Lrp5 functions in bone to regulate bone mass

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis

(2010) Vijay K Yadav et al.   NATURE MEDICINE

Serotonin Rising — The Bone, Brain, Bowel Connection

(2009) Clifford J. Rosen   NEW ENGLAND JOURNAL OF MEDICINE

Growth retardation and altered autonomic control in mice lacking brain serotonin

(2009) N. Alenina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

The Binding Between Sclerostin and LRP5 is Altered by DKK1 and by High-Bone Mass LRP5 Mutations

(2008) Wendy Balemans et al.   CALCIFIED TISSUE INTERNATIONAL

When the Gut Talks to Bone

(2008) Fanxin Long   CELL

Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

(2008) Vijay K. Yadav et al.   CELL

Neurogenesis and asymmetric cell division

(2008) Weimin Zhong et al.   CURRENT OPINION IN NEUROBIOLOGY

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Discovery and Characterization of Novel Tryptophan Hydroxylase Inhibitors That Selectively Inhibit Serotonin Synthesis in the Gastrointestinal Tract

(2008) Q. Liu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Genetic Disruption of Both Tryptophan Hydroxylase Genes Dramatically Reduces Serotonin and Affects Behavior in Models Sensitive to Antidepressants

(2008) Katerina V. Savelieva et al.   PLoS One

The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains

(2007) Katja Tenner et al.   NEUROSCIENCE LETTERS