β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease

β-Caryophyllene alleviates d-galactosamine and lipopolysaccharide-induced hepatic injury through suppression of the TLR4 and RAGE signaling pathways

(2015) Hong-Ik Cho et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Understanding Parkinson Disease

(2015) Apoorva Gopalakrishna et al.   JOURNAL OF NEUROSCIENCE NURSING

Histopathological and electrophysiological indices of rotenone-evoked dopaminergic toxicity: Neuroprotective effects of acetyl-l-carnitine

(2015) S. Sarkar et al.   NEUROSCIENCE LETTERS

Trans-Caryophyllene Suppresses Hypoxia-Induced Neuroinflammatory Responses by Inhibiting NF-κB Activation in Microglia

(2014) Kexin Guo et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Antigenotoxic capacity of beta-caryophyllene in mouse, and evaluation of its antioxidant and GST induction activities

(2014) Isela Álvarez-González et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Neuroprotective Effects of Trans-Caryophyllene Against Kainic Acid Induced Seizure Activity and Oxidative Stress in Mice

(2014) Hao Liu et al.   NEUROCHEMICAL RESEARCH

β-Caryophyllene protects the C6 glioma cells against glutamate-induced excitotoxicity through the Nrf2 pathway

(2014) L.C. Assis et al.   NEUROSCIENCE

�-Caryophyllene Ameliorates the Alzheimer-Like Phenotype in APP/PS1 Mice through CB2 Receptor Activation and the PPARγ Pathway

(2014) Yujie Cheng et al.   PHARMACOLOGY

The cannabinoid receptor 2 agonist, β-caryophyllene, reduced voluntary alcohol intake and attenuated ethanol-induced place preference and sensitivity in mice

(2014) Shamma Al Mansouri et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The emerging role of nutrition in Parkinson's disease

(2014) Stacey E. Seidl et al.   Frontiers in Aging Neuroscience

Activation of Cannabinoid CB2 Receptor–Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury

(2013) In-Young Choi et al.   AMERICAN JOURNAL OF PATHOLOGY

Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1α pathway

(2013) Xuqin Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

(2013) Huajun Jin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

β-Caryophyllene causes regression of endometrial implants in a rat model of endometriosis without affecting fertility

(2013) Manal A. Abbas et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glutathione metabolism and Parkinson's disease

(2013) Michelle Smeyne et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Role of Inflammatory and Oxidative Stress Mechanisms in the Pathogenesis of Parkinson’s Disease: Focus on Astrocytes

(2013) Rituraj Niranjan   MOLECULAR NEUROBIOLOGY

Neuroinflammation and oxidative stress: Co-conspirators in the pathology of Parkinson’s disease

(2013) Juliet M. Taylor et al.   NEUROCHEMISTRY INTERNATIONAL

Pathogenesis-Targeted, Disease-Modifying Therapies in Parkinson Disease

(2013) Amaal AlDakheel et al.   Neurotherapeutics

Interaction of aldehydes derived from lipid peroxidation and membrane proteins

(2013) Stefania Pizzimenti et al.   Frontiers in Physiology

The antioxidant effect of β-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation

(2012) Miguel Angel Calleja et al.   BRITISH JOURNAL OF NUTRITION

Rotenone-induced neurotoxicity in rat brain areas: A study on neuronal and neuronal supportive cells

(2012) S. Swarnkar et al.   NEUROSCIENCE

Anti-inflammatory properties rather than anti-oxidant capability is the major mechanism of neuroprotection by sodium salicylate in a chronic rotenone model of Parkinson’s disease

(2012) P. Thakur et al.   NEUROSCIENCE

Cellular and molecular mechanisms of antioxidants in Parkinson's disease

(2012) Jhon Jairo Sutachan et al.   NUTRITIONAL NEUROSCIENCE

Effects of natural antioxidants in neurodegenerative disease

(2012) Sonia Luz Albarracin et al.   NUTRITIONAL NEUROSCIENCE

Emerging roles of microglial activation and non-motor symptoms in Parkinson's disease

(2012) Karlijn J. Doorn et al.   PROGRESS IN NEUROBIOLOGY

β-Caryophyllene Inhibits Dextran Sulfate Sodium-Induced Colitis in Mice through CB2 Receptor Activation and PPARγ Pathway

(2011) Allisson Freire Bento et al.   AMERICAN JOURNAL OF PATHOLOGY

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Anti-Parkinsonian drug discovery from herbal medicines: What have we got from neurotoxic models?

(2011) Ju-Xian Song et al.   JOURNAL OF ETHNOPHARMACOLOGY

Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinsons Disease

(2011) J. P. Little et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Phytocannabinoids as novel therapeutic agents in CNS disorders

(2011) Andrew J. Hill et al.   PHARMACOLOGY & THERAPEUTICS

A highly reproducible rotenone model of Parkinson's disease

(2009) Jason R. Cannon et al.   NEUROBIOLOGY OF DISEASE

Beta-caryophyllene is a dietary cannabinoid

(2008) Jürg Gertsch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS