Neuroinflammation in Parkinson’s disease and its potential as therapeutic target
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Title
Neuroinflammation in Parkinson’s disease and its potential as therapeutic target
Authors
Keywords
Parkinson’s disease, Neurodegeneration, Glial cells, Neuroinflammation
Journal
Translational Neurodegeneration
Volume 4, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-10-14
DOI
10.1186/s40035-015-0042-0
References
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Note: Only part of the references are listed.- Potential Role of Aspirin in the Prevention of Aneurysmal Subarachnoid Hemorrhage
- (2015) Robert M. Starke et al. CEREBROVASCULAR DISEASES
- Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases
- (2015) Yu Tang et al. MOLECULAR NEUROBIOLOGY
- Upregulation of alphaB-crystallin expression in the substantia nigra of patients with Parkinson's disease
- (2015) Yingjun Liu et al. NEUROBIOLOGY OF AGING
- Phytic acid attenuates inflammatory responses and the levels of NF-κB and p-ERK in MPTP-induced Parkinson’s disease model of mice
- (2015) Yuqiang Lv et al. NEUROSCIENCE LETTERS
- The association between infectious burden and Parkinson's disease: A case-control study
- (2015) Xian-Le Bu et al. PARKINSONISM & RELATED DISORDERS
- Helicobacter pylori infection is associated with worse severity of Parkinson's disease
- (2015) Ai Huey Tan et al. PARKINSONISM & RELATED DISORDERS
- Activation of Dopamine D2 Receptor Suppresses Neuroinflammation Through αB-Crystalline by Inhibition of NF-κB Nuclear Translocation in Experimental ICH Mice Model
- (2015) Yang Zhang et al. STROKE
- Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurodegeneration
- (2015) Shanshan Cheng et al. Scientific Reports
- Heterogeneous induction of microglia M2a phenotype by central administration of interleukin-4
- (2014) Giovanna Pepe et al. Journal of Neuroinflammation
- The prevalence of Parkinson's disease: A systematic review and meta-analysis
- (2014) Tamara Pringsheim et al. MOVEMENT DISORDERS
- Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease
- (2014) Augusta Pisanu et al. NEUROBIOLOGY OF DISEASE
- Jmjd3 is essential for the epigenetic modulation of microglia phenotypes in the immune pathogenesis of Parkinson’s disease
- (2013) Y Tang et al. CELL DEATH AND DIFFERENTIATION
- Microglia/Macrophage Polarization Dynamics in White Matter after Traumatic Brain Injury
- (2013) Guohua Wang et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline
- (2013) Dorit Trudler et al. JOURNAL OF NEUROCHEMISTRY
- Innate immunity in the Grid2 Lc/+ mouse model of cerebellar neurodegeneration: glial CD95/CD95L plays a non-apoptotic role in persistent neuron loss-associated inflammatory reactions in the cerebellum
- (2013) Béatrice Vernet-der Garabedian et al. Journal of Neuroinflammation
- Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies
- (2013) Gaia Codolo et al. PLoS One
- General Anesthetics Inhibit LPS-Induced IL-1β Expression in Glial Cells
- (2013) Tomoharu Tanaka et al. PLoS One
- Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage
- (2013) G. K. Sheridan et al. Open Biology
- PINK1 Deficiency Enhances Inflammatory Cytokine Release from Acutely Prepared Brain Slices
- (2013) Jun Kim et al. Experimental Neurobiology
- Acacetin Protects Dopaminergic Cells against 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Neuroinflammation in Vitro and in Vivo
- (2012) Hyo Geun Kim et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Vascular Degeneration in Parkinson's Disease
- (2012) Jian Guan et al. BRAIN PATHOLOGY
- Treatment for Helicobacter pylori infection and risk of parkinson’s disease in Denmark
- (2012) H. H. Nielsen et al. EUROPEAN JOURNAL OF NEUROLOGY
- Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein
- (2012) Melanie B. Watson et al. EXPERIMENTAL NEUROLOGY
- Purinergic receptors in microglia: Functional modal shifts of microglia mediated by P2 and P1 receptors
- (2012) Schuichi Koizumi et al. GLIA
- Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
- (2012) Lisa Fellner et al. GLIA
- PINK1 positively regulates IL-1β-mediated signaling through Tollip and IRAK1 modulation
- (2012) Hyun Jung Lee et al. Journal of Neuroinflammation
- The Soluble Isoform of CX3CL1 Is Necessary for Neuroprotection in a Mouse Model of Parkinson's Disease
- (2012) J. M. Morganti et al. JOURNAL OF NEUROSCIENCE
- LRRK2 Inhibition Attenuates Microglial Inflammatory Responses
- (2012) M. S. Moehle et al. JOURNAL OF NEUROSCIENCE
- Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin
- (2012) Wei Shao et al. NATURE
- Acacetin Attenuates Neuroinflammation via Regulation the Response to LPS Stimuli In Vitro and In Vivo
- (2012) Sang Keun Ha et al. NEUROCHEMICAL RESEARCH
- Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity
- (2012) F. Gillardon et al. NEUROSCIENCE
- A Progressive Mouse Model of Parkinson’s Disease: The Thy1-aSyn (“Line 61”) Mice
- (2012) Marie-Francoise Chesselet et al. Neurotherapeutics
- Impaired Inflammatory Responses in Murine Lrrk2-Knockdown Brain Microglia
- (2012) Beomsue Kim et al. PLoS One
- Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia
- (2012) Xiaoming Hu et al. STROKE
- Epidemiology and etiology of Parkinson’s disease: a review of the evidence
- (2011) Karin Wirdefeldt et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Impaired CD200–CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: Roles of aging, superoxide, NADPH oxidase, and p38 MAPK
- (2011) Xi-Jin Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures
- (2011) Mansoureh Hakimi et al. JOURNAL OF NEURAL TRANSMISSION
- Expression of mutant alpha-synuclein modulates microglial phenotype in vitro
- (2011) Lalida Rojanathammanee et al. Journal of Neuroinflammation
- CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease
- (2011) Shi Zhang et al. Journal of Neuroinflammation
- CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease
- (2011) Mibel M Pabon et al. Journal of Neuroinflammation
- The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease
- (2011) Zhihua Liu et al. NATURE IMMUNOLOGY
- Non-Steroidal Anti-Inflammatory Drug Use and the Risk of Parkinson’s Disease
- (2011) Angelika D. Manthripragada et al. NEUROEPIDEMIOLOGY
- Use of ibuprofen and risk of Parkinson disease
- (2011) X. Gao et al. NEUROLOGY
- Neuroinflammation in Parkinson's disease
- (2011) Etienne C. Hirsch et al. PARKINSONISM & RELATED DISORDERS
- Misfolded α-synuclein and toll-like receptors: therapeutic targets for Parkinson's disease
- (2011) Dawn Béraud et al. PARKINSONISM & RELATED DISORDERS
- Increased Mitochondrial Calcium Sensitivity and Abnormal Expression of Innate Immunity Genes Precede Dopaminergic Defects in Pink1-Deficient Mice
- (2011) Ravi S. Akundi et al. PLoS One
- Lipopolysaccharide and Tumor Necrosis Factor Regulate Parkin Expression via Nuclear Factor-Kappa B
- (2011) Thi A. Tran et al. PLoS One
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- LRRK2 Is Involved in the IFN- Response and Host Response to Pathogens
- (2010) A. Gardet et al. JOURNAL OF IMMUNOLOGY
- Ulcerative colitis exacerbates lipopolysaccharide-induced damage to the nigral dopaminergic system: potential risk factor in Parkinson`s disease
- (2010) Ruth F. Villarán et al. JOURNAL OF NEUROCHEMISTRY
- Delayed Dominant-Negative TNF Gene Therapy Halts Progressive Loss of Nigral Dopaminergic Neurons in a Rat Model of Parkinson's Disease
- (2010) Ashley S Harms et al. MOLECULAR THERAPY
- Anti-inflammatory drugs and risk of Parkinson disease: A meta-analysis
- (2010) J. J. Gagne et al. NEUROLOGY
- Minocycline as a potential therapeutic agent in neurodegenerative disorders characterized by protein misfolding
- (2010) Wendy Noble et al. Prion
- Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice
- (2010) Xing-Long Gu et al. Molecular Brain
- Naloxone-responsive acute dystonia and parkinsonism following general anaesthesia
- (2009) I. A. Iselin-Chaves et al. ANAESTHESIA
- A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death
- (2009) Kaoru Saijo et al. CELL
- Regulation of astrocyte inflammatory responses by the Parkinson’s disease-associated gene DJ-1
- (2009) Jens Waak et al. FASEB JOURNAL
- Neuroinflammation in Parkinson's disease: a target for neuroprotection?
- (2009) Etienne C Hirsch et al. LANCET NEUROLOGY
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- [11C]-PK11195 PET: Quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson's disease?
- (2009) A.L. Bartels et al. PARKINSONISM & RELATED DISORDERS
- Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease
- (2008) Shaji Theodore et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration
- (2008) T. C. Frank-Cannon et al. JOURNAL OF NEUROSCIENCE
- Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats
- (2008) Melissa K McCoy et al. MOLECULAR THERAPY
- Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
- (2008) Eric J. Benner et al. PLoS One
- Synuclein activates microglia in a model of Parkinson's disease
- (2007) Xiaomin Su et al. NEUROBIOLOGY OF AGING
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