High-Affinity Cu(I)-Chelator with Potential Anti-Tumorigenic Action—A Proof-of-Principle Experimental Study of Human H460 Tumors in the CAM Assay

Copper(II) N,N,O-Chelating Complexes as Potential Anticancer Agents

(2021) Quim Peña et al.   INORGANIC CHEMISTRY

Lung cancer

(2021) Alesha A Thai et al.   LANCET

Copper Promotes Tumorigenesis by Activating the PDK1‐AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner

(2021) Jianping Guo et al.   Advanced Science

Multifunctional Copper-Containing Mesoporous Glass Nanoparticles as Antibacterial and Proangiogenic Agents for Chronic Wounds

(2020) Thomas E. Paterson et al.   Frontiers in Bioengineering and Biotechnology

Cancer Pro-oxidant Therapy Through Copper Redox Cycling: Repurposing Disulfiram and Tetrathiomolybdate

(2020) Manuel Rieber   CURRENT PHARMACEUTICAL DESIGN

Effects of Zinc Oxide Nanoparticles in HUVEC: Cyto- and Genotoxicity and Functional Impairment After Long-Term and Repetitive Exposure in vitro

(2020) Nikolaus Poier et al.   International Journal of Nanomedicine

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

(2020) Léo Aubert et al.   Nature Communications

Targeting tumor hypoxia and mitochondrial metabolism with anti-parasitic drugs to improve radiation response in high-grade gliomas

(2020) Faiqa Mudassar et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Serum Copper Level and the Copper-to-Zinc Ratio Could Be Useful in the Prediction of Lung Cancer and Its Prognosis: A Case-Control Study in Northeast China

(2020) Wenjun Wang et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Serum copper and zinc levels in breast cancer: A meta-analysis

(2020) Yue Feng et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Microvascular density and hypoxia-inducible factor in intraepithelial vocal fold lesions

(2019) Anna Rzepakowska et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Ratiometric two-photon microscopy reveals attomolar copper buffering in normal and Menkes mutant cells

(2019) M. Thomas Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contrast-enhanced Ultrasound in evaluating of angiogenesis and tumor staging of nasopharyngeal carcinoma in nude mice

(2019) ShouJun Liang et al.   PLoS One

High-affinity Cu(I) chelator PSP-2 as potential anti-angiogenic agent

(2019) Dorothea M. Heuberger et al.   Scientific Reports

Systematic analysis of concentrations of 52 elements in tumor and counterpart normal tissues of patients with non‐small cell lung cancer

(2019) Xin Cheng et al.   Cancer Medicine

Stabilization of Aliphatic Phosphines by Auxiliary Phosphine Sulfides Offers Zeptomolar Affinity and Unprecedented Selectivity for Probing Biological CuI

(2018) M. Thomas Morgan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cellular self-assembly into 3D microtissues enhances the angiogenic activity and functional neovascularization capacity of human cardiopoietic stem cells

(2018) Petra Wolint et al.   ANGIOGENESIS

Association between serum copper levels and lung cancer risk: A meta-analysis

(2018) Xiaping Zhang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Hypoxia and HIF pathway in cancer and the placenta

(2017) Philip S. Macklin et al.   PLACENTA

Heteroleptic Copper(I) Complexes of “Scorpionate” Bis-pyrazolyl Carboxylate Ligand with Auxiliary Phosphine as Potential Anticancer Agents: An Insight into Cytotoxic Mode

(2017) Rais Ahmad Khan et al.   Scientific Reports

Copper transporters and chaperones: Their function on angiogenesis and cellular signalling

(2016) S R Bharathi Devi et al.   JOURNAL OF BIOSCIENCES

Hypoxia-inducible factors: a central link between inflammation and cancer

(2016) Daniel Triner et al.   JOURNAL OF CLINICAL INVESTIGATION

Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics

(2016) Kyung Chan Park et al.   Metallomics

Graphene Oxide-Copper Nanocomposite-Coated Porous CaP Scaffold for Vascularized Bone Regeneration via Activation of Hif-1α

(2016) Wenjie Zhang et al.   Advanced Healthcare Materials

Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice

(2015) Jae-Hwi Jang et al.   CLINICAL & EXPERIMENTAL METASTASIS

Pharmacological activity of metal binding agents that alter copper bioavailability

(2015) Marian E. Helsel et al.   DALTON TRANSACTIONS

Vascular endothelial growth factor directly stimulates tumour cell proliferation in non-small cell lung cancer

(2015) AOIFE M. DEVERY et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Lysyl Oxidase Activity Is Required for Ordered Collagen Fibrillogenesis by Tendon Cells

(2015) Andreas Herchenhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Behind the Link between Copper and Angiogenesis: Established Mechanisms and an Overview on the Role of Vascular Copper Transport Systems

(2015) Emanuela Urso et al.   JOURNAL OF VASCULAR RESEARCH

Homoleptic phosphino copper(i) complexes with in vitro and in vivo dual cytotoxic and anti-angiogenic activity

(2015) V. Gandin et al.   Metallomics

Targeting copper in cancer therapy: ‘Copper That Cancer’

(2015) Delphine Denoyer et al.   Metallomics

A NewIn VivoMagnetic Resonance Imaging Method to Noninvasively Monitor and Quantify the Perfusion Capacity of Three-Dimensional Biomaterials Grown on the Chorioallantoic Membrane of Chick Embryos

(2015) Fatma Kivrak Pfiffner et al.   TISSUE ENGINEERING PART C-METHODS

Copper is required for oncogenic BRAF signalling and tumorigenesis

(2014) Donita C. Brady et al.   NATURE

Oxidative stress in angiogenesis and vascular disease

(2013) Y.-W. Kim et al.   BLOOD

Rapid Copper Acquisition by Developing Murine Mesothelioma: Decreasing Bioavailable Copper Slows Tumor Growth, Normalizes Vessels and Promotes T Cell Infiltration

(2013) Andrew Crowe et al.   PLoS One

Bioavailable copper modulates oxidative phosphorylation and growth of tumors

(2013) S. Ishida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Copper chelator ATN-224 inhibits endothelial function by multiple mechanisms

(2009) Sarah A. Lowndes et al.   MICROVASCULAR RESEARCH

Low-dose metronomic cyclophosphamide treatment mediates ischemia-dependent K-ras mutation in colorectal carcinoma xenografts

(2008) S Shahrzad et al.   ONCOGENE