Integrative metabolomics science in Alzheimer’s disease: Relevance and future perspectives
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Integrative metabolomics science in Alzheimer’s disease: Relevance and future perspectives
Authors
Keywords
-
Journal
AGEING RESEARCH REVIEWS
Volume 89, Issue -, Pages 101987
Publisher
Elsevier BV
Online
2023-06-19
DOI
10.1016/j.arr.2023.101987
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?
- (2023) Richard J. Johnson et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- The foundation and architecture of precision medicine in neurology and psychiatry
- (2023) Harald Hampel et al. TRENDS IN NEUROSCIENCES
- Recent advances in mass spectrometry-based computational metabolomics
- (2023) Timothy M.D. Ebbels et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- The identification of a potential plasma metabolite marker for Alzheimer’s disease by LC-MS untargeted metabolomics
- (2023) Chieh-Hsin Lin et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Advances and perspectives in chemical isotope labeling-based mass spectrometry methods for metabolome and exposome analysis
- (2023) Shuo Gao et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Advances in mass spectrometry-based single-cell metabolite analysis
- (2023) Bohong Wang et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Integrated multi-omics analysis of Alzheimer’s disease shows molecular signatures associated with disease progression and potential therapeutic targets
- (2023) Pradeep Kodam et al. Scientific Reports
- Ketogenic interventions in mild cognitive impairment, Alzheimer's disease, and Parkinson's disease: A systematic review and critical appraisal
- (2023) Jeffrey L. B. Bohnen et al. Frontiers in Neurology
- The Role of Tryptophan Metabolism in Alzheimer’s Disease
- (2023) Karl Savonije et al. Brain Sciences
- Relationship between Expression of Plasma lncRNA-HEIH and Prognosis in Patients with Coronary Artery Disease
- (2022) Zhenying Zhang et al. DISEASE MARKERS
- Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise
- (2022) Fei Yin FEBS Journal
- Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline
- (2022) Raúl González-Domínguez et al. Alzheimers Research & Therapy
- Identification and Distribution of Sterols, Bile Acids, and Acylcarnitines by LC–MS/MS in Humans, Mice, and Pigs—A Qualitative Analysis
- (2022) Ambrin Farizah Babu et al. Metabolites
- Predictive metabolic networks reveal sex‐ and APOE genotype‐specific metabolic signatures and drivers for precision medicine in Alzheimer's disease
- (2022) Rui Chang et al. Alzheimers & Dementia
- Neurovascular coupling mechanisms in health and neurovascular uncoupling in Alzheimer’s disease
- (2022) Winston M. Zhu et al. BRAIN
- Glucose Metabolism, Neural Cell Senescence and Alzheimer’s Disease
- (2022) Qianqian Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Emerging Role of Phospholipids and Lysophospholipids for Improving Brain Docosahexaenoic Acid as Potential Preventive and Therapeutic Strategies for Neurological Diseases
- (2022) Mayssa Hachem et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques
- (2022) Ju-Hyun Lee et al. NATURE NEUROSCIENCE
- Glucose metabolism and AD: evidence for a potential diabetes type 3
- (2022) Andrea González et al. Alzheimers Research & Therapy
- Guide to Metabolomics Analysis: A Bioinformatics Workflow
- (2022) Yang Chen et al. Metabolites
- Endosomal-Lysosomal and Autophagy Pathway in Alzheimer’s Disease: A Systematic Review and Meta-Analysis
- (2022) Saffire H. Krance et al. JOURNAL OF ALZHEIMERS DISEASE
- High-resolution NMR metabolomics of patients with subjective cognitive decline plus: Perturbations in the metabolism of glucose and branched-chain amino acids
- (2022) Zhongxian Yang et al. NEUROBIOLOGY OF DISEASE
- Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease
- (2022) Abbas Dehghan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Whole-brain mapping of metabolic alterations in a mouse model of Alzheimer's disease by desorption electrospray ionization mass spectrometry imaging
- (2022) Xiaoqun Wang et al. TALANTA
- Plasma glycocholic acid and linoleic acid identified as potential mediators of mitochondrial bioenergetics in Alzheimer’s dementia
- (2022) K. Allison Amick et al. Frontiers in Aging Neuroscience
- Plasma Lipidomics Approach in Early and Specific Alzheimer’s Disease Diagnosis
- (2022) Carmen Peña-Bautista et al. Journal of Clinical Medicine
- Multi-Omics, an Integrated Approach to Identify Novel Blood Biomarkers of Alzheimer’s Disease
- (2022) Maxime François et al. Metabolites
- Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer’s disease
- (2022) Priyanka Baloni et al. Communications Biology
- Brain region‐specific metabolic signatures of Alzheimer’s disease
- (2022) Richa Batra et al. Alzheimers & Dementia
- Omics-based biomarkers discovery for Alzheimer's disease
- (2022) Qiaolifan Aerqin et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- High spatial resolution mass spectrometry imaging for spatial metabolomics: Advances, challenges, and future perspectives
- (2022) Siyuan Ma et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Exploration of the Gut–Brain Axis through Metabolomics Identifies Serum Propionic Acid Associated with Higher Cognitive Decline in Older Persons
- (2022) Jeanne Neuffer et al. Nutrients
- Branched-Chain Amino Acids Are Linked with Alzheimer’s Disease-Related Pathology and Cognitive Deficits
- (2022) Md Abu Bakkar Siddik et al. Cells
- Altered Gut Microbial Metabolites in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease: Signals in Host–Microbe Interplay
- (2021) Li Wu et al. Nutrients
- Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics
- (2021) Giuseppe Paglia et al. MASS SPECTROMETRY REVIEWS
- Randomized crossover trial of a modified ketogenic diet in Alzheimer’s disease
- (2021) Matthew C. L. Phillips et al. Alzheimers Research & Therapy
- Plasma phosphatidylcholines and vitamin B12/folate levels are possible prognostic biomarkers for progression of Alzheimer's disease
- (2021) Imrich Blasko et al. EXPERIMENTAL GERONTOLOGY
- Calcium Dyshomeostasis in Alzheimer’s Disease Pathogenesis
- (2021) Roberta Cascella et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cerebrospinal Fluid C18 Ceramide Associates with Markers of Alzheimer’s Disease and Inflammation at the Pre- and Early Stages of Dementia
- (2021) Unnur D. Teitsdottir et al. JOURNAL OF ALZHEIMERS DISEASE
- Endosomal‐lysosomal dysfunctions in Alzheimer’s disease: Pathogenesis and therapeutic interventions
- (2021) Shereen Shi Min Lai et al. METABOLIC BRAIN DISEASE
- Hyperhomocysteinemia-related serum metabolome alterations not normalized by short-term folic acid treatment
- (2021) A. Aneesh Kumar et al. Metabolomics
- Differential effects of alkaloids on memory in rodents
- (2021) Patrick M. Callahan et al. Scientific Reports
- Glucose metabolism in the right middle temporal gyrus could be a potential biomarker for subjective cognitive decline: a study of a Han population
- (2021) Qiu-Yue Dong et al. Alzheimers Research & Therapy
- Mechanistic Insights into Alzheimer’s Disease Unveiled through the Investigation of Disturbances in Central Metabolites and Metabolic Pathways
- (2021) Raúl González-Domínguez et al. Biomedicines
- Multi-Layer Picture of Neurodegenerative Diseases: Lessons from the Use of Big Data through Artificial Intelligence
- (2021) Andrea Termine et al. Journal of Personalized Medicine
- Omics sciences for systems biology in Alzheimer’s disease: State-of-the-art of the evidence
- (2021) Harald Hampel et al. AGEING RESEARCH REVIEWS
- Metabolomic Alterations in the Blood and Brain in Association with Alzheimer’s Disease: Evidence from in vivo to Clinical Studies
- (2021) Sirawit Sriwichaiin et al. JOURNAL OF ALZHEIMERS DISEASE
- A Review of Oxidative Stress Products and Related Genes in Early Alzheimer’s Disease
- (2021) Federica Cioffi et al. JOURNAL OF ALZHEIMERS DISEASE
- Plasma Sphingomyelins in Late-Onset Alzheimer’s Disease
- (2021) Gianna Fote et al. JOURNAL OF ALZHEIMERS DISEASE
- Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's disease
- (2021) D. O. T. Alawode et al. JOURNAL OF INTERNAL MEDICINE
- Metabolic Profiling of Neocortical Tissue Discriminates Alzheimer’s Disease from Mild Cognitive Impairment, High Pathology Controls, and Normal Controls
- (2021) Paniz Jasbi et al. JOURNAL OF PROTEOME RESEARCH
- Challenges in LC–MS-based metabolomics for Alzheimer’s disease early detection: targeted approaches versus untargeted approaches
- (2021) Pierluigi Reveglia et al. Metabolomics
- Developing the ATX(N) classification for use across the Alzheimer disease continuum
- (2021) Harald Hampel et al. Nature Reviews Neurology
- MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
- (2021) Zhiqiang Pang et al. NUCLEIC ACIDS RESEARCH
- Whole-blood metabolomics of dementia patients reveal classes of disease-linked metabolites
- (2021) Takayuki Teruya et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes
- (2021) Yue Liu et al. Translational Psychiatry
- Erythrocyte sphingolipid species as biomarkers of Alzheimer's disease
- (2021) Jericha Mill et al. Journal of Pharmaceutical Analysis
- Mitochondrial dysfunction, oxidative stress, neuroinflammation, and metabolic alterations in the progression of Alzheimer’s disease: A meta-analysis of in vivo magnetic resonance spectroscopy studies
- (2021) Tao Song et al. AGEING RESEARCH REVIEWS
- Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease
- (2021) Emrin Horgusluoglu et al. Alzheimers & Dementia
- Plasma metabolomic profiling of hypertrophic cardiomyopathy patients before and after surgical myectomy suggests postoperative improvement in metabolic function
- (2021) Nicole L. Wolter et al. BMC Cardiovascular Disorders
- Plasma metabolomic profiling in subclinical atherosclerosis: the Diabetes Heart Study
- (2021) Parag Anilkumar Chevli et al. Cardiovascular Diabetology
- Metabolomic Profiling of Blood-Derived Microvesicles in Breast Cancer Patients
- (2021) Judith Buentzel et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Association of Lipidomics Signatures in Blood with Clinical Progression in Preclinical and Prodromal Alzheimer’s Disease
- (2021) Fatemah Sakr et al. JOURNAL OF ALZHEIMERS DISEASE
- Current state-of-the-art of separation methods used in LC-MS based metabolomics and lipidomics
- (2021) Eva-Maria Harrieder et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Food and Microbiota Metabolites Associate with Cognitive Decline in Older Subjects: A 12‐Year Prospective Study
- (2021) Raúl González‐Domínguez et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Emerging roles of oxidative stress in brain aging and Alzheimer's disease
- (2021) Andra Ionescu-Tucker et al. NEUROBIOLOGY OF AGING
- Alterations in Glycerolipid and Fatty Acid Metabolic Pathways in Alzheimer's Disease Identified by Urinary Metabolic Profiling: A Pilot Study
- (2021) Yumi Watanabe et al. Frontiers in Neurology
- Lipid Profiling of Alzheimer’s Disease Brain Highlights Enrichment in Glycerol(phospho)lipid, and Sphingolipid Metabolism
- (2021) Sumeyya Akyol et al. Cells
- Lipids and Alzheimer’s Disease
- (2020) Yu-Chia Kao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome
- (2020) Matthias Arnold et al. Nature Communications
- The clinical promise of biomarkers of synapse damage or loss in Alzheimer’s disease
- (2020) Martí Colom-Cadena et al. Alzheimers Research & Therapy
- Mitochondria-Targeted Therapeutics for Alzheimer's Disease: The Good, the Bad, the Potential
- (2020) Yashi Mi et al. ANTIOXIDANTS & REDOX SIGNALING
- A Placebo-Controlled, Parallel-Group, Randomized Clinical Trial of AC-1204 in Mild-to-Moderate Alzheimer’s Disease
- (2020) Samuel T. Henderson et al. JOURNAL OF ALZHEIMERS DISEASE
- Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances
- (2020) Wenzhang Wang et al. Molecular Neurodegeneration
- The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeutics
- (2020) Sarah A. Kent et al. ACTA NEUROPATHOLOGICA
- Blood fatty acids in Alzheimer’s disease and mild cognitive impairment: A meta-analysis and systematic review
- (2020) Mahboobeh Hosseini et al. AGEING RESEARCH REVIEWS
- Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis
- (2020) Germán Plascencia-Villa et al. ANTIOXIDANTS & REDOX SIGNALING
- Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease
- (2020) Tiantian Guo et al. Molecular Neurodegeneration
- Aging and Progression of Beta-Amyloid Pathology in Alzheimer’s Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression
- (2020) Cristina Fernández-Mendívil et al. Antioxidants
- Characterization of the Human Exposome by a Comprehensive and Quantitative Large-Scale Multianalyte Metabolomics Platform
- (2020) Raúl González-Domínguez et al. ANALYTICAL CHEMISTRY
- Metabolomic profiling of patients with high gradient aortic stenosis undergoing transcatheter aortic valve replacement
- (2020) Daniela Haase et al. Clinical Research in Cardiology
- Vascular dysfunction—The disregarded partner of Alzheimer's disease
- (2019) Melanie D. Sweeney et al. Alzheimers & Dementia
- Acute glucose fluctuation impacts microglial activity, leading to inflammatory activation or self-degradation
- (2019) Cheng-Fang Hsieh et al. Scientific Reports
- Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
- (2019) D. Allan Butterfield et al. NATURE REVIEWS NEUROSCIENCE
- Nucleotides regulate the common molecular mechanisms that underlie neurodegenerative diseases; Therapeutic implications
- (2019) Álvaro Sebastián-Serrano et al. BRAIN RESEARCH BULLETIN
- Blood-based molecular signature of Alzheimer's disease via spectroscopy and metabolomics
- (2019) Lucie Habartová et al. CLINICAL BIOCHEMISTRY
- Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities–Neurocognitive Study (ARIC-NCS)
- (2019) Danni Li et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial dynamics and transport in Alzheimer's disease
- (2019) Padraig J. Flannery et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Diet‐Related Metabolites Associated with Cognitive Decline Revealed by Untargeted Metabolomics in a Prospective Cohort
- (2019) Dorrain Yanwen Low et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies
- (2019) Yu Yamazaki et al. Nature Reviews Neurology
- Endo-lysosomal pathway and ubiquitin-proteasome system dysfunction in Alzheimer's disease pathogenesis
- (2019) Jiqing Cao et al. NEUROSCIENCE LETTERS
- Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity
- (2019) Oleksandr Yagensky et al. eLife
- Multi-omics signature of brain amyloid deposition in asymptomatic individuals at-risk for Alzheimer's disease: The INSIGHT-preAD study
- (2019) Laura Xicota et al. EBioMedicine
- Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
- (2019) Justin M. Long et al. CELL
- Recent advances from metabolomics and lipidomics application in alzheimer’s disease inspiring drug discovery
- (2019) Miroslava Cuperlovic-Culf et al. Expert Opinion on Drug Discovery
- The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease
- (2019) Alessandra Webers et al. IMMUNOLOGY AND CELL BIOLOGY
- The complement cascade in Alzheimer’s disease: a systematic review and meta-analysis
- (2019) Saffire H. Krance et al. MOLECULAR PSYCHIATRY
- Brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis
- (2019) Zhiguang Huo et al. NEUROBIOLOGY OF AGING
- Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium
- (2019) Ashley van der Spek et al. Scientific Reports
- High‐resolution metabolomic profiling of Alzheimer’s disease in plasma
- (2019) Megan M. Niedzwiecki et al. Annals of Clinical and Translational Neurology
- Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts
- (2018) Juho Tynkkynen et al. Alzheimers & Dementia
- Evidence for brain glucose dysregulation in Alzheimer's disease
- (2018) Yang An et al. Alzheimers & Dementia
- Autonomous Multimodal Metabolomics Data Integration for Comprehensive Pathway Analysis and Systems Biology
- (2018) Tao Huan et al. ANALYTICAL CHEMISTRY
- LipidPedia: a comprehensive lipid knowledgebase
- (2018) Tien-Chueh Kuo et al. BIOINFORMATICS
- Diacylglycerols as biomarkers of sustained immune activation in Proteinopathies associated with dementia
- (2018) Paul L. Wood et al. CLINICA CHIMICA ACTA
- Toward Reproducible Results from Targeted Metabolomic Studies: Perspectives for Data Pre-Processing and a Basis for Analytic Pipeline Development
- (2018) Thomas Gross et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Religious Orders Study and Rush Memory and Aging Project
- (2018) David A. Bennett et al. JOURNAL OF ALZHEIMERS DISEASE
- Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer’s Disease
- (2018) D. Allan Butterfield et al. JOURNAL OF ALZHEIMERS DISEASE
- Homocysteine and Dementia: An International Consensus Statement
- (2018) A. David Smith et al. JOURNAL OF ALZHEIMERS DISEASE
- Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders
- (2018) Katrin Augustin et al. LANCET NEUROLOGY
- Data processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online
- (2018) Erica M Forsberg et al. Nature Protocols
- Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study
- (2018) Vijay R. Varma et al. PLOS MEDICINE
- Magnetic resonance spectroscopy reveals abnormalities of glucose metabolism in the Alzheimer's brain
- (2018) Roger Mullins et al. Annals of Clinical and Translational Neurology
- Phosphorylation of different tau sites during progression of Alzheimer’s disease
- (2018) Joerg Neddens et al. Acta Neuropathologica Communications
- Alzheimer's disease and Type 2 Diabetes mellitus are distinct diseases with potential overlapping metabolic dysfunction upstream of observed cognitive decline
- (2018) Yevgen Chornenkyy et al. BRAIN PATHOLOGY
- Plasma Sphingomyelins are Associated with Cognitive Progression in Alzheimer's Disease
- (2018) Michelle M. Mielke et al. JOURNAL OF ALZHEIMERS DISEASE
- Sporadic Alzheimer's Disease: The Starving Brain
- (2018) Mortimer Mamelak JOURNAL OF ALZHEIMERS DISEASE
- Increased Ceramide in Brains with Alzheimer's and Other Neurodegenerative Diseases
- (2018) Valery Filippov et al. JOURNAL OF ALZHEIMERS DISEASE
- Next-generation biomarker discovery in Alzheimer's disease using metabolomics – from animal to human studies
- (2018) Marina Ollé Hurtado et al. Bioanalysis
- Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers
- (2018) Kwangsik Nho et al. Alzheimers & Dementia
- Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome
- (2018) Siamak MahmoudianDehkordi et al. Alzheimers & Dementia
- Generation and quality control of lipidomics data for the alzheimer’s disease neuroimaging initiative cohort
- (2018) Dinesh Kumar Barupal et al. Scientific Data
- Studies on diagnostic biomarkers and therapeutic mechanism of Alzheimer's disease through metabolomics and hippocampal proteomics
- (2017) Weiwei Lin et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Homocysteine concentrations in the cognitive progression of Alzheimer's disease
- (2017) Nicolas Farina et al. EXPERIMENTAL GERONTOLOGY
- Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline
- (2017) Stefano Tarantini et al. EXPERIMENTAL GERONTOLOGY
- The Association Between Plasma Ceramides and Sphingomyelins and Risk of Alzheimer’s Disease Differs by Sex and APOE in the Baltimore Longitudinal Study of Aging
- (2017) Michelle M. Mielke et al. JOURNAL OF ALZHEIMERS DISEASE
- A Critical Assessment of Research on Neurotransmitters in Alzheimer’s Disease
- (2017) P. Hemachandra Reddy JOURNAL OF ALZHEIMERS DISEASE
- Lipidomic Profiles in Diabetes and Dementia
- (2017) Kevin Huynh et al. JOURNAL OF ALZHEIMERS DISEASE
- Metabolomics in Alzheimer’s disease: The need of complementary analytical platforms for the identification of biomarkers to unravel the underlying pathology
- (2017) Raúl González-Domínguez et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Targeted metabolomics analysis of aromatic amino acids and their gut microbiota-host cometabolites in rat serum and urine by liquid chromatography coupled with tandem mass spectrometry
- (2017) Yifeng Zeng et al. JOURNAL OF SEPARATION SCIENCE
- Mass-spectrometry-based lipidomics
- (2017) Ting Hu et al. JOURNAL OF SEPARATION SCIENCE
- Bile acid quantification of 20 plasma metabolites identifies lithocholic acid as a putative biomarker in Alzheimer’s disease
- (2017) Josef Marksteiner et al. Metabolomics
- A robust, single-injection method for targeted, broad-spectrum plasma metabolomics
- (2017) Kefeng Li et al. Metabolomics
- Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites
- (2017) Tao Long et al. NATURE GENETICS
- Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role
- (2017) C. J. Garwood et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Metabolomics: A Primer
- (2017) Xiaojing Liu et al. TRENDS IN BIOCHEMICAL SCIENCES
- Plasma lipids metabolism in mild cognitive impairment and Alzheimer’s disease
- (2017) Alana C. Costa et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- Direct infusion mass spectrometry for metabolomic phenotyping of diseases
- (2017) Raúl González-Domínguez et al. Bioanalysis
- Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study
- (2017) Stuart G. Snowden et al. PLOS MEDICINE
- Association of Docosahexaenoic Acid Supplementation With Alzheimer Disease Stage in Apolipoprotein E ε4 Carriers
- (2017) Hussein N. Yassine et al. JAMA Neurology
- Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study
- (2017) J Bressler et al. Translational Psychiatry
- The Heme Degradation Pathway is a Promising Serum Biomarker Source for the Early Detection of Alzheimer's Disease
- (2017) Claudius Mueller et al. JOURNAL OF ALZHEIMERS DISEASE
- Recent advances in using mass spectrometry for mitochondrial metabolomics and lipidomics - A review
- (2017) Xinyu Liu et al. ANALYTICA CHIMICA ACTA
- Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals
- (2016) Ramon Casanova et al. Alzheimers & Dementia
- Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder
- (2016) Jingshu Xu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Metabolomic-Driven Elucidation of Serum Disturbances Associated with Alzheimer';s Disease and Mild Cognitive Impairment
- (2016) Raúl González-Domínguez et al. Current Alzheimer Research
- Asparagine endopeptidase is an innovative therapeutic target for neurodegenerative diseases
- (2016) Zhentao Zhang et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Metabolomics studies in brain tissue: A review
- (2016) Carolina Gonzalez-Riano et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Recent advances in liquid-phase separations for clinical metabolomics
- (2016) Isabelle Kohler et al. JOURNAL OF SEPARATION SCIENCE
- Metabolomics: beyond biomarkers and towards mechanisms
- (2016) Caroline H. Johnson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Medium-chain plasma acylcarnitines, ketone levels, cognition, and gray matter volumes in healthy elderly, mildly cognitively impaired, or Alzheimer's disease subjects
- (2016) Domenico Ciavardelli et al. NEUROBIOLOGY OF AGING
- APP Receptor? To Be or Not To Be
- (2016) Carole Deyts et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Analytical pitfalls and challenges in clinical metabolomics
- (2016) Isabelle Kohler et al. Bioanalysis
- Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
- (2016) Y. Iturria-Medina et al. Nature Communications
- Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins
- (2016) N Voyle et al. Translational Psychiatry
- Sharpening Precision Medicine by a Thorough Interrogation of Metabolic Individuality
- (2016) Kirk Beebe et al. Computational and Structural Biotechnology Journal
- Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia
- (2016) Adriana Cristofano et al. PLoS One
- Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer’s disease subjects
- (2015) Paul L. Wood et al. ACTA NEUROPSYCHIATRICA
- Increase the accessibility and scale of targeted metabolomics: Construction of a human urinary metabolome-wide multiple reaction monitoring library using directly-coupled reversed-phase and hydrophilic interaction chromatography
- (2015) Zhixiang Yan et al. ANALYTICA CHIMICA ACTA
- Effects of pre-analytical processes on blood samples used in metabolomics studies
- (2015) Peiyuan Yin et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Glycosphingolipids and cell death: one aim, many ways
- (2015) Carmen Garcia-Ruiz et al. APOPTOSIS
- Deciphering metabolic abnormalities associated with Alzheimer's disease in the APP/PS1 mouse model using integrated metabolomic approaches
- (2015) Raúl González-Domínguez et al. BIOCHIMIE
- Metabolomics reveals significant impairments in the immune system of the APP/PS1 transgenic mice of Alzheimer's disease
- (2015) Raúl González-Domínguez et al. ELECTROPHORESIS
- High throughput multiorgan metabolomics in the APP/PS1 mouse model of Alzheimer's disease
- (2015) Raúl González-Domínguez et al. ELECTROPHORESIS
- Blood metabolite markers of cognitive performance and brain function in aging
- (2015) Brittany N Simpson et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cerebral Hypoperfusion and Hypometabolism Detected by Arterial Spin Labeling MRI and FDG-PET in Early-Onset Alzheimer's Disease
- (2015) Sebastien Verclytte et al. JOURNAL OF NEUROIMAGING
- Application of metabolomics based on direct mass spectrometry analysis for the elucidation of altered metabolic pathways in serum from the APP/PS1 transgenic model of Alzheimer's disease
- (2015) Raúl González-Domínguez et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Metabolomic screening of regional brain alterations in the APP/PS1 transgenic model of Alzheimer's disease by direct infusion mass spectrometry
- (2015) Raúl González-Domínguez et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Metabolite profiling for the identification of altered metabolic pathways in Alzheimer's disease
- (2015) Raúl González-Domínguez et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Gender-specific pathway differences in the human serum metabolome
- (2015) Jan Krumsiek et al. Metabolomics
- Metabolomic investigation of systemic manifestations associated with Alzheimer's disease in the APP/PS1 transgenic mouse model
- (2015) Raúl González-Domínguez et al. Molecular BioSystems
- Acylcarnitines—old actors auditioning for new roles in metabolic physiology
- (2015) Colin S. McCoin et al. Nature Reviews Endocrinology
- Ceramides in Alzheimer’s Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and AβAccumulation
- (2015) Maja Jazvinšćak Jembrek et al. Oxidative Medicine and Cellular Longevity
- Application of a novel metabolomic approach based on atmospheric pressure photoionization mass spectrometry using flow injection analysis for the study of Alzheimer׳s disease
- (2015) Raúl González-Domínguez et al. TALANTA
- Ceramides – Lipotoxic Inducers of Metabolic Disorders
- (2015) Bhagirath Chaurasia et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer’s disease subjects
- (2015) Paul L. Wood et al. ACTA NEUROPSYCHIATRICA
- Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease
- (2015) P Proitsi et al. Translational Psychiatry
- Untargeted Metabolomic Analysis of Human Plasma Indicates Differentially Affected Polyamine and L-Arginine Metabolism in Mild Cognitive Impairment Subjects Converting to Alzheimer’s Disease
- (2015) Stewart F. Graham et al. PLoS One
- A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease
- (2014) Frank Jessen et al. Alzheimers & Dementia
- Using direct infusion mass spectrometry for serum metabolomics in Alzheimer’s disease
- (2014) R. González-Domínguez et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry
- (2014) Raúl González-Domínguez et al. ELECTROPHORESIS
- Quantification of the Brain Proteome in Alzheimer’s Disease Using Multiplexed Mass Spectrometry
- (2014) Sravani Musunuri et al. JOURNAL OF PROTEOME RESEARCH
- Combination of metabolomic and phospholipid-profiling approaches for the study of Alzheimer's disease
- (2014) Raúl González-Domínguez et al. Journal of Proteomics
- An atlas of genetic influences on human blood metabolites
- (2014) So-Youn Shin et al. NATURE GENETICS
- Plasma phospholipids identify antecedent memory impairment in older adults
- (2014) Mark Mapstone et al. NATURE MEDICINE
- Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease
- (2014) Zhentao Zhang et al. NATURE MEDICINE
- Ceramides and sphingomyelinases in senile plaques
- (2014) Maï Panchal et al. NEUROBIOLOGY OF DISEASE
- Heme oxygenase-1 protects against Alzheimer’s amyloid-β1-42-induced toxicity via carbon monoxide production
- (2014) N Hettiarachchi et al. Cell Death & Disease
- Blood biomarkers for Alzheimer’s disease
- (2014) Simon Lovestone Genome Medicine
- Lipidomics of familial longevity
- (2013) Vanessa Gonzalez-Covarrubias et al. AGING CELL
- Recent advances in the application of metabolomics to Alzheimer's Disease
- (2013) Eugenia Trushina et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- New Advances in Separation Science for Metabolomics: Resolving Chemical Diversity in a Post-Genomic Era
- (2013) Naomi L. Kuehnbaum et al. CHEMICAL REVIEWS
- Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
