Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Hypoxia attenuates inflammatory mediators production induced by Acanthamoeba via Toll-like receptor 4 signaling in human corneal epithelial cells

(2012) Hong Pan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Elevated plasma succinate in PTEN, SDHB and SDHD mutation–positive individuals

(2012) Judith A. Hobert et al.   GENETICS IN MEDICINE

The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation

(2012) Sarah L. Doyle et al.   Nature Communications

Non-vision adverse events with vigabatrin therapy

(2011) S. D. Walker et al.   ACTA NEUROLOGICA SCANDINAVICA

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

(2011) Sarah R. Walmsley et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

Hypoxia and succinate antagonize 2-deoxyglucose effects on glioblastoma

(2010) Francesca Pistollato et al.   BIOCHEMICAL PHARMACOLOGY

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

(2010) Seth L Masters et al.   NATURE IMMUNOLOGY

Triggering the succinate receptor GPR91 on dendritic cells enhances immunity

(2008) Tina Rubic et al.   NATURE IMMUNOLOGY