Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

(2014) David O’Sullivan et al.   IMMUNITY

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

(2014) Dorothy K Sojka et al.   eLife

Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes

(2013) Robert Stöhr et al.   BIOCHEMICAL JOURNAL

Reprogramming of lysosomal gene expression by interleukin-4 and Stat6

(2013) Louise M Brignull et al.   BMC GENOMICS

Low density receptor-related protein 1 (LRP1) promotes anti-inflammatory phenotype in murine macrophages

(2013) Petra May et al.   CELL AND TISSUE RESEARCH

Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

(2013) Xiaoyuan Xu et al.   Cell Metabolism

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

(2013) Stephen J. Jenkins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-4 regulates lipid metabolism by inhibiting adipogenesis and promoting lipolysis

(2013) Chang-Hui Tsao et al.   JOURNAL OF LIPID RESEARCH

Oxidized LDL Induces Alternative Macrophage Phenotype through Activation of CD36 and PAFR

(2013) Francisco J. Rios et al.   MEDIATORS OF INFLAMMATION

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

Single Nucleotide Polymorphisms within LIPA (Lysosomal Acid Lipase A) Gene Are Associated with Susceptibility to Premature Coronary Artery Disease. A Replication in the Genetic of Atherosclerotic Disease (GEA) Mexican Study

(2013) Gilberto Vargas-Alarcón et al.   PLoS One

The biology of nematode- and IL4R -dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics

(2012) G. D. Thomas et al.   BLOOD

FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling

(2012) Rudolf Zechner et al.   Cell Metabolism

Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

(2012) Larissa Cardilo-Reis et al.   EMBO Molecular Medicine

Endoplasmic Reticulum Stress Controls M2 Macrophage Differentiation and Foam Cell Formation

(2012) Jisu Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myocardial triacylglycerol metabolism

(2012) Petra C. Kienesberger et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus

(2012) Lisa A. Reynolds et al.   Seminars in Immunopathology

Atherosclerotic lesion progression is attenuated by reconstitution with bone marrow from macrophage-specific cholesteryl ester hydrolase transgenic mice

(2011) Jinghua Bie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Alternative Macrophage Activation and Metabolism

(2011) Justin I. Odegaard et al.   Annual Review of Pathology-Mechanisms of Disease

Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease

(2011) Philipp S. Wild et al.   Circulation-Cardiovascular Genetics

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

(2011) Gerritje J.W. van der Windt et al.   IMMUNITY

Cytokines, macrophage lipid metabolism and foam cells: Implications for cardiovascular disease therapy

(2011) James E. McLaren et al.   PROGRESS IN LIPID RESEARCH

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Metabolism in T cell activation and differentiation

(2010) Erika L Pearce   CURRENT OPINION IN IMMUNOLOGY

Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile

(2010) Latisha Love-Gregory et al.   HUMAN MOLECULAR GENETICS

Chylomicron- and VLDL-derived Lipids Enter the Heart through Different Pathways

(2010) Kalyani G. Bharadwaj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Ablation of Neutral Cholesterol Ester Hydrolase 1 Accelerates Atherosclerosis

(2009) Motohiro Sekiya et al.   Cell Metabolism

Mantle skewness and ridge segmentation

(2009) Satish C. Singh et al.   NATURE

Cellular fatty acid uptake: a pathway under construction

(2009) Xiong Su et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Long-term metabolic, endocrine and neuropsychological outcome of hematopoietic cell transplantation for Wolman disease

(2008) J Tolar et al.   BONE MARROW TRANSPLANTATION