The impact of microbiota-derived short-chain fatty acids on macrophage activities in disease: Mechanisms and therapeutic potentials
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Title
The impact of microbiota-derived short-chain fatty acids on macrophage activities in disease: Mechanisms and therapeutic potentials
Authors
Keywords
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Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 165, Issue -, Pages 115276
Publisher
Elsevier BV
Online
2023-08-04
DOI
10.1016/j.biopha.2023.115276
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- The Inflammatory Chemokine CCL5 and Cancer Progression
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- Review article: the role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases
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- Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation
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- The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
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- Reduction of CD68+ Macrophages and Decreased IL-17 Expression in Intestinal Mucosa of Patients with Inflammatory Bowel Disease Strongly Correlate With Endoscopic Response and Mucosal Healing following Infliximab Therapy
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- Critical Role of Histone Acetylation by p300 in Human Placental 11β-HSD2 Expression
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- Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
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- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
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- Inflammatory chemokines and metastasis—tracing the accessory
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- Induction of Porcine Host Defense Peptide Gene Expression by Short-Chain Fatty Acids and Their Analogs
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- The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis
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- Butyrate increases IL-23 production by stimulated dendritic cells
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- Short-Chain Fatty Acids Suppress Lipopolysaccharide-Induced Production of Nitric Oxide and Proinflammatory Cytokines Through Inhibition of NF-κB Pathway in RAW264.7 Cells
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- Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
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- Short-Chain Fatty Acids Induce Pro-Inflammatory Cytokine Production Alone and in Combination with Toll-Like Receptor Ligands
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- Downregulation of breast cancer resistance protein in colon adenomas reduces cellular xenobiotic resistance and leads to accumulation of a food-derived carcinogen
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- Transcriptional Regulation of ATP-binding Cassette Transporter A1 Expression by a Novel Signaling Pathway
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- Oral administration of sodium butyrate attenuates inflammation and mucosal lesion in experimental acute ulcerative colitis
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- Hemoglobin Directs Macrophage Differentiation and Prevents Foam Cell Formation in Human Atherosclerotic Plaques
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- Butyrate Enhances Disease Resistance of Chickens by Inducing Antimicrobial Host Defense Peptide Gene Expression
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- Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)
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- Macrophage Diversity Enhances Tumor Progression and Metastasis
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- Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils
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- The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
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- Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes
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- Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3
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- Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways
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- Gene expression analysis of a human enterocyte cell line reveals downregulation of cholesterol biosynthesis in response to short-chain fatty acids
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- Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon
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- Butyrate and trichostatin A attenuate nuclear factor κB activation and tumor necrosis factor α secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells
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