Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Characterization of Phosphoglycerate Kinase-1 Expression of Stromal Cells Derived from Tumor Microenvironment in Prostate Cancer Progression

(2010) J. Wang et al.   CANCER RESEARCH

Ovarian cancer-derived lysophosphatidic acid stimulates secretion of VEGF and stromal cell-derived factor-1α from human mesenchymal stem cells

(2010) Eun Su Jeon et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Chemokines and chemokine receptors: new insights into cancer-related inflammation

(2010) Gwendal Lazennec et al.   TRENDS IN MOLECULAR MEDICINE

Site-specific metastasis formation

(2010) Adit Ben-Baruch   Cell Adhesion & Migration

Caveolin-1−/− Null Mammary Stromal Fibroblasts Share Characteristics with Human Breast Cancer-Associated Fibroblasts

(2009) Federica Sotgia et al.   AMERICAN JOURNAL OF PATHOLOGY

SDF-1α G801A Polymorphism Predicts Lymph Node Metastasis in Stage T3 Colorectal Cancer

(2009) Shih-Ching Chang et al.   ANNALS OF SURGICAL ONCOLOGY

Mesenchymal Stem Cells: Flip Side of the Coin

(2009) Pravin J. Mishra et al.   CANCER RESEARCH

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

(2009) F. Colotta et al.   CARCINOGENESIS

Cancer-associated fibroblasts and tumor growth – bystanders turning into key players

(2009) Arne Östman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Chemokine Receptors as Targets for Cancer Therapy

(2009) Xuesong Wu et al.   CURRENT PHARMACEUTICAL DESIGN

Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation

(2009) Alberto Mantovani et al.   HUMAN IMMUNOLOGY

The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expressionin vitroand the stromal microenvironmentin vivo

(2009) Ling Li et al.   INTERNATIONAL JOURNAL OF CANCER

Transforming Growth Factor-β Promotes Recruitment of Bone Marrow Cells and Bone Marrow-derived Mesenchymal Stem Cells through Stimulation of MCP-1 Production in Vascular Smooth Muscle Cells

(2009) Fan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

CXCR4 and Matrix Metalloproteinase-1 Are Elevated in Breast Carcinoma-Associated Fibroblasts and in Normal Mammary Fibroblasts Exposed to Factors Secreted by Breast Cancer Cells

(2009) S. M. Eck et al.   MOLECULAR CANCER RESEARCH

Differential Influence of Normal and Cancer-Associated Fibroblasts on the Growth of Human Epithelial Cells in an In vitro Cocultivation Model of Prostate Cancer

(2009) N. Paland et al.   MOLECULAR CANCER RESEARCH

Clustering of fibroblasts induces proinflammatory chemokine secretion promoting leukocyte migration

(2009) Anna Enzerink et al.   MOLECULAR IMMUNOLOGY

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

(2009) Erika L. Spaeth et al.   PLoS One

CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth

(2009) M. Augsten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-promoting phenotype of CD90hiprostate cancer-associated fibroblasts

(2009) Hongjuan Zhao et al.   PROSTATE

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression

(2009) Masayuki Shimoda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy?

(2009) Tamas A. Gonda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Direct Evidence of Mesenchymal Stem Cell Tropism for Tumor and Wounding Microenvironments Using In Vivo Bioluminescent Imaging

(2009) Shannon Kidd et al.   STEM CELLS

Activation of Signal Transducers and Activators of Transcription 3 and Focal Adhesion Kinase by Stromal Cell-Derived Factor 1 Is Required for Migration of Human Mesenchymal Stem Cells in Response to Tumor Cell-Conditioned Medium

(2009) Hui Gao et al.   STEM CELLS

Chemokines as Mediators of Neovascularization

(2008) Ellen C. Keeley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cancer related inflammation: The macrophage connection

(2008) Antonio Sica et al.   CANCER LETTERS

The inflammatory chemokines CCL2 and CCL5 in breast cancer

(2008) Gali Soria et al.   CANCER LETTERS

Yin-Yang Activities and Vicious Cycles in the Tumor Microenvironment

(2008) I. P. Witz   CANCER RESEARCH

A Novel Bone Morphogenetic Protein Signaling in Heterotypic Cell Interactions in Prostate Cancer

(2008) S. Yang et al.   CANCER RESEARCH

Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells

(2008) P. J. Mishra et al.   CANCER RESEARCH

The Interleukin-8 Pathway in Cancer

(2008) D. J.J. Waugh et al.   CLINICAL CANCER RESEARCH

The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages

(2008) Paola Allavena et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Role of bone marrow-derived cells in experimental chronic pancreatitis

(2008) F Marrache et al.   GUT

CXCL8/IL-8 and CXCL12/SDF-1α co-operatively promote invasiveness and angiogenesis in pancreatic cancer

(2008) Yoichi Matsuo et al.   INTERNATIONAL JOURNAL OF CANCER

Stromal Fibroblasts Activated by Tumor Cells Promote Angiogenesis in Mouse Gastric Cancer

(2008) Xiaoying Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Concise Review: Mesenchymal Stromal Cells: Potential for Cardiovascular Repair

(2008) Peter J. Psaltis et al.   STEM CELLS

Expression of CCR5 receptors on Reed–Sternberg cells and Hodgkin lymphoma cell lines: Involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions

(2007) Donatella Aldinucci et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of HGF and SDF-1 expression by oral fibroblasts – Implications for invasion of oral cancer

(2007) Aisling J. Daly et al.   ORAL ONCOLOGY