Hallmarks of neurodegenerative diseases

Neuroinflammation PET imaging of the translocator protein (TSPO) in Alzheimer's disease: An update

(2022) Dominique Gouilly et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

(2022) Willemijn J. Jansen et al.   JAMA Neurology

Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration

(2022) Manish Verma et al.   Translational Neurodegeneration

The needs of a synapse—How local organelles serve synaptic proteostasis

(2022) Katarzyna M Grochowska et al.   EMBO JOURNAL

Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility

(2022) Thomas K. Karikari et al.   Nature Reviews Neurology

Macroautophagy in CNS health and disease

(2022) Christopher J. Griffey et al.   NATURE REVIEWS NEUROSCIENCE

Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol

(2021) Juan Carlos Polanco et al.   ACTA NEUROPATHOLOGICA

Alzheimer's disease

(2021) Philip Scheltens et al.   LANCET

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

(2021) Ruth Chia et al.   NATURE GENETICS

Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation

(2021) Paraskevi Tziortzouda et al.   NATURE REVIEWS NEUROSCIENCE

Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome

(2021) Mathieu Bourdenx et al.   CELL

Alzheimer disease

(2021) David S. Knopman et al.   Nature Reviews Disease Primers

Peripheral and central immune system crosstalk in Alzheimer disease — a research prospectus

(2021) Brianne M. Bettcher et al.   Nature Reviews Neurology

C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation

(2021) Deepti Lall et al.   NEURON

Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology

(2021) Tanima SenGupta et al.   Cell Reports

α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes

(2021) Aysegul Dilsizoglu Senol et al.   PLOS BIOLOGY

Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease

(2021) Shorena Janelidze et al.   JAMA Neurology

Reduced C9orf72 function leads to defective synaptic vesicle release and neuromuscular dysfunction in zebrafish

(2021) Zoé Butti et al.   Communications Biology

Mechanism-based criteria to improve therapeutic outcomes in progressive multiple sclerosis

(2021) Heather Y. F. Yong et al.   Nature Reviews Neurology

Energy matters: presynaptic metabolism and the maintenance of synaptic transmission

(2021) Sunan Li et al.   NATURE REVIEWS NEUROSCIENCE

DNA damage and repair in Parkinson's disease: Recent advances and new opportunities

(2020) Claudia P. Gonzalez‐Hunt et al.   JOURNAL OF NEUROSCIENCE RESEARCH

ATP13A2 deficiency disrupts lysosomal polyamine export

(2020) Sarah van Veen et al.   NATURE

APOE genotype regulates pathology and disease progression in synucleinopathy

(2020) Albert A. Davis et al.   Science Translational Medicine

Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances

(2020) Wenzhang Wang et al.   Molecular Neurodegeneration

The Journey of the Synaptic Autophagosome: A Cell Biological Perspective

(2020) Sarah E. Hill et al.   NEURON

Dynamic microtubules at the synapse

(2020) Erik W Dent   CURRENT OPINION IN NEUROBIOLOGY

Self-Eating for Muscle Fitness: Autophagy in the Control of Energy Metabolism

(2020) David Sebastián et al.   DEVELOPMENTAL CELL

LRRK 2 activation controls the repair of damaged endomembranes in macrophages

(2020) Susanne Herbst et al.   EMBO JOURNAL

Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease

(2020) Simon Dujardin et al.   NATURE MEDICINE

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

(2020) Stephen C. Cunnane et al.   NATURE REVIEWS DRUG DISCOVERY

Proteopathic Seed Amplification Assays for Neurodegenerative Disorders

(2020) Natália do Carmo Ferreira et al.   CLINICS IN LABORATORY MEDICINE

Impact of TREM2R47H variant on tau pathology–induced gliosis and neurodegeneration

(2020) Maud Gratuze et al.   JOURNAL OF CLINICAL INVESTIGATION

Tau Pathology Triggered by Spinal Cord Injury Can Play a Critical Role in the Neurotrauma Development

(2020) Elnaz Nakhjiri et al.   MOLECULAR NEUROBIOLOGY

DNA Double-Strand Break Accumulation in Alzheimer’s Disease: Evidence from Experimental Models and Postmortem Human Brains

(2020) Nidheesh Thadathil et al.   MOLECULAR NEUROBIOLOGY

ALS Genetics: Gains, Losses, and Implications for Future Therapies

(2020) Garam Kim et al.   NEURON

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

(2019) Joy Mitra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disorders

(2019) Alessandro Didonna et al.   Molecular Neurodegeneration

Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions

(2019) Julia K. Nussbacher et al.   NEURON

Targeting microglia in brain disorders

(2019) Josef Priller et al.   SCIENCE

DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging

(2019) Vinod Tiwari et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

(2019) Renzo Mancuso et al.   BRAIN

Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer’s disease

(2019) Michael Ewers et al.   Science Translational Medicine

Axonal transport defects and neurodegeneration: Molecular mechanisms and therapeutic implications

