Nuclear Receptors Linking Metabolism, Inflammation, and Fibrosis in Nonalcoholic Fatty Liver Disease
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Title
Nuclear Receptors Linking Metabolism, Inflammation, and Fibrosis in Nonalcoholic Fatty Liver Disease
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 5, Pages 2668
Publisher
MDPI AG
Online
2022-03-01
DOI
10.3390/ijms23052668
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Note: Only part of the references are listed.- Interleukin-1 as Innate Mediator of T Cell Immunity
- (2021) Bram Van Den Eeckhout et al. Frontiers in Immunology
- Role of Oxidative Stress in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: Implications for Prevention and Therapy
- (2021) Johanna C. Arroyave-Ospina et al. Antioxidants
- The FALCON program: Two phase 2b randomized, double-blind, placebo-controlled studies to assess the efficacy and safety of pegbelfermin in the treatment of patients with nonalcoholic steatohepatitis and bridging fibrosis or compensated cirrhosis
- (2021) Manal F. Abdelmalek et al. Contemporary Clinical Trials
- Inflammatory Mechanisms Underlying Nonalcoholic Steatohepatitis and the Transition to Hepatocellular Carcinoma
- (2021) Moritz Peiseler et al. Cancers
- Transcriptional Regulation of Metabolic Pathways via Lipid-Sensing Nuclear Receptors
- (2021) Marica Cariello et al. Cellular and Molecular Gastroenterology and Hepatology
- Necroptosis, pyroptosis and apoptosis: an intricate game of cell death
- (2021) Damien Bertheloot et al. Cellular & Molecular Immunology
- Saroglitazar, a PPAR‐α/γ Agonist, for Treatment of Nonalcoholic Fatty Liver Disease: A Randomized Controlled Double‐Blind Phase 2 Trial
- (2021) Samer Gawrieh et al. HEPATOLOGY
- Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide
- (2021) Dakota R. Kamm et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepatoprotective effect of Qushihuayu formula on non-alcoholic steatohepatitis induced by MCD diet in rat
- (2021) Qingping Lan et al. Chinese Medicine
- Tiliroside Ameliorates Ulcerative Colitis by Restoring the M1/M2 Macrophage Balance via the HIF-1α/glycolysis Pathway
- (2021) Hongda Zhuang et al. Frontiers in Immunology
- Emerging functions of the nuclear receptor LRH-1 in liver physiology and pathology
- (2021) Yu Sun et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A subset of Kupffer cells regulates metabolism through the expression of CD36
- (2021) Camille Blériot et al. IMMUNITY
- Roles of nuclear receptors in hepatic stellate cells
- (2021) Shiyun Pu et al. Expert Review of Gastroenterology & Hepatology
- Novel therapeutic targets for cholestatic and fatty liver disease
- (2021) Michael Trauner et al. GUT
- Aramchol in patients with nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled phase 2b trial
- (2021) V. Ratziu et al. NATURE MEDICINE
- Advancing the global public health agenda for NAFLD: a consensus statement
- (2021) Jeffrey V. Lazarus et al. Nature Reviews Gastroenterology & Hepatology
- A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH
- (2021) Sven M. Francque et al. NEW ENGLAND JOURNAL OF MEDICINE
- Caspases in Cell Death, Inflammation, and Gasdermin-Induced Pyroptosis
- (2020) Sannula Kesavardhana et al. Annual Review of Immunology
- Fibroblast growth factor (FGF)-21 based therapies: A magic bullet for nonalcoholic fatty liver disease (NAFLD)?
- (2020) Michael Ritchie et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Cilofexor, a Nonsteroidal FXR Agonist, in Non‐Cirrhotic Patients with Nonalcoholic Steatohepatitis: A Phase 2 Randomized Controlled Trial
- (2020) Keyur Patel et al. HEPATOLOGY
- New drugs for non‐alcoholic steatohepatitis
- (2020) Ana‐Carolina Cardoso et al. LIVER INTERNATIONAL
- Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease
- (2020) Ze Chen et al. FREE RADICAL BIOLOGY AND MEDICINE
- PPARs as Metabolic Regulators in the Liver: Lessons from Liver-Specific PPAR-Null Mice
- (2020) Yaping Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages
- (2020) Sander Lefere et al. JOURNAL OF HEPATOLOGY
- Lytic cell death in metabolic liver disease
- (2020) Jérémie Gautheron et al. JOURNAL OF HEPATOLOGY
- Cholesterol Induces Nrf-2- and HIF-1α-Dependent Hepatocyte Proliferation and Liver Regeneration to Ameliorate Bile Acid Toxicity in Mouse Models of NASH and Fibrosis
- (2020) Yula Kaminsky-Kolesnikov et al. Oxidative Medicine and Cellular Longevity
- TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice
- (2020) Franziska Wandrer et al. Cell Death & Disease
- Involvement of Nucleotide-Binding Oligomerization Domain-Like Receptor Family Pyrin Domain Containing 3 Inflammasome in the Pathogenesis of Liver Diseases
- (2020) Congjian Shi et al. Frontiers in Cell and Developmental Biology
- Current and emerging pharmacotherapeutic interventions for the treatment of liver fibrosis
- (2020) Joeri Lambrecht et al. EXPERT OPINION ON PHARMACOTHERAPY
- Efficacy and Safety of Aldafermin, an Engineered FGF19 Analog, in a Randomized, Double-Blind, Placebo-Controlled Trial of Patients With Nonalcoholic Steatohepatitis
- (2020) Stephen A. Harrison et al. GASTROENTEROLOGY
- Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis
- (2020) Sophie Tran et al. IMMUNITY
- Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
- (2020) Susanne Gaul et al. JOURNAL OF HEPATOLOGY
- Biological mechanisms and therapeutic relevance of the gasdermin family
- (2020) Shiyu Xia MOLECULAR ASPECTS OF MEDICINE
- PPARγ-mediated microglial activation phenotype is involved in depressive-like behaviors and neuroinflammation in stressed C57BL/6J and ob/ob mice
- (2020) Xiaqing Qin et al. PSYCHONEUROENDOCRINOLOGY
- The NLRP3 Inflammasome in Alcoholic and Nonalcoholic Steatohepatitis
- (2020) Jana Knorr et al. SEMINARS IN LIVER DISEASE
- The PPAR α/γ Agonist Saroglitazar Improves Insulin Resistance and Steatohepatitis in a Diet Induced Animal Model of Nonalcoholic Fatty Liver Disease
- (2020) Divya P. Kumar et al. Scientific Reports
- Trained Immunity
- (2020) Helin Tercan et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver
- (2020) Anneleen Remmerie et al. IMMUNITY
- Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors
- (2020) Sven Francque et al. Nature Reviews Gastroenterology & Hepatology
- RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages
- (2020) Liang Tao et al. CELL DEATH AND DIFFERENTIATION
- Gut microbiome, liver immunology, and liver diseases
- (2020) Rui Wang et al. Cellular & Molecular Immunology
- RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease
- (2020) Marta B Afonso et al. GUT
- Cell Death in Liver Diseases: A Review
- (2020) Layla Shojaie et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention
- (2020) Daniel Q. Huang et al. Nature Reviews Gastroenterology & Hepatology
- Additive Effects of Omega-3 Fatty Acids and Thiazolidinediones in Mice Fed a High-Fat Diet: Triacylglycerol/Fatty Acid Cycling in Adipose Tissue
- (2020) Kristina Bardova et al. Nutrients
- Nuclear hormone and peptide hormone therapeutics for NAFLD and NASH
- (2020) Brian Finan et al. Molecular Metabolism
- Nuclear receptors and transcriptional regulation in non-alcoholic fatty liver disease
- (2020) Yang Xiao et al. Molecular Metabolism
- Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model
- (2019) Ziv Erlich et al. NATURE IMMUNOLOGY
- NGM 282 Improves Liver Fibrosis and Histology in 12 Weeks in Patients with Nonalcoholic Steatohepatitis
- (2019) Stephen A. Harrison et al. HEPATOLOGY
- Biological mechanisms and related natural modulators of liver X receptor in nonalcoholic fatty liver disease
- (2019) Mingzhu Ni et al. BIOMEDICINE & PHARMACOTHERAPY
- Cell death: a review of the major forms of apoptosis, necrosis and autophagy
- (2019) Mark S D’Arcy CELL BIOLOGY INTERNATIONAL
- From NASH to HCC: current concepts and future challenges
- (2019) Quentin M. Anstee et al. Nature Reviews Gastroenterology & Hepatology
- TNFα-Mediated Necroptosis Aggravates Ischemia-Reperfusion Injury in the Fatty Liver by Regulating the Inflammatory Response
- (2019) Faji Yang et al. Oxidative Medicine and Cellular Longevity
- Report on the AASLD/EASL joint workshop on clinical trial endpoints in NAFLD
- (2019) Mary E. Rinella et al. JOURNAL OF HEPATOLOGY
- CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients
- (2019) Paul J. Pockros et al. LIVER INTERNATIONAL
- DAMPs, PAMPs, and LAMPs in Immunity and Sterile Inflammation
- (2019) Joel Zindel et al. Annual Review of Pathology-Mechanisms of Disease
- Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis
- (2019) Xiaoli Sun et al. Cell Metabolism
- Insulin sensitizer MSDC-0602K in non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled phase IIb study
- (2019) Stephen A. Harrison et al. JOURNAL OF HEPATOLOGY
- Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease
- (2019) Amine Majdi et al. JOURNAL OF HEPATOLOGY
- The potential role of necroptosis in inflammaging and aging
- (2019) Gordon H. Royce et al. GeroScience
- New drugs for NAFLD: lessons from basic models to the clinic
- (2019) Katharina C. Reimer et al. Hepatology International
- Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial
- (2019) Zobair M Younossi et al. LANCET
- Clinical and metabolic effects associated with weight changes and obeticholic acid in non-alcoholic steatohepatitis
- (2018) B. Hameed et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease
- (2018) Juan Pablo Arab et al. Annual Review of Pathology-Mechanisms of Disease
- Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications
- (2018) Gloria Alvarez-Sola et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Non-alcoholic Steatohepatitis is the Fastest Growing Cause of Hepatocellular Carcinoma in Liver Transplant Candidates
- (2018) Zobair Younossi et al. Clinical Gastroenterology and Hepatology
- Dose-dependent effects of peroxisome proliferator-activated receptors β/δ agonist on systemic inflammation after haemorrhagic shock
- (2018) Luxu Yin et al. CYTOKINE
- Saroglitazar reduces obesity and associated inflammatory consequences in murine adipose tissue
- (2018) Durgesh Kumar et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Non-alcoholic steatohepatitis pathogenesis: sublethal hepatocyte injury as a driver of liver inflammation
- (2018) Samar H Ibrahim et al. GUT
- Cyclophilin D deficiency attenuates mitochondrial perturbation and ameliorates hepatic steatosis
- (2018) Xiaolei Wang et al. HEPATOLOGY
- Pivotal Roles of Peroxisome Proliferator-Activated Receptors (PPARs) and Their Signal Cascade for Cellular and Whole-Body Energy Homeostasis
- (2018) Shreekrishna Lamichane et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hypertension, diabetes, atherosclerosis and NASH: Cause or consequence?
- (2018) Amedeo Lonardo et al. JOURNAL OF HEPATOLOGY
- Mechanisms of NAFLD development and therapeutic strategies
- (2018) Scott L. Friedman et al. NATURE MEDICINE
- Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis
- (2018) Bin Guo et al. NATURE MEDICINE
- Triggering and resolution of inflammation in NASH
- (2018) Susanne Schuster et al. Nature Reviews Gastroenterology & Hepatology
- Innate immune cells in the adipose tissue
- (2018) Kyoung-Jin Chung et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease
- (2018) Mohammad Zarei et al. Molecular Metabolism
- Beyond the Foam Cell: The Role of LXRs in Preventing Atherogenesis
- (2018) Adil Rasheed et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Apoptosis and necroptosis in the liver: a matter of life and death
- (2018) Robert F. Schwabe et al. Nature Reviews Gastroenterology & Hepatology
- An update on the recent advances in antifibrotic therapy
- (2018) Frank Tacke et al. Expert Review of Gastroenterology & Hepatology
- Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
- (2018) Marcus Grohmann et al. CELL
- Modulation of Insulin Resistance in NAFLD
- (2018) Reenam Khan et al. HEPATOLOGY
- Danger-Associated Molecular Patterns (DAMPs): Molecular Triggers for Sterile Inflammation in the Liver
- (2018) Sabine Mihm INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial
- (2018) Arun Sanyal et al. LANCET
- The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
- (2018) Konstantin Kazankov et al. Nature Reviews Gastroenterology & Hepatology
- Metabolic aspects in NAFLD, NASH and hepatocellular carcinoma: the role of PGC1 coactivators
- (2018) Elena Piccinin et al. Nature Reviews Gastroenterology & Hepatology
- Regulation of Hepatic Inflammation via Macrophage Cell Death
- (2018) Zhuan Li et al. SEMINARS IN LIVER DISEASE
- Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease
- (2017) Oscar Chávez-Talavera et al. GASTROENTEROLOGY
- Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration
- (2017) Gloria Alvarez-Sola et al. GUT
- Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease
- (2017) Chris Estes et al. HEPATOLOGY
- Overview of the IL-1 family in innate inflammation and acquired immunity
- (2017) Charles A. Dinarello IMMUNOLOGICAL REVIEWS
- Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease
- (2017) Sokrates Stein et al. JOURNAL OF CLINICAL INVESTIGATION
- Current and future pharmacological therapies for NAFLD/NASH
- (2017) Yoshio Sumida et al. JOURNAL OF GASTROENTEROLOGY
- NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
- (2017) Auvro R. Mridha et al. JOURNAL OF HEPATOLOGY
- Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization
- (2017) Eleni Vergadi et al. JOURNAL OF IMMUNOLOGY
- Dual PPARα/γ agonist saroglitazar improves liver histopathology and biochemistry in experimental NASH models
- (2017) Mukul R. Jain et al. LIVER INTERNATIONAL
- The role of bile acids in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
- (2017) Monica D. Chow et al. MOLECULAR ASPECTS OF MEDICINE
- Inflammation, metaflammation and immunometabolic disorders
- (2017) Gökhan S. Hotamisligil NATURE
- Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
- (2017) Zobair Younossi et al. Nature Reviews Gastroenterology & Hepatology
- Targeting nuclear receptors for the treatment of fatty liver disease
- (2017) Naoki Tanaka et al. PHARMACOLOGY & THERAPEUTICS
- Macrophages in Nonalcoholic Fatty Liver Disease: A Role Model of Pathogenic Immunometabolism
- (2017) Oliver Krenkel et al. SEMINARS IN LIVER DISEASE
- Macrophage Immunometabolism: Where Are We (Going)?
- (2017) Jan Van den Bossche et al. TRENDS IN IMMUNOLOGY
- Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex
- (2017) So Yeon Kim et al. Nature Communications
- Dynamic plasticity of macrophage functions in diseased liver
- (2017) Thomas Ritz et al. CELLULAR IMMUNOLOGY
- The Role of Nuclear Receptors in the Pathophysiology, Natural Course, and Drug Treatment of NAFLD in Humans
- (2016) Stefano Ballestri et al. ADVANCES IN THERAPY
- Nuclear receptors and nonalcoholic fatty liver disease 1 1This article is part of a Special Issue entitled: Xenobiotic nuclear receptors: New Tricks for An Old Dog, edited by Dr. Wen Xie.
- (2016) Matthew C. Cave et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal
- (2016) Evanna L. Mills et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening
- (2016) Vlad Ratziu et al. GASTROENTEROLOGY
- Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
- (2016) Alexandra Montagner et al. GUT
- Microbiota-induced obesity requires farnesoid X receptor
- (2016) Ava Parséus et al. GUT
- Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives
- (2016) Juan P. Arab et al. HEPATOLOGY
- The role of macrophages in obesity-driven chronic liver disease
- (2016) Lindsey Devisscher et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Fatty acid oxidation in macrophage polarization
- (2016) Mitsunori Nomura et al. NATURE IMMUNOLOGY
- PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD
- (2016) Barbara Gross et al. Nature Reviews Endocrinology
- Nuclear Receptor Modulation for the Treatment of Nonalcoholic Fatty Liver Disease
- (2016) Claudia Fuchs et al. SEMINARS IN LIVER DISEASE
- Genomics of human fatty liver disease reveal mechanistically linked lipid droplet–associated gene regulations in bland steatosis and nonalcoholic steatohepatitis
- (2016) Nishika Sahini et al. Translational Research
- The Role of Cholesterol in the Pathogenesis of NASH
- (2016) George N. Ioannou TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
- (2016) Charlotte L. Scott et al. Nature Communications
- Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis
- (2015) Marta B. Afonso et al. CLINICAL SCIENCE
- Bile Acids as Hormones: The FXR-FGF15/19 Pathway
- (2015) Steven A. Kliewer et al. DIGESTIVE DISEASES
- Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease
- (2015) Paul Angulo et al. GASTROENTEROLOGY
- Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up
- (2015) Mattias Ekstedt et al. HEPATOLOGY
- PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis
- (2015) Sven Francque et al. JOURNAL OF HEPATOLOGY
- The PPAR-γ antagonist GW9662 elicits differentiation of M2c-like cells and upregulation of the MerTK/Gas6 axis: a key role for PPAR-γ in human macrophage polarization
- (2015) Gaetano Zizzo et al. Journal of Inflammation-London
- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
- (2015) Brent A Neuschwander-Tetri et al. LANCET
- Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
- (2015) Sungsoon Fang et al. NATURE MEDICINE
- Inflammasome activation and function in liver disease
- (2015) Gyongyi Szabo et al. Nature Reviews Gastroenterology & Hepatology
- Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction
- (2015) Changtao Jiang et al. Nature Communications
- A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver
- (2015) Miyuki Suzawa et al. eLife
- LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling
- (2015) Ayaka Ito et al. eLife
- Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration
- (2015) Guodong Li et al. Acta Pharmaceutica Sinica B
- Role of farnesoid X receptor and bile acids in alcoholic liver disease
- (2015) Sharon Manley et al. Acta Pharmaceutica Sinica B
- Novel Markers to Delineate Murine M1 and M2 Macrophages
- (2015) Kyle A. Jablonski et al. PLoS One
- Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
- (2014) Yonit Lavin et al. CELL
- Nuclear Receptors, RXR, and the Big Bang
- (2014) Ronald M. Evans et al. CELL
- Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation
- (2014) Shinya U. Amano et al. Cell Metabolism
- The Fatty Acid–Bile Acid Conjugate Aramchol Reduces Liver Fat Content in Patients With Nonalcoholic Fatty Liver Disease
- (2014) Rifaat Safadi et al. Clinical Gastroenterology and Hepatology
- Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding
- (2014) K. R. Markan et al. DIABETES
- Expression of Liver X Receptor Correlates with Intrahepatic Inflammation and Fibrosis in Patients with Nonalcoholic Fatty Liver Disease
- (2014) Sang Bong Ahn et al. DIGESTIVE DISEASES AND SCIENCES
- A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis
- (2014) J. Gautheron et al. EMBO Molecular Medicine
- Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance
- (2014) Tom Luedde et al. GASTROENTEROLOGY
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
- (2014) Jia Xue et al. IMMUNITY
- Macrophages, Immunity, and Metabolic Disease
- (2014) Joanne C. McNelis et al. IMMUNITY
- Cyclophilin inhibition as potential therapy for liver diseases
- (2014) Nikolai V. Naoumov JOURNAL OF HEPATOLOGY
- Hepatic toll-like receptor 4 expression is associated with portal inflammation and fibrosis in patients with NAFLD
- (2014) Umberto Vespasiani-Gentilucci et al. LIVER INTERNATIONAL
- Liver X receptors in lipid metabolism: opportunities for drug discovery
- (2014) Cynthia Hong et al. NATURE REVIEWS DRUG DISCOVERY
- Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity
- (2014) Sophie Leclercq et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome
- (2014) Hannele Yki-Järvinen Lancet Diabetes & Endocrinology
- Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
- (2013) Bart Staels et al. HEPATOLOGY
- Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia
- (2013) Pooja Jha et al. HEPATOLOGY
- Food-derived peroxidized fatty acids may trigger hepatic inflammation: A novel hypothesis to explain steatohepatitis
- (2013) Therese Böhm et al. JOURNAL OF HEPATOLOGY
- Cell-specific PPARγ deficiency establishes anti-inflammatory and anti-fibrogenic properties for this nuclear receptor in non-parenchymal liver cells
- (2013) Eva Morán-Salvador et al. JOURNAL OF HEPATOLOGY
- SCD1 activity in muscle increases triglyceride PUFA content, exercise capacity, and PPARδ expression in mice
- (2013) Michael P. Rogowski et al. JOURNAL OF LIPID RESEARCH
- Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis
- (2013) Laura J. Dixon et al. PLoS One
- Hepatic Crown-Like Structure: A Unique Histological Feature in Non-Alcoholic Steatohepatitis in Mice and Humans
- (2013) Michiko Itoh et al. PLoS One
- The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis
- (2012) Jixi Li et al. CELL
- Hyperresponsivity to Low-Dose Endotoxin during Progression to Nonalcoholic Steatohepatitis Is Regulated by Leptin-Mediated Signaling
- (2012) Kento Imajo et al. Cell Metabolism
- The Cholesterol Derivative 27-Hydroxycholesterol Reduces Steatohepatitis in Mice
- (2012) Veerle Bieghs et al. GASTROENTEROLOGY
- Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice
- (2012) Dewei Ye et al. GUT
- Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice
- (2012) Yuan Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis
- (2012) Anne Leroux et al. JOURNAL OF HEPATOLOGY
- Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis
- (2012) Saurabh Chatterjee et al. JOURNAL OF HEPATOLOGY
- Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis
- (2012) Laura J Dixon et al. LABORATORY INVESTIGATION
- Internalization of Modified Lipids by CD36 and SR-A Leads to Hepatic Inflammation and Lysosomal Cholesterol Storage in Kupffer Cells
- (2012) Veerle Bieghs et al. PLoS One
- Nuclear receptor PPAR -regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis
- (2012) Y. J. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation
- (2012) Radina Kostadinova et al. Cell and Bioscience
- Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
- (2011) G. Vernon et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Peroxisome Proliferator–Activated Receptor-α Gene Level Differently Affects Lipid Metabolism and Inflammation in Apolipoprotein E2 Knock-In Mice
- (2011) Fanny Lalloyer et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway
- (2011) Matthew J. Potthoff et al. Cell Metabolism
- Activation of Liver X Receptors Attenuates Endotoxin-Induced Liver Injury in Mice with Nonalcoholic Fatty Liver Disease
- (2011) Yuan Liu et al. DIGESTIVE DISEASES AND SCIENCES
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- (2011) Eva Morán-Salvador et al. FASEB JOURNAL
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- (2011) João Soeiro Teodoro et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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- (2010) Jerrold M. Olefsky et al. Annual Review of Physiology
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- (2010) Kristiaan Wouters et al. FEBS LETTERS
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- (2010) Kouichi Miura et al. GASTROENTEROLOGY
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- (2010) Simon W. Beaven et al. GASTROENTEROLOGY
- Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study
- (2010) Christopher D. Williams et al. GASTROENTEROLOGY
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- (2010) N. Venteclef et al. GENES & DEVELOPMENT
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- (2010) Brent A. Neuschwander-Tetri HEPATOLOGY
- Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
- (2010) Herbert Tilg et al. HEPATOLOGY
- Peroxisome proliferator-activated receptors gamma reverses hepatic nutritional fibrosis in mice and suppresses activation of hepatic stellate cells in vitro
- (2010) Jun Yu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Molecular mechanisms of necroptosis: an ordered cellular explosion
- (2010) Peter Vandenabeele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cyclophilin D in mitochondrial pathophysiology
- (2009) Valentina Giorgio et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis
- (2009) Songwen Zhang et al. JOURNAL OF HEPATOLOGY
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- (2009) Francisco Caballero et al. JOURNAL OF HEPATOLOGY
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- (2009) Sabrina Cipriani et al. JOURNAL OF LIPID RESEARCH
- Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses
- (2009) Eduardo J Villablanca et al. NATURE MEDICINE
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
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- (2009) Philippe Lefebvre et al. PHYSIOLOGICAL REVIEWS
- Quantitative expression patterns of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) protein in mice
- (2008) Elizabeth E. Girroir et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism
- (2008) Matthew T Flowers et al. CURRENT OPINION IN LIPIDOLOGY
- Fibroblast Growth Factor 21 Corrects Obesity in Mice
- (2008) Tamer Coskun et al. ENDOCRINOLOGY
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