Bacteroides fragilis restricts colitis-associated cancer via negative regulation of the NLRP3 axis

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway

(2021) Yanglin Wu et al.   JOURNAL OF NANOBIOTECHNOLOGY

Colorectal cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Gut microbiota regulate tumor metastasis via circRNA/miRNA networks

(2020) Zhuxian Zhu et al.   Gut Microbes

Arctigenin disrupts NLRP3 inflammasome assembly in colonic macrophages via downregulating fatty acid oxidation to prevent colitis-associated cancer

(2020) Simiao Qiao et al.   CANCER LETTERS

Gut Dysbiosis Contributes to the Imbalance of Treg and Th17 Cells in Graves’ Disease Patients by Propionic Acid

(2020) Xinhuan Su et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Roles of the Polyphenol–Gut Microbiota Interaction in Alleviating Colitis and Preventing Colitis-Associated Colorectal Cancer

(2020) Yiying Zhao et al.   Advances in Nutrition

Role of myeloid-derived suppressor cells in the promotion and immunotherapy of colitis-associated cancer

(2020) Yungang Wang et al.   Journal for ImmunoTherapy of Cancer

Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation

(2019) Vishal Singh et al.   GUT

The Crohn’s Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy

(2019) Subhash Mehto et al.   MOLECULAR CELL

Microbiota and metabolites in metabolic diseases

(2019) Patrice D. Cani   Nature Reviews Endocrinology

Fatty acid 2-hydroxylation inhibits tumor growth and increases sensitivity to cisplatin in gastric cancer

(2019) Yizhou Yao et al.   EBioMedicine

Interleukin-18 in Health and Disease

(2019) Koubun Yasuda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiome and cancer immunotherapy

(2019) Weina Li et al.   CANCER LETTERS

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis

(2019) Xin Zhou et al.   Cell Reports

Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

(2019) José Luís Fachi et al.   Cell Reports

Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response

(2019) Krist Helen Antunes et al.   Nature Communications

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

(2019) Marco Orecchioni et al.   Frontiers in Immunology

Low-dose tetracycline exposure alters gut bacterial metabolism and host-immune response: “Personalized” effect?

(2019) Tharushi P. Keerthisinghe et al.   ENVIRONMENT INTERNATIONAL

Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice

(2019) Parag Kundu et al.   Science Translational Medicine

Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn’s disease

(2018) Liming Mao et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the NLRP3 inflammasome in inflammatory diseases

(2018) Matthew S. J. Mangan et al.   NATURE REVIEWS DRUG DISCOVERY

Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11

(2018) Brice Lagrange et al.   Nature Communications

Differential effects of short chain fatty acids on endothelial Nlrp3 inflammasome activation and neointima formation: Antioxidant action of butyrate

(2018) Xinxu Yuan et al.   Redox Biology

Fecal Microbiota Transplantation in Experimental Ulcerative Colitis Reveals Associated Gut Microbial and Host Metabolic Reprogramming

(2018) Zhi-Xiang Yan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

(2018) Hazel Tye et al.   Nature Communications

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course

(2018) Melanie Schirmer et al.   Cell Host & Microbe

Colitis-induced colorectal cancer and intestinal epithelial estrogen receptor beta impact gut microbiota diversity

(2018) Ahmed Ibrahim et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases

(2018) Congfei Xu et al.   Nature Communications

Faecalibacterium prausnitzii: from microbiology to diagnostics and prognostics

(2017) Mireia Lopez-Siles et al.   ISME Journal

Microbiome and colorectal cancer: Unraveling host-microbiota interactions in colitis-associated colorectal cancer development

(2017) Mingsong Kang et al.   SEMINARS IN IMMUNOLOGY

Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis

(2017) Xiaomin Yao et al.   Nature Communications

Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation

(2017) Jesus Cosin-Roger et al.   Nature Communications

Gut microbiota dysbiosis contributes to the development of hypertension

(2017) Jing Li et al.   Microbiome

Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides

(2017) Ana S. Luis et al.   Nature Microbiology

Interleukin 18 (IL-18) as a target for immune intervention

(2016) Sebastian Wawrocki et al.   ACTA BIOCHIMICA POLONICA

Screening for enterotoxigenic Bacteroides fragilis in stool samples

(2016) Jacqueline I. Keenan et al.   ANAEROBE

Gut Microbiota, Inflammation, and Colorectal Cancer

(2016) Caitlin A. Brennan et al.   Annual Review of Microbiology

Bacteroides fragilis metabolises exopolysaccharides produced by bifidobacteria

(2016) David Rios-Covian et al.   BMC MICROBIOLOGY

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

(2016) Gerard E. Kaiko et al.   CELL

Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome

(2016) Pedro A Ruiz et al.   GUT

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

(2016) H. Chu et al.   SCIENCE

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease

(2015) Yun-Hee Youm et al.   NATURE MEDICINE

Bacteroides fragilis subverts mucosal biology: from symbiont to colon carcinogenesis

(2014) Cynthia L. Sears et al.   JOURNAL OF CLINICAL INVESTIGATION

Context-dependent role of IL-18 in cancer biology and counter-regulation by IL-18BP

(2014) Marina Fabbi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A neuromorphic network for generic multivariate data classification

(2014) Michael Schmuker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ulcerative colitis-associated colorectal cancer

(2014) Masakazu Yashiro   WORLD JOURNAL OF GASTROENTEROLOGY

NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling

(2012) Irving C. Allen et al.   IMMUNITY

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enterotoxigenic Bacteroides fragilis: a Rogue among Symbiotes

(2009) C. L. Sears   CLINICAL MICROBIOLOGY REVIEWS