BMP-2 Enhances Lgr4 Gene Expression in Osteoblastic Cells

Mechanotransduction pathways in bone pathobiology

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Inferences from genetically modified mouse models on the skeletal actions of vitamin D

(2015) D Goltzman   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

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(2015) Ian R. Reid   Nature Reviews Endocrinology

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The role of vitamin D in human fracture healing: a systematic review of the literature

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Literature review: The effects of teriparatide therapy at the hip in patients with osteoporosis

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Challenges for the Development of Bone-Forming Agents in Europe

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Biological agents in management of osteoporosis

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Targeting the LRP5 Pathway Improves Bone Properties in a Mouse Model of Osteogenesis Imperfecta

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Bone marrow mesenchymal stem cells and TGF-β signaling in bone remodeling

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A Systematic Review of Cost-Effectiveness Analyses of Drugs for Postmenopausal Osteoporosis

(2014) Mickaël Hiligsmann et al.   PHARMACOECONOMICS

Osteoporosis

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Glucocorticoids and bone: local effects and systemic implications

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Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis

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Vitamin D and gene networks in human osteoblasts

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Anabolic and Antiresorptive Therapy for Osteoporosis: Combination and Sequential Approaches

(2014) Felicia Cosman   Current Osteoporosis Reports

Glucocorticoids and osteocyte autophagy

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Glucocorticoid-induced osteoporosis: An update on effects and management

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Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

(2013) Unnur Styrkarsdottir et al.   NATURE

Wnt Signaling and the Control of Human Stem Cell Fate

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Fibroblast growth factor signaling controlling bone formation: An update

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Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation

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Nemo-like kinase inhibits osteoblastogenesis by suppressing bone morphogenetic protein and WNT canonical signaling

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GPR48 Increases Mineralocorticoid Receptor Gene Expression

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Conditional Knockout of Lgr4 Leads to Impaired Ductal Elongation and Branching Morphogenesis in Mouse Mammary Glands

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Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways

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Update in New Anabolic Therapies for Osteoporosis

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Regulation of bone formation and remodeling by G-protein-coupled receptor 48

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Defective development of the gall bladder and cystic duct in Lgr4- hypomorphic mice

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Wnt11 Promotes Osteoblast Maturation and Mineralization through R-spondin 2

(2009) Michael S. Friedman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Growth factor control of bone mass

(2009) Ernesto Canalis   JOURNAL OF CELLULAR BIOCHEMISTRY

BMP-2 modulates β-catenin signaling through stimulation ofLrp5expression and inhibition of β-TrCP expression in osteoblasts

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R-spondin1 synergizes with Wnt3A in inducing osteoblast differentiation and osteoprotegerin expression

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Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2

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