Cuproptosis and cuproptosis-related genes: Emerging potential therapeutic targets in breast cancer
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Title
Cuproptosis and cuproptosis-related genes: Emerging potential therapeutic targets in breast cancer
Authors
Keywords
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Journal
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Volume 1878, Issue 6, Pages 189013
Publisher
Elsevier BV
Online
2023-10-31
DOI
10.1016/j.bbcan.2023.189013
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Note: Only part of the references are listed.- Targeting Breast Cancer Stem Cells
- (2023) Lu Zhang et al. International Journal of Biological Sciences
- Copper Death Inducer, FDX1, as a Prognostic Biomarker Reshaping Tumor Immunity in Clear Cell Renal Cell Carcinoma
- (2023) Aimin Jiang et al. Cells
- Copper-Plumbagin Complex Produces Potent Anticancer Effects by Depolymerizing Microtubules and Inducing Reactive Oxygen Species and DNA Damage
- (2023) Sandipan Mukherjee et al. ACS Omega
- Cuproptosis Induced by ROS Responsive Nanoparticles with Elesclomol and Copper Combined with αPD‐L1 for Enhanced Cancer Immunotherapy (Adv. Mater. 22/2023)
- (2023) Boda Guo et al. ADVANCED MATERIALS
- Systematic pan-cancer analysis identifies cuproptosis-related gene DLAT as an immunological and prognostic biomarker
- (2023) Lidong Xu et al. Aging-US
- Clinical significance and integrative analysis of the cuproptosis-associated genes in head and neck squamous cell carcinoma
- (2023) Qiu Peng et al. Aging-US
- Disulfiram enhances cisplatin cytotoxicity by forming a novel platinum chelate Pt(DDTC)3+
- (2023) Xue-xia Yuan et al. BIOCHEMICAL PHARMACOLOGY
- The therapeutic and prognostic role of cuproptosis-related genes in triple negative breast cancer
- (2023) Bingye Shi et al. BMC BIOINFORMATICS
- Comprehensive analysis identifies cuproptosis-related gene DLAT as a potential prognostic and immunological biomarker in pancreatic adenocarcinoma
- (2023) Xiaoling Zhang et al. BMC CANCER
- AMPK phosphorylates and stabilises copper transporter 1 to synergise metformin and copper chelator for breast cancer therapy
- (2023) Xiaomei Zhang et al. BRITISH JOURNAL OF CANCER
- Finding New Molecular Targets of Two Copper(II)-Hydrazone Complexes on Triple-Negative Breast Cancer Cells Using Mass-Spectrometry-Based Quantitative Proteomics
- (2023) Lucia M. Balsa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Overcoming drug resistance with a docetaxel and disulfiram loaded pH-sensitive nanoparticle
- (2023) K. Laxmi Swetha et al. JOURNAL OF CONTROLLED RELEASE
- Ferroptosis inducers enhanced cuproptosis induced by copper ionophores in primary liver cancer
- (2023) Weikai Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Cuproptosis engages in c-Myc-mediated breast cancer stemness
- (2023) Runtian Wang et al. Journal of Translational Medicine
- Copper‐Coordinated Covalent Organic Framework Produced a Robust Fenton‐Like Effect Inducing Immunogenic Cell Death of Tumors
- (2023) Tong Li et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Cuproptosis and its application in different cancers: an overview
- (2023) Lingyun Xu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Payload Release Profile and Anti-Cancer Stem Cell Properties of Compositionally Different Polymeric Nanoparticles Containing a Copper(II) Complex
- (2023) Ginevra Passeri et al. MOLECULES
- Expression of Ferredoxin1 in cisplatin‑resistant ovarian cancer cells confers their resistance against ferroptosis induced by cisplatin
- (2023) Ryosuke Takahashi et al. ONCOLOGY REPORTS
- Expression analysis of cell cycle related lncRNAs in breast cancer tissues
- (2023) Bashdar Mahmud Hussen et al. PATHOLOGY RESEARCH AND PRACTICE
- FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery
- (2023) Mohammad Zulkifli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrated machine learning and bioinformatic analyses used to construct a copper-induced cell death-related classifier for prognosis and immunotherapeutic response of hepatocellular carcinoma patients
- (2023) Shuai Zhao et al. Frontiers in Pharmacology
- A ceRNA network-mediated over-expression of cuproptosis-related gene SLC31A1 correlates with poor prognosis and positive immune infiltration in breast cancer
- (2023) Weibin Lian et al. Frontiers in Medicine
- DLAT as a Cuproptosis Promoter and a Molecular Target of Elesclomol in Hepatocellular Carcinoma
- (2023) Fan Gao et al. Current Medical Science
- Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients With Recurrent Glioblastoma
- (2023) Katja Werlenius et al. JAMA Network Open
- A tumor microenvironment-responsive core-shell tecto dendrimer nanoplatform for magnetic resonance imaging-guided and cuproptosis-promoted chemo-chemodynamic therapy
- (2023) Cheng Ni et al. Acta Biomaterialia
- Functional impact of non-coding RNAs in high-grade breast carcinoma: Moving from resistance to clinical applications: A comprehensive review
- (2023) Apurva Jaiswal et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Copper in cancer: From pathogenesis to therapy
- (2023) Defeng Guan et al. BIOMEDICINE & PHARMACOTHERAPY
- Cancer Cachexia and breast cancer stem cell signalling – A crosstalk of signalling molecules
- (2023) Priyanka Shivnani et al. CELLULAR SIGNALLING
- Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer
- (2023) Hongzhuang Wen et al. FASEB JOURNAL
- Betulinic acid in the treatment of breast cancer: Application and mechanism progress
- (2023) Huijuan Mu et al. Fitoterapia
- Cuproptosis-related gene SLC31A1 expression correlates with the prognosis and tumor immune microenvironment in glioma
- (2023) Jun Wang et al. FUNCTIONAL & INTEGRATIVE GENOMICS
- FDX1 regulates cellular protein lipoylation through direct binding to LIAS
- (2023) Margaret B. Dreishpoon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A risk prognostic model for patients with esophageal squamous cell carcinoma basing on cuproptosis and ferroptosis
- (2023) Jianan Li et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- The therapeutic potential of targeting regulated non-apoptotic cell death
- (2023) Kamyar Hadian et al. NATURE REVIEWS DRUG DISCOVERY
- Copper homeostasis and cuproptosis in cardiovascular disease therapeutics
- (2023) Lifang Yang et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Cuproptosis-related lncRNAs potentially predict prognosis and therapy sensitivity of breast cancer
- (2023) Xiwen Wu et al. Frontiers in Pharmacology
- Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis
- (2022) Archita Das et al. NATURE CELL BIOLOGY
- Event-free Survival with Pembrolizumab in Early Triple-Negative Breast Cancer
- (2022) Peter Schmid et al. NEW ENGLAND JOURNAL OF MEDICINE
- Copper enhances genotoxic drug resistance via ATOX1 activated DNA damage repair
- (2022) Jing Jin et al. CANCER LETTERS
- Compartmentalized metabolism supports midgestation mammalian development
- (2022) Ashley Solmonson et al. NATURE
- Deubiquitinase-targeting chimeras for targeted protein stabilization
- (2022) Nathaniel J. Henning et al. Nature Chemical Biology
- Prospective clinical trial of disulfiram plus copper in men with metastatic castration‐resistant prostate cancer
- (2022) Tian Zhang et al. PROSTATE
- Copper-induced cell death
- (2022) Martha A. Kahlson et al. SCIENCE
- Copper induces cell death by targeting lipoylated TCA cycle proteins
- (2022) Peter Tsvetkov et al. SCIENCE
- Newly identified disorder of copper metabolism caused by variants in CTR1, a high-affinity copper transporter
- (2022) Spyros Batzios et al. HUMAN MOLECULAR GENETICS
- PM2.5 promotes NSCLC carcinogenesis through translationally and transcriptionally activating DLAT-mediated glycolysis reprograming
- (2022) Qianqian Chen et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Comprehensive Analysis of Cuproptosis-Related Genes in Immune Infiltration and Prognosis in Melanoma
- (2022) Haozhen Lv et al. Frontiers in Pharmacology
- Comprehensive analyses of PDHA1 that serves as a predictive biomarker for immunotherapy response in cancer
- (2022) Langmei Deng et al. Frontiers in Pharmacology
- CDKN2A-mediated molecular subtypes characterize the hallmarks of tumor microenvironment and guide precision medicine in triple-negative breast cancer
- (2022) Tianyi Cheng et al. Frontiers in Immunology
- Comprehensive analysis of the potential cuproptosis-related biomarker LIAS that regulates prognosis and immunotherapy of pan-cancers
- (2022) Yuan Cai et al. Frontiers in Oncology
- High expression of cuproptosis-related SLC31A1 gene in relation to unfavorable outcome and deregulated immune cell infiltration in breast cancer: an analysis based on public databases
- (2022) Linrong Li et al. BMC BIOINFORMATICS
- Database Mining Detected a Cuproptosis-Related Prognostic Signature and a Related Regulatory Axis in Breast Cancer
- (2022) Baohong Jiang et al. DISEASE MARKERS
- Disulfiram/Copper Suppresses Cancer Stem Cell Activity in Differentiated Thyroid Cancer Cells by Inhibiting BMI1 Expression
- (2022) Yung-Lun Ni et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- High expression of cuproptosis-related gene FDX1 in relation to good prognosis and immune cells infiltration in colon adenocarcinoma (COAD)
- (2022) Lizong Wang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Elesclomol: a copper ionophore targeting mitochondrial metabolism for cancer therapy
- (2022) Peijie Zheng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- System analysis based on the cuproptosis-related genes identifies LIPT1 as a novel therapy target for liver hepatocellular carcinoma
- (2022) Cheng Yan et al. Journal of Translational Medicine
- Immune Checkpoint Inhibitors and Novel Immunotherapy Approaches for Breast Cancer
- (2022) Mónica Cejuela et al. Current Oncology Reports
- Prognostic and immunological role of cuproptosis-related protein FDX1 in pan-cancer
- (2022) Chen Xiao et al. Frontiers in Genetics
- A pan-cancer analysis of copper homeostasis-related gene lipoyltransferase 1: Its potential biological functions and prognosis values
- (2022) Ying Liu et al. Frontiers in Genetics
- High-Affinity Cu(I)-Chelator with Potential Anti-Tumorigenic Action—A Proof-of-Principle Experimental Study of Human H460 Tumors in the CAM Assay
- (2022) Dorothea M. Heuberger et al. Cancers
- Copper-Dependent Kinases and Their Role in Cancer Inception, Progression and Metastasis
- (2022) Alessandra Vitaliti et al. Biomolecules
- A Novel Cuproptosis-Related Signature Identified DLAT as a Prognostic Biomarker for Hepatocellular Carcinoma Patients
- (2022) Wen Dong Bai et al. World Journal of Oncology
- Current and future burden of breast cancer: Global statistics for 2020 and 2040
- (2022) Melina Arnold et al. BREAST
- Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-Mutant Pancreatic Cancer
- (2022) Craig M. Goodwin et al. CANCER RESEARCH
- Proteomics revealed the crosstalk between copper stress and cuproptosis, and explored the feasibility of curcumin as anticancer copper ionophore
- (2022) Ying Yang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research
- (2022) Xuhui Tong et al. Journal of Hematology & Oncology
- Insights into prognosis and immune infiltration of cuproptosis-related genes in breast cancer
- (2022) Tingting Huang et al. Frontiers in Immunology
- Multi-omics pan-cancer study of cuproptosis core gene FDX1 and its role in kidney renal clear cell carcinoma
- (2022) Jiahao Xu et al. Frontiers in Immunology
- Relationship between copper and immunity: The potential role of copper in tumor immunity
- (2022) Fu Cheng et al. Frontiers in Oncology
- Cancer Statistics, 2021
- (2021) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- The role of macrophage in regulating tumour microenvironment and the strategies for reprogramming tumour-associated macrophages in antitumour therapy
- (2021) Liping Xu et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- A Phase 1 dose-escalation study of disulfiram and copper gluconate in patients with advanced solid tumors involving the liver using S-glutathionylation as a biomarker
- (2021) Kristen C. Kelley et al. BMC CANCER
- Copper biology
- (2021) Tiffany Tsang et al. CURRENT BIOLOGY
- The molecular and cellular basis of copper dysregulation and its relationship with human pathologies
- (2021) May T. Maung et al. FASEB JOURNAL
- Elesclomol-induced increase of mitochondrial reactive oxygen species impairs glioblastoma stem-like cell survival and tumor growth
- (2021) Mariachiara Buccarelli et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Determining PD-L1 Status in Patients With Triple-Negative Breast Cancer: Lessons Learned From IMpassion130
- (2021) Sunil S Badve et al. JNCI-Journal of the National Cancer Institute
- Elesclomol induces copper‐dependent ferroptosis in colorectal cancer cells via degradation of ATP7A
- (2021) Wei Gao et al. Molecular Oncology
- Tetrathiomolybdate (TM)-associated copper depletion influences collagen remodeling and immune response in the pre-metastatic niche of breast cancer
- (2021) Ying L. Liu et al. npj Breast Cancer
- Copper complexes as antitumor agents: in vitro and in vivo evidences
- (2021) Lucia M. Balsa et al. CURRENT MEDICINAL CHEMISTRY
- The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation
- (2021) Michael Grasso et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interference between copper transport systems and platinum drugs
- (2021) Fabio Arnesano et al. SEMINARS IN CANCER BIOLOGY
- Disulfiram Improves the Anti-PD-1 Therapy Efficacy by Regulating PD-L1 Expression via Epigenetically Reactivation of IRF7 in Triple Negative Breast Cancer
- (2021) Xin Zheng et al. Frontiers in Oncology
- The combination of disulfiram and copper for cancer treatment
- (2020) Hong Li et al. DRUG DISCOVERY TODAY
- Emerging New Concepts of Degrader Technologies
- (2020) Yu Ding et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- CDKN2A inhibits cell proliferation and invasion in cervical cancer through LDHA-mediated AKT/mTOR pathway
- (2020) Y. Luan et al. Clinical & Translational Oncology
- The molecular mechanisms of copper metabolism and its roles in human diseases
- (2020) Ji Chen et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model
- (2020) Brittney S. Harrington et al. Cancers
- Copper metabolism as a unique vulnerability in cancer
- (2020) Vinit C. Shanbhag et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
- (2020) Florida Voli et al. CANCER RESEARCH
- Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity
- (2020) Choong-Hwan Kwak et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial copper depletion suppresses triple-negative breast cancer in mice
- (2020) Liyang Cui et al. NATURE BIOTECHNOLOGY
- The Multifaceted Roles of Copper in Cancer: A Trace Metal Element with Dysregulated Metabolism, but Also a Target or a Bullet for Therapy
- (2020) Pierre Lelièvre et al. Cancers
- Disulfiram Chelated With Copper Inhibits the Growth of Gastric Cancer Cells by Modulating Stress Response and Wnt/β-catenin Signaling
- (2020) Ling Wang et al. Frontiers in Oncology
- A multicenter phase II study of temozolomide plus disulfiram and copper for recurrent temozolomide-resistant glioblastoma
- (2019) Jiayi Huang et al. JOURNAL OF NEURO-ONCOLOGY
- Mitochondrial metabolism promotes adaptation to proteotoxic stress
- (2019) Peter Tsvetkov et al. Nature Chemical Biology
- Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans
- (2019) Min Ni et al. Cell Reports
- Dichloroacetate (DCA) and Cancer: An Overview towards Clinical Applications
- (2019) Tiziana Tataranni et al. Oxidative Medicine and Cellular Longevity
- PDHA1 Gene Knockout In Human Esophageal Squamous Cancer Cells Resulted In Greater Warburg Effect And Aggressive Features In Vitro And In Vivo
- (2019) Lan Liu et al. OncoTargets and Therapy
- The role of glycolysis and mitochondrial respiration in the formation and functioning of endothelial tip cells during angiogenesis
- (2019) Bahar Yetkin-Arik et al. Scientific Reports
- Recent advances in the delivery of disulfiram: a critical analysis of promising approaches to improve its pharmacokinetic profile and anticancer efficacy
- (2019) Muhammad Asim Farooq et al. DARU-Journal of Pharmaceutical Sciences
- Mitochondrial oxidative stress as a novel therapeutic target to overcome intrinsic drug resistance in melanoma cell subpopulations
- (2015) Monika Cierlitza et al. EXPERIMENTAL DERMATOLOGY
- Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy
- (2015) Helen HW Chen et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- A Phase IIb Trial Assessing the Addition of Disulfiram to Chemotherapy for the Treatment of Metastatic Non-Small Cell Lung Cancer
- (2015) H. Nechushtan et al. ONCOLOGIST
- The oncoprotein HBXIP promotes glucose metabolism reprogramming via downregulating SCO2 and PDHA1 in breast cancer
- (2015) Fabao Liu et al. Oncotarget
- 5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits
- (2015) Corti Denise et al. Oncotarget
- The Pyruvate Dehydrogenase Complexes: Structure-based Function and Regulation
- (2014) Mulchand S. Patel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Copper is required for oncogenic BRAF signalling and tumorigenesis
- (2014) Donita C. Brady et al. NATURE
- Final Results of Phase III SYMMETRY Study: Randomized, Double-Blind Trial of Elesclomol Plus Paclitaxel Versus Paclitaxel Alone As Treatment for Chemotherapy-Naive Patients With Advanced Melanoma
- (2013) Steven J. O'Day et al. JOURNAL OF CLINICAL ONCOLOGY
- Copper Modulates Zinc Metalloproteinase-Dependent Ectodomain Shedding of Key Signaling and Adhesion Proteins and Promotes the Invasion of Prostate Cancer Epithelial Cells
- (2012) C. A. Parr-Sturgess et al. MOLECULAR CANCER RESEARCH
- Phase II, Randomized, Controlled, Double-Blinded Trial of Weekly Elesclomol Plus Paclitaxel Versus Paclitaxel Alone for Stage IV Metastatic Melanoma
- (2009) Steven O'Day et al. JOURNAL OF CLINICAL ONCOLOGY
- Mice with heterozygous deficiency of lipoic acid synthase have an increased sensitivity to lipopolysaccharide-induced tissue injury
- (2008) X. Yi et al. JOURNAL OF LEUKOCYTE BIOLOGY
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