NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations
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Title
NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations
Authors
Keywords
Diagnosis, Prognosis, NMR spectroscopy, Metabolomics, Metabonomics, Biomarkers, Metabolic fingerprinting
Journal
Metabolomics
Volume 9, Issue 5, Pages 1048-1072
Publisher
Springer Nature
Online
2013-04-02
DOI
10.1007/s11306-013-0524-y
References
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Note: Only part of the references are listed.- Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database
- (2013) Zheng-Jiang Zhu et al. Nature Protocols
- NMR and pattern recognition methods in metabolomics: From data acquisition to biomarker discovery: A review
- (2012) Agnieszka Smolinska et al. ANALYTICA CHIMICA ACTA
- Utilities for quantifying separation in PCA/PLS-DA scores plots
- (2012) Bradley Worley et al. ANALYTICAL BIOCHEMISTRY
- Structural Characterization of Plasma Metabolites Detected via LC-Electrochemical Coulometric Array Using LC-UV Fractionation, MS, and NMR
- (2012) Susan S. Bird et al. ANALYTICAL CHEMISTRY
- Investigation of the Human Brain Metabolome to Identify Potential Markers for Early Diagnosis and Therapeutic Targets of Alzheimer’s Disease
- (2012) Stewart F. Graham et al. ANALYTICAL CHEMISTRY
- Metabolomics and its potential in drug development
- (2012) Diren Beyoğlu et al. BIOCHEMICAL PHARMACOLOGY
- NMR-based metabolomics study of canine bladder cancer
- (2012) Jian Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Non-negative principal component analysis for NMR-based metabolomic data analysis
- (2012) Lingli Deng et al. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
- Exploring High-resolution Magic Angle Spinning (HR-MAS) NMR Spectroscopy for Metabonomic Analysis of Apples
- (2012) Martina Vermathen et al. CHIMIA
- Identification of Serum Proton NMR Metabolomic Fingerprints Associated with Hepatocellular Carcinoma in Patients with Alcoholic Cirrhosis
- (2012) P. Nahon et al. CLINICAL CANCER RESEARCH
- Metabolomics and ischaemic heart disease
- (2012) Aliki A. Rasmiena et al. CLINICAL SCIENCE
- Host Responses in Malaria Disease Evaluated Through Nuclear Magnetic Resonance–Based Metabonomics
- (2012) Haripalsingh M. Sonawat et al. CLINICS IN LABORATORY MEDICINE
- Application of NMR Metabolomics to Search for Human Disease Biomarkers
- (2012) Teklab Gebregiworgis et al. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
- A Pilot Metabolic Profiling Study in Serum of Patients with Chronic Kidney Disease Based on1H-NMR-Spectroscopy
- (2012) Suwen Qi et al. CTS-Clinical and Translational Science
- Review Metabolomics: A New Approach to Drug Delivery in Perinatology
- (2012) L. Atzori et al. CURRENT MEDICINAL CHEMISTRY
- Serum Metabolic Profiling in Inflammatory Bowel Disease
- (2012) Horace R. T. Williams et al. DIGESTIVE DISEASES AND SCIENCES
- Comparison of the metabolic profiling of hepatitis B virus-infected cirrhosis and alcoholic cirrhosis patients by using 1H NMR-based metabonomics
- (2012) Suwen Qi et al. HEPATOLOGY RESEARCH
- Comprehensive analysis of commercial willow bark extracts by new technology platform: Combined use of metabolomics, high-performance liquid chromatography–solid-phase extraction–nuclear magnetic resonance spectroscopy and high-resolution radical scavenging assay
- (2012) Sara Agnolet et al. JOURNAL OF CHROMATOGRAPHY A
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- (2012) Muireann Coen et al. JOURNAL OF PROTEOME RESEARCH
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- (2012) Hua-Lin Cai et al. JOURNAL OF PROTEOME RESEARCH
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- (2012) Beatriz Jiménez et al. JOURNAL OF PROTEOME RESEARCH
- Holistic metabonomic profiling of urine affords potential early diagnosis for bladder and kidney cancers
- (2012) Zhenzhen Huang et al. Metabolomics
- NMR-based metabolomic study of type 1 diabetes
- (2012) Nicola Culeddu et al. Metabolomics
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- (2012) Neil MacKinnon et al. Metabolomics
- Magic angle spinning NMR spectroscopic metabolic profiling of gall bladder tissues for differentiating malignant from benign disease
- (2012) Santosh Kumar Bharti et al. Metabolomics
- 1H NMR-based metabolic profiling of urinary tract infection: combining multiple statistical models and clinical data
- (2012) Ekaterina Nevedomskaya et al. Metabolomics
- MetaboLights: towards a new COSMOS of metabolomics data management
- (2012) Christoph Steinbeck et al. Metabolomics
- Dupuytren's disease metabolite analyses reveals alterations following initial short-term fibroblast culturing
- (2012) Samrina Rehman et al. Molecular BioSystems
- Exploration of serum metabolomic profiles and outcomes in women with metastatic breast cancer: A pilot study
- (2012) Leonardo Tenori et al. Molecular Oncology
- MetaboLights—an open-access general-purpose repository for metabolomics studies and associated meta-data
- (2012) Kenneth Haug et al. NUCLEIC ACIDS RESEARCH
- Metabolic Fingerprinting of Tussilago farfara L. Using 1H-NMR Spectroscopy and Multivariate Data Analysis
- (2012) Hai-Juan Zhi et al. PHYTOCHEMICAL ANALYSIS
- Metabolic Changes in Urine during and after Pregnancy in a Large, Multiethnic Population-Based Cohort Study of Gestational Diabetes
- (2012) Daniel Sachse et al. PLoS One
- Surface-activated chemical ionization-electrospray mass spectrometry in the analysis of urinary thiodiglycolic acid
- (2012) Giovanni Puccio et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Metabolomics: a novel approach to identify potential diagnostic biomarkers and pathogenesis in Alzheimer’s disease
- (2012) Xu-Hua Xu et al. Neuroscience Bulletin
- Potential Effect of Diaper and Cotton Ball Contamination on NMR- and LC/MS-Based Metabonomics Studies of Urine from Newborn Babies
- (2011) Aaron M. Goodpaster et al. ANALYTICAL CHEMISTRY
- 1H NMR based metabolomics of CSF and blood serum: A metabolic profile for a transgenic rat model of Huntington disease
- (2011) Kim A. Verwaest et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2011) He Wen et al. Biomolecules & Therapeutics
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- (2011) A. Backshall et al. CLINICAL CANCER RESEARCH
- A comparison of the metabolic profile on intact tissue and extracts of muscle and liver of juvenile Atlantic salmon (Salmo salar L.) – Application to a short feeding study
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- (2011) Z.A. Al-Talla et al. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
- The application of micro-coil NMR probe technology to metabolomics of urine and serum
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- (2011) Crina I. A. Balog et al. Molecular BioSystems
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- The Human Serum Metabolome
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- Recent and potential developments in the analysis of urine: A review
- (2010) D. Ryan et al. ANALYTICA CHIMICA ACTA
- Quantitative Analysis of Blood Plasma Metabolites Using Isotope Enhanced NMR Methods
- (2010) G. A. Nagana Gowda et al. ANALYTICAL CHEMISTRY
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- Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
- (2010) Warwick B. Dunn et al. CHEMICAL SOCIETY REVIEWS
- Kinetics from Indirectly Detected Hyperpolarized NMR Spectroscopy by Using Spatially Selective Coherence Transfers
- (2010) Talia Harris et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2010) Martin Feller et al. CLINICAL INFECTIOUS DISEASES
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- Predicting idiopathic toxicity of cisplatin by a pharmacometabonomic approach
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- (2010) Angika Basant et al. MALARIA JOURNAL
- Standardization of factors that influence human urine metabolomics
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- (2010) M K Chan et al. MOLECULAR PSYCHIATRY
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- (2010) Prashant R. Nambiar et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Pharmacometabonomics as an effector for personalized medicine
- (2010) Jeremy K Nicholson et al. PHARMACOGENOMICS
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- (2010) Christian Ludwig et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Enhancement of Plant Metabolite Fingerprinting by Machine Learning
- (2010) I. M. Scott et al. PLANT PHYSIOLOGY
- 1H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis
- (2010) Hélène Blasco et al. PLoS One
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- (2009) Eduard Y. Chekmenev et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Schizophrenia
- (2009) Jim van Os et al. LANCET
- Comparison of squamous cell carcinoma and adenocarcinoma of the lung by metabolomic analysis of tissue–serum pairs
- (2009) K.W. Jordan et al. LUNG CANCER
- Standard operating procedure for metabonomics studies of blood serum and plasma samples using a 1H-NMR micro-flow probe
- (2009) Dinesh K. Sukumaran et al. MAGNETIC RESONANCE IN CHEMISTRY
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- (2009) Zhong-ying Lin et al. NMR IN BIOMEDICINE
- Two-dimensional J-resolved NMR spectroscopy: review of a key methodology in the metabolomics toolbox
- (2009) Christian Ludwig et al. PHYTOCHEMICAL ANALYSIS
- Simple data-reduction method for high-resolution LC–MS data in metabolomics
- (2009) RA Scheltema et al. Bioanalysis
- Integrating post-genomic approaches as a strategy to advance our understanding of health and disease
- (2009) Jing Tang et al. Genome Medicine
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- (2008) Shucha Zhang et al. ANALYTICAL BIOCHEMISTRY
- Optimized metabolite extraction from blood serum for 1H nuclear magnetic resonance spectroscopy
- (2008) Stefano Tiziani et al. ANALYTICAL BIOCHEMISTRY
- Global Metabolic Profiling ofEscherichia coliCultures: an Evaluation of Methods for Quenching and Extraction of Intracellular Metabolites
- (2008) Catherine L. Winder et al. ANALYTICAL CHEMISTRY
- Determinants for Optimal Enhancement in Ex Situ DNP Experiments
- (2008) A.-H. Emwas et al. APPLIED MAGNETIC RESONANCE
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- (2008) R. H Barton et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
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- (2008) R. J. O. Torgrip et al. Metabolomics
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- (2008) Simone J. Rochfort et al. Metabolomics
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- (2007) Nikolaos G. Psihogios et al. NMR IN BIOMEDICINE
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