Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin
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Title
Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-06-26
DOI
10.1038/s41467-018-04679-7
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Note: Only part of the references are listed.- The skeletal vascular system – Breathing life into bone tissue
- (2017) Steve Stegen et al. BONE
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- (2016) Steve Stegen et al. BONE
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- (2016) Harry K Genant et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin
- (2015) Colleen Wu et al. GENES & DEVELOPMENT
- The Wnt Inhibitor Sclerostin Is Up-regulated by Mechanical Unloading in Osteocytesin Vitro
- (2015) Jordan M. Spatz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5
- (2015) Timur A Yorgan et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Temporal changes in systemic and local expression of bone turnover markers during six months of sclerostin antibody administration to ovariectomized rats
- (2014) Marina Stolina et al. BONE
- The Sirtuin1 Activator SRT3025 Down-Regulates Sclerostin and Rescues Ovariectomy-Induced Bone Loss and Biomechanical Deterioration in Female Mice
- (2014) Hanna Artsi et al. ENDOCRINOLOGY
- Direct measurement of local oxygen concentration in the bone marrow of live animals
- (2014) Joel A. Spencer et al. NATURE
- Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
- (2014) Anjali P. Kusumbe et al. NATURE
- Romosozumab in Postmenopausal Women with Low Bone Mineral Density
- (2014) Michael R. McClung et al. NEW ENGLAND JOURNAL OF MEDICINE
- Dimethyloxalylglycine Prevents Bone Loss in Ovariectomized C57BL/6J Mice through Enhanced Angiogenesis and Osteogenesis
- (2014) Jia Peng et al. PLoS One
- Up-regulation of glycolytic metabolism is required for HIF1 -driven bone formation
- (2014) J. N. Regan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expansion of Murine Periosteal Progenitor Cells with Fibroblast Growth Factor 2 Reveals an Intrinsic Endochondral Ossification Program Mediated by Bone Morphogenetic Protein 2
- (2014) Nick van Gastel et al. STEM CELLS
- Prolyl Hydroxylase Inhibitors Protect from the Bone Loss in Ovariectomy Rats by Increasing Bone Vascularity
- (2013) Xiaodong Liu et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin
- (2013) Petra Simic et al. EMBO Molecular Medicine
- The Osteocyte: An Endocrine Cell … and More
- (2013) Sarah L. Dallas et al. ENDOCRINE REVIEWS
- WNT signaling in bone homeostasis and disease: from human mutations to treatments
- (2013) Roland Baron et al. NATURE MEDICINE
- Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches
- (2013) Ernesto Canalis Nature Reviews Endocrinology
- The role of estrogen and androgen receptors in bone health and disease
- (2013) Stavros C. Manolagas et al. Nature Reviews Endocrinology
- The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO
- (2012) Erinn B. Rankin et al. CELL
- The updated biology of hypoxia-inducible factor
- (2012) Samantha N Greer et al. EMBO JOURNAL
- Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee
- (2012) David W Dempster et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D–induced inhibition of bone mineralization
- (2012) Liesbet Lieben et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypoxia-driven pathways in bone development, regeneration and disease
- (2012) Christa Maes et al. Nature Reviews Rheumatology
- Targeted deletion of Sost distal enhancer increases bone formation and bone mass
- (2012) N. M. Collette et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engineering Vascularized Bone: Osteogenic and Proangiogenic Potential of Murine Periosteal Cells
- (2012) Nick van Gastel et al. STEM CELLS
- Development of micro-CT protocols for in vivo follow-up of mouse bone architecture without major radiation side effects
- (2011) K. Laperre et al. BONE
- Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading
- (2011) Xiaolin Tu et al. BONE
- Sirt1 Is a Regulator of Bone Mass and a Repressor ofSostEncoding for Sclerostin, a Bone Formation Inhibitor
- (2011) Einav Cohen-Kfir et al. ENDOCRINOLOGY
- Hypoxia Increases Sirtuin 1 Expression in a Hypoxia-inducible Factor-dependent Manner
- (2011) Rui Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo
- (2011) Stacey M Woo et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Matrix-embedded cells control osteoclast formation
- (2011) Jinhu Xiong et al. NATURE MEDICINE
- Evidence for osteocyte regulation of bone homeostasis through RANKL expression
- (2011) Tomoki Nakashima et al. NATURE MEDICINE
- Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway
- (2011) Asiri R. Wijenayaka et al. PLoS One
- Role of HIF-1α in skeletal development
- (2010) Chao Wan et al. Annals of the New York Academy of Sciences
- Guidelines for assessment of bone microstructure in rodents using micro-computed tomography
- (2010) Mary L Bouxsein et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The amazing osteocyte
- (2010) Lynda F Bonewald JOURNAL OF BONE AND MINERAL RESEARCH
- Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
- (2009) Massimiliano Mazzone et al. CELL
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- (2009) Chuwen Lin et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts
- (2009) Nobuhiro Kamiya et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Hypoxia-inducible factors 1α and 2α exert both distinct and overlapping functions in long bone development
- (2009) Stacy H. Shomento et al. JOURNAL OF CELLULAR BIOCHEMISTRY
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- (2008) Johanna Myllyharju ANNALS OF MEDICINE
- TRPV4-Mediated Calcium Influx Regulates Terminal Differentiation of Osteoclasts
- (2008) Ritsuko Masuyama et al. Cell Metabolism
- Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength
- (2008) Xiaodong Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
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