The Wnt5a-Ror2 axis promotes the signaling circuit between interleukin-12 and interferon-γ in colitis

Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively

(2015) Kensaku Shojima et al.   Scientific Reports

A Noncanonical Frizzled2 Pathway Regulates Epithelial-Mesenchymal Transition and Metastasis

(2014) Taranjit S. Gujral et al.   CELL

Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4

(2014) Chien-Hsiung Yu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Intestinal dendritic cells in the regulation of mucosal immunity

(2014) Vasileios Bekiaris et al.   IMMUNOLOGICAL REVIEWS

Wnt5a signaling increases IL-12 secretion by human dendritic cells and enhances IFN-γ production by CD4+ T cells

(2014) Jaris Valencia et al.   IMMUNOLOGY LETTERS

Wnt5a-Rac1-NF- B Homeostatic Circuitry Sustains Innate Immune Functions in Macrophages

(2014) D. Naskar et al.   JOURNAL OF IMMUNOLOGY

Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling

(2013) Yu Qiao et al.   IMMUNITY

Canonical and Noncanonical Wnt Proteins Program Dendritic Cell Responses for Tolerance

(2013) C. Oderup et al.   JOURNAL OF IMMUNOLOGY

Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche

(2012) Ryohichi Sugimura et al.   CELL

Regulation of intestinal homeostasis by innate and adaptive immunity

(2012) H. Kayama et al.   INTERNATIONAL IMMUNOLOGY

Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling

(2012) H. Sakane et al.   JOURNAL OF CELL SCIENCE

Ecto-Nucleoside Triphosphate Diphosphohydrolase 7 Controls Th17 Cell Responses through Regulation of Luminal ATP in the Small Intestine

(2012) T. Kusu et al.   JOURNAL OF IMMUNOLOGY

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

(2012) Kazuhiro Maeda et al.   NATURE MEDICINE

Intestinal CX3C chemokine receptor 1high (CX3CR1high) myeloid cells prevent T-cell-dependent colitis

(2012) H. Kayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt5a: its signalling, functions and implication in diseases

(2011) A. Kikuchi et al.   Acta Physiologica

A New Subset of CD103+CD8 + Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity

(2011) K. Fujimoto et al.   JOURNAL OF IMMUNOLOGY

Gut-associated lymphoid tissue, T cell trafficking, and chronic intestinal inflammation

(2010) Iurii Koboziev et al.   Annals of the New York Academy of Sciences

Homeostasis and Inflammation in the Intestine

(2010) Wendy S. Garrett et al.   CELL

Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10

(2010) Yoshiyasu Ueda et al.   INTERNATIONAL IMMUNOLOGY

Wnt5b–Ryk pathway provides directional signals to regulate gastrulation movement

(2010) Shengda Lin et al.   JOURNAL OF CELL BIOLOGY

Wnt5a Induces Endothelial Inflammation via  -Catenin-Independent Signaling

(2010) J. Kim et al.   JOURNAL OF IMMUNOLOGY

Activation of  -Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine

(2010) S. Manicassamy et al.   SCIENCE

Cell/tissue-tropic functions of Wnt5a signaling in normal and cancer cells

(2010) Michiru Nishita et al.   TRENDS IN CELL BIOLOGY

Wnt5a regulates distinct signalling pathways by binding to Frizzled2

(2009) Akira Sato et al.   EMBO JOURNAL

Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases

(2009) Xiaoyu Hu et al.   IMMUNITY

NFATc1 Mediates Toll-Like Receptor-Independent Innate Immune Responses during Trypanosoma cruzi Infection

(2009) Hisako Kayama et al.   PLoS Pathogens

Wnt5a is expressed in murine and human atherosclerotic lesions

(2008) Mark A. Christman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Wnt5A/CaMKII Signaling Contributes to the Inflammatory Response of Macrophages and Is a Target for the Antiinflammatory Action of Activated Protein C and Interleukin-10

(2008) Claudia Pereira et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Class-specific Regulation of Pro-inflammatory Genes by MyD88 Pathways and IκBζ

(2008) Hisako Kayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE