Indomethacin promotes survival of new neurons in the adult murine hippocampus accompanied by anti-inflammatory effects following MPTP-induced dopamine depletion

Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation

(2017) Meetu Wadhwa et al.   Journal of Neuroinflammation

Defining the contribution of neuroinflammation to Parkinson’s disease in humanized immune system mice

(2017) Gunjan Dhawan Manocha et al.   Molecular Neurodegeneration

GPER Agonist G1 Attenuates Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson Disease

(2017) Jing Guan et al.   NEUROIMMUNOMODULATION

Berberine attenuates cognitive impairment and ameliorates tau hyperphosphorylation by limiting the self-perpetuating pathogenic cycle between NF-κB signaling, oxidative stress and neuroinflammation

(2017) Wenbo He et al.   Pharmacological Reports

Physical exercise counteracts MPTP-induced changes in neural precursor cell proliferation in the hippocampus and restores spatial learning but not memory performance in the water maze

(2016) C. Klein et al.   BEHAVIOURAL BRAIN RESEARCH

Chronic peripheral inflammation, hippocampal neurogenesis, and behavior

(2016) Vera Chesnokova et al.   BRAIN BEHAVIOR AND IMMUNITY

The Pharmacology of Indomethacin

(2016) Sylvia Lucas   HEADACHE

Indomethacin treatment reduces microglia activation and increases numbers of neuroblasts in the subventricular zone and ischaemic striatum after focal ischaemia

(2016) Rosana S Lopes et al.   JOURNAL OF BIOSCIENCES

CD200 Inhibits Inflammatory Response by Promoting KATP Channel Opening in Microglia Cells in Parkinson’s Disease

(2016) Yi Ren et al.   MEDICAL SCIENCE MONITOR

Gender Differences in the Neurobiology of Anxiety: Focus on Adult Hippocampal Neurogenesis

(2016) Alessandra Aparecida Marques et al.   NEURAL PLASTICITY

Alzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and Gamma

(2016) Alexandre Vallée et al.   Frontiers in Neuroscience

Dopaminergic Neurodegeneration in the Mouse Is Associated with Decrease of Viscoelasticity of Substantia Nigra Tissue

(2016) Elisabeth G. Hain et al.   PLoS One

Thrombin-induced microglial activation impairs hippocampal neurogenesis and spatial memory ability in mice

(2015) Yuan Yang et al.   Behavioral and Brain Functions

Partial depletion of the proinflammatory monocyte population is neuroprotective in the myenteric plexus but not in the basal ganglia in a MPTP mouse model of Parkinson’s disease

(2015) M. Côté et al.   BRAIN BEHAVIOR AND IMMUNITY

Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of α-synuclein

(2015) Johannes C.M. Schlachetzki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effects of treadmill exercise on hippocampal neurogenesis in an MPTP /probenecid-induced Parkinson’s disease mouse model

(2015) Yun-Hee Sung   Journal of Physical Therapy Science

Comparison of pharmacological and genetic inhibition of cyclooxygenase-2: effects on adult neurogenesis in the hippocampal dentate gyrus

(2015) Sung Min Nam et al.   Journal of Veterinary Science

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Long-term treatment with l-DOPA or pramipexole affects adult neurogenesis and corresponding non-motor behavior in a mouse model of Parkinson's disease

(2015) W.-H. Chiu et al.   NEUROPHARMACOLOGY

The role of inflammatory cytokines as key modulators of neurogenesis

(2015) Alessandra Borsini et al.   TRENDS IN NEUROSCIENCES

In vivo imaging of activated microglia in a mouse model of focal cerebral ischemia by two-photon microscopy

(2015) Seoyeon Bok et al.   Biomedical Optics Express

A PPAR-β/δ Agonist is Neuroprotective and Decreases Cognitive Impairment in a Rodent Model of Parkinson’s Disease

(2014) Nihar Das et al.   CURRENT NEUROVASCULAR RESEARCH

Origin of the dopaminergic innervation of adult neurogenic areas

(2014) Günter U. Höglinger et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Current perspectives on the link between neuroinflammation and neurogenesis

(2014) Brian Wang et al.   METABOLIC BRAIN DISEASE

Indomethacin reverses decreased hippocampal cell proliferation in streptozotocin-induced diabetic mice

(2014) Nancy Ho et al.   METABOLIC BRAIN DISEASE

Phagocytosis of Microglia in the Central Nervous System Diseases

(2014) Ruying Fu et al.   MOLECULAR NEUROBIOLOGY

Impact of indomethacin on neuroinflammation and hippocampal neurogenesis in aged mice

(2014) Marcus Boehme et al.   NEUROSCIENCE LETTERS

Enhanced Adult Neurogenesis Increases Brain Stiffness: In Vivo Magnetic Resonance Elastography in a Mouse Model of Dopamine Depletion

(2014) Charlotte Klein et al.   PLoS One

MDMA administration during adolescence exacerbates MPTP-induced cognitive impairment and neuroinflammation in the hippocampus and prefrontal cortex

(2014) Giulia Costa et al.   PSYCHOPHARMACOLOGY

Interleukin-17 inhibits Adult Hippocampal Neurogenesis

(2014) Qiang Liu et al.   Scientific Reports

Hippocampal Proliferation Is Increased in Presymptomatic Parkinson’s Disease and due to Microglia

(2014) Karlijn J. Doorn et al.   NEURAL PLASTICITY

Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis

(2014) Amanda Sierra et al.   NEURAL PLASTICITY

Increased Amoeboid Microglial Density in the Olfactory Bulb of Parkinson's and Alzheimer's Patients

(2013) Karlijn J. Doorn et al.   BRAIN PATHOLOGY

EP2 Receptor Signaling Pathways Regulate Classical Activation of Microglia

(2013) Yi Quan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiproliferative and Apoptotic Effects of Indomethacin on Human Retinoblastoma Cell Line Y79 and the Involvement of ß-Catenin, Nuclear Factor-κB and Akt Signaling Pathways

(2013) Qinxiang Zheng et al.   OPHTHALMIC RESEARCH

Immunopharmacological intervention for successful neural stem cell therapy: New perspectives in CNS neurogenesis and repair

(2013) Dearbhaile Dooley et al.   PHARMACOLOGY & THERAPEUTICS

Modulation of adult-born neurons in the inflamed hippocampus

(2013) Karim Belarbi et al.   Frontiers in Cellular Neuroscience

Physical activity and environmental enrichment regulate the generation of neural precursors in the adult mouse substantia nigra in a dopamine-dependent manner

(2012) Philipp Klaissle et al.   BMC NEUROSCIENCE

MPTP-induced hippocampal effects on serotonin, dopamine, neurotrophins, adult neurogenesis and depression-like behavior are partially influenced by fluoxetine in adult mice

(2012) Anne Lesemann et al.   BRAIN RESEARCH

Sex-dependent differences in behavior and hippocampal neurogenesis after irradiation to the young mouse brain

(2012) Karolina Roughton et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Plasticity of Subventricular Zone Neuroprogenitors in MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) Mouse Model of Parkinson's Disease Involves Cross Talk between Inflammatory and Wnt/ -Catenin Signaling Pathways: Functional Consequences for Neuroprotection and Repair

(2012) F. L'Episcopo et al.   JOURNAL OF NEUROSCIENCE

Sox21 Promotes Hippocampal Adult Neurogenesis via the Transcriptional Repression of the Hes5 Gene

(2012) S. Matsuda et al.   JOURNAL OF NEUROSCIENCE

Microglial Activation – Tuning and Pruning Adult Neurogenesis

(2012) Christine T. Ekdahl   Frontiers in Pharmacology

Opposite effect of inflammation on subventricular zone versus hippocampal precursors in brain injury

(2011) Matthew V. Covey et al.   ANNALS OF NEUROLOGY

The critical role of the MyD88-dependent pathway in non-CNS MPTP-mediated toxicity

(2011) M. Côté et al.   BRAIN BEHAVIOR AND IMMUNITY

AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice

(2011) T Kiyota et al.   GENE THERAPY

Ablation of Cyclooxygenase-2 in Forebrain Neurons is Neuroprotective and Dampens Brain Inflammation after Status Epilepticus

(2011) G. E. Serrano et al.   JOURNAL OF NEUROSCIENCE

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

Neuroinflammation in Parkinson's disease

(2011) Etienne C. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

The Neurogenic Basic Helix-Loop-Helix Transcription Factor NeuroD6 Confers Tolerance to Oxidative Stress by Triggering an Antioxidant Response and Sustaining the Mitochondrial Biomass

(2010) Martine Uittenbogaard et al.   ASN Neuro

Reactive microgliosis: extracellular μ-calpain and microglia-mediated dopaminergic neurotoxicity

(2010) Shannon Levesque et al.   BRAIN

Quiescent and Active Hippocampal Neural Stem Cells with Distinct Morphologies Respond Selectively to Physiological and Pathological Stimuli and Aging

(2010) Sebastian Lugert et al.   Cell Stem Cell

Cyclooxygenase and Neuroinflammation in Parkinsons Disease Neurodegeneration

(2010) Anna Bartels et al.   Current Neuropharmacology

Modulation of adult hippocampal neurogenesis during myelin-directed autoimmune neuroinflammation

(2010) Petra Huehnchen et al.   GLIA

Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

(2010) Francesca L'Episcopo et al.   Journal of Neuroinflammation

Gender differences in Parkinson's disease: Clinical characteristics and cognition

(2010) Ivy N. Miller et al.   MOVEMENT DISORDERS

Microglial activation and chronic neurodegeneration

(2010) Melinda E. Lull et al.   Neurotherapeutics

Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration

(2009) Konstantinos Pothakos et al.   BMC NEUROSCIENCE

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

Neuroprotective Effect of PACAP on Translational Control Alteration and Cognitive Decline in MPTP Parkinsonian Mice

(2009) Julie Deguil et al.   NEUROTOXICITY RESEARCH

Peripheral cytokines profile in Parkinson’s disease

(2008) M. Reale et al.   BRAIN BEHAVIOR AND IMMUNITY

The effects of MPTP on the activation of microglia/astrocytes and cytokine/chemokine levels in different mice strains

(2008) Y YASUDA et al.   JOURNAL OF NEUROIMMUNOLOGY

Brain inflammation and adult neurogenesis: The dual role of microglia

(2008) C.T. Ekdahl et al.   NEUROSCIENCE

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS