Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

Physical confinement alters tumor cell adhesion and migration phenotypes

(2012) Eric M. Balzer et al.   FASEB JOURNAL

Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors

(2012) Hélène Salmon et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemotaxis of Cell Populations through Confined Spaces at Single-Cell Resolution

(2012) ZiQiu Tong et al.   PLoS One

Elucidating the Role of Matrix Stiffness in 3D Cell Migration and Remodeling

(2011) M. Ehrbar et al.   BIOPHYSICAL JOURNAL

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Extracellular matrix determinants of proteolytic and non-proteolytic cell migration

(2011) Katarina Wolf et al.   TRENDS IN CELL BIOLOGY

Interlaboratory round robin on cantilever calibration for AFM force spectroscopy

(2011) Joost te Riet et al.   ULTRAMICROSCOPY

Cell Motility and Mechanics in Three-Dimensional Collagen Matrices

(2010) Frederick Grinnell et al.   Annual Review of Cell and Developmental Biology

Pore size variable type I collagen gels and their interaction with glioma cells

(2010) Ya-li Yang et al.   BIOMATERIALS

The differential regulation of cell motile activity through matrix stiffness and porosity in three dimensional collagen matrices

(2010) Miguel Miron-Mendoza et al.   BIOMATERIALS

A Blind Spot in Confocal Reflection Microscopy: The Dependence of Fiber Brightness on Fiber Orientation in Imaging Biopolymer Networks

(2010) Louise M. Jawerth et al.   BIOPHYSICAL JOURNAL

Pseudopodial Actin Dynamics Control Epithelial-Mesenchymal Transition in Metastatic Cancer Cells

(2010) Jay Shankar et al.   CANCER RESEARCH

Nuclear mechanics during cell migration

(2010) Peter Friedl et al.   CURRENT OPINION IN CELL BIOLOGY

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia

(2010) Marie Schoumacher et al.   JOURNAL OF CELL BIOLOGY

Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?

(2010) A. Buxboim et al.   JOURNAL OF CELL SCIENCE

Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA–regulated adhesions

(2010) Jordan Jacobelli et al.   NATURE IMMUNOLOGY

Impact of Tumor Cell Cytoskeleton Organization on Invasiveness and Migration: A Microchannel-Based Approach

(2010) Claudio G. Rolli et al.   PLoS One

The role of chromatin structure in cell migration

(2010) Gabi Gerlitz et al.   TRENDS IN CELL BIOLOGY

Navigating ECM Barriers at the Invasive Front: The Cancer Cell–Stroma Interface

(2009) R. Grant Rowe et al.   Annual Review of Cell and Developmental Biology

Monocytes and Neutrophils Exhibit Both Distinct and Common Mechanisms in Penetrating the Vascular Basement Membrane In Vivo

(2009) Mathieu-Benoît Voisin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rheology and Confocal Reflectance Microscopy as Probes of Mechanical Properties and Structure during Collagen and Collagen/Hyaluronan Self-Assembly

(2009) Ya-li Yang et al.   BIOPHYSICAL JOURNAL

Proteolytic interstitial cell migration: a five-step process

(2009) Peter Friedl et al.   CANCER AND METASTASIS REVIEWS

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Modulation of the Membrane Type 1 Matrix Metalloproteinase Cytoplasmic Tail Enhances Tumor Cell Invasion and Proliferation in Three-dimensional Collagen Matrices

(2009) Natalie M. Moss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

The mechanical integrin cycle

(2009) E. Puklin-Faucher et al.   JOURNAL OF CELL SCIENCE

MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices

(2009) Kevin E. Fisher et al.   JOURNAL OF CELL SCIENCE

The Tumor Suppressor Functions of p27kip1 Include Control of the Mesenchymal/Amoeboid Transition

(2009) S. Berton et al.   MOLECULAR AND CELLULAR BIOLOGY

The regulatory role of cell mechanics for migration of differentiating myeloid cells

(2009) F. Lautenschlager et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collagen-based cell migration models in vitro and in vivo

(2009) Katarina Wolf et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Collagen I but not Matrigel matrices provide an MMP-dependent barrier to ovarian cancer cell penetration

(2008) Katharine L Sodek et al.   BMC CANCER

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model

(2008) Stephanie Alexander et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Segregation and activation of myosin IIB creates a rear in migrating cells

(2008) Miguel Vicente-Manzanares et al.   JOURNAL OF CELL BIOLOGY

Filaments made from A- and B-type lamins differ in structure and organization

(2008) M. W. Goldberg et al.   JOURNAL OF CELL SCIENCE

An algorithm for extracting the network geometry of three-dimensional collagen gels

(2008) ANDREW M. STEIN et al.   JOURNAL OF MICROSCOPY

Direct visualization of protease activity on cells migrating in three-dimensions

(2008) Beverly Z. Packard et al.   MATRIX BIOLOGY

The Role of Myosin II in Glioma Invasion of the Brain

(2008) Christopher Beadle et al.   MOLECULAR BIOLOGY OF THE CELL

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE