Non-canonical Wnt signals regulate cytoskeletal remodeling in osteoclasts

The Sealing Zone in Osteoclasts: A Self-Organized Structure on the Bone

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Control of Mechanotransduction by Molecular Clutch Dynamics

(2018) Alberto Elosegui-Artola et al.   TRENDS IN CELL BIOLOGY

Biogenesis of podosome rosettes through fission

(2018) Szu-Lin Kuo et al.   Scientific Reports

The Rho-specific guanine nucleotide exchange factor Plekhg5 modulates cell polarity, adhesion, migration, and podosome organization in macrophages and osteoclasts

(2017) Mayumi Iwatake et al.   EXPERIMENTAL CELL RESEARCH

Time-lapse reveals that osteoclasts can move across the bone surface while resorbing

(2017) Kent Søe et al.   JOURNAL OF CELL SCIENCE

Osteoimmunology: The Conceptual Framework Unifying the Immune and Skeletal Systems

(2017) Kazuo Okamoto et al.   PHYSIOLOGICAL REVIEWS

Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling

(2017) Shunsuke Uehara et al.   Science Signaling

Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling

(2017) Shunsuke Uehara et al.   Science Signaling

Osteoclast function and bone-resorbing activity: An overview

(2016) Niroshani Surangika Soysa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of invadopodia by mechanical signaling

(2016) Aron Parekh et al.   EXPERIMENTAL CELL RESEARCH

Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization

(2016) Marjolein B. M. Meddens et al.   Nature Communications

VEGF-A/Notch-Induced Podosomes Proteolyse Basement Membrane Collagen-IV during Retinal Sprouting Angiogenesis

(2016) Pirjo Spuul et al.   Cell Reports

Postmenopausal osteoporosis

(2016) Richard Eastell et al.   Nature Reviews Disease Primers

Specification of Architecture and Function of Actin Structures by Actin Nucleation Factors

(2015) Colleen T. Skau et al.   Annual Review of Biophysics

The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts

(2015) Gnanasagar J. Thirukonda et al.   JOURNAL OF BONE AND MINERAL METABOLISM

The effects of tumour necrosis factor-α on bone cells involved in periodontal alveolar bone loss; osteoclasts, osteoblasts and osteocytes

(2015) K. Algate et al.   JOURNAL OF PERIODONTAL RESEARCH

Tools of the trade: podosomes as multipurpose organelles of monocytic cells

(2014) Stefan Linder et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Vinculin Regulates Osteoclast Function

(2014) Tomohiro Fukunaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Podosomes of dendritic cells facilitate antigen sampling

(2014) M. V. Baranov et al.   JOURNAL OF CELL SCIENCE

Steering cell migration: lamellipodium dynamics and the regulation of directional persistence

(2014) Matthias Krause et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Spatiotemporal organization and mechanosensory function of podosomes

(2014) Koen van den Dries et al.   Cell Adhesion & Migration

Podosome organization drives osteoclast-mediated bone resorption

(2014) Dan Georgess et al.   Cell Adhesion & Migration

Physiological roles of Rho and Rho effectors in mammals

(2013) Dean Thumkeo et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

p130Cas, Crk-Associated Substrate, Plays Important Roles in Osteoclastic Bone Resorption

(2013) Yoshie Nagai et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Dynamic visualization of RANKL and Th17-mediated osteoclast function

(2013) Junichi Kikuta et al.   JOURNAL OF CLINICAL INVESTIGATION

Basic research and clinical applications of bisphosphonates in bone disease: what have we learned over the last 40 years?

(2013) Xiao-Long Xu et al.   Journal of Translational Medicine

Talin1 and Rap1 Are Critical for Osteoclast Function

(2012) W. Zou et al.   MOLECULAR AND CELLULAR BIOLOGY

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

(2012) Kazuhiro Maeda et al.   NATURE MEDICINE

Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices — A simple method for identifying polarized osteoclasts

(2011) Takahiro Nakayama et al.   BONE

Geometry sensing by dendritic cells dictates spatial organization and PGE2-induced dissolution of podosomes

(2011) Koen van den Dries et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rac deletion in osteoclasts causes severe osteopetrosis

(2011) M. Croke et al.   JOURNAL OF CELL SCIENCE

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells

(2011) Alan S. Mak   Cell Adhesion & Migration

Integrins, growth factors, and the osteoclast cytoskeleton

(2010) Wei Zou et al.   Annals of the New York Academy of Sciences

Denosumab and bisphosphonates: Different mechanisms of action and effects

(2010) Roland Baron et al.   BONE

N-WASP has the ability to compensate for the loss of WASP in macrophage podosome formation and chemotaxis

(2010) Beth M. Isaac et al.   EXPERIMENTAL CELL RESEARCH

Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements

(2010) Noriko Takegahara et al.   FASEB JOURNAL

The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts

(2010) Virginie Vives et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Nano-topography sensing by osteoclasts

(2010) D. Geblinger et al.   JOURNAL OF CELL SCIENCE

Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization

(2010) Yuji Ito et al.   JOURNAL OF CLINICAL INVESTIGATION

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis

(2009) Shih-Lei Lai et al.   CELL RESEARCH

Ror-family receptor tyrosine kinases in noncanonical Wnt signaling: Their implications in developmental morphogenesis and human diseases

(2009) Yasuhiro Minami et al.   DEVELOPMENTAL DYNAMICS

Dynamin Reduces Pyk2 Y402 Phosphorylation and Src Binding in Osteoclasts

(2009) A. Bruzzaniti et al.   MOLECULAR AND CELLULAR BIOLOGY

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

Wnt signaling and stem cell control

(2008) Roel Nusse   CELL RESEARCH

The Tyrosine Kinase Activity of c-Src Regulates Actin Dynamics and Organization of Podosomes in Osteoclasts

(2007) Olivier Destaing et al.   MOLECULAR BIOLOGY OF THE CELL