Heme oxygenase-1 protects against Alzheimer’s amyloid-β1-42-induced toxicity via carbon monoxide production

The Prion Protein Modulates A-type K+Currents Mediated by Kv4.2 Complexes through Dipeptidyl Aminopeptidase-like Protein 6

(2013) Robert C. C. Mercer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1

(2013) Jo V. Rushworth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Aβ Oligomers through Tau Phosphorylation

(2013) Georges Mairet-Coello et al.   NEURON

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

(2013) Andrew J. Nicoll et al.   Nature Communications

Carbon Monoxide Mediates the Anti-apoptotic Effects of Heme Oxygenase-1 in Medulloblastoma DAOY Cells via K+Channel Inhibition

(2012) Moza M. A. Al-Owais et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unregulated brain iron deposition in transgenic mice over-expressingHMOX1in the astrocytic compartment

(2012) Wei Song et al.   JOURNAL OF NEUROCHEMISTRY

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

JNK3 Perpetuates Metabolic Stress Induced by Aβ Peptides

(2012) Sung Ok Yoon et al.   NEURON

Prion protein facilitates uptake of zinc into neuronal cells

(2012) Nicole T. Watt et al.   Nature Communications

AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure

(2011) Claire Thornton et al.   BIOCHEMICAL JOURNAL

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

(2011) Ulrike K Resenberger et al.   EMBO JOURNAL

Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1

(2011) Mark L. Dallas et al.   FASEB JOURNAL

Interaction between Human Prion Protein and Amyloid-β (Aβ) Oligomers

(2010) Shugui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Suppression of Glial HO-1 Activitiy as a Potential Neurotherapeutic Intervention in AD

(2009) Hyman Schipper et al.   Current Alzheimer Research

Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement

(2009) Hyman M. Schipper et al.   JOURNAL OF NEUROCHEMISTRY

Hypoxia-inducible factor 1: a new hope to counteract neurodegeneration?

(2009) Sónia C. Correia et al.   JOURNAL OF NEUROCHEMISTRY

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Low Doses of Carbon Monoxide Protect Against Experimental Focal Brain Ischemia

(2009) Emil Zeynalov et al.   NEUROTOXICITY RESEARCH

Inhibitors of the heme oxygenase – carbon monoxide system: on the doorstep of the clinic?

(2008) Robert T. Kinobe et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY