Osteoimmunology: The Conceptual Framework Unifying the Immune and Skeletal Systems
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Title
Osteoimmunology: The Conceptual Framework Unifying the Immune and Skeletal Systems
Authors
Keywords
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Journal
PHYSIOLOGICAL REVIEWS
Volume 97, Issue 4, Pages 1295-1349
Publisher
American Physiological Society
Online
2017-08-17
DOI
10.1152/physrev.00036.2016
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- Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
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- Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
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- Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
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- A unique case of fibrodysplasia ossificans progressiva with anACVR1 mutation, G356D, other than the common mutation (R206H)
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- Regulation of bone remodeling by the central and peripheral nervous system
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- Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts
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- Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitis
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- Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanercept
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- Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: A key mechanism in osteoporosis
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- Shared Principles in NF-κB Signaling
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- Regulatory T Cells and Immune Tolerance
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- BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
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- Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input
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- Advances in osteoclast biology resulting from the study of osteopetrotic mutations
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- Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1
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- Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
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- The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator
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- Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity
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- The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance
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- DAP10- and DAP12-associated receptors in innate immunity
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- Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength
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- NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism
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- Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
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- BMP type I receptor inhibition reduces heterotopic ossification
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- Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes
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- Osteoclasts Control Osteoblast Chemotaxis via PDGF-BB/PDGF Receptor Beta Signaling
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- TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL
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- Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis
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- Osteoblastic regulation of B lymphopoiesis is mediated by Gs -dependent signaling pathways
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- Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate
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- Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption
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- Dysregulation of Local Stem/Progenitor Cells as a Common Cellular Mechanism for Heterotopic Ossification
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- Genetics, pathogenesis and complications of osteopetrosis
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- Gaucher disease
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- NFATc1 Induces Osteoclast Fusion Via Up-Regulation of Atp6v0d2 and the Dendritic Cell-Specific Transmembrane Protein (DC-STAMP)
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