Neurofilaments and Neurofilament Proteins in Health and Disease

Intermediate Filaments: Structure and Assembly

(2016) Harald Herrmann et al.   Cold Spring Harbor Perspectives in Biology

Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression

(2016) Henrik Zetterberg et al.   JAMA Neurology

Serum Levels of Neurofilament-H are Elevated in Patients Suffering From Severe Burns

(2015) Joshua W. Gatson et al.   Journal of Burn Care & Research

Functions of neurofilaments in synapses

(2015) A Yuan et al.   MOLECULAR PSYCHIATRY

Neurofilament subunits are integral components of synapses and modulate neurotransmission and behavior in vivo

(2015) A Yuan et al.   MOLECULAR PSYCHIATRY

Dissociation of Axonal Neurofilament Content from Its Transport Rate

(2015) Aidong Yuan et al.   PLoS One

Composite bottlebrush mechanics: α-internexin fine-tunes neurofilament network properties

(2015) M. Kornreich et al.   Soft Matter

Multimotor Transport in a System of Active and Inactive Kinesin-1 Motors

(2014) Lara Scharrel et al.   BIOPHYSICAL JOURNAL

PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology

(2014) Tsz Hang Wong et al.   BRAIN

Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome

(2014) J. Kuhle et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration

(2013) Carole S. Scherling et al.   ANNALS OF NEUROLOGY

Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport

(2013) Diana Zala et al.   CELL

Giant axonal neuropathy–associated gigaxonin mutations impair intermediate filament protein degradation

(2013) Saleemulla Mahammad et al.   JOURNAL OF CLINICAL INVESTIGATION

Toxic neurofilamentous axonopathies- accumulation of neurofilaments and axonal degeneration

(2013) J. Llorens   JOURNAL OF INTERNAL MEDICINE

Neurofilament-tubulin binding site peptide NFL-TBS.40-63 increases the differentiation of oligodendrocytes in vitro and partially prevents them from lysophosphatidyl choline toxiciy

(2013) Catherine Fressinaud et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases

(2013) Johanna Gaiottino et al.   PLoS One

Severing and end-to-end annealing of neurofilaments in neurons

(2013) A. Uchida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Charcot–Marie–Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin

(2012) Laura Cogli et al.   ACTA NEUROPATHOLOGICA

Interference with kinesin-based anterograde neurofilament axonal transport increases neurofilament-neurofilament bundling

(2012) Neethu Sunil et al.   Cytoskeleton

2,5-Hexanedione altered the degradation of low-molecular-weight neurofilament in rat nerve tissues

(2012) Fuyong Song et al.   FOOD AND CHEMICAL TOXICOLOGY

14-3-3 proteins interact with neurofilament protein-L and regulate dynamic assembly of neurofilaments

(2012) L. Miao et al.   JOURNAL OF CELL SCIENCE

Neurofilaments at a glance

(2012) A. Yuan et al.   JOURNAL OF CELL SCIENCE

Axonal Transport of Neurofilaments: A Single Population of Intermittently Moving Polymers

(2012) Y. Li et al.   JOURNAL OF NEUROSCIENCE

Peripherin Is a Subunit of Peripheral Nerve Neurofilaments: Implications for Differential Vulnerability of CNS and Peripheral Nervous System Axons

(2012) A. Yuan et al.   JOURNAL OF NEUROSCIENCE

Arrest of Myelination and Reduced Axon Growth When Schwann Cells Lack mTOR

(2012) D. L. Sherman et al.   JOURNAL OF NEUROSCIENCE

A Tubulin Binding Peptide Targets Glioma Cells Disrupting Their Microtubules, Blocking Migration, and Inducing Apoptosis

(2012) Raphael Berges et al.   MOLECULAR THERAPY

Neurofilaments as biomarkers in multiple sclerosis

(2012) Charlotte E Teunissen et al.   Multiple Sclerosis Journal

The C-Terminal Domains of NF-H and NF-M Subunits Maintain Axonal Neurofilament Content by Blocking Turnover of the Stationary Neurofilament Network

(2012) Mala V. Rao et al.   PLoS One

Phosphatidylinositol phosphates directly bind to neurofilament light chain (NF-L) for the regulation of NF-L self assembly

(2011) Sung-Kuk Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Normal role of the low-molecular-weight neurofilament protein in mitochondrial dynamics and disruption in Charcot-Marie-Tooth disease

(2011) Benoit J. Gentil et al.   FASEB JOURNAL

Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice

(2011) Thibault Ganay et al.   Molecular Neurodegeneration

The Myosin Va Head Domain Binds to the Neurofilament-L Rod and Modulates Endoplasmic Reticulum (ER) Content and Distribution within Axons

(2011) Mala V. Rao et al.   PLoS One

Multiple neurofilament subunits are present in lamprey CNS

(2010) Li-Qing Jin et al.   BRAIN RESEARCH

How the projection domains of NF-L and α-internexin determine the conformations of NF-M and NF-H in neurofilaments

(2010) F. A. M. Leermakers et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport

(2010) Lina Wang et al.   Molecular Neurodegeneration

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

A novel recessiveNeflmutation causes a severe, early-onset axonal neuropathy

(2009) Sabrina W. Yum et al.   ANNALS OF NEUROLOGY

Variation of the neurofilament medium KSP repeat sub-domain across mammalian species: implications for altering axonal structure

(2009) D. M. Barry et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Neurofilament light chain polypeptide gene mutations in Charcot–Marie–Tooth disease: nonsense mutation probably causes a recessive phenotype

(2009) Akiko Abe et al.   JOURNAL OF HUMAN GENETICS

Immunoreactivity of the phosphorylated axonal neurofilament H subunit (pNF-H) in blood of ALS model rodents and ALS patients: evaluation of blood pNF-H as a potential ALS biomarker

(2009) Kevin Boylan et al.   JOURNAL OF NEUROCHEMISTRY

Myosin Va Increases the Efficiency of Neurofilament Transport by Decreasing the Duration of Long-Term Pauses

(2009) N. H. Alami et al.   JOURNAL OF NEUROSCIENCE

Neurofilaments Form a Highly Stable Stationary Cytoskeleton after Reaching a Critical Level in Axons

(2009) A. Yuan et al.   JOURNAL OF NEUROSCIENCE

Neurofilaments Bind Tubulin and Modulate Its Polymerization

(2009) A. Bocquet et al.   JOURNAL OF NEUROSCIENCE

Tight Functional Coupling of Kinesin-1A and Dynein Motors in the Bidirectional Transport of Neurofilaments

(2009) Atsuko Uchida et al.   MOLECULAR BIOLOGY OF THE CELL

Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments

(2009) Veeranna et al.   NEUROBIOLOGY OF AGING

MSC p43 required for axonal development in motor neurons

(2009) X. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myosin Vb Mobilizes Recycling Endosomes and AMPA Receptors for Postsynaptic Plasticity

(2008) Zhiping Wang et al.   CELL

Intermediate filaments: versatile building blocks of cell structure

(2008) Robert D Goldman et al.   CURRENT OPINION IN CELL BIOLOGY

The Phosphorylated Axonal Form of the Neurofilament Subunit NF-H (pNF-H) as a Blood Biomarker of Traumatic Brain Injury

(2008) Kevin J. Anderson et al.   JOURNAL OF NEUROTRAUMA

A quantitative examination of the role of cargo-exerted forces in axonal transport

(2008) Cassie S. Mitchell et al.   JOURNAL OF THEORETICAL BIOLOGY

Review of the Multiple Aspects of Neurofilament Functions, and their Possible Contribution to Neurodegeneration

(2008) Rodolphe Perrot et al.   MOLECULAR NEUROBIOLOGY

Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration

(2008) M. Balastik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA