Copper induces cell death by targeting lipoylated TCA cycle proteins
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Title
Copper induces cell death by targeting lipoylated TCA cycle proteins
Authors
Keywords
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Journal
SCIENCE
Volume 375, Issue 6586, Pages 1254-1261
Publisher
American Association for the Advancement of Science (AAAS)
Online
2022-03-18
DOI
10.1126/science.abf0529
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Note: Only part of the references are listed.- Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity
- (2021) Nicholas Raffa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systemic deletion of Atp7b modifies the hepatocytes’ response to copper overload in the mouse models of Wilson disease
- (2021) Abigael Muchenditsi et al. Scientific Reports
- TMTpro-18plex: The Expanded and Complete Set of TMTpro Reagents for Sample Multiplexing
- (2021) Jiaming Li et al. JOURNAL OF PROTEOME RESEARCH
- Biosynthesis of fluopsin C, a copper-containing antibiotic from Pseudomonas aeruginosa
- (2021) Jon B. Patteson et al. SCIENCE
- Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics.
- (2020) Devin K. Schweppe et al. JOURNAL OF PROTEOME RESEARCH
- Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma
- (2020) Tiffany Tsang et al. NATURE CELL BIOLOGY
- Targeting apoptosis in cancer therapy
- (2020) Benedito A. Carneiro et al. Nature Reviews Clinical Oncology
- Mitochondrial copper depletion suppresses triple-negative breast cancer in mice
- (2020) Liyang Cui et al. NATURE BIOTECHNOLOGY
- Improved Monoisotopic Mass Estimation for Deeper Proteome Coverage
- (2020) Ramin Rad et al. JOURNAL OF PROTEOME RESEARCH
- FIREWORKS: a bottom-up approach to integrative coessentiality network analysis
- (2020) David R Amici et al. Life Science Alliance
- Characterization and Optimization of Multiplexed Quantitative Analyses Using High-Field Asymmetric-Waveform Ion Mobility Mass Spectrometry
- (2019) Devin K. Schweppe et al. ANALYTICAL CHEMISTRY
- The molecular machinery of regulated cell death
- (2019) Daolin Tang et al. CELL RESEARCH
- Mitochondrial metabolism promotes adaptation to proteotoxic stress
- (2019) Peter Tsvetkov et al. Nature Chemical Biology
- Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans
- (2019) Min Ni et al. Cell Reports
- Emerging Opportunities To Manipulate Metal Trafficking for Therapeutic Benefit
- (2019) Elizabeth W. Hunsaker et al. INORGANIC CHEMISTRY
- ilastik: interactive machine learning for (bio)image analysis
- (2019) Stuart Berg et al. NATURE METHODS
- Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging
- (2019) Ziming Du et al. Nature Protocols
- Protein lipoylation: an evolutionarily conserved metabolic regulator of health and disease
- (2018) Elizabeth A Rowland et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Streamlined Tandem Mass Tag (SL-TMT) Protocol: An Efficient Strategy for Quantitative (Phospho)proteome Profiling Using Tandem Mass Tag-Synchronous Precursor Selection-MS3
- (2018) José Navarrete-Perea et al. JOURNAL OF PROTEOME RESEARCH
- Copper(I)-binding properties of de-coppering drugs for the treatment of Wilson disease. α-Lipoic acid as a potential anti-copper agent
- (2018) Julia Smirnova et al. Scientific Reports
- Lipoic acid metabolism and mitochondrial redox regulation
- (2017) Ashley Solmonson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- [4Fe-4S] Cluster Assembly in Mitochondria and Its Impairment by Copper
- (2017) Diego Brancaccio et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4
- (2017) Zdenek Skrott et al. NATURE
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- Necroptosis in development, inflammation and disease
- (2016) Ricardo Weinlich et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis
- (2015) Kıvanç Birsoy et al. CELL
- Wilson's disease and other neurological copper disorders
- (2015) Oliver Bandmann et al. LANCET NEUROLOGY
- Lipoic acid biosynthesis defects
- (2014) Johannes A. Mayr et al. JOURNAL OF INHERITED METABOLIC DISEASE
- The cytotoxicity of the anticancer drug elesclomol is due to oxidative stress indirectly mediated through its complex with Cu(II)
- (2014) Brian B. Hasinoff et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Final Results of Phase III SYMMETRY Study: Randomized, Double-Blind Trial of Elesclomol Plus Paclitaxel Versus Paclitaxel Alone As Treatment for Chemotherapy-Naive Patients With Advanced Melanoma
- (2013) Steven J. O'Day et al. JOURNAL OF CLINICAL ONCOLOGY
- Molecular mechanisms of the biological activity of the anticancer drug elesclomol and its complexes with Cu(II), Ni(II) and Pt(II)
- (2013) Arun A. Yadav et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Charting the travels of copper in eukaryotes from yeast to mammals
- (2012) Tracy Nevitt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells
- (2012) Masazumi Nagai et al. FREE RADICAL BIOLOGY AND MEDICINE
- Copper-Dependent Cytotoxicity of 8-Hydroxyquinoline Derivatives Correlates with Their Hydrophobicity and Does Not Require Caspase Activation
- (2012) Saverio Tardito et al. JOURNAL OF MEDICINAL CHEMISTRY
- Zinc Pyrithione Inhibits Yeast Growth through Copper Influx and Inactivation of Iron-Sulfur Proteins
- (2011) Nancy L. Reeder et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Disulfiram modulated ROS–MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties
- (2011) N C Yip et al. BRITISH JOURNAL OF CANCER
- Copper Binding Agents Acting as Copper Ionophores Lead to Caspase Inhibition and Paraptotic Cell Death in Human Cancer Cells
- (2011) Saverio Tardito et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Human copper homeostasis: a network of interconnected pathways
- (2010) Svetlana Lutsenko CURRENT OPINION IN CHEMICAL BIOLOGY
- Copper Stress Affects Iron Homeostasis by Destabilizing Iron-Sulfur Cluster Formation in Bacillus subtilis
- (2010) S. Chillappagari et al. JOURNAL OF BACTERIOLOGY
- Phase II, Randomized, Controlled, Double-Blinded Trial of Weekly Elesclomol Plus Paclitaxel Versus Paclitaxel Alone for Stage IV Metastatic Melanoma
- (2009) Steven O'Day et al. JOURNAL OF CLINICAL ONCOLOGY
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
- The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity
- (2009) L. Macomber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Atp7b−/−mice as a model for studies of Wilson's disease
- (2008) Svetlana Lutsenko BIOCHEMICAL SOCIETY TRANSACTIONS
- Elesclomol induces cancer cell apoptosis through oxidative stress
- (2008) J. R. Kirshner et al. MOLECULAR CANCER THERAPEUTICS
- Mechanisms for copper acquisition, distribution and regulation
- (2008) Byung-Eun Kim et al. Nature Chemical Biology
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