CDKN2A inhibits cell proliferation and invasion in cervical cancer through LDHA-mediated AKT/mTOR pathway

Tumor Suppressors RB1 and CDKN2a Cooperatively Regulate Cell-Cycle Progression and Differentiation During Cardiomyocyte Development and Repair: Implications for Stimulating Neomyogenesis with Cell-Based Therapy

(2019) Konstantinos E Hatzistergos et al.   CIRCULATION RESEARCH

MTA1 coregulator regulates LDHA expression and function in breast cancer

(2019) Rohith Kumar Guddeti et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clinical and prognostic effects of CDKN2A, CDKN2B and CDH13 promoter methylation in ovarian cancer: a study using meta-analysis and TCGA data

(2019) Liang Xia et al.   BIOMARKERS

Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation

(2018) Hanlin Zeng et al.   CANCER CELL

Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival

(2018) Gaurav Pathria et al.   EMBO JOURNAL

T7 Peptide-Conjugated Lipid Nanoparticles for Dual Modulation of Bcl-2 and Akt-1 in Lung and Cervical Carcinomas

(2018) Xinwei Cheng et al.   MOLECULAR PHARMACEUTICS

CDKN2A/P16INK4A variants association with breast cancer and their in-silico analysis

(2018) Ayesha Aftab et al.   Breast Cancer

Regulation of Tumor Suppressor Gene CDKN2A and Encoded p16-INK4a Protein by Covalent Modifications

(2018) Yang Jiao et al.   BIOCHEMISTRY-MOSCOW

Dysregulated expression of long noncoding RNAs in gynecologic cancers

(2017) Elahe Seyed Hosseini et al.   Molecular Cancer

miR-663 promotes NPC cell proliferation by directly targeting CDKN2A

(2017) Shaoqiang Liang et al.   Molecular Medicine Reports

Clinical Benefit in Response to Palbociclib Treatment in Refractory Uterine Leiomyosarcomas with a Common CDKN2A Alteration

(2017) Julia A. Elvin et al.   ONCOLOGIST

Lactate dehydrogenase A promotes the invasion and proliferation of pituitary adenoma

(2017) Jiayin An et al.   Scientific Reports

Inhibition of the PI3K/AKT/mTOR Pathway in Solid Tumors

(2016) Patricia Mucci LoRusso   JOURNAL OF CLINICAL ONCOLOGY

Differentiated exophytic vulvar intraepithelial lesions are genetically distinct from keratinizing squamous cell carcinomas and contain mutations in PIK3CA

(2016) Jaclyn C Watkins et al.   MODERN PATHOLOGY

MiR-21 modulates radiosensitivity of cervical cancer through inhibiting autophagy via the PTEN/Akt/HIF-1α feedback loop and the Akt-mTOR signaling pathway

(2016) Lili Song et al.   TUMOR BIOLOGY

CDKN2A-p53 mediated antitumor effect of Lupeol in head and neck cancer

(2016) Sayantan Bhattacharyya et al.   CELLULAR ONCOLOGY

Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21

(2015) Jun Zhang et al.   CANCER BIOLOGY & THERAPY

Loss-of-Function Mutations in the Cell-Cycle Control GeneCDKN2AImpact on Glucose Homeostasis in Humans

(2015) Aparna Pal et al.   DIABETES

Twist promotes reprogramming of glucose metabolism in breast cancer cells through PI3K/AKT and p53 signaling pathways

(2015) Li Yang et al.   Oncotarget

p16INK4A Represses Breast Stromal Fibroblasts Migration/Invasion and Their VEGF-A-dependent Promotion of Angiogenesis through Akt Inhibition

(2015) Mysoon M. Al-Ansari et al.   NEOPLASIA

Cyclovirobuxine D Induces Autophagy-Associated Cell Death via the Akt/mTOR Pathway in MCF-7 Human Breast Cancer Cells

(2014) Jing Lu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

LDHA is necessary for the tumorigenicity of esophageal squamous cell carcinoma

(2012) Feng Yao et al.   TUMOR BIOLOGY

Inhibition of Id proteins by a peptide aptamer induces cell-cycle arrest and apoptosis in ovarian cancer cells

(2010) D S Mern et al.   BRITISH JOURNAL OF CANCER