Extracellular Matrices and Cancer-Associated Fibroblasts: Targets for Cancer Diagnosis and Therapy?
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Extracellular Matrices and Cancer-Associated Fibroblasts: Targets for Cancer Diagnosis and Therapy?
Authors
Keywords
-
Journal
Cancers
Volume 13, Issue 14, Pages 3466
Publisher
MDPI AG
Online
2021-07-12
DOI
10.3390/cancers13143466
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Multifunctional intracellular matrix metalloproteinases: implications in disease
- (2021) Wesam Bassiouni et al. FEBS Journal
- Pharmacological normalization of pancreatic cancer-associated fibroblast secretome impairs pro-metastatic cross-talk with macrophages
- (2021) R. Samain et al. Cellular and Molecular Gastroenterology and Hepatology
- Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
- (2021) Yang Chen et al. CANCER CELL
- FAK signaling in cancer-associated fibroblasts promotes breast cancer cell migration and metastasis by exosomal miRNAs-mediated intercellular communication
- (2020) Hsin-Jung Wu et al. ONCOGENE
- Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
- (2020) Floriane Pelon et al. Nature Communications
- Antifibrotic therapy to normalize the tumor microenvironment
- (2020) Anette Hauge et al. Journal of Translational Medicine
- Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer
- (2020) Ozge Saatci et al. Nature Communications
- Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth
- (2020) Sarah Davidson et al. Cell Reports
- Randomised phase II trial of gemcitabine and nab-paclitaxel with necuparanib or placebo in untreated metastatic pancreas ductal adenocarcinoma
- (2020) Eileen M. O'Reilly et al. EUROPEAN JOURNAL OF CANCER
- Targeting focal adhesion kinase in cancer cells and the tumor microenvironment
- (2020) James M. Murphy et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix
- (2020) Honglin Jiang et al. JOURNAL OF CLINICAL INVESTIGATION
- Randomized Phase III Trial of Pegvorhyaluronidase Alfa With Nab-Paclitaxel Plus Gemcitabine for Patients With Hyaluronan-High Metastatic Pancreatic Adenocarcinoma
- (2020) Eric Van Cutsem et al. JOURNAL OF CLINICAL ONCOLOGY
- Rock inhibition promotes NaV1.5 sodium channel-dependent SW620 colon cancer cell invasiveness
- (2020) Lucile Poisson et al. Scientific Reports
- FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer
- (2020) Sonia Zaghdoudi et al. EMBO Molecular Medicine
- Mechanical Control of Cell Proliferation Increases Resistance to Chemotherapeutic Agents
- (2020) Ilaria Francesca Rizzuti et al. PHYSICAL REVIEW LETTERS
- TGF-β Mediated Immune Evasion in Cancer—Spotlight on Cancer-Associated Fibroblasts
- (2020) Parisa Ghahremanifard et al. Cancers
- A comparative assessment of the effects of integrin inhibitor cilengitide on primary culture of head and neck squamous cell carcinoma (HNSCC) and HNSCC cell lines
- (2019) L. Zhang et al. Clinical & Translational Oncology
- Inhibition of LOXL2 Enhances the Radiosensitivity of Castration-Resistant Prostate Cancer Cells Associated with the Reversal of the EMT Process
- (2019) Peng Xie et al. Biomed Research International
- Hypoxic cancer–associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling
- (2019) Fernanda G. Kugeratski et al. Science Signaling
- Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer
- (2019) Ivy X. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma
- (2019) Andrew J. Gunderson et al. PLoS One
- Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology
- (2019) Neel I. Nissen et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Phase IB/II Randomized Study of FOLFIRINOX Plus Pegylated Recombinant Human Hyaluronidase Versus FOLFIRINOX Alone in Patients With Metastatic Pancreatic Adenocarcinoma: SWOG S1313
- (2019) Ramesh K. Ramanathan et al. JOURNAL OF CLINICAL ONCOLOGY
- Mobilization of CD8+ T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer
- (2019) Yongwoo David Seo et al. CLINICAL CANCER RESEARCH
- Bioengineered scaffolds for 3D culture demonstrate extracellular matrix-mediated mechanisms of chemotherapy resistance in glioblastoma
- (2019) Weikun Xiao et al. MATRIX BIOLOGY
- Akt inhibitor SC66 promotes cell sensitivity to cisplatin in chemoresistant ovarian cancer cells through inhibition of COL11A1 expression
- (2019) Yi-Hui Wu et al. Cell Death & Disease
- Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non–Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion
- (2019) Jing Hao et al. NEOPLASIA
- Integrins, CAFs and Mechanical Forces in the Progression of Cancer
- (2019) Imjoo Jang et al. Cancers
- COL6A1 promotes metastasis and predicts poor prognosis in patients with pancreatic cancer
- (2019) Kwabena Owusu‑Ansah et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
- (2019) Ela Elyada et al. Cancer Discovery
- Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant
- (2019) Pino Bordignon et al. Cell Reports
- FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
- (2019) Carlos J Diaz Osterman et al. eLife
- Extracellular Matrix Alterations in Metastatic Processes
- (2019) Paolillo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Single-cell RNA sequencing reveals stromal evolution into LRRC15+ myofibroblasts as a determinant of patient response to cancer immunotherapy
- (2019) Claudia X Dominguez et al. Cancer Discovery
- Metabolites of type I, II, III, and IV collagen may serve as markers of disease activity in axial spondyloarthritis
- (2019) Markéta Hušáková et al. Scientific Reports
- Pituitary tumour fibroblast-derived cytokines influence tumour aggressiveness
- (2019) Pedro Marques et al. ENDOCRINE-RELATED CANCER
- Fibronectin in Cancer: Friend or Foe
- (2019) Tsung-Cheng Lin et al. Cells
- A core matrisome gene signature predicts cancer outcome
- (2018) Arseniy E Yuzhalin et al. BRITISH JOURNAL OF CANCER
- The extracellular matrix as a key regulator of intracellular signalling networks
- (2018) Jordan F Hastings et al. BRITISH JOURNAL OF PHARMACOLOGY
- Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma
- (2018) Rajani Kanteti et al. CANCER BIOLOGY & THERAPY
- Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer
- (2018) Ana Costa et al. CANCER CELL
- Soluble stroma‐related biomarkers of pancreatic cancer
- (2018) Andrea Resovi et al. EMBO Molecular Medicine
- Phase I study of the heparanase inhibitor Roneparstat: an innovative approach for multiple myeloma therapy
- (2018) Monica Galli et al. HAEMATOLOGICA
- Overexpression of collagen type V α1 chain in human breast invasive ductal carcinoma is mediated by TGF-β1
- (2018) Weimin Ren et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Extracellular matrix proteins as diagnostic markers of breast carcinoma
- (2018) Marta Giussani et al. JOURNAL OF CELLULAR PHYSIOLOGY
- HALO 202: Randomized Phase II Study of PEGPH20 Plus Nab-Paclitaxel/Gemcitabine Versus Nab-Paclitaxel/Gemcitabine in Patients With Untreated, Metastatic Pancreatic Ductal Adenocarcinoma
- (2018) Sunil R. Hingorani et al. JOURNAL OF CLINICAL ONCOLOGY
- Extracellular matrix: The driving force of mammalian diseases
- (2018) Renato V. Iozzo et al. MATRIX BIOLOGY
- Matrix Metalloproteinase Inhibitors in Cancer Therapy: Turning Past Failures Into Future Successes
- (2018) Arthur Winer et al. MOLECULAR CANCER THERAPEUTICS
- Digesting a Path Forward: The Utility of Collagenase Tumor Treatment for Improved Drug Delivery
- (2018) Aaron Dolor et al. MOLECULAR PHARMACEUTICS
- TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
- (2018) Daniele V. F. Tauriello et al. NATURE
- Mechanisms and impact of altered tumour mechanics
- (2018) Hamid Mohammadi et al. NATURE CELL BIOLOGY
- The cancer matrisome: From comprehensive characterization to biomarker discovery
- (2018) Alexandra M. Socovich et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers
- (2018) Anne-Marie Givel et al. Nature Communications
- Phase I study of the heparanase inhibitor Roneparstat: an innovative approach for multiple myeloma therapy
- (2018) Monica Galli et al. HAEMATOLOGICA
- Fibronectin Promotes the Malignancy of Glioma Stem-Like Cells Via Modulation of Cell Adhesion, Differentiation, Proliferation and Chemoresistance
- (2018) Qi Yu et al. Frontiers in Molecular Neuroscience
- Tensile forces drive a reversible fibroblast-to-myofibroblast transition during tissue growth in engineered clefts
- (2018) Philip Kollmannsberger et al. Science Advances
- Defining the Role of Solid Stress and Matrix Stiffness in Cancer Cell Proliferation and Metastasis
- (2018) Maria Kalli et al. Frontiers in Oncology
- TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
- (2018) Sanjeev Mariathasan et al. NATURE
- International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature
- (2018) Thomas Günther et al. PHARMACOLOGICAL REVIEWS
- Role of Extracellular Matrix in Development and Cancer Progression
- (2018) Cameron Walker et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Efficient PD-L1 gene silence promoted by hyaluronidase for cancer immunotherapy
- (2018) Xiuwen Guan et al. JOURNAL OF CONTROLLED RELEASE
- Inter- and intra-tumoral heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma
- (2018) Cindy Neuzillet et al. JOURNAL OF PATHOLOGY
- Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing
- (2018) Michael Bartoschek et al. Nature Communications
- Cancer associated fibroblasts: is the force the path to the dark side?
- (2018) Jorge Barbazán et al. CURRENT OPINION IN CELL BIOLOGY
- Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor
- (2017) Tom Holvoet et al. GASTROENTEROLOGY
- Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer
- (2017) Angela Chou et al. GUT
- Inhibition of group 1 p21-activated kinases suppresses pancreatic stellate cell activation and increases survival of mice with pancreatic cancer
- (2017) Dannel Yeo et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer-associated fibroblasts lead tumor invasion through integrin-β3–dependent fibronectin assembly
- (2017) Youmna Attieh et al. JOURNAL OF CELL BIOLOGY
- Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
- (2017) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Plasma Biomarker Panel to Identify Surgically Resectable Early-Stage Pancreatic Cancer
- (2017) Seetharaman Balasenthil et al. JNCI-Journal of the National Cancer Institute
- Proteoglycans remodeling in cancer: Underlying molecular mechanisms
- (2017) Achilleas D. Theocharis et al. MATRIX BIOLOGY
- Cell-derived matrices for studying cell proliferation and directional migration in a complex 3D microenvironment
- (2017) Riina Kaukonen et al. Nature Protocols
- SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer
- (2017) N L E Harris et al. ONCOGENE
- A Phase II, Randomized, Double‐Blind, Placebo‐Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second‐Line Treatment of MetastaticKRASMutant Colorectal Adenocarcinoma
- (2017) J. Randolph Hecht et al. ONCOLOGIST
- A Phase II Randomized, Double‐Blind, Placebo‐Controlled Study of Simtuzumab or Placebo in Combination with Gemcitabine for the First‐Line Treatment of Pancreatic Adenocarcinoma
- (2017) Al B. Benson et al. ONCOLOGIST
- Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
- (2017) Claire Vennin et al. Science Translational Medicine
- Matrix Metalloproteinases: A challenging paradigm of cancer management
- (2017) Ali Alaseem et al. SEMINARS IN CANCER BIOLOGY
- Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress
- (2017) Jeremy Soon Kiat Chan et al. Cell Death & Disease
- An extracellular matrix-related prognostic and predictive indicator for early-stage non-small cell lung cancer
- (2017) Su Bin LIM et al. Nature Communications
- α3 Chains of type V collagen regulate breast tumour growth via glypican-1
- (2017) Guorui Huang et al. Nature Communications
- Fibronectin-guided migration of carcinoma collectives
- (2017) Sandeep Gopal et al. Nature Communications
- Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
- (2017) Julienne L. Carstens et al. Nature Communications
- Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface
- (2017) HaoRan Tang et al. Nature Communications
- Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane
- (2017) Alexandros Glentis et al. Nature Communications
- Collagen type 1 promotes survival of human breast cancer cells by overexpressing Kv10.1 potassium and Orai1 calcium channels through DDR1-dependent pathway
- (2017) Mehdi Badaoui et al. Oncotarget
- Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases
- (2017) Chen Rachman-Tzemah et al. Cell Reports
- A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts
- (2017) Max Nobis et al. Cell Reports
- Agrin as a Mechanotransduction Signal Regulating YAP through the Hippo Pathway
- (2017) Sayan Chakraborty et al. Cell Reports
- Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence
- (2017) Janusz Franco-Barraza et al. eLife
- A Plasma Biomarker Panel to Identify Surgically Resectable Early-Stage Pancreatic Cancer
- (2017) Seetharaman Balasenthil et al. JNCI-Journal of the National Cancer Institute
- Mutational Signatures Are Critical for Proper Estimation of Purifying Selection Pressures in Cancer Somatic Mutation Data When Using the dN/dS Metric
- (2017) Jimmy Van den Eynden et al. Frontiers in Genetics
- ROCK inhibition with Fasudil induces beta-catenin nuclear translocation and inhibits cell migration of MDA-MB 231 human breast cancer cells
- (2017) Fabiana Sélos Guerra et al. Scientific Reports
- Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities
- (2016) Jessie L.-S. Au et al. ADVANCED DRUG DELIVERY REVIEWS
- The extracellular matrix in breast cancer
- (2016) Jacob Insua-Rodríguez et al. ADVANCED DRUG DELIVERY REVIEWS
- Structural ECM components in the premetastatic and metastatic niche
- (2016) Anette M. Høye et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Glycans and glycoproteins as specific biomarkers for cancer
- (2016) Muchena J. Kailemia et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600Eand Pten Loss
- (2016) Lee Ann Jolly et al. CANCER RESEARCH
- ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth
- (2016) Nicola Rath et al. EMBO Molecular Medicine
- The hallmarks of CAFs in cancer invasion
- (2016) Youmna Attieh et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Plasma matrix metalloproteinase 9 as an early surrogate biomarker of advanced colorectal neoplasia
- (2016) Antonio Z. Gimeno-García et al. Gastroenterologia y Hepatologia
- Vitamin D receptor expression and associated gene signature in tumour stromal fibroblasts predict clinical outcome in colorectal cancer
- (2016) Gemma Ferrer-Mayorga et al. GUT
- Integrin-mediated mechanotransduction
- (2016) Zhiqi Sun et al. JOURNAL OF CELL BIOLOGY
- Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche
- (2016) Olivier Govaere et al. JOURNAL OF HEPATOLOGY
- Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer
- (2016) Michela Capello et al. JNCI-Journal of the National Cancer Institute
- Fibroblasts for all seasons
- (2016) Erwin F. Wagner NATURE
- Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
- (2016) Sebastian R. Nielsen et al. NATURE CELL BIOLOGY
- Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity
- (2016) Alberto Elosegui-Artola et al. NATURE CELL BIOLOGY
- Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
- (2016) Hanane Laklai et al. NATURE MEDICINE
- Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy
- (2016) Hong Jiang et al. NATURE MEDICINE
- High expression of fibronectin is associated with poor prognosis, cell proliferation and malignancy via the NF-κB/p53-apoptosis signaling pathway in colorectal cancer
- (2016) Wenzhong Yi et al. ONCOLOGY REPORTS
- Role of periostin in esophageal, gastric and colon cancer
- (2016) Tadeusz Moniuszko et al. Oncology Letters
- Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription
- (2016) Riina Kaukonen et al. Nature Communications
- ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion
- (2016) Antonios Chronopoulos et al. Nature Communications
- Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts
- (2016) Siham Moatassim-Billah et al. Oncotarget
- Antitumor efficacy of the heparan sulfate mimic roneparstat (SST0001) against sarcoma models involves multi-target inhibition of receptor tyrosine kinases
- (2016) Giuliana Cassinelli et al. Oncotarget
- Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection
- (2016) Cole R. Drifka et al. Oncotarget
- Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer
- (2016) Michela Capello et al. JNCI-Journal of the National Cancer Institute
- SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells
- (2016) David A. Tumbarello et al. PLoS One
- Excessive collagen turnover products are released during colorectal cancer progression and elevated in serum from metastatic colorectal cancer patients
- (2016) S. N. Kehlet et al. Scientific Reports
- Collagen cross-linking: insights on the evolution of metazoan extracellular matrix
- (2016) Fernando Rodriguez-Pascual et al. Scientific Reports
- Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer
- (2015) Becky K. Brisson et al. AMERICAN JOURNAL OF PATHOLOGY
- Cilengitide combined with cetuximab and platinum-based chemotherapy as first-line treatment in advanced non-small-cell lung cancer (NSCLC) patients: results of an open-label, randomized, controlled phase II study (CERTO)
- (2015) J. Vansteenkiste et al. ANNALS OF ONCOLOGY
- Combining conventional and stroma-derived tumour markers in pancreatic ductal adenocarcinoma
- (2015) Oskar Franklin et al. Cancer Biomarkers
- Tissue Transglutaminase Mediated Tumor-Stroma Interaction Promotes Pancreatic Cancer Progression
- (2015) J. Lee et al. CLINICAL CANCER RESEARCH
- Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer
- (2015) C. J. Whatcott et al. CLINICAL CANCER RESEARCH
- The regulation of immune cell trafficking by the extracellular matrix
- (2015) Rupert Hallmann et al. CURRENT OPINION IN CELL BIOLOGY
- Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy
- (2015) Bryan W Miller et al. EMBO Molecular Medicine
- Pharmacological targeting of the protein synthesis mTOR/4E-BP1 pathway in cancer-associated fibroblasts abrogates pancreatic tumour chemoresistance
- (2015) C. Duluc et al. EMBO Molecular Medicine
- Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities
- (2015) Venessa T. Chin et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration
- (2015) I. Acerbi et al. Integrative Biology
- Schizandrin inhibits fibrosis and epithelial–mesenchymal transition in transforming growth factor-β1-stimulated AML12 cells
- (2015) Ji-hyun Park et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasiveness in gastric cancer
- (2015) Daisuke Izumi et al. INTERNATIONAL JOURNAL OF CANCER
- Laminin 3 expression as a prognostic factor and a predictive marker of chemoresistance in colorectal cancer
- (2015) S. Fukazawa et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
- (2015) Yulong Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma
- (2015) D. Pankova et al. MOLECULAR CANCER RESEARCH
- Tumour exosome integrins determine organotropic metastasis
- (2015) Ayuko Hoshino et al. NATURE
- Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
- (2015) Bruno Costa-Silva et al. NATURE CELL BIOLOGY
- Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma
- (2015) Richard A Moffitt et al. NATURE GENETICS
- Stromal fibroblasts facilitate cancer cell invasion by a novel invadopodia-independent matrix degradation process
- (2015) H Cao et al. ONCOGENE
- Addressing the challenges of pancreatic cancer: Future directions for improving outcomes
- (2015) Manuel Hidalgo et al. PANCREATOLOGY
- Targeting the TGFβ pathway for cancer therapy
- (2015) Cindy Neuzillet et al. PHARMACOLOGY & THERAPEUTICS
- Tumor-extracellular matrix interactions: Identification of tools associated with breast cancer progression
- (2015) Marta Giussani et al. SEMINARS IN CANCER BIOLOGY
- Extracellular matrix as target for antitumor therapy
- (2015) Andras Jeney et al. OncoTargets and Therapy
- The prognostic value of stroma in pancreatic cancer in patients receiving adjuvant therapy
- (2015) Katherine M. Bever et al. HPB
- Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma
- (2015) Pi-Lin Sung et al. Oncotarget
- Hyaluronan, Inflammation, and Breast Cancer Progression
- (2015) Kathryn L. Schwertfeger et al. Frontiers in Immunology
- Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer
- (2015) Derek C. Marshall et al. PLoS One
- Prognostic impact of a compartment-specific angiogenic marker profile in patients with pancreatic cancer
- (2015) Christoph Kahlert et al. Oncotarget
- Cellular traction stresses mediate extracellular matrix degradation by invadopodia
- (2014) Rachel J. Jerrell et al. Acta Biomaterialia
- Abituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients withKRASwild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trial
- (2014) E. Élez et al. ANNALS OF ONCOLOGY
- Cisplatin, 5-fluorouracil, and cetuximab (PFE) with or without cilengitide in recurrent/metastatic squamous cell carcinoma of the head and neck: results of the randomized phase I/II ADVANTAGE trial (phase II part)
- (2014) J. B. Vermorken et al. ANNALS OF ONCOLOGY
- Matrikines from basement membrane collagens: A new anti-cancer strategy
- (2014) Jean Claude Monboisse et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- 3D Traction Stresses Activate Protease-Dependent Invasion of Cancer Cells
- (2014) Aereas Aung et al. BIOPHYSICAL JOURNAL
- 3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence
- (2014) Kristin M. Riching et al. BIOPHYSICAL JOURNAL
- Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver
- (2014) Alexandra Naba et al. BMC CANCER
- Serum endostatin levels are elevated in colorectal cancer and correlate with invasion and systemic inflammatory markers
- (2014) T Kantola et al. BRITISH JOURNAL OF CANCER
- Compression of Pancreatic Tumor Blood Vessels by Hyaluronan Is Caused by Solid Stress and Not Interstitial Fluid Pressure
- (2014) Vikash P. Chauhan et al. CANCER CELL
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- Force Engages Vinculin and Promotes Tumor Progression by Enhancing PI3K Activation of Phosphatidylinositol (3,4,5)-Triphosphate
- (2014) Matthew G. Rubashkin et al. CANCER RESEARCH
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
- (2014) Mara H. Sherman et al. CELL
- Physical and mechanical regulation of macrophage phenotype and function
- (2014) Frances Y. McWhorter et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Prevailing Role of Contact Guidance in Intrastromal T-cell Trapping in Human Pancreatic Cancer
- (2014) N. Hartmann et al. CLINICAL CANCER RESEARCH
- SPARC in Tumor Pathophysiology and as a Potential Therapeutic Target
- (2014) Jianguo Feng et al. CURRENT PHARMACEUTICAL DESIGN
- The extracellular matrix modulates the hallmarks of cancer
- (2014) M. W. Pickup et al. EMBO REPORTS
- Hyaluronidase-1 expression promotes lung metastasis in syngeneic mouse tumor models without affecting accumulation of small hyaluronan oligosaccharides in tumor interstitial fluid
- (2014) A. Schmaus et al. GLYCOBIOLOGY
- Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer
- (2014) Nina R. Shah et al. GYNECOLOGIC ONCOLOGY
- Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma
- (2014) Carmen Chak-Lui Wong et al. HEPATOLOGY
- Platelet-derived Growth Factor Primes Cancer-associated Fibroblasts for Apoptosis
- (2014) Sumera Rizvi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function
- (2014) Christine Jean et al. JOURNAL OF CELL BIOLOGY
- Fibroblast heterogeneity in the cancer wound
- (2014) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation
- (2014) A. Gaggar et al. JOURNAL OF IMMUNOLOGY
- Proteomic View of Basement Membranes from Human Retinal Blood Vessels, Inner Limiting Membranes, and Lens Capsules
- (2014) Guy Uechi et al. JOURNAL OF PROTEOME RESEARCH
- Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma
- (2014) Ru Chen et al. LABORATORY INVESTIGATION
- Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial
- (2014) Roger Stupp et al. LANCET ONCOLOGY
- The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling
- (2014) Megan S. Lord et al. MATRIX BIOLOGY
- FAK Inhibition Disrupts a 5 Integrin Signaling Axis Controlling Anchorage-Independent Ovarian Carcinoma Growth
- (2014) I. Tancioni et al. MOLECULAR CANCER THERAPEUTICS
- Endostatin inhibits the tumorigenesis of hemangioendothelioma via downregulation of CXCL1
- (2014) Lifang Guo et al. MOLECULAR CARCINOGENESIS
- Physical influences of the extracellular environment on cell migration
- (2014) Guillaume Charras et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Extracellular matrix assembly: a multiscale deconstruction
- (2014) Janna K. Mouw et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Remodelling the extracellular matrix in development and disease
- (2014) Caroline Bonnans et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Heparanase multiple effects in cancer
- (2014) Yona Nadir et al. THROMBOSIS RESEARCH
- Role of α5β1 Integrin Up-regulation in Radiation-Induced Invasion by Human Pancreatic Cancer Cells
- (2014) Hongren Yao et al. Translational Oncology
- Extracellular Matrix Modulates Angiogenesis in Physiological and Pathological Conditions
- (2014) Anna Neve et al. Biomed Research International
- Collagen VI and Hyaluronan: The Common Role in Breast Cancer
- (2014) Evgenia Karousou et al. Biomed Research International
- FAK and HAS Inhibition Synergistically Decrease Colon Cancer Cell Viability and Affect Expression of Critical Genes
- (2013) Melissa Heffler et al. Anti-Cancer Agents in Medicinal Chemistry
- Extracellular matrix specific protein fingerprints measured in serum can separate pancreatic cancer patients from healthy controls
- (2013) Nicholas Willumsen et al. BMC CANCER
- Extracellular matrix components in breast cancer progression and metastasis
- (2013) Thordur Oskarsson BREAST
- LOXL2 expression is associated with invasiveness and negatively influences survival in breast cancer patients
- (2013) Sung Gwe Ahn et al. BREAST CANCER RESEARCH AND TREATMENT
- Collagen type XI α1 facilitates head and neck squamous cell cancer growth and invasion
- (2013) J C Sok et al. BRITISH JOURNAL OF CANCER
- Stromal expression of SPARC in pancreatic adenocarcinoma
- (2013) Cindy Neuzillet et al. CANCER AND METASTASIS REVIEWS
- The stromal compartments in pancreatic cancer: Are there any therapeutic targets?
- (2013) Serena Lunardi et al. CANCER LETTERS
- Docetaxel Conjugate Nanoparticles That Target -Smooth Muscle Actin-Expressing Stromal Cells Suppress Breast Cancer Metastasis
- (2013) M. Murakami et al. CANCER RESEARCH
- LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis
- (2013) T. R. Cox et al. CANCER RESEARCH
- Stromally Derived Lysyl Oxidase Promotes Metastasis of Transforming Growth Factor- -Deficient Mouse Mammary Carcinomas
- (2013) M. W. Pickup et al. CANCER RESEARCH
- Coevolution of Solid Stress and Interstitial Fluid Pressure in Tumors During Progression: Implications for Vascular Collapse
- (2013) Triantafyllos Stylianopoulos et al. CANCER RESEARCH
- Unraveling galectin-1 as a novel therapeutic target for cancer
- (2013) Lucile Astorgues-Xerri et al. CANCER TREATMENT REVIEWS
- Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
- (2013) A. Jimeno et al. CLINICAL CANCER RESEARCH
- Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma
- (2013) Abasi Ene–Obong et al. GASTROENTEROLOGY
- Fibronectin expression in carcinoma cells correlates with tumor aggressiveness and poor clinical outcome in patients with invasive breast cancer
- (2013) Young Kyung Bae et al. HUMAN PATHOLOGY
- Intercellular Communication by Exosome-Derived microRNAs in Cancer
- (2013) Bethany Hannafon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force
- (2013) Katarina Wolf et al. JOURNAL OF CELL BIOLOGY
- Podoplanin, α-Smooth Muscle Actin or S100A4 Expressing Cancer-Associated Fibroblasts Are Associated with Different Prognosis in Colorectal Cancers
- (2013) Song-Yi Choi et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- Signalling pathways linking integrins with cell cycle progression
- (2013) Paulina Moreno-Layseca et al. MATRIX BIOLOGY
- Unraveling the therapeutic potential of the Hedgehog pathway in cancer
- (2013) Dereck Amakye et al. NATURE MEDICINE
- Exploring mechanisms of FGF signalling through the lens of structural biology
- (2013) Regina Goetz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer
- (2013) Y-H Wu et al. ONCOGENE
- Neoplastic and Stromal Cells Contribute to an Extracellular Matrix Gene Expression Profile Defining a Breast Cancer Subtype Likely to Progress
- (2013) Tiziana Triulzi et al. PLoS One
- Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
- (2013) C. Feig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial
- (2012) A. Huijbers et al. ANNALS OF ONCOLOGY
- Serum matrix metalloproteinase 9 and colorectal neoplasia: a community-based evaluation of a potential diagnostic test
- (2012) S Wilson et al. BRITISH JOURNAL OF CANCER
- Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma
- (2012) Ru Chen et al. CANCER BIOLOGY & THERAPY
- Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation
- (2012) Alexandre Calon et al. CANCER CELL
- Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
- (2012) Paolo P. Provenzano et al. CANCER CELL
- Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression
- (2012) Kristy K. Ward et al. CLINICAL & EXPERIMENTAL METASTASIS
- The Impact of the Activated Stroma on Pancreatic Ductal Adenocarcinoma Biology and Therapy Resistance
- (2012) Mert Erkan et al. CURRENT MOLECULAR MEDICINE
- Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
- (2012) Michael A Jacobetz et al. GUT
- Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors
- (2012) Hélène Salmon et al. JOURNAL OF CLINICAL INVESTIGATION
- Substrate Rigidity Regulates Human T Cell Activation and Proliferation
- (2012) R. S. O'Connor et al. JOURNAL OF IMMUNOLOGY
- ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells
- (2012) David A Tumbarello et al. Molecular Cancer
- The role of stroma in pancreatic cancer: diagnostic and therapeutic implications
- (2012) Mert Erkan et al. Nature Reviews Gastroenterology & Hepatology
- Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells
- (2012) XIAOXIAO YANG et al. ONCOLOGY REPORTS
- Progressive Increase of Matrix Metalloprotease-9 and Interleukin-8 Serum Levels during Carcinogenic Process in Human Colorectal Tract
- (2012) Fiorella Biasi et al. PLoS One
- Desmoplasia in Pancreatic Cancer. Can We Fight It?
- (2012) E. E. Merika et al. Gastroenterology Research and Practice
- Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma
- (2011) Matthew W. Conklin et al. AMERICAN JOURNAL OF PATHOLOGY
- FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
- (2011) Hyung-Ok Lee et al. BMC CANCER
- Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth
- (2011) Michael S. Samuel et al. CANCER CELL
- Role of Heparanase in Radiation-Enhanced Invasiveness of Pancreatic Carcinoma
- (2011) A. Meirovitz et al. CANCER RESEARCH
- Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis
- (2011) J. L. Hood et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis
- (2011) Joseph P. Ritchie et al. CLINICAL CANCER RESEARCH
- Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
- (2011) Annika Armulik et al. DEVELOPMENTAL CELL
- Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
- (2011) T. R. Cox et al. Disease Models & Mechanisms
- Retinoic Acid–Induced Pancreatic Stellate Cell Quiescence Reduces Paracrine Wnt–β-Catenin Signaling to Slow Tumor Progression
- (2011) Fieke E.M. Froeling et al. GASTROENTEROLOGY
- Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling
- (2011) P. P. Provenzano et al. JOURNAL OF CELL SCIENCE
- Fibrous Stroma Is Associated with Poorer Prognosis in Lung Squamous Cell Carcinoma Patients
- (2011) Yusuke Takahashi et al. Journal of Thoracic Oncology
- Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration
- (2011) Stephen P. Evanko et al. MATRIX BIOLOGY
- Endothelial Cell-Pericyte Interactions Stimulate Basement Membrane Matrix Assembly: Influence on Vascular Tube Remodeling, Maturation, and Stabilization
- (2011) Amber N. Stratman et al. MICROSCOPY AND MICROANALYSIS
- The Matrisome:In SilicoDefinition andIn VivoCharacterization by Proteomics of Normal and Tumor Extracellular Matrices
- (2011) Alexandra Naba et al. MOLECULAR & CELLULAR PROTEOMICS
- Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment
- (2011) J. B. Stokes et al. MOLECULAR CANCER THERAPEUTICS
- Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
- (2011) Peter Carmeliet et al. NATURE REVIEWS DRUG DISCOVERY
- ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors
- (2011) P. L. Bollyky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systematic Analysis of Breast Cancer Morphology Uncovers Stromal Features Associated with Survival
- (2011) A. H. Beck et al. Science Translational Medicine
- Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions
- (2011) R. O. Hynes et al. Cold Spring Harbor Perspectives in Biology
- Extracellular Matrix Degradation and Remodeling in Development and Disease
- (2011) P. Lu et al. Cold Spring Harbor Perspectives in Biology
- Inflammatory Alterations of the Extracellular Matrix in the Tumor Microenvironment
- (2011) Junko Iijima et al. Cancers
- Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis
- (2010) Xiaofeng Zhao et al. ADVANCED DRUG DELIVERY REVIEWS
- Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation
- (2010) Jessica McCready et al. BMC CANCER
- Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization
- (2010) N. Kobayashi et al. CANCER RESEARCH
- Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model
- (2010) Yuan Wen et al. CANCER SCIENCE
- Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
- (2010) Kai Kessenbrock et al. CELL
- Tumors as Organs: Complex Tissues that Interface with the Entire Organism
- (2010) Mikala Egeblad et al. DEVELOPMENTAL CELL
- The diagnostic value of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of matrix metalloproteinases 1 (TIMP-1) determination in the sera of colorectal adenoma and cancer patients
- (2010) Barbara Mroczko et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia
- (2010) Marie Schoumacher et al. JOURNAL OF CELL BIOLOGY
- Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models
- (2010) C. B. Thompson et al. MOLECULAR CANCER THERAPEUTICS
- Collagen type I regulates β-catenin tyrosine phosphorylation and nuclear translocation to promote migration and proliferation of gastric carcinoma cells
- (2010) Si ONCOLOGY REPORTS
- Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-
- (2010) M. Kraman et al. SCIENCE
- Type IV collagen is a tumour stroma-derived biomarker for pancreas cancer
- (2009) D Öhlund et al. BRITISH JOURNAL OF CANCER
- Tumor stroma derived biomarkers in cancer
- (2009) Malin Sund et al. CANCER AND METASTASIS REVIEWS
- Signal transduction by focal adhesion kinase in cancer
- (2009) Jihe Zhao et al. CANCER AND METASTASIS REVIEWS
- Mechanics, malignancy, and metastasis: The force journey of a tumor cell
- (2009) Sanjay Kumar et al. CANCER AND METASTASIS REVIEWS
- Targeting transforming growth factor-β signaling in liver metastasis of colon cancer
- (2009) Bixiang Zhang et al. CANCER LETTERS
- Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
- (2009) Laetitia Devy et al. CANCER RESEARCH
- Pulmonary Vascular Destabilization in the Premetastatic Phase Facilitates Lung Metastasis
- (2009) Y. Huang et al. CANCER RESEARCH
- Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
- (2009) Kandice R. Levental et al. CELL
- Serum levels of matrix metalloproteinase-2 and -9 and conventional tumor markers (CEA and CA 19-9) in patients with colorectal and gastric cancers
- (2009) Marwan Emara et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- The extracellular matrix in development and morphogenesis: A dynamic view
- (2009) Tania Rozario et al. DEVELOPMENTAL BIOLOGY
- Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma
- (2009) S. A. Arnold et al. Disease Models & Mechanisms
- Down-regulation of connective tissue growth factor by inhibition of transforming growth factor β blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma
- (2009) Antonio Mazzocca et al. HEPATOLOGY
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures
- (2009) E. Van Goethem et al. JOURNAL OF IMMUNOLOGY
- Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage
- (2009) P P Provenzano et al. ONCOGENE
- Clinical Significance of the Measurements of Serum Matrix Metalloproteinase-9 and Its Inhibitor (Tissue Inhibitor of Metalloproteinase-1) in Patients With Pancreatic Cancer
- (2009) Barbara Mroczko et al. PANCREAS
- Promotion of Tumor Cell Migration by Extracellular Matrix Proteins in Human Pancreatic Cancer
- (2009) Eduard Ryschich et al. PANCREAS
- The Extracellular Matrix: Not Just Pretty Fibrils
- (2009) R. O. Hynes SCIENCE
- Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
- (2009) K. P. Olive et al. SCIENCE
- Shedding microvesicles: artefacts no more
- (2009) Emanuele Cocucci et al. TRENDS IN CELL BIOLOGY
- Interactions between extracellular matrix and growth factors in wound healing
- (2009) Gregory S. Schultz et al. WOUND REPAIR AND REGENERATION
- Diverse Cell Signaling Events Modulated by Perlecan†
- (2008) John M. Whitelock et al. BIOCHEMISTRY
- Collagen IV levels are elevated in the serum of patients with primary breast cancer compared to healthy volunteers
- (2008) C Mazouni et al. BRITISH JOURNAL OF CANCER
- Laminin-332 promotes the invasion of oesophageal squamous cell carcinoma via PI3K activation
- (2008) Y Baba et al. BRITISH JOURNAL OF CANCER
- The role of endothelial-to-mesenchymal transition in cancer progression
- (2008) S Potenta et al. BRITISH JOURNAL OF CANCER
- Activation of fibronectin/PI-3K/Akt2 leads to chemoresistance to docetaxel by regulating survivin protein expression in ovarian and breast cancer cells
- (2008) Hui Xing et al. CANCER LETTERS
- Three-dimensional context regulation of metastasis
- (2008) Janine T. Erler et al. CLINICAL & EXPERIMENTAL METASTASIS
- Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer
- (2008) J. M. Bailey et al. CLINICAL CANCER RESEARCH
- The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma
- (2008) Mert Erkan et al. Clinical Gastroenterology and Hepatology
- Forced Expression of MMP9 Rescues the Loss of Angiogenesis and Abrogates Metastasis of Pancreatic Tumors Triggered by the Absence of Host SPARC
- (2008) Shanna Arnold et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes
- (2008) Juha Hakulinen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- A paracrine requirement for hedgehog signalling in cancer
- (2008) Robert L. Yauch et al. NATURE
- Rapid leukocyte migration by integrin-independent flowing and squeezing
- (2008) Tim Lämmermann et al. NATURE
- Interstitial leukocyte migration and immune function
- (2008) Peter Friedl et al. NATURE IMMUNOLOGY
- Enhanced macromolecule diffusion deep in tumors after enzymatic digestion of extracellular matrix collagen and its associated proteoglycan decorin
- (2007) Mazin Magzoub et al. FASEB JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More