FFAR3 modulates insulin secretion and global gene expression in mouse islets

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes

(2015) Cong Tang et al.   NATURE MEDICINE

The G Protein-coupled Receptor P2Y14Influences Insulin Release and Smooth Muscle Function in Mice

(2014) Jaroslawna Meister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Fractalkine/CX3CR1 System Regulates β Cell Function and Insulin Secretion

(2013) Yun Sok Lee et al.   CELL

Metabolic Signaling in Fuel-Induced Insulin Secretion

(2013) Marc Prentki et al.   Cell Metabolism

 -Hydroxybutyrate Modulates N-Type Calcium Channels in Rat Sympathetic Neurons by Acting as an Agonist for the G-Protein-Coupled Receptor FFA3

(2013) Y.-J. Won et al.   JOURNAL OF NEUROSCIENCE

Congenital Hyperinsulinism Caused by Hexokinase I Expression or Glucokinase-Activating Mutation in a Subset of  -Cells

(2012) J.-C. Henquin et al.   DIABETES

Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3

(2012) Brian D. Hudson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Short chain fatty acids and their receptors: new metabolic targets

(2012) Brian T. Layden et al.   Translational Research

Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes

(2011) Joseph P. Tiano et al.   JOURNAL OF CLINICAL INVESTIGATION

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

(2011) I. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid receptors and islet function: therapeutic implications?

(2009) M. A. Kebede et al.   DIABETES OBESITY & METABOLISM

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Studies with leucine, β-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion

(2008) M MACDONALD et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetoacetate and β-hydroxybutyrate in combination with other metabolites release insulin from INS-1 cells and provide clues about pathways in insulin secretion

(2007) Michael J. MacDonald et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY