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Title
The Regulation of Bone Metabolism and Disorders by Wnt Signaling
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 22, Pages 5525
Publisher
MDPI AG
Online
2019-11-07
DOI
10.3390/ijms20225525
References
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Note: Only part of the references are listed.- WNT1-associated osteogenesis imperfecta with atrophic frontal lobes and arachnoid cysts
- (2019) Piranit Nik Kantaputra et al. JOURNAL OF HUMAN GENETICS
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- (2019) Tsutomu Takeuchi et al. ANNALS OF THE RHEUMATIC DISEASES
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- (2019) Toshihisa Komori INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2019) Danieau et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2019) Mary Taub INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Anne-Laure Giraudet et al. BMC CANCER
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- (2018) Juliane Colditz et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2018) Joseph G. Crompton et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2018) V. Deshmukh et al. OSTEOARTHRITIS AND CARTILAGE
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- (2018) Steve Stegen et al. Nature Communications
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- (2018) Ping Miao et al. Oncotarget
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- (2018) Philipp Manegold et al. Cancers
- The clinical potential of romosozumab for the prevention of fractures in postmenopausal women with osteoporosis
- (2018) Anne Sophie Koldkjær Sølling et al. Therapeutic Advances in Musculoskeletal Disease
- Depleting the carboxy-terminus of human Wnt5a attenuates collagen-induced arthritis in DBA/1 mice
- (2018) Wei Cao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2018) Emmanuelle Szenker-Ravi et al. NATURE
- Clinical advantages and disadvantages of anabolic bone therapies targeting the WNT pathway
- (2018) Natasha M. Appelman-Dijkstra et al. Nature Reviews Endocrinology
- SMAD1/5 signaling in osteoclasts regulates bone formation via coupling factors
- (2018) Amy Tasca et al. PLoS One
- Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study
- (2018) Katerina Trajanoska et al. BMJ-British Medical Journal
- Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
- (2018) Hyeonwoo Kim et al. CELL
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- (2018) Masanori Koide et al. JOURNAL OF BONE AND MINERAL METABOLISM
- Clinical immunity in bone and joints
- (2018) Yoshiya Tanaka JOURNAL OF BONE AND MINERAL METABOLISM
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- (2018) Peng Sun et al. JOURNAL OF CELLULAR PHYSIOLOGY
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- (2018) Julia Luther et al. Science Translational Medicine
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- (2016) Gui-Xun Shi et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction
- (2016) Corinna Wehmeyer et al. Science Translational Medicine
- Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures
- (2016) Unnur Styrkarsdottir et al. Nature Communications
- SIKs control osteocyte responses to parathyroid hormone
- (2016) Marc N. Wein et al. Nature Communications
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- (2016) Monica Florio et al. Nature Communications
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- (2016) Ryuma Haraguchi et al. Scientific Reports
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- (2015) Megan M Weivoda et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways
- (2015) Megan M Weivoda et al. JOURNAL OF BONE AND MINERAL RESEARCH
- HDAC5 Controls MEF2C-Driven Sclerostin Expression in Osteocytes
- (2015) Marc N Wein et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2015) Chantida Pawaputanon Na Mahasarakham et al. JOURNAL OF CELLULAR PHYSIOLOGY
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- (2015) Jian Yu et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2015) Kimberly A Aldinger et al. JOURNAL OF MEDICAL GENETICS
- Wnt signaling in cartilage development and diseases: lessons from animal studies
- (2015) Yu Usami et al. LABORATORY INVESTIGATION
- Short-term and long-term effects of osteoporosis therapies
- (2015) Ian R. Reid Nature Reviews Endocrinology
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- (2015) B Madan et al. ONCOGENE
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- (2015) Phuong N. Le et al. PHARMACOLOGY & THERAPEUTICS
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- (2015) Lei Xiong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2015) Xiaolin Tu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- Loss of sclerostin promotes osteoarthritis in mice via β-catenin-dependent and -independent Wnt pathways
- (2015) Wafa Bouaziz et al. ARTHRITIS RESEARCH & THERAPY
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- (2015) Akira Sato et al. Scientific Reports
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- (2014) Heinz-Josef Lenz et al. CANCER SCIENCE
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- (2014) W. de Lau et al. GENES & DEVELOPMENT
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- (2014) Bo Yu et al. NATURE MEDICINE
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- (2014) R. Sapir-Koren et al. OSTEOPOROSIS INTERNATIONAL
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- (2008) T A C M van Geel et al. ANNALS OF THE RHEUMATIC DISEASES
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- (2008) Xiaodong Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2008) Zhong Wang et al. NATURE
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- (2008) Charles A. O'Brien et al. PLoS One
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