Proteomics revealed the crosstalk between copper stress and cuproptosis, and explored the feasibility of curcumin as anticancer copper ionophore

Copper induces cell death by targeting lipoylated TCA cycle proteins

(2022) Peter Tsvetkov et al.   SCIENCE

Cytotoxic urea Schiff base complexes for multidrug discovery as anticancer activity and low in vivo oral assessing toxicity

(2022) Lotfi M. Aroua et al.   Arabian Journal of Chemistry

The functional roles of TCA cycle metabolites in cancer

(2021) Joseph Eniafe et al.   ONCOGENE

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

(2021) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis

(2021) Divya Ramchandani et al.   Nature Communications

Formulation of gold nanoparticles with hibiscus and curcumin extracts induced anti-cancer activity

(2021) Sultan Akhtar et al.   Arabian Journal of Chemistry

Copper-dependent biological effects of particulate matter produced by brake systems on lung alveolar cells

(2020) Marina Figliuzzi et al.   ARCHIVES OF TOXICOLOGY

Clinical effects of curcumin in enhancing cancer therapy: A systematic review

(2020) Kamran Mansouri et al.   BMC CANCER

Mitochondrial copper depletion suppresses triple-negative breast cancer in mice

(2020) Liyang Cui et al.   NATURE BIOTECHNOLOGY

Evaluation of catacholase mimicking activity and apoptosis in human colorectal carcinoma cell line by activating mitochondrial pathway of copper(II) complex coupled with 2-(quinolin-8-yloxy)(methyl)benzonitrile and 8-hydroxyquinoline

(2020) Arif Ali et al.   BIOORGANIC CHEMISTRY

Antitumor effects of curcumin: A lipid perspective

(2019) Mehri Bemani Naeini et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A new function of copper zinc superoxide dismutase: as a regulatory DNA-binding protein in gene expression in response to intracellular hydrogen peroxide

(2019) Xiang Li et al.   NUCLEIC ACIDS RESEARCH

DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput

(2019) Vadim Demichev et al.   NATURE METHODS

Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography–mass spectrometry

(2018) Philipp Mertins et al.   Nature Protocols

Cellular copper homeostasis: current concepts on its interplay with glutathione homeostasis and its implication in physiology and human diseases

(2017) Ashima Bhattacharjee et al.   Metallomics

ReactomePA: an R/Bioconductor package for reactome pathway analysis and visualization

(2016) Guangchuang Yu et al.   Molecular BioSystems

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

Curcumin is a biologically active copper chelator with antitumor activity

(2016) Wei Zhang et al.   PHYTOMEDICINE

The Use of Variable Q1 Isolation Windows Improves Selectivity in LC–SWATH–MS Acquisition

(2015) Ying Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Wilson's disease and other neurological copper disorders

(2015) Oliver Bandmann et al.   LANCET NEUROLOGY

Targeting copper in cancer therapy: ‘Copper That Cancer’

(2015) Delphine Denoyer et al.   Metallomics

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

(2015) Jing Wang et al.   Nature Chemistry

Toxicity of Copper on Isolated Liver Mitochondria: Impairment at Complexes I, II, and IV Leads to Increased ROS Production

(2014) Mir-Jamal Hosseini et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

New Perspectives of Curcumin in Cancer Prevention

(2013) W. Park et al.   Cancer Prevention Research

Glutathione and modulation of cell apoptosis

(2012) Magdalena L. Circu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Copper: An essential metal in biology

(2011) Richard A. Festa et al.   CURRENT BIOLOGY

Curcumin nanoformulations: a future nanomedicine for cancer

(2011) Murali M. Yallapu et al.   DRUG DISCOVERY TODAY

Copper toxicity and the origin of bacterial resistance—new insights and applications

(2011) Christopher L. Dupont et al.   Metallomics

Roles of dioxins and heavy metals in cancer and neurological diseases using ROS-mediated mechanisms

(2010) José M. Matés et al.   FREE RADICAL BIOLOGY AND MEDICINE

Curcumin adds spice to the debate: lipid metabolism in liver disease

(2009) Annette Graham   BRITISH JOURNAL OF PHARMACOLOGY

Apoptosis and glutathione: beyond an antioxidant

(2009) R Franco et al.   CELL DEATH AND DIFFERENTIATION

Curcumin and cancer: An “old-age” disease with an “age-old” solution

(2008) Preetha Anand et al.   CANCER LETTERS

Influence of ABCB1 and ABCG2 polymorphisms on doxorubicin disposition in Asian breast cancer patients

(2008) Suman Lal et al.   CANCER SCIENCE

New Roles for Copper Metabolism in Cell Proliferation, Signaling, and Disease

(2008) Michelle L. Turski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms for copper acquisition, distribution and regulation

(2008) Byung-Eun Kim et al.   Nature Chemical Biology

Anti cancer effects of curcumin: cycle of life and death

(2008) Gaurisankar Sa et al.   Cell Division