Tetrathiomolybdate (TM)-associated copper depletion influences collagen remodeling and immune response in the pre-metastatic niche of breast cancer

Estrogen and Progesterone Receptor Testing in Breast Cancer: ASCO/CAP Guideline Update

(2020) Kimberly H. Allison et al.   JOURNAL OF CLINICAL ONCOLOGY

Nanoparticle Delivery of miR-708 Mimetic Impairs Breast Cancer Metastasis

(2019) Divya Ramchandani et al.   MOLECULAR CANCER THERAPEUTICS

High turnover of extracellular matrix reflected by specific protein fragments measured in serum is associated with poor outcomes in two metastatic breast cancer cohorts

(2018) Allan Lipton et al.   INTERNATIONAL JOURNAL OF CANCER

Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix

(2018) Stephanie N. Kehlet et al.   PLoS One

Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer

(2018) Peter Schmid et al.   NEW ENGLAND JOURNAL OF MEDICINE

Defining the human copper proteome and analysis of its expression variation in cancers

(2017) S. Blockhuys et al.   Metallomics

Structural ECM components in the premetastatic and metastatic niche

(2016) Anette M. Høye et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

From transformation to metastasis: deconstructing the extracellular matrix in breast cancer

(2016) Shelly Kaushik et al.   CANCER AND METASTASIS REVIEWS

Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in Preclinical Models of Lung Metastases

(2016) Nancy Chan et al.   CLINICAL CANCER RESEARCH

Cancer Tills the Premetastatic Field: Mechanistic Basis and Clinical Implications

(2016) A. R. Chin et al.   CLINICAL CANCER RESEARCH

Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers

(2016) Roni Allaoui et al.   Nature Communications

Excessive collagen turnover products are released during colorectal cancer progression and elevated in serum from metastatic colorectal cancer patients

(2016) S. N. Kehlet et al.   Scientific Reports

Breast cancer statistics, 2015: Convergence of incidence rates between black and white women

(2015) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Collagen degradation products measured in serum can separate ovarian and breast cancer patients from healthy controls: A preliminary study

(2015) C.L. Bager et al.   Cancer Biomarkers

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis

(2015) Bo Ri Seo et al.   Science Translational Medicine

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

NFATc1 Regulates PD-1 Expression upon T Cell Activation

(2014) K. J. Oestreich et al.   JOURNAL OF IMMUNOLOGY

Copper is required for oncogenic BRAF signalling and tumorigenesis

(2014) Donita C. Brady et al.   NATURE

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Extracellular matrix components in breast cancer progression and metastasis

(2013) Thordur Oskarsson   BREAST

LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis

(2013) T. R. Cox et al.   CANCER RESEARCH

MMP Mediated Degradation of Type IV Collagen Alpha 1 and Alpha 3 Chains Reflects Basement Membrane Remodeling in Experimental and Clinical Fibrosis – Validation of Two Novel Biomarker Assays

(2013) Jannie Marie Sand et al.   PLoS One

Collagen as a double-edged sword in tumor progression

(2013) Min Fang et al.   TUMOR BIOLOGY

Lysyl Oxidase Plays a Critical Role in Endothelial Cell Stimulation to Drive Tumor Angiogenesis

(2012) A.-M. Baker et al.   CANCER RESEARCH

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors

(2012) Hélène Salmon et al.   JOURNAL OF CLINICAL INVESTIGATION

A novel marker for assessment of liver matrix remodeling: An enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M)

(2011) DJ. Leeming et al.   BIOMARKERS

Incremental increase in VEGFR1+ hematopoietic progenitor cells and VEGFR2+ endothelial progenitor cells predicts relapse and lack of tumor response in breast cancer patients

(2011) Sarika Jain et al.   BREAST CANCER RESEARCH AND TREATMENT

MMP Mediated Degradation of Type VI Collagen Is Highly Associated with Liver Fibrosis – Identification and Validation of a Novel Biochemical Marker Assay

(2011) Sanne Skovgård Veidal et al.   PLoS One

Dynamic interplay between the collagen scaffold and tumor evolution

(2010) Mikala Egeblad et al.   CURRENT OPINION IN CELL BIOLOGY

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

Antiangiogenic Tetrathiomolybdate Protects against Her2/neu-Induced Breast Carcinoma by Hypoplastic Remodeling of the Mammary Gland

(2009) Q. Pan et al.   CLINICAL CANCER RESEARCH

Treatment of Wilson's disease with tetrathiomolybdate: V. control of free copper by tetrathiomolybdate and a comparison with trientine

(2009) George J. Brewer et al.   Translational Research

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER