α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

Cell-Produced  -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

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Are synucleinopathies prion-like disorders?

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Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease

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Prion-like transmission of protein aggregates in neurodegenerative diseases

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 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

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The propagation of prion-like protein inclusions in neurodegenerative diseases

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Lewy body pathology in fetal grafts

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Propagation of Tau Misfolding from the Outside to the Inside of a Cell

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Seeding induced by α-synuclein oligomers provides evidence for spreading of α-synuclein pathology

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Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates

(2009) Pei-Hsien Ren et al.   NATURE CELL BIOLOGY

The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids

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Dissecting the potential molecular mechanisms underlying α-synuclein cell-to-cell transfer in Parkinson's disease

(2009) Elodie Angot et al.   PARKINSONISM & RELATED DISORDERS

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exogenous  -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

(2009) K. C. Luk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly-dependent endocytosis and clearance of extracellular a-synuclein

(2008) He-Jin Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Lrrk2 and α-synuclein are co-regulated in rodent striatum

(2008) Marie Westerlund et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

(2008) Jia-Yi Li et al.   NATURE MEDICINE

Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

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Research in motion: the enigma of Parkinson's disease pathology spread

(2008) Patrik Brundin et al.   NATURE REVIEWS NEUROSCIENCE

Formation of Toxic Oligomeric α-Synuclein Species in Living Cells

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Adapting Proteostasis for Disease Intervention

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