(2019) Wenting Guo et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer’s and Parkinson’s disease

(2019) Simon Sjödin et al.   Alzheimers Research & Therapy

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

NAD+ in Brain Aging and Neurodegenerative Disorders

(2019) Sofie Lautrup et al.   Cell Metabolism

RNA toxicity in non‐coding repeat expansion disorders

(2019) Bart Swinnen et al.   EMBO JOURNAL

Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model

(2019) Yang Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stress granules and neurodegeneration

(2019) Benjamin Wolozin et al.   NATURE REVIEWS NEUROSCIENCE

Cellular quality control by the ubiquitin-proteasome system and autophagy

(2019) Christian Pohl et al.   SCIENCE

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

(2019) Elizabeth Spangenberg et al.   Nature Communications

Energy metabolism in ALS: an underappreciated opportunity?

(2018) Tijs Vandoorne et al.   ACTA NEUROPATHOLOGICA

Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD

(2018) Alexander Starr et al.   BRAIN RESEARCH

Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases

(2018) Chao Wang et al.   CURRENT OPINION IN NEUROBIOLOGY

High performance plasma amyloid-β biomarkers for Alzheimer’s disease

(2018) Akinori Nakamura et al.   NATURE

Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy

(2018) Krista J. Spiller et al.   NATURE NEUROSCIENCE

Prions, prionoids and protein misfolding disorders

(2018) Claudia Scheckel et al.   NATURE REVIEWS GENETICS

Mitochondria at the neuronal presynapse in health and disease

(2018) Michael J. Devine et al.   NATURE REVIEWS NEUROSCIENCE

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

(2018) Aude Nicolas et al.   NEURON

α-Synuclein and Tau: Mitochondrial Kill Switches

(2018) Ulrike Pech et al.   NEURON

Neuronal Cell Death

(2018) Michael Fricker et al.   PHYSIOLOGICAL REVIEWS

Polyglutamine Repeats in Neurodegenerative Diseases

(2018) Andrew P. Lieberman et al.   Annual Review of Pathology-Mechanisms of Disease

Parkinson's disease: convergence on synaptic homeostasis

(2018) Sandra‐Fausia Soukup et al.   EMBO JOURNAL

Converging pathways in neurodegeneration, from genetics to mechanisms

(2018) Li Gan et al.   NATURE NEUROSCIENCE

Microglia in neurodegeneration

(2018) Suzanne Hickman et al.   NATURE NEUROSCIENCE

Neurofilaments as biomarkers in neurological disorders

(2018) Michael Khalil et al.   Nature Reviews Neurology

Inflammasome signalling in brain function and neurodegenerative disease

(2018) Michael T. Heneka et al.   NATURE REVIEWS NEUROSCIENCE

Imaging the evolution and pathophysiology of Alzheimer disease

(2018) William Jagust   NATURE REVIEWS NEUROSCIENCE

Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia

(2018) Jack Brelstaff et al.   Cell Reports

Molecular Pathogenesis of the Tauopathies

(2018) Jürgen Götz et al.   Annual Review of Pathology-Mechanisms of Disease

Biomarkers for tau pathology

(2018) Michael Schöll et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Multiple sclerosis

(2018) Massimo Filippi et al.   Nature Reviews Disease Primers

Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations

(2018) Masashi Takanashi et al.   Acta Neuropathologica Communications

Genome integrity and disease prevention in the nervous system

(2017) Peter J. McKinnon   GENES & DEVELOPMENT

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Autophagy in the presynaptic compartment in health and disease

(2017) Vinoy Vijayan et al.   JOURNAL OF CELL BIOLOGY

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

(2017) Steven Boeynaems et al.   MOLECULAR CELL

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies

(2017) Yvette C Wong et al.   NATURE MEDICINE

Not just amyloid: physiological functions of the amyloid precursor protein family

(2017) Ulrike C. Müller et al.   NATURE REVIEWS NEUROSCIENCE

The two-century journey of Parkinson disease research

(2017) Serge Przedborski   NATURE REVIEWS NEUROSCIENCE

Selective neuronal vulnerability in Parkinson disease

(2017) D. James Surmeier et al.   NATURE REVIEWS NEUROSCIENCE

Progranulin, lysosomal regulation and neurodegenerative disease

(2017) Aimee W. Kao et al.   NATURE REVIEWS NEUROSCIENCE

The nano-architecture of the axonal cytoskeleton

(2017) Christophe Leterrier et al.   NATURE REVIEWS NEUROSCIENCE

Polyglutamine spinocerebellar ataxias — from genes to potential treatments

(2017) Henry L. Paulson et al.   NATURE REVIEWS NEUROSCIENCE

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

(2017) Fiona M. Menzies et al.   NEURON

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants

(2017) Katie J. Ryan et al.   Science Translational Medicine

Pathology of Neurodegenerative Diseases

(2017) Brittany N. Dugger et al.   Cold Spring Harbor Perspectives in Biology

Clinical Neurology and Epidemiology of the Major Neurodegenerative Diseases

(2017) Michael G. Erkkinen et al.   Cold Spring Harbor Perspectives in Biology

Neurofilaments and Neurofilament Proteins in Health and Disease

(2017) Aidong Yuan et al.   Cold Spring Harbor Perspectives in Biology

Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease

(2017) Chenjie Xia et al.   JAMA Neurology

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

(2017) Rachel E. Lackie et al.   Frontiers in Neuroscience

Traumatic spinal cord injury

(2017) Christopher S. Ahuja et al.   Nature Reviews Disease Primers

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

Synaptic pathology: A shared mechanism in neurological disease

(2016) Christopher M. Henstridge et al.   AGEING RESEARCH REVIEWS

The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis

(2016) Han-Jou Chen et al.   BRAIN

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

(2016) Hansen Lui et al.   CELL

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles

(2016) Kyung-Ha Lee et al.   CELL

The frontotemporal dementia-motor neuron disease continuum

(2016) James R Burrell et al.   LANCET

Synaptic failure and α-synuclein

(2016) Laura Calo et al.   MOVEMENT DISORDERS

Decoding ALS: from genes to mechanism

(2016) J. Paul Taylor et al.   NATURE

Defects in trafficking bridge Parkinson's disease pathology and genetics

(2016) Asa Abeliovich et al.   NATURE

Pathophysiological and diagnostic implications of cortical dysfunction in ALS

(2016) Nimeshan Geevasinga et al.   Nature Reviews Neurology

The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease

(2016) Aaron R. Haeusler et al.   NATURE REVIEWS NEUROSCIENCE

Network abnormalities and interneuron dysfunction in Alzheimer disease

(2016) Jorge J. Palop et al.   NATURE REVIEWS NEUROSCIENCE

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

Imaging synaptic density in the living human brain

(2016) Sjoerd J. Finnema et al.   Science Translational Medicine

Molecular Genetics of Neurodegenerative Dementias

(2016) Flora I. Hinz et al.   Cold Spring Harbor Perspectives in Biology

Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease

(2016) Sara Sepe et al.   Cell Reports

Huntington’s Disease: Mechanisms of Pathogenesis and Therapeutic Strategies

(2016) Maria Jimenez-Sanchez et al.   Cold Spring Harbor Perspectives in Medicine

Traumatic brain injuries

(2016) Kaj Blennow et al.   Nature Reviews Disease Primers

Mitochondrial diseases

(2016) Gráinne S. Gorman et al.   Nature Reviews Disease Primers

Neurodegenerative Diseases: Expanding the Prion Concept

(2015) Lary C. Walker et al.   Annual Review of Neuroscience

Frontotemporal dementia

(2015) Jee Bang et al.   LANCET

C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis

(2015) Jonathan D Rohrer et al.   LANCET NEUROLOGY

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

DNA damage in neurodegenerative diseases

(2015) Fabio Coppedè et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling

(2015) Natura Myeku et al.   NATURE MEDICINE

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

(2015) Erik S Musiek et al.   NATURE NEUROSCIENCE

Do glia drive synaptic and cognitive impairment in disease?

(2015) Won-Suk Chung et al.   NATURE NEUROSCIENCE

Synaptopathy connects inflammation and neurodegeneration in multiple sclerosis

(2015) Georgia Mandolesi et al.   Nature Reviews Neurology

Compromised autophagy and neurodegenerative diseases

(2015) Fiona M. Menzies et al.   NATURE REVIEWS NEUROSCIENCE

The connectomics of brain disorders

(2015) Alex Fornito et al.   NATURE REVIEWS NEUROSCIENCE

Building the Neuronal Microtubule Cytoskeleton

(2015) Lukas C. Kapitein et al.   NEURON

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

(2015) Alicia M. Pickrell et al.   NEURON

Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled A , tau, and  -synuclein

(2015) M. Goedert   SCIENCE

Astrocytes in Neurodegenerative Disease: Table 1.

(2015) Hemali Phatnani et al.   Cold Spring Harbor Perspectives in Biology

Huntington disease

(2015) Gillian P. Bates et al.   Nature Reviews Disease Primers

Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration

(2015) Jorge Gomez-Deza et al.   Acta Neuropathologica Communications

DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes

(2015) Peter Sykora et al.   NUCLEIC ACIDS RESEARCH

Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion

(2014) S. E. Lee et al.   BRAIN

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

(2014) Haiyan Qiu et al.   JOURNAL OF CLINICAL INVESTIGATION

Hsp90 Chaperone Inhibitor 17-AAG Attenuates A -Induced Synaptic Toxicity and Memory Impairment

(2014) Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Neuroimaging in amyotrophic lateral sclerosis: insights into structural and functional changes

(2014) Adriano Chiò et al.   LANCET NEUROLOGY

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

(2014) Andrea Crotti et al.   NATURE NEUROSCIENCE

Wallerian degeneration: an emerging axon death pathway linking injury and disease

(2014) Laura Conforti et al.   NATURE REVIEWS NEUROSCIENCE

Modern network science of neurological disorders

(2014) Cornelis J. Stam   NATURE REVIEWS NEUROSCIENCE

DNA Damage and Its Links to Neurodegeneration

(2014) Ram Madabhushi et al.   NEURON

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

Astrogliosis

(2014) Michael V. Sofroniew   Cold Spring Harbor Perspectives in Biology

Glutathione and mitochondria

(2014) Vicent Ribas et al.   Frontiers in Pharmacology

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

The changing scene of amyotrophic lateral sclerosis

(2013) Wim Robberecht et al.   NATURE REVIEWS NEUROSCIENCE

The Function of α-Synuclein

(2013) Jacob T. Bendor et al.   NEURON

Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis

(2013) Shuo-Chien Ling et al.   NEURON

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

RNA That Gets RAN in Neurodegeneration

(2013) J. P. Taylor   SCIENCE

The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS

(2013) K. Mori et al.   SCIENCE

Autophagy in axonal and dendritic degeneration

(2013) Yi Yang et al.   TRENDS IN NEUROSCIENCES

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

The Genetics of Alzheimer Disease

(2013) R. E. Tanzi   Cold Spring Harbor Perspectives in Medicine

Autophagy in lysosomal storage disorders

(2012) Andrew P. Lieberman et al.   Autophagy

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Regulated protein aggregation: stress granules and neurodegeneration

(2012) Benjamin Wolozin   Molecular Neurodegeneration

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

100 years of Lewy pathology

(2012) Michel Goedert et al.   Nature Reviews Neurology

Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration

(2012) Zu-Hang Sheng et al.   NATURE REVIEWS NEUROSCIENCE

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

The Neuropathology and Neurobiology of Traumatic Brain Injury

(2012) Kaj Blennow et al.   NEURON

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease

(2011) Thomas Philips et al.   LANCET NEUROLOGY

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

(2011) Han-Xiang Deng et al.   NATURE

Mitochondria: The Next (Neurode)Generation

(2011) Eric A. Schon et al.   NEURON

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

(2011) Laura A. Volpicelli-Daley et al.   NEURON

The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia

(2010) Walter J. Schulz-Schaeffer   ACTA NEUROPATHOLOGICA

Clinical progression in Parkinson disease and the neurobiology of axons

(2010) Hsiao-Chun Cheng et al.   ANNALS OF NEUROLOGY

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

(2010) Janel O. Johnson et al.   NEURON

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

The intricate mechanisms of neurodegeneration in prion diseases

(2010) Claudio Soto et al.   TRENDS IN MOLECULAR MEDICINE

Roles of trinucleotide-repeat RNA in neurological disease and degeneration

(2010) Ling-Bo Li et al.   TRENDS IN NEUROSCIENCES

The propagation of prion-like protein inclusions in neurodegenerative diseases

(2010) Michel Goedert et al.   TRENDS IN NEUROSCIENCES

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update

(2009) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

A critical evaluation of the ubiquitin–proteasome system in Parkinson's disease

(2009) Casey Cook et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

(2009) Hui Xiong et al.   JOURNAL OF CLINICAL INVESTIGATION

Axonal Transport Defects in Neurodegenerative Diseases

(2009) G. A. Morfini et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial membrane permeabilization in neuronal injury

(2009) Lorenzo Galluzzi et al.   NATURE REVIEWS NEUROSCIENCE

Neurodegenerative Diseases Target Large-Scale Human Brain Networks

(2009) William W. Seeley et al.   NEURON

Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis

(2008) J. M. Anderson et al.   BRAIN

Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

(2008) Lorenzo A. Cingolani et al.   NATURE REVIEWS NEUROSCIENCE

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS