Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma

Current and future biomarkers for pancreatic adenocarcinoma

(2017) Sven H Loosen et al.   TUMOR BIOLOGY

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

(2016) Hong Jiang et al.   NATURE MEDICINE

PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma

(2016) Rajani Kanteti et al.   Scientific Reports

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nuclear FAK Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity

(2015) Alan Serrels et al.   CELL

A phase I study of VS-6063, a second-generation focal adhesion kinase inhibitor, in patients with advanced solid tumors

(2015) Suzanne F. Jones et al.   INVESTIGATIONAL NEW DRUGS

A Role for the Tyrosine Kinase Pyk2 in Depolarization-induced Contraction of Vascular Smooth Muscle

(2015) Ryan D. Mills et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Whole genomes redefine the mutational landscape of pancreatic cancer

(2015) Nicola Waddell et al.   NATURE

A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells

(2014) Jianliang Zhang et al.   CELL CYCLE

MET and PI3K/mTOR as a Potential Combinatorial Therapeutic Target in Malignant Pleural Mesothelioma

(2014) Rajani Kanteti et al.   PLoS One

Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship

(2014) I. M. Shapiro et al.   Science Translational Medicine

Electric Cell-substrate Impedance Sensing for the Quantification of Endothelial Proliferation, Barrier Function, and Motility

(2014) Robert Szulcek et al.   Jove-Journal of Visualized Experiments

Alcohol consumption on pancreatic diseases

(2013) Marta Herreros-Villanueva   WORLD JOURNAL OF GASTROENTEROLOGY

Focal Adhesion Kinase: From In Vitro Studies to Functional Analyses In Vivo

(2012) Xu Peng et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Tenascin C Induces Epithelial-Mesenchymal Transition–Like Change Accompanied by SRC Activation and Focal Adhesion Kinase Phosphorylation in Human Breast Cancer Cells

(2011) Keiki Nagaharu et al.   AMERICAN JOURNAL OF PATHOLOGY

Focal adhesion kinase inhibitors are potent anti-angiogenic agents

(2011) Miguel A. Cabrita et al.   Molecular Oncology

Evaluation of the Clinical Significance of Focal Adhesion Kinase and Src Expression in Human Pancreatic Ductal Adenocarcinoma

(2010) Nikolaos A. Chatzizacharias et al.   PANCREAS

The direct effect of Focal Adhesion Kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis

(2009) Vita M Golubovskaya et al.   BMC CANCER

Signal transduction by focal adhesion kinase in cancer

(2009) Jihe Zhao et al.   CANCER AND METASTASIS REVIEWS

The Convergence of Lung Cancer Rates between Blacks and Whites under the Age of 40, United States

(2009) A. Jemal et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Pancreatic cancer: molecular pathogenesis and new therapeutic targets

(2009) Han H. Wong et al.   Nature Reviews Gastroenterology & Hepatology

Dual Tyrosine Kinase Inhibitor for Focal Adhesion Kinase and Insulin-like Growth Factor-I Receptor Exhibits Anticancer Effect in Esophageal Adenocarcinoma In vitro and In vivo

(2008) N. Watanabe et al.   CLINICAL CANCER RESEARCH

A Small Molecule Inhibitor, 1,2,4,5-Benzenetetraamine Tetrahydrochloride, Targeting the Y397 Site of Focal Adhesion Kinase Decreases Tumor Growth

(2008) Vita M. Golubovskaya et al.   JOURNAL OF MEDICINAL CHEMISTRY

Focal Adhesion Kinase Versus p53: Apoptosis or Survival?

(2008) W. G. Cance et al.   Science Signaling