehensive analysis of TLR4-induced transcriptional responses in interleukin 4-primed mouse macrophages
- (2010) Carol El Chartouni et al. IMMUNOBIOLOGY
- Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury
- (2010) Charu Venkatesan et al. Journal of Neuroinflammation
- Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
- (2010) Martin Fuhrmann et al. NATURE NEUROSCIENCE
- Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways
- (2010) Jeremy A. Miller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Up-Regulation of Soluble Axl and Mer Receptor Tyrosine Kinases Negatively Correlates with Gas6 in Established Multiple Sclerosis Lesions
- (2009) Jason G. Weinger et al. AMERICAN JOURNAL OF PATHOLOGY
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Reviews: Mechanisms Mediating Brain Plasticity: IGF1 and Adult Hippocampal Neurogenesis
- (2009) María LLorens-Martín et al. NEUROSCIENTIST
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- Axl−/− mice have delayed recovery and prolonged axonal damage following cuprizone toxicity
- (2008) Hannah J. Hoehn et al. BRAIN RESEARCH
- Role of CX3CR1 (Fractalkine Receptor) in Brain Damage and Inflammation Induced by Focal Cerebral Ischemia in Mouse
- (2008) Ádám Dénes et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Microglial Dysfunction and Defective -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
- (2008) S. E. Hickman et al. JOURNAL OF NEUROSCIENCE
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