- (2013) Clifford R Jack et al. LANCET NEUROLOGY
- Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer’s disease
- (2013) Yoko Tajima et al. Lipids in Health and Disease
- NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations
- (2013) Abdul-Hamid M. Emwas et al. Metabolomics
- Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database
- (2013) Zheng-Jiang Zhu et al. Nature Protocols
- Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease
- (2013) Luke Whiley et al. NEUROBIOLOGY OF AGING
- Deficiency of Asparagine Synthetase Causes Congenital Microcephaly and a Progressive Form of Encephalopathy
- (2013) Elizabeth K. Ruzzo et al. NEURON
- Biomarker Modeling of Alzheimer’s Disease
- (2013) Clifford R. Jack et al. NEURON
- Identification of Altered Metabolic Pathways in Plasma and CSF in Mild Cognitive Impairment and Alzheimer’s Disease Using Metabolomics
- (2013) Eugenia Trushina et al. PLoS One
- Human serum metabolic profiles are age dependent
- (2012) Zhonghao Yu et al. AGING CELL
- Acylcarnitines
- (2012) Marieke G. Schooneman et al. DIABETES
- Metabolomics: the apogee of the omics trilogy
- (2012) Gary J. Patti et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Serum ceramides increase the risk of Alzheimer disease: The Women's Health and Aging Study II
- (2012) M. M. Mielke et al. NEUROLOGY
- Comparative Lipidomic Analysis of Mouse and Human Brain with Alzheimer Disease
- (2011) Robin B. Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mass spectrometry-based holistic analytical approaches for metabolite profiling in systems biology studies
- (2011) Georgios Theodoridis et al. MASS SPECTROMETRY REVIEWS
- Hydroxylated and non-hydroxylated sulfatide are distinctly distributed in the human cerebral cortex
- (2011) D. Yuki et al. NEUROSCIENCE
- Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics
- (2011) Xianlin Han et al. PLoS One
- Oxidative metabolism of dehydroepiandrosterone (DHEA) and biologically active oxygenated metabolites of DHEA and epiandrosterone (EpiA) – Recent reports
- (2011) Laïla El Kihel STEROIDS
- Direct-injection mass spectrometry adds the time dimension to (B)VOC analysis
- (2011) Franco Biasioli et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers
- (2011) Kirstin Mittelstrass et al. PLoS Genetics
- Metabolome in progression to Alzheimer's disease
- (2011) M Orešič et al. Translational Psychiatry
- Kynurenine and its metabolites in Alzheimer's disease patients
- (2010) E Gulaj et al. Advances in Medical Sciences
- Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss
- (2010) Michelle M. Mielke et al. Alzheimers & Dementia
- Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study
- (2010) Robert K McNamara et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- The Role of the Lipid Bilayer in Tau Aggregation
- (2010) Shana Elbaum-Garfinkle et al. BIOPHYSICAL JOURNAL
- Plasma metabolic profiling of Alzheimer's disease by liquid chromatography/mass spectrometry
- (2010) Nai-jing Li et al. CLINICAL BIOCHEMISTRY
- Sphingolipids and insulin resistance: the five Ws
- (2010) Scott A Summers CURRENT OPINION IN LIPIDOLOGY
- Lipid map of the mammalian cell
- (2010) G. van Meer et al. JOURNAL OF CELL SCIENCE
- Blood sphingolipidomics in healthy humans: impact of sample collection methodology
- (2010) Samar M. Hammad et al. JOURNAL OF LIPID RESEARCH
- Lipidomics reveals a remarkable diversity of lipids in human plasma,
- (2010) Oswald Quehenberger et al. JOURNAL OF LIPID RESEARCH
- Heme oxygenase-1 in Alzheimer disease: a tribute to Moussa Youdim
- (2010) Hyman M. Schipper JOURNAL OF NEURAL TRANSMISSION
- Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity
- (2010) Stephanie J. Mihalik et al. Obesity
- Presenilin 1 modifies lipid raft composition of neuronal membranes
- (2009) Gunter P. Eckert et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Acylcarnitines: Role in brain
- (2009) Lauren L. Jones et al. PROGRESS IN LIPID RESEARCH
- High-Resolution Mass Spectrometers
- (2008) Alan G. Marshall et al. Annual Review of Analytical Chemistry
- Principles of bioactive lipid signalling: lessons from sphingolipids
- (2008) